Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus

Stem Cells

Volumn 24, Issue 9, 2006, Pages 2007-2013

  Blelloch, Robert ^a,b   Wang, Zhongde ^a   Meissner, Alex ^a   Pollard, Steven ^c   Smith, Austin ^c   Jaenisch, Rudolf ^a  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

DNA methylation; Embryonic stem cells; Nuclear transfer; Reprogramming

Indexed keywords

DNA METHYLTRANSFERASE 1; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLASTOCYST; CELL CLONING; CELL DIFFERENTIATION; CELL NUCLEUS TRANSPLANTATION; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; CORRELATION ANALYSIS; DONOR; EMBRYONIC STEM CELL; GENOMICS; METHYLATION; MOUSE; NEURAL STEM CELL; NONHUMAN; PLURIPOTENT STEM CELL; PROMOTER REGION; SOMATIC CELL;

ANIMALS; CELL DIFFERENTIATION; CELL NUCLEUS; CELLS, CULTURED; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA-BINDING PROTEINS; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; MICE; MICE, INBRED C57BL; NEURONS; OCTAMER TRANSCRIPTION FACTOR-3; PLURIPOTENT STEM CELLS; PROMOTER REGIONS (GENETICS); RESEARCH EMBRYO CREATION; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA;

ANIMALIA;

EID: 33745525505     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2006-0050     Document Type: Article

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