Enhancement of lung carcinogenesis initiated with 4-(N- hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone by Ogg1 gene deficiency in female, but not male, mice

Journal of Toxicological Sciences

Volumn 34, Issue 2, 2009, Pages 163-174

  Igarashi, Maki ^a,b,g   Watanabe, Manabu ^b   Yoshida, Midori ^c   Sugaya, Kouichi ^a   Endo, Yoshifumi ^d   Miyajima, Nozomi ^d   Abe, Masayoshi ^e   Sugano, Sumio ^b   Nakae, Dai ^a,f  

^a TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e NISSAN CHEMICAL INDUSTRIES LTD   (Japan)

^f TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

^g NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

4 (N Hydroxymethylnitrosamino) 1 (3 pyridyl) 1 butanone; 8 Oxoguanine; Egfr gene; Lung adeno carcinogenesis; Ogg1 gene deficient mouse; Oxidative stress

Indexed keywords

4-(N-HYDROXYMETHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE; 8 HYDROXYGUANINE; 8 HYDROXYGUANINE DNA GLYCOSYLASE 1; DNA GLYCOSYLTRANSFERASE; EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN; LACTOFERRIN; N TERT BUTYL ALPHA PHENYLNITRONE; NITROSAMINE; RESVERATROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENETIC ANALYSIS; LUNG ADENOCARCINOMA; LUNG ADENOMA; LUNG CARCINOGENESIS; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS;

ANIMALIA; MUS; VACCINIUM MYRTILLUS;

EID: 66149184556     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.34.163     Document Type: Article

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