-
1
-
-
0038381492
-
Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor
-
Bunger, M.K., Moran, S.M., Glover, E., Thomae, T.L., Lahvis, G.P., Lin, B.C. and Bradfield, C.A. (2003): Resistance to 2,3,7,8-tetrachlorodibenzo-p- dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor. J. Biol. Chem., 278, 17767-17774.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17767-17774
-
-
Bunger, M.K.1
Moran, S.M.2
Glover, E.3
Thomae, T.L.4
Lahvis, G.P.5
Lin, B.C.6
Bradfield, C.A.7
-
2
-
-
0027330053
-
Ultrastructure of the cortical epithelium of the rat thymus after in vivo exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
-
De Waal, E.J., Rademakers, L.H., Schuurman, H.J., Van Loveren, H. and Vos, J.G. (1993): Ultrastructure of the cortical epithelium of the rat thymus after in vivo exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Arch. Toxicol., 67, 558-564.
-
(1993)
Arch. Toxicol.
, vol.67
, pp. 558-564
-
-
De Waal, E.J.1
Rademakers, L.H.2
Schuurman, H.J.3
Van Loveren, H.4
Vos, J.G.5
-
3
-
-
0026770124
-
Alterations in the cortical thymic epithelium of rats after in vivo exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): An (immuno)histological study
-
De Waal, E.J., Schuurman, H.J., Loeber, J.G., Van Loveren, H. and Vos, J.G. (1992): Alterations in the cortical thymic epithelium of rats after in vivo exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): an (immuno)histological study. Toxicol. Appl. Pharmacol., 115, 80-88.
-
(1992)
Toxicol. Appl. Pharmacol.
, vol.115
, pp. 80-88
-
-
De Waal, E.J.1
Schuurman, H.J.2
Loeber, J.G.3
Van Loveren, H.4
Vos, J.G.5
-
4
-
-
0028034621
-
Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors
-
Ema, M., Ohe, N., Suzuki, M., Mimura, J., Sogawa, K., Ikawa, S. and Fujii-Kuriyama, Y. (1994): Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors. J. Biol. Chem., 269, 27337-27343.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 27337-27343
-
-
Ema, M.1
Ohe, N.2
Suzuki, M.3
Mimura, J.4
Sogawa, K.5
Ikawa, S.6
Fujii-Kuriyama, Y.7
-
5
-
-
0030245635
-
Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity
-
Fernandez-Salguero, P.M., Hilbert, D.M., Rudikoff, S., Ward, J.M. and Gonzalez, F.J. (1996): Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity. Toxicol. Appl. Pharmacol., 140, 173-179.
-
(1996)
Toxicol. Appl. Pharmacol.
, vol.140
, pp. 173-179
-
-
Fernandez-Salguero, P.M.1
Hilbert, D.M.2
Rudikoff, S.3
Ward, J.M.4
Gonzalez, F.J.5
-
6
-
-
2442745398
-
A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: Its possible translocation to nucleus
-
DOI 10.1073/pnas.85.16.5859
-
Fujisawa-Sehara, A., Yamane, M. and Fujii-Kuriyama, Y. (1988): A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus. Proc. Natl. Acad. Sci. USA, 85, 5859-5863. (Pubitemid 18209041)
-
(1988)
Proceedings of the National Academy of Sciences of the United States of America
, vol.85
, Issue.16
, pp. 5859-5863
-
-
Fujisawa-Sehara, A.1
Yamane, M.2
Fujii-Kuriyama, Y.3
-
7
-
-
66149187608
-
-
GALAS website 1
-
GALAS website 1: http://www.galas.org/about-galas.htm
-
-
-
-
8
-
-
66149159727
-
-
GALAS website 2
-
GALAS website 2: http://www.galas.org/WH-data.htm#growth
-
-
-
-
9
-
-
0032575589
-
A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle
-
Ge, N.L. and Elferink, C.J. (1998): A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle. J. Biol. Chem., 273, 22708-22713.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22708-22713
-
-
Ge, N.L.1
Elferink, C.J.2
-
10
-
-
0021816036
-
Evidence for direct action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on thymic epithelium
-
Greenlee, W.F., Dold, K.M., Irons, R.D. and Osborne, R. (1985): Evidence for direct action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on thymic epithelium. Toxicol. Appl. Pharmacol., 79, 112-120.
-
(1985)
Toxicol. Appl. Pharmacol.
, vol.79
, pp. 112-120
-
-
Greenlee, W.F.1
Dold, K.M.2
Irons, R.D.3
Osborne, R.4
-
11
-
-
2942616516
-
A constitutively active aryl-hydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest
-
Ito, T., Tsukumo, S., Suzuki, N., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y., Mimura, J., Lin, T.M., Peterson, R.E., Tohyama, C. and Nohara, K. (2004): A constitutively active aryl-hydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest. J. Biol. Chem., 279, 25204-25210.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25204-25210
-
-
Ito, T.1
Tsukumo, S.2
Suzuki, N.3
Motohashi, H.4
Yamamoto, M.5
Fujii-Kuriyama, Y.6
Mimura, J.7
Lin, T.M.8
Peterson, R.E.9
Tohyama, C.10
Nohara, K.11
-
12
-
-
0031062290
-
Evidence for the induction of apoptosis in thymocytes by 2,3,7,8- Tetrachlorodibenzo-p-dioxin in vivo
-
DOI 10.1006/taap.1996.8049
-
Kamath, A.B., Xu, H., Nagarkatti, P.S. and Nagarkatti, M. (1997): Evidence for the induction of apoptosis in thymocytes by 2,3,7,8- tetrachlorodibenzo-p-dioxin in vivo. Toxicol. Appl. Pharmacol., 142, 367-377. (Pubitemid 28381028)
-
(1997)
Toxicology and Applied Pharmacology
, vol.142
, Issue.2
, pp. 367-377
-
-
Kamath, A.B.1
Xu, H.2
Nagarkatti, P.S.3
Nagarkatti, M.4
-
13
-
-
33646150439
-
Differential susceptibilities of Holtzman and Sprague-Dawley rats to fetal death and placental dysfunction induced by 2,3,7,8-teterachlorodibenzo-p- dioxin (TCDD) despite the identical primary structure of the aryl hydrocarbon receptor
-
Kawakami, T., Ishimura, R., Nohara, K., Takeda, K., Tohyama, C. and Ohsako, S. (2006): Differential susceptibilities of Holtzman and Sprague-Dawley rats to fetal death and placental dysfunction induced by 2,3,7,8- teterachlorodibenzo-p-dioxin (TCDD) despite the identical primary structure of the aryl hydrocarbon receptor. Toxicol. Appl. Pharmacol., 212, 224-236.
-
(2006)
Toxicol. Appl. Pharmacol.
, vol.212
, pp. 224-236
-
-
Kawakami, T.1
Ishimura, R.2
Nohara, K.3
Takeda, K.4
Tohyama, C.5
Ohsako, S.6
-
14
-
-
0028031257
-
Thymic stroma exposed to arylhydrocarbon receptor-binding xenobiotics fails to support proliferation of early thymocytes but induces differentiation
-
Kremer, J., Gleichmann, E. and Esser, C. (1994): Thymic stroma exposed to arylhydrocarbon receptor-binding xenobiotics fails to support proliferation of early thymocytes but induces differentiation. J. Immunol., 153, 2778-2786.
-
(1994)
J. Immunol.
, vol.153
, pp. 2778-2786
-
-
Kremer, J.1
Gleichmann, E.2
Esser, C.3
-
15
-
-
0142179992
-
Cell proliferation arrest within intrathymic lymphocyte progenitor cells causes thymic atrophy mediated by the aryl hydrocarbon receptor
-
Laiosa, M.D., Wyman, A., Murante, F.G., Fiore, N.C., Staples, J.E., Gasiewicz, T.A. and Silverstone, A.E. (2003): Cell proliferation arrest within intrathymic lymphocyte progenitor cells causes thymic atrophy mediated by the aryl hydrocarbon receptor. J. Immunol., 171, 4582-4591.
-
(2003)
J. Immunol.
, vol.171
, pp. 4582-4591
-
-
Laiosa, M.D.1
Wyman, A.2
Murante, F.G.3
Fiore, N.C.4
Staples, J.E.5
Gasiewicz, T.A.6
Silverstone, A.E.7
-
16
-
-
0032899367
-
Identification of a novel mechanism of regulation of Ah (dioxin) receptor function
-
Mimura, J., Ema, M., Sogawa, K. and Fujii-Kuriyama, Y. (1999): Identification of a novel mechanism of regulation of Ah (dioxin) receptor function. Genes Dev., 13, 20-25.
-
(1999)
Genes Dev.
, vol.13
, pp. 20-25
-
-
Mimura, J.1
Ema, M.2
Sogawa, K.3
Fujii-Kuriyama, Y.4
-
17
-
-
34748878229
-
Aryl hydrocarbon receptor splice variants in the dioxin-resistant rat: Tissue expression and transactivational activity
-
Moffat, I.D., Roblin, S., Harper, P.A., Okey, A.B. and Pohjanvirta, R. (2007): Aryl hydrocarbon receptor splice variants in the dioxin-resistant rat: tissue expression and transactivational activity. Mol. Pharmacol., 72, 956-966.
-
(2007)
Mol. Pharmacol.
, vol.72
, pp. 956-966
-
-
Moffat, I.D.1
Roblin, S.2
Harper, P.A.3
Okey, A.B.4
Pohjanvirta, R.5
-
18
-
-
0037610805
-
Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse
-
Moriguchi, T., Motohashi, H., Hosoya, T., Nakajima, O., Takahashi, S., Ohsako, S., Aoki, Y., Nishimura, N., Tohyama, C., Fujii-Kuriyama, Y. and Yamamoto, M. (2003): Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse. Proc. Natl. Acad. Sci. USA, 100, 5652-5657.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5652-5657
-
-
Moriguchi, T.1
Motohashi, H.2
Hosoya, T.3
Nakajima, O.4
Takahashi, S.5
Ohsako, S.6
Aoki, Y.7
Nishimura, N.8
Tohyama, C.9
Fujii-Kuriyama, Y.10
Yamamoto, M.11
-
19
-
-
20044391611
-
Constitutively active aryl hydrocarbon receptor expressed specifically in T-lineage cells causes thymus involution and suppresses the immunization-induced increase in splenocytes
-
Nohara, K., Pan, X., Tsukumo, S., Hida, A., Ito, T., Nagai, H., Inouye, K., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y. and Tohyama, C. (2005): Constitutively active aryl hydrocarbon receptor expressed specifically in T-lineage cells causes thymus involution and suppresses the immunization-induced increase in splenocytes. J. Immunol., 174, 2770-2777.
-
(2005)
J. Immunol.
, vol.174
, pp. 2770-2777
-
-
Nohara, K.1
Pan, X.2
Tsukumo, S.3
Hida, A.4
Ito, T.5
Nagai, H.6
Inouye, K.7
Motohashi, H.8
Yamamoto, M.9
Fujii-Kuriyama, Y.10
Tohyama, C.11
-
20
-
-
34447530842
-
An aryl hydrocarbon receptor odyssey to the shores of toxicology: The Deichmann Lecture, International Congress of Toxicology-XI
-
DOI 10.1093/toxsci/kfm096
-
Okey, A.B. (2007): An aryl hydrocarbon receptor odyssey to the shores of toxicology: the Deichmann Lecture, International Congress of Toxicology-XI. Toxicol. Sci., 98, 5-38. (Pubitemid 47078751)
-
(2007)
Toxicological Sciences
, vol.98
, Issue.1
, pp. 5-38
-
-
Okey, A.B.1
-
21
-
-
0028588925
-
Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals: Effects, mechanisms, and animal models
-
Pohjanvirta, R. and Tuomisto, J. (1994): Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms, and animal models. Pharmacol. Rev., 46, 483-549.
-
(1994)
Pharmacol. Rev.
, vol.46
, pp. 483-549
-
-
Pohjanvirta, R.1
Tuomisto, J.2
-
22
-
-
0027257203
-
Comparative acute lethality of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 1,2,3,7,8-pentachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo- p-dioxin in the most TCDD-susceptible and the most TCDD-resistant rat strain
-
Pohjanvirta, R., Unkila, M. and Tuomisto, J. (1993): Comparative acute lethality of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 1,2,3,7,8- pentachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in the most TCDD-susceptible and the most TCDD-resistant rat strain. Pharmacol. Toxicol., 73, 52-56.
-
(1993)
Pharmacol. Toxicol.
, vol.73
, pp. 52-56
-
-
Pohjanvirta, R.1
Unkila, M.2
Tuomisto, J.3
-
23
-
-
0031845222
-
Point mutation in intron sequence causes altered carboxyl-terminal structure in the aryl hydrocarbon receptor of the most 2,3,7,8- tetrachlorodibenzo-p-dioxin-resistant rat strain
-
Pohjanvirta, R., Wong, J.M., Li, W., Harper, P.A., Tuomisto, J. and Okey, A.B. (1998): Point mutation in intron sequence causes altered carboxyl-terminal structure in the aryl hydrocarbon receptor of the most 2,3,7,8- tetrachlorodibenzo-p-dioxin-resistant rat strain. Mol. Pharmacol., 54, 86-93.
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 86-93
-
-
Pohjanvirta, R.1
Wong, J.M.2
Li, W.3
Harper, P.A.4
Tuomisto, J.5
Okey, A.B.6
-
24
-
-
0034723264
-
Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest
-
Puga, A., Barnes, S.J., Dalton, T.P., Chang, C., Knudsen, E.S. and Maier, M.A. (2000): Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest. J. Biol. Chem., 275, 2943-2950.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2943-2950
-
-
Puga, A.1
Barnes, S.J.2
Dalton, T.P.3
Chang, C.4
Knudsen, E.S.5
Maier, M.A.6
-
26
-
-
27144465972
-
Lack of CYP1A1 expression is involved in unresponsiveness of the human hepatoma cell line SK-HEP-1 to dioxin
-
Shiizaki, K., Ohsako, S., Koyama, T., Nagata, R., Yonemoto, J. and Tohyama, C. (2005): Lack of CYP1A1 expression is involved in unresponsiveness of the human hepatoma cell line SK-HEP-1 to dioxin. Toxicol. Lett., 160, 22-33.
-
(2005)
Toxicol. Lett.
, vol.160
, pp. 22-33
-
-
Shiizaki, K.1
Ohsako, S.2
Koyama, T.3
Nagata, R.4
Yonemoto, J.5
Tohyama, C.6
-
27
-
-
3242789451
-
Pattern of male reproductive system effects after in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in three differentially TCDD-sensitive rat lines
-
Simanainen, U., Haavisto, T., Tuomisto, J.T., Paranko, J., Toppari, J., Tuomisto, J., Peterson, R.E. and Viluksela, M. (2004): Pattern of male reproductive system effects after in utero and lactational 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) exposure in three differentially TCDD-sensitive rat lines. Toxicol. Sci., 80, 101-108.
-
(2004)
Toxicol. Sci.
, vol.80
, pp. 101-108
-
-
Simanainen, U.1
Haavisto, T.2
Tuomisto, J.T.3
Paranko, J.4
Toppari, J.5
Tuomisto, J.6
Peterson, R.E.7
Viluksela, M.8
-
28
-
-
0037095038
-
Structure-activity relationships and dose responses of polychlorinated dibenzo-p-dioxins for short-term effects in 2,3,7,8-tetrachlorodibenzo-p-dioxin- resistant and -sensitive rat strains
-
Simanainen, U., Tuomisto, J.T., Tuomisto, J. and Viluksela, M. (2002): Structure-activity relationships and dose responses of polychlorinated dibenzo-p-dioxins for short-term effects in 2,3,7,8-tetrachlorodibenzo-p-dioxin- resistant and -sensitive rat strains. Toxicol. Appl. Pharmacol., 181, 38-47.
-
(2002)
Toxicol. Appl. Pharmacol.
, vol.181
, pp. 38-47
-
-
Simanainen, U.1
Tuomisto, J.T.2
Tuomisto, J.3
Viluksela, M.4
-
29
-
-
0032522828
-
Thymic alterations induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin are strictly dependent on aryl hydrocarbon receptor activation in hemopoietic cells
-
Staples, J.E., Murante, F.G., Fiore, N.C., Gasiewicz, T.A. and Silverstone, A.E. (1998): Thymic alterations induced by 2,3,7,8- tetrachlorodibenzo-p-dioxin are strictly dependent on aryl hydrocarbon receptor activation in hemopoietic cells. J. Immunol., 160, 3844-3854.
-
(1998)
J. Immunol.
, vol.160
, pp. 3844-3854
-
-
Staples, J.E.1
Murante, F.G.2
Fiore, N.C.3
Gasiewicz, T.A.4
Silverstone, A.E.5
-
30
-
-
0033517778
-
Construction of Epstein-Barr virus-based expression vector containing mini-oriP
-
Tanaka, J., Miwa, Y., Miyoshi, K., Ueno, A. and Inoue, H. (1999): Construction of Epstein-Barr virus-based expression vector containing mini-oriP. Biochem. Biophys. Res. Commun., 264, 938-943.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.264
, pp. 938-943
-
-
Tanaka, J.1
Miwa, Y.2
Miyoshi, K.3
Ueno, A.4
Inoue, H.5
-
31
-
-
0032957695
-
Ah receptor and NF-kappaB interactions, a potential mechanism for dioxin toxicity
-
Tian, Y., Ke, S., Denison, M.S., Rabson, A.B. and Gallo, M.A. (1999): Ah receptor and NF-kappaB interactions, a potential mechanism for dioxin toxicity. J. Biol. Chem., 274, 510-515.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 510-515
-
-
Tian, Y.1
Ke, S.2
Denison, M.S.3
Rabson, A.B.4
Gallo, M.A.5
-
32
-
-
0033062111
-
The AH receptor and a novel gene determine acute toxic responses to TCDD: Segregation of the resistant alleles to different rat lines
-
DOI 10.1006/taap.1998.8564
-
Tuomisto, J.T., Viluksela, M., Pohjanvirta, R. and Tuomisto, J. (1999): The AH receptor and a novel gene determine acute toxic responses to TCDD: segregation of the resistant alleles to different rat lines. Toxicol. Appl. Pharmacol., 155, 71-81. (Pubitemid 29102763)
-
(1999)
Toxicology and Applied Pharmacology
, vol.155
, Issue.1
, pp. 71-81
-
-
Tuomisto, J.T.1
Viluksela, M.2
Pohjanvirta, R.3
Tuomisto, J.4
-
33
-
-
0034671413
-
Liver tumor-promoting activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive and TCDD-resistant rat strains
-
Viluksela, M., Bag er, Y., Tuomisto, J.T., Scheu, G., Unkila, M., Pohjanvirta, R., Flodström, S., Kosma, V.-M., Mäki-Paakkanen, J., Vartiainen, T., Klimm, C., Schramm, K.-W., Wärngård L. and Tuomisto J. (2000): Liver tumor-promoting activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive and TCDD-resistant rat strains. Cancer Res., 60, 6911-6920.
-
(2000)
Cancer Res.
, vol.60
, pp. 6911-6920
-
-
Viluksela, M.1
Bag Er, Y.2
Tuomisto, J.T.3
Scheu, G.4
Unkila, M.5
Pohjanvirta, R.6
Flodström, S.7
Kosma, V.-M.8
Mäki-Paakkanen, J.9
Vartiainen, T.10
Klimm, C.11
Schramm, K.-W.12
Wärngård, L.13
Tuomisto, J.14
-
34
-
-
0029858387
-
TNF- And cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
-
DOI 10.1126/science.274.5288.784
-
Wang, C.Y., Mayo, M.W. and Baldwin, A.S.Jr. (1996): TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science, 274, 784-787. (Pubitemid 26398259)
-
(1996)
Science
, vol.274
, Issue.5288
, pp. 784-787
-
-
Wang, C.-Y.1
Mayo, M.W.2
Baldwin Jr., A.S.3
|