-
1
-
-
33750454570
-
-
Panel on Antiretroviral Guidelines for Adult and Adolescents. Department of Health and Human Services
-
Panel on Antiretroviral Guidelines for Adult and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services 2008, 1-128 http://aidsinfo.nih.gov/Guidelines
-
(2008)
Guidelines for the Use of Antiretroviral Agents in HIV-1-infected Adults and Adolescents
, pp. 1-128
-
-
-
2
-
-
0033935975
-
Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity
-
10.1016/S0149-2918(00)90004-3 10929917
-
Kakuda TN Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity Clin Ther 2000, 22:685-708 10.1016/S0149-2918(00)90004-3 10929917
-
(2000)
Clin Ther
, vol.22
, pp. 685-708
-
-
Kakuda, T.N.1
-
3
-
-
0036114874
-
Therapeutic drug monitoring in HIV infection: Current status and future directions
-
10.1097/00002030-200203001-00002 12035820
-
Back D Gatti G Fletcher C Garaffo R Haubrich R Hoetelmans R Kurowski M Luber A Merry C Perno CF Therapeutic drug monitoring in HIV infection: current status and future directions AIDS 2002, 16(Suppl 1):S5-37 10.1097/00002030-200203001-00002 12035820
-
(2002)
AIDS
, vol.16
, Issue.SUPPL. 1
-
-
Back, D.1
Gatti, G.2
Fletcher, C.3
Garaffo, R.4
Haubrich, R.5
Hoetelmans, R.6
Kurowski, M.7
Luber, A.8
Merry, C.9
Perno, C.F.10
-
4
-
-
0142258774
-
Therapeutic drug monitoring in the treatment of HIV-infection
-
10.1016/S1386-6532(03)00033-7 12829033
-
Gerber JG Acosta EP Therapeutic drug monitoring in the treatment of HIV-infection J Clin Virol 2003, 27:117-128 10.1016/ S1386-6532(03)00033-7 12829033
-
(2003)
J Clin Virol
, vol.27
, pp. 117-128
-
-
Gerber, J.G.1
Acosta, E.P.2
-
5
-
-
0035866329
-
A luciferase-reporter gene-expressing T-cell line facilitates neutralization and drug-sensitivity assays that use either R5 or X4 strains of human immunodeficiency virus type 1
-
10.1006/viro.2000.0780 11162843
-
Spenlehauer C Gordon CA Trkola A Moore JP A luciferase-reporter gene-expressing T-cell line facilitates neutralization and drug-sensitivity assays that use either R5 or X4 strains of human immunodeficiency virus type 1 Virology 2001, 280:292-300 10.1006/ viro.2000.0780 11162843
-
(2001)
Virology
, vol.280
, pp. 292-300
-
-
Spenlehauer, C.1
Gordon, C.A.2
Trkola, A.3
Moore, J.P.4
-
6
-
-
0035144979
-
Rapid and simple phenotypic assay for drug susceptibility of human immunodeficiency virus type 1 using CCR5-expressing HeLa/CD4(+) cell clone 1-10 (MAGIC-5)
-
90318 11158746 10.1128/AAC.45.2.495-501.2001
-
Hachiya A Aizawa-Matsuoka S Tanaka M Takahashi Y Ida S Gatanaga H Hirabayashi Y Kojima A Tasumi M Oka S Rapid and simple phenotypic assay for drug susceptibility of human immunodeficiency virus type 1 using CCR5-expressing HeLa/CD4(+) cell clone 1-10 (MAGIC-5) Antimicrob Agents Chemother 2001, 45:495-501 90318 11158746 10.1128/AAC.45.2.495-501.2001
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 495-501
-
-
Hachiya, A.1
Aizawa-Matsuoka, S.2
Tanaka, M.3
Takahashi, Y.4
Ida, S.5
Gatanaga, H.6
Hirabayashi, Y.7
Kojima, A.8
Tasumi, M.9
Oka, S.10
-
7
-
-
0030935663
-
A new reporter cell line to monitor HIV infection and drug susceptibility in vitro
-
20779 9114046 10.1073/pnas.94.9.4653
-
Gervaix A West D Leoni LM Richman DD Wong-Staal F Corbeil J A new reporter cell line to monitor HIV infection and drug susceptibility in vitro Proc Natl Acad Sci USA 1997, 94:4653-4658 20779 9114046 10.1073/ pnas.94.9.4653
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4653-4658
-
-
Gervaix, A.1
West, D.2
Leoni, L.M.3
Richman, D.D.4
Wong-Staal, F.5
Corbeil, J.6
-
8
-
-
33847064207
-
Use of new T-cell-based cell lines expressing two luciferase reporters for accurately evaluating susceptibility to anti-human immunodeficiency virus type 1 drugs
-
10.1128/JCM.01708-06
-
Chiba-Mizutani T Miura H Matsuda M Matsuda Z Yokomaku Y Miyauchi K Nishizawa M Yamamoto N Sugiura W Use of new T-cell-based cell lines expressing two luciferase reporters for accurately evaluating susceptibility to anti-human immunodeficiency virus type 1 drugs J Clin Microbiol 2007, 45:477-487 1829063 17182760 10.1128/JCM.01708-06
-
(2007)
J Clin Microbiol
, vol.45
, pp. 477-487
-
-
Chiba-Mizutani, T.1
Miura, H.2
Matsuda, M.3
Matsuda, Z.4
Yokomaku, Y.5
Miyauchi, K.6
Nishizawa, M.7
Yamamoto, N.8
Sugiura, W.9
-
9
-
-
0035252382
-
Viral dynamics and anti-viral pharmacodynamics: Rethinking in vitro measures of drug potency
-
10.1016/S0165-6147(00)01615-1 11166854
-
Ferguson NM Fraser C Anderson RM Viral dynamics and anti-viral pharmacodynamics: Rethinking in vitro measures of drug potency Trends Pharmacol Sci 2001, 22:97-100 10.1016/S0165-6147(00)01615-1 11166854
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 97-100
-
-
Ferguson, N.M.1
Fraser, C.2
Anderson, R.M.3
-
10
-
-
46049096485
-
Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs
-
10.1038/nm1777 18552857
-
Shen L Peterson S Sedaghat AR McMahon MA Callender M Zhang H Zhou Y Pitt E Anderson KS Acosta EP Siliciano RF Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs Nat Med 2008, 14:762-766 10.1038/nm1777 18552857
-
(2008)
Nat Med
, vol.14
, pp. 762-766
-
-
Shen, L.1
Peterson, S.2
Sedaghat, A.R.3
McMahon, M.A.4
Callender, M.5
Zhang, H.6
Zhou, Y.7
Pitt, E.8
Anderson, K.S.9
Acosta, E.P.10
Siliciano, R.F.11
-
11
-
-
35848929439
-
Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2′,3′-didehydro-3′-deoxy-4′-ethynylthymidine, a novel thymidine analog
-
2151449 17724147 10.1128/AAC.00692-07
-
Paintsil E Dutschman GE Hu R Grill SP Lam W Baba M Tanaka H Cheng YC Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2′,3′-didehydro-3′-deoxy-4′-ethynylthymidine, a novel thymidine analog Antimicrob Agents Chemother 2007, 51:3870-3879 2151449 17724147 10.1128/AAC.00692-07
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 3870-3879
-
-
Paintsil, E.1
Dutschman, G.E.2
Hu, R.3
Grill, S.P.4
Lam, W.5
Baba, M.6
Tanaka, H.7
Cheng, Y.C.8
-
12
-
-
0036090585
-
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy
-
127242 12019106 10.1128/AAC.46.6.1896-1905.2002
-
Wei X Decker JM Liu H Zhang Z Arani RB Kilby JM Saag MS Wu X Shaw GM Kappes JC Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy Antimicrob Agents Chemother 2002, 46:1896-1905 127242 12019106 10.1128/ AAC.46.6.1896-1905.2002
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 1896-1905
-
-
Wei, X.1
Decker, J.M.2
Liu, H.3
Zhang, Z.4
Arani, R.B.5
Kilby, J.M.6
Saag, M.S.7
Wu, X.8
Shaw, G.M.9
Kappes, J.C.10
-
13
-
-
2142713068
-
4′-substituted stavudine analog with improved anti-human immunodeficiency virus activity and decreased cytotoxicity
-
400579 15105115 10.1128/AAC.48.5.1640-1646.2004
-
Dutschman GE Grill SP Gullen EA Haraguchi K Takeda S Tanaka H Baba M Cheng YC Novel 4′-substituted stavudine analog with improved anti-human immunodeficiency virus activity and decreased cytotoxicity Antimicrob Agents Chemother 2004, 48:1640-1646 400579 15105115 10.1128/ AAC.48.5.1640-1646.2004
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 1640-1646
-
-
Dutschman, G.E.1
Grill, S.P.2
Gullen, E.A.3
Haraguchi, K.4
Takeda, S.5
Tanaka, H.6
Baba, M.7
Cheng, Y.C.8
-
14
-
-
0141545085
-
Synthesis of a highly active new anti-HIV agent 2′,3′-didehydro-3′-deoxy-4′-ethynylthymidine
-
10.1016/j.bmcl.2003.07.009 14552777
-
Haraguchi K Takeda S Tanaka H Nitanda T Baba M Dutschman GE Cheng YC Synthesis of a highly active new anti-HIV agent 2′,3′-didehydro-3′-deoxy-4′-ethynylthymidine Bioorg Med Chem Lett 2003, 13:3775-3777 10.1016/j.bmcl.2003.07.009 14552777
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 3775-3777
-
-
Haraguchi, K.1
Takeda, S.2
Tanaka, H.3
Nitanda, T.4
Baba, M.5
Dutschman, G.E.6
Cheng, Y.C.7
-
15
-
-
33749401364
-
Inhibition of HIV-1 replication by amphotericin B methyl ester: Selection for resistant variants
-
10.1074/jbc.M603609200 16882663
-
Waheed AA Ablan SD Mankowski MK Cummins JE Ptak RG Schaffner CP Freed EO Inhibition of HIV-1 replication by amphotericin B methyl ester: selection for resistant variants J Biol Chem 2006, 281:28699-28711 10.1074/jbc.M603609200 16882663
-
(2006)
J Biol Chem
, vol.281
, pp. 28699-28711
-
-
Waheed, A.A.1
Ablan, S.D.2
Mankowski, M.K.3
Cummins, J.E.4
Ptak, R.G.5
Schaffner, C.P.6
Freed, E.O.7
-
16
-
-
0029881506
-
Design and synthesis of (beta-L-d4C) and 2′,3′-dideoxy 2′,3′-didehydro-beta-L-5-fluorocytidine (beta-L-Fd4C), two exceptionally potent inhibitors of human hepatitis B virus (HBV) and potent inhibitors of human immunodeficiency virus (HIV) in vitro
-
10.1021/jm950836q 8627596
-
Lin TS Luo MZ Liu MC Zhu YL Gullen E Dutschman GE Cheng YC Design and synthesis of 2′,3′-dideoxy-2′,3′-didehydro- beta-L-cytidine (beta-L-d4C) and 2′,3′-dideoxy 2′,3′-didehydro-beta-L-5-fluorocytidine (beta-L-Fd4C), two exceptionally potent inhibitors of human hepatitis B virus (HBV) and potent inhibitors of human immunodeficiency virus (HIV) in vitro J Med Chem 1996, 39:1757-1759 10.1021/jm950836q 8627596
-
(1996)
J Med Chem
, vol.39
, pp. 1757-1759
-
-
Lin, T.S.1
Luo, M.Z.2
Liu, M.C.3
Zhu, Y.L.4
Gullen, E.5
Dutschman, G.E.6
Cheng, Y.C.7
-
17
-
-
0031836316
-
Metabolism of 2′,3′-dideoxy-2′,3′-didehydro-beta- L(-)-5-fluorocytidine and its activity in combination with clinically approved anti-human immunodeficiency virus beta-D(+) nucleoside analogs in vitro
-
Dutschman GE Bridges EG Liu SH Gullen E Guo X Kukhanova M Cheng YC Metabolism of 2′,3′-dideoxy-2′,3′-didehydro-beta- L(-)-5-fluorocytidine and its activity in combination with clinically approved anti-human immunodeficiency virus beta-D(+) nucleoside analogs in vitro. Antimicrob Agents Chemother 1998, 42:1799-1804
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 1799-1804
-
-
Dutschman, G.E.1
Bridges, E.G.2
Liu, S.H.3
Gullen, E.4
Guo, X.5
Kukhanova, M.6
Cheng, Y.C.7
-
18
-
-
0029965190
-
Favorable interaction of beta-L(-) nucleoside analogues with clinically approved anti-HIV nucleoside analogues for the treatment of human immunodeficiency virus
-
10.1016/0006-2952(96)00056-1 8602867
-
Bridges EG Dutschman GE Gullen EA Cheng YC Favorable interaction of beta-L(-) nucleoside analogues with clinically approved anti-HIV nucleoside analogues for the treatment of human immunodeficiency virus Biochem Pharmacol 1996, 51:731-736 10.1016/0006-2952(96)00056-1 8602867
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 731-736
-
-
Bridges, E.G.1
Dutschman, G.E.2
Gullen, E.A.3
Cheng, Y.C.4
-
19
-
-
0034212517
-
In vitro evaluation of the effect of temporary removal of HIV drug pressure
-
10.1016/S0166-3542(00)00084-X 10867159
-
Witvrouw M Pannecouque C Desmyter J De Clercq E Andries K In vitro evaluation of the effect of temporary removal of HIV drug pressure Antiviral Res 2000, 46:215-221 10.1016/S0166-3542(00)00084-X 10867159
-
(2000)
Antiviral Res
, vol.46
, pp. 215-221
-
-
Witvrouw, M.1
Pannecouque, C.2
Desmyter, J.3
De Clercq, E.4
Andries, K.5
-
20
-
-
0001024860
-
The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1
-
10.1097/00002030-199911120-00006 10563709
-
Moore KH Barrett JE Shaw S Pakes GE Churchus R Kapoor A Lloyd J Barry MG Back D The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1 AIDS 1999, 13:2239-2250 10.1097/00002030-199911120-00006 10563709
-
(1999)
AIDS
, vol.13
, pp. 2239-2250
-
-
Moore, K.H.1
Barrett, J.E.2
Shaw, S.3
Pakes, G.E.4
Churchus, R.5
Kapoor, A.6
Lloyd, J.7
Barry, M.G.8
Back, D.9
-
21
-
-
39149108828
-
Decreased adherence to antiretroviral therapy observed prior to transient human immunodeficiency virus type 1 viremia
-
10.1086/523704 18190257
-
Podsadecki TJ Vrijens BC Tousset EP Rode RA Hanna GJ Decreased adherence to antiretroviral therapy observed prior to transient human immunodeficiency virus type 1 viremia J Infect Dis 2007, 196:1773-1778 10.1086/523704 18190257
-
(2007)
J Infect Dis
, vol.196
, pp. 1773-1778
-
-
Podsadecki, T.J.1
Vrijens, B.C.2
Tousset, E.P.3
Rode, R.A.4
Hanna, G.J.5
-
22
-
-
37349068523
-
Differential adherence to combination antiretroviral therapy is associated with virological failure with resistance
-
2405889 18090394 10.1097/QAD.0b013e3282f366ff
-
Gardner EM Sharma S Peng G Hullsiek KH Burman WJ Macarthur RD Chesney M Telzak EE Friedland G Mannheimer SB Differential adherence to combination antiretroviral therapy is associated with virological failure with resistance AIDS 2008, 22:75-82 2405889 18090394 10.1097/ QAD.0b013e3282f366ff
-
(2008)
AIDS
, vol.22
, pp. 75-82
-
-
Gardner, E.M.1
Sharma, S.2
Peng, G.3
Hullsiek, K.H.4
Burman, W.J.5
Macarthur, R.D.6
Chesney, M.7
Telzak, E.E.8
Friedland, G.9
Mannheimer, S.B.10
-
23
-
-
0028205185
-
Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives
-
10.1007/BF01880662 8032337
-
Balzarini J Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives Pharm World Sci 1994, 16:113-126 10.1007/ BF01880662 8032337
-
(1994)
Pharm World Sci
, vol.16
, pp. 113-126
-
-
Balzarini, J.1
-
24
-
-
0027976787
-
Restriction and enhancement of human immunodeficiency virus type 1 replication by modulation of intracellular deoxynucleoside triphosphate pools
-
236318 8254768
-
Meyerhans A Vartanian JP Hultgren C Plikat U Karlsson A Wang L Erikson S Wain-Hobson S Restriction and enhancement of human immunodeficiency virus type 1 replication by modulation of intracellular deoxynucleoside triphosphate pools J Virol 1994, 68:535-540 236318 8254768
-
(1994)
J Virol
, vol.68
, pp. 535-540
-
-
Meyerhans, A.1
Vartanian, J.P.2
Hultgren, C.3
Plikat, U.4
Karlsson, A.5
Wang, L.6
Erikson, S.7
Wain-Hobson, S.8
-
25
-
-
0029757751
-
Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme
-
452124 8670908
-
Back NK Nijhuis M Keulen W Boucher CA Oude Essink BO van Kuilenburg AB van Gennip AH Berkhout B Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme Embo J 1996, 15:4040-4049 452124 8670908
-
(1996)
Embo J
, vol.15
, pp. 4040-4049
-
-
Back, N.K.1
Nijhuis, M.2
Keulen, W.3
Boucher, C.A.4
Oude Essink, B.O.5
van Kuilenburg, A.B.6
van Gennip, A.H.7
Berkhout, B.8
-
26
-
-
0242333229
-
Antiviral dynamics and sex differences of zidovudine and lamivudine triphosphate concentrations in HIV-infected individuals
-
10.1097/00002030-200310170-00003 14523272
-
Anderson PL Kakuda TN Kawle S Fletcher CV Antiviral dynamics and sex differences of zidovudine and lamivudine triphosphate concentrations in HIV-infected individuals AIDS 2003, 17:2159-2168 10.1097/ 00002030-200310170-00003 14523272
-
(2003)
AIDS
, vol.17
, pp. 2159-2168
-
-
Anderson, P.L.1
Kakuda, T.N.2
Kawle, S.3
Fletcher, C.V.4
-
27
-
-
0032870854
-
Drug Monitoring of Antiretroviral Therapy for HIV-1 Infection: Method Validation and Results of a Pilot Study
-
10471649
-
Moyer TP Temesgen Z Enger R Estes L Charlson J Oliver L Wright A Drug Monitoring of Antiretroviral Therapy for HIV-1 Infection: Method Validation and Results of a Pilot Study Clin Chem 1999, 45:1465-1476 10471649
-
(1999)
Clin Chem
, vol.45
, pp. 1465-1476
-
-
Moyer, T.P.1
Temesgen, Z.2
Enger, R.3
Estes, L.4
Charlson, J.5
Oliver, L.6
Wright, A.7
-
28
-
-
33747100570
-
Pharmacology of current and promising nucleosides for the treatment of human immunodeficiency viruses
-
10.1016/j.antiviral.2006.03.012 16716415
-
Schinazi RF Hernandez-Santiago BI Hurwitz SJ Pharmacology of current and promising nucleosides for the treatment of human immunodeficiency viruses Antiviral Res 2006, 71:322-334 10.1016/j.antiviral.2006.03.012 16716415
-
(2006)
Antiviral Res
, vol.71
, pp. 322-334
-
-
Schinazi, R.F.1
Hernandez-Santiago, B.I.2
Hurwitz, S.J.3
-
29
-
-
66349099708
-
A Single Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of OBP-601 (4;-Ed4Ta Novel NRTI) in Healthy Subjects
-
Montreal, Canada
-
Mastuda T Paintsil E Ross JS Schofield J Cheng YC Urata Y A Single Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of OBP-601 (4;-Ed4Ta Novel NRTI) in Healthy Subjects 16th Conference on Retroviruses and Opportunistic Infections. Montreal, Canada 2009
-
(2009)
16th Conference on Retroviruses and Opportunistic Infections
-
-
Mastuda, T.1
Paintsil, E.2
Ross, J.S.3
Schofield, J.4
Cheng, Y.C.5
Urata, Y.6
-
30
-
-
34848886926
-
Intracellular nucleoside triphosphate concentrations in HIV-infected patients on dual nucleoside reverse transcriptase inhibitor therapy
-
17926654
-
Moore JD Acosta EP Johnson VA Bassett R Eron JJ Fischl MA Long MC Kuritzkes DR Sommadossi JP Intracellular nucleoside triphosphate concentrations in HIV-infected patients on dual nucleoside reverse transcriptase inhibitor therapy Antivir Ther 2007, 12:981-986 17926654
-
(2007)
Antivir Ther
, vol.12
, pp. 981-986
-
-
Moore, J.D.1
Acosta, E.P.2
Johnson, V.A.3
Bassett, R.4
Eron, J.J.5
Fischl, M.A.6
Long, M.C.7
Kuritzkes, D.R.8
Sommadossi, J.P.9
-
31
-
-
22344455482
-
Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens
-
10.1097/01.qai.0000167155.44980.e8 16010161
-
Hawkins T Veikley W St Claire RL 3rd Guyer B Clark N Kearney BP Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens J Acquir Immune Defic Syndr 2005, 39:406-411 10.1097/01.qai.0000167155.44980.e8 16010161
-
(2005)
J Acquir Immune Defic Syndr
, vol.39
, pp. 406-411
-
-
Hawkins, T.1
Veikley, W.2
St Claire III, R.L.3
Guyer, B.4
Clark, N.5
Kearney, B.P.6
-
32
-
-
0023258934
-
3′-azido-3′-deoxythymidine. An unusual nucleoside analogue that permeates the membrane of human erythrocytes and lymphocytes by nonfacilitated diffusion
-
3471758
-
Zimmerman TP Mahony WB Prus KL 3′-azido-3′-deoxythymidine. An unusual nucleoside analogue that permeates the membrane of human erythrocytes and lymphocytes by nonfacilitated diffusion J Biol Chem 1987, 262:5748-5754 3471758
-
(1987)
J Biol Chem
, vol.262
, pp. 5748-5754
-
-
Zimmerman, T.P.1
Mahony, W.B.2
Prus, K.L.3
-
33
-
-
19644399336
-
Incidence of pancreatitis in HIV-1-infected individuals enrolled in 20 adult AIDS clinical trials group studies: Lessons learned
-
1373674 15905731
-
Reisler RB Murphy RL Redfield RR Parker RA Incidence of pancreatitis in HIV-1-infected individuals enrolled in 20 adult AIDS clinical trials group studies: Lessons learned J Acquir Immune Defic Syndr 2005, 39:159-166 1373674 15905731
-
(2005)
J Acquir Immune Defic Syndr
, vol.39
, pp. 159-166
-
-
Reisler, R.B.1
Murphy, R.L.2
Redfield, R.R.3
Parker, R.A.4
-
34
-
-
0031979775
-
Effectiveness of postinoculation (R)-9-(2-phosphonylmethoxypropyl) adenine treatment for prevention of persistent simian immunodeficiency virus SIVmne infection depends critically on timing of initiation and duration of treatment
-
109656 9557716
-
Tsai CC Emau P Follis KE Beck TW Benveniste RE Bischofberger N Lifson JD Morton WR Effectiveness of postinoculation (R)-9-(2-phosphonylmethoxypropyl) adenine treatment for prevention of persistent simian immunodeficiency virus SIVmne infection depends critically on timing of initiation and duration of treatment J Virol 1998, 72:4265-4273 109656 9557716
-
(1998)
J Virol
, vol.72
, pp. 4265-4273
-
-
Tsai, C.C.1
Emau, P.2
Follis, K.E.3
Beck, T.W.4
Benveniste, R.E.5
Bischofberger, N.6
Lifson, J.D.7
Morton, W.R.8
-
35
-
-
0031029005
-
Prevention of simian immunodeficiency virus, SIVsm, or HIV-2 infection in cynomolgus monkeys by pre- and postexposure administration of BEA-005
-
10.1097/00002030-199702000-00004 9030361
-
Bottiger D Johansson NG Samuelsson B Zhang H Putkonen P Vrang L Oberg B Prevention of simian immunodeficiency virus, SIVsm, or HIV-2 infection in cynomolgus monkeys by pre- and postexposure administration of BEA-005 AIDS 1997, 11:157-162 10.1097/00002030-199702000-00004 9030361
-
(1997)
AIDS
, vol.11
, pp. 157-162
-
-
Bottiger, D.1
Johansson, N.G.2
Samuelsson, B.3
Zhang, H.4
Putkonen, P.5
Vrang, L.6
Oberg, B.7
-
36
-
-
13744249434
-
Antiretroviral postexposure prophylaxis after sexual, injection-drug use, or other nonoccupational exposure to HIV in the United States: Recommendations from the U.S. Department of Health and Human Services
-
15660015
-
Smith DK Grohskopf LA Black RJ Auerbach JD Veronese F Struble KA Cheever L Johnson M Paxton LA Onorato IM Greenberg AE Antiretroviral postexposure prophylaxis after sexual, injection-drug use, or other nonoccupational exposure to HIV in the United States: Recommendations from the U.S. Department of Health and Human Services MMWR Recomm Rep 2005, 54:1-20 15660015
-
(2005)
MMWR Recomm Rep
, vol.54
, pp. 1-20
-
-
Smith, D.K.1
Grohskopf, L.A.2
Black, R.J.3
Auerbach, J.D.4
Veronese, F.5
Struble, K.A.6
Cheever, L.7
Johnson, M.8
Paxton, L.A.9
Onorato, I.M.10
Greenberg, A.E.11
-
37
-
-
50949097030
-
Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel
-
2494562 18684007 10.1371/journal.pmed.0050157
-
Cranage M Sharpe S Herrera C Cope A Dennis M Berry N Ham C Heeney J Rezk N Kashuba A Anton P McGowan I Shattock R Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel PLoS Med 2008, 5:e157 2494562 18684007 10.1371/journal.pmed.0050157
-
(2008)
PLoS Med
, vol.5
-
-
Cranage, M.1
Sharpe, S.2
Herrera, C.3
Cope, A.4
Dennis, M.5
Berry, N.6
Ham, C.7
Heeney, J.8
Rezk, N.9
Kashuba, A.10
Anton, P.11
McGowan, I.12
Shattock, R.13
-
38
-
-
34548267289
-
Antiretroviral drug exposure in the female genital tract: Implications for oral pre- and post-exposure prophylaxis
-
10.1097/QAD.0b013e328270385a 17721097
-
Dumond JB Yeh RF Patterson KB Corbett AH Jung BH Rezk NL Bridges AS Stewart PW Cohen MS Kashuba AD Antiretroviral drug exposure in the female genital tract: Implications for oral pre- and post-exposure prophylaxis AIDS 2007, 21:1899-1907 10.1097/QAD.0b013e328270385a 17721097
-
(2007)
AIDS
, vol.21
, pp. 1899-1907
-
-
Dumond, J.B.1
Yeh, R.F.2
Patterson, K.B.3
Corbett, A.H.4
Jung, B.H.5
Rezk, N.L.6
Bridges, A.S.7
Stewart, P.W.8
Cohen, M.S.9
Kashuba, A.D.10
-
39
-
-
36049039178
-
Single-dose tenofovir and emtricitabine for reduction of viral resistance to non-nucleoside reverse transcriptase inhibitor drugs in women given intrapartum nevirapine for perinatal HIV prevention: An open-label randomised trial
-
10.1016/S0140-6736(07)61605-5 17997151
-
Chi BH Sinkala M Mbewe F Cantrell RA Kruse G Chintu N Aldrovandi GM Stringer EM Kankasa C Safrit JT Stringer JS Single-dose tenofovir and emtricitabine for reduction of viral resistance to non-nucleoside reverse transcriptase inhibitor drugs in women given intrapartum nevirapine for perinatal HIV prevention: An open-label randomised trial Lancet 2007, 370:1698-1705 10.1016/S0140-6736(07)61605-5 17997151
-
(2007)
Lancet
, vol.370
, pp. 1698-1705
-
-
Chi, B.H.1
Sinkala, M.2
Mbewe, F.3
Cantrell, R.A.4
Kruse, G.5
Chintu, N.6
Aldrovandi, G.M.7
Stringer, E.M.8
Kankasa, C.9
Safrit, J.T.10
Stringer, J.S.11
-
40
-
-
0033966504
-
Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy
-
10.1038/71569 10613828
-
Sharkey ME Teo I Greenough T Sharova N Luzuriaga K Sullivan JL Bucy RP Kostrikis LG Haase A Veryard C Davaro RE Cheesman SH Daly JS Bova C Ellison RT 3rd Mady B Lai KK Moyle G Nelson M Gazzard B Shaunak S Stevenson M Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy Nat Med 2000, 6:76-81 10.1038/71569 10613828
-
(2000)
Nat Med
, vol.6
, pp. 76-81
-
-
Sharkey, M.E.1
Teo, I.2
Greenough, T.3
Sharova, N.4
Luzuriaga, K.5
Sullivan, J.L.6
Bucy, R.P.7
Kostrikis, L.G.8
Haase, A.9
Veryard, C.10
Davaro, R.E.11
Cheesman, S.H.12
Daly, J.S.13
Bova, C.14
Ellison III, R.T.15
Mady, B.16
Lai, K.K.17
Moyle, G.18
Nelson, M.19
Gazzard, B.20
Shaunak, S.21
Stevenson, M.22
more..
-
41
-
-
0033984045
-
The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy
-
10.1038/71577 10613829
-
Ramratnam B Mittler JE Zhang L Boden D Hurley A Fang F Macken CA Perelson AS Markowitz M Ho DD The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy Nat Med 2000, 6:82-85 10.1038/71577 10613829
-
(2000)
Nat Med
, vol.6
, pp. 82-85
-
-
Ramratnam, B.1
Mittler, J.E.2
Zhang, L.3
Boden, D.4
Hurley, A.5
Fang, F.6
Macken, C.A.7
Perelson, A.S.8
Markowitz, M.9
Ho, D.D.10
-
42
-
-
34547620353
-
Activity against human immunodeficiency virus type 1, intracellular metabolism, and effects on human DNA polymerases of 4′-ethynyl-2-fluoro-2′-deoxyadenosine
-
1932487 17548498 10.1128/AAC.00277-07
-
Nakata H Amano M Koh Y Kodama E Yang G Bailey CM Kohgo S Hayakawa H Matsuoka M Anderson KS Cheng YC Mitsuya H Activity against human immunodeficiency virus type 1, intracellular metabolism, and effects on human DNA polymerases of 4′-ethynyl-2-fluoro-2′-deoxyadenosine Antimicrob Agents Chemother 2007, 51:2701-2708 1932487 17548498 10.1128/AAC.00277-07
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 2701-2708
-
-
Nakata, H.1
Amano, M.2
Koh, Y.3
Kodama, E.4
Yang, G.5
Bailey, C.M.6
Kohgo, S.7
Hayakawa, H.8
Matsuoka, M.9
Anderson, K.S.10
Cheng, Y.C.11
Mitsuya, H.12
-
44
-
-
10644246071
-
Persistent antiretroviral activity of nucleoside analogues after prolonged zidovudine and lamivudine therapy as demonstrated by rapid loss of activity after discontinuation
-
10.1097/00126334-200412150-00009 15577413
-
Eron JJ Jr Bartlett JA Santana JL Bellos NC Johnson J Keller A Kuritzkes DR St Clair MH Johnson VA Persistent antiretroviral activity of nucleoside analogues after prolonged zidovudine and lamivudine therapy as demonstrated by rapid loss of activity after discontinuation J Acquir Immune Defic Syndr 2004, 37:1581-1583 10.1097/00126334-200412150-00009 15577413
-
(2004)
J Acquir Immune Defic Syndr
, vol.37
, pp. 1581-1583
-
-
Eron Jr., J.J.1
Bartlett, J.A.2
Santana, J.L.3
Bellos, N.C.4
Johnson, J.5
Keller, A.6
Kuritzkes, D.R.7
St Clair, M.H.8
Johnson, V.A.9
-
45
-
-
0027363224
-
Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus
-
10.1006/viro.1993.1513 7690501
-
Balzarini J Karlsson A Perez-Perez MJ Camarasa MJ De Clercq E Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus Virology 1993, 196:576-585 10.1006/viro.1993.1513 7690501
-
(1993)
Virology
, vol.196
, pp. 576-585
-
-
Balzarini, J.1
Karlsson, A.2
Perez-Perez, M.J.3
Camarasa, M.J.4
De Clercq, E.5
-
46
-
-
0029944278
-
Complete inhibition of viral breakthrough by combination of MKC-442 with AZT during a long-term culture of HIV-1 infected cells
-
10.1016/0166-3542(96)00946-1 8793010
-
Okamoto M Makino M Yamada K Nakade K Yuasa S Baba M Complete inhibition of viral breakthrough by combination of MKC-442 with AZT during a long-term culture of HIV-1 infected cells Antiviral Res 1996, 31:69-77 10.1016/0166-3542(96)00946-1 8793010
-
(1996)
Antiviral Res
, vol.31
, pp. 69-77
-
-
Okamoto, M.1
Makino, M.2
Yamada, K.3
Nakade, K.4
Yuasa, S.5
Baba, M.6
-
47
-
-
0027407285
-
Pharmacokinetics of nevirapine: Initial single-rising-dose study in humans
-
187634 8452345
-
Cheeseman SH Hattox SE McLaughlin MM Pharmacokinetics of nevirapine: initial single-rising-dose study in humans Antimicrob Agents Chemother 1993, 37:178-182 187634 8452345
-
(1993)
Antimicrob Agents Chemother
, vol.37
, pp. 178-182
-
-
Cheeseman, S.H.1
Hattox, S.E.2
McLaughlin, M.M.3
-
48
-
-
0035913939
-
Selection and fading of resistance mutations in women and infants receiving nevirapine to prevent HIV-1 vertical transmission (HIVNET 012)
-
10.1097/00002030-200110190-00006 11600822
-
Eshleman SH Mracna M Guay LA Deseyve M Cunningham S Mirochnick M Musoke P Fleming T Glenn Fowler M Mofenson LM Mmiro F Jackson JB Selection and fading of resistance mutations in women and infants receiving nevirapine to prevent HIV-1 vertical transmission (HIVNET 012) AIDS 2001, 15:1951-1957 10.1097/00002030-200110190-00006 11600822
-
(2001)
AIDS
, vol.15
, pp. 1951-1957
-
-
Eshleman, S.H.1
Mracna, M.2
Guay, L.A.3
Deseyve, M.4
Cunningham, S.5
Mirochnick, M.6
Musoke, P.7
Fleming, T.8
Glenn Fowler, M.9
Mofenson, L.M.10
Mmiro, F.11
Jackson, J.B.12
-
49
-
-
1642420304
-
Relationship between antiviral activity and host toxicity: Comparison of the incorporation efficiencies of 2′,3′-dideoxy-5-fluoro-3′-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase
-
375312 15047533 10.1128/AAC.48.4.1300-1306.2004
-
Feng JY Murakami E Zorca SM Johnson AA Johnson KA Schinazi RF Furman PA Anderson KS Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2′,3′-dideoxy-5-fluoro-3′-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase Antimicrob Agents Chemother 2004, 48:1300-1306 375312 15047533 10.1128/AAC.48.4.1300-1306.2004
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 1300-1306
-
-
Feng, J.Y.1
Murakami, E.2
Zorca, S.M.3
Johnson, A.A.4
Johnson, K.A.5
Schinazi, R.F.6
Furman, P.A.7
Anderson, K.S.8
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