-
1
-
-
0037477740
-
A delicate balance: Homeostatic control of copper uptake and distribution
-
Pena, M. M., Lee, J., and Thiele, D. J. (1999) A delicate balance: Homeostatic control of copper uptake and distribution. J. Nutr. 129, 1251-1260.
-
(1999)
J. Nutr.
, vol.129
, pp. 1251-1260
-
-
Pena, M.M.1
Lee, J.2
Thiele, D.J.3
-
2
-
-
0031981647
-
Effect of copper deficiency on prenatal development and pregnancy outcome
-
Keen, C. L., Uriu-Hare, J. Y., Hawk, S. N., Jankowski, M. A., Daston, G. P., Kwik-Uribe, C. L., and Rucker, R. B. (1998) Effect of copper deficiency on prenatal development and pregnancy outcome. Am. J. Clin. Nutr. 67, 1003S-1011S.
-
(1998)
Am. J. Clin. Nutr.
, vol.67
-
-
Keen, C.L.1
Uriu-Hare, J.Y.2
Hawk, S.N.3
Jankowski, M.A.4
Daston, G.P.5
Kwik-Uribe, C.L.6
Rucker, R.B.7
-
3
-
-
1842608738
-
Hereditary causes of disturbed iron homeostasis in the central nervous system
-
DOI 10.1196/annals.1306.022
-
Ponka, P. (2004) Hereditary causes of disturbed iron homeostasis in the central nervous system. Ann. N.Y. Acad. Sci. 1012, 267-281. (Pubitemid 38453531)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1012
, pp. 267-281
-
-
Ponka, P.1
-
4
-
-
0032887626
-
The role of copper in neurodegenerative disease
-
DOI 10.1006/nbdi.1999.0250
-
Waggoner, D. J., Bartnikas, T. B., and Gitlin, J. D. (1999) The role of copper in neurodegenerative disease. Neurobiol. Dis. 6, 221-230. (Pubitemid 29470034)
-
(1999)
Neurobiology of Disease
, vol.6
, Issue.4
, pp. 221-230
-
-
Waggoner, D.J.1
Bartnikas, T.B.2
Gitlin, J.D.3
-
5
-
-
36448983237
-
Molecular pathogenesis of Wilson and Menkes disease: Correlation of mutations with molecular defects and disease phenotypes
-
de Bie, P., Muller, P., Wijmenga, C., and Klomp, L. W. (2007) Molecular pathogenesis of Wilson and Menkes disease: Correlation of mutations with molecular defects and disease phenotypes. J. Med. Genet. 44, 673-688.
-
(2007)
J. Med. Genet.
, vol.44
, pp. 673-688
-
-
De Bie, P.1
Muller, P.2
Wijmenga, C.3
Klomp, L.W.4
-
6
-
-
0027980901
-
Rapid induction of Alzheimer Aβ amyloid formation by zinc
-
Bush, A. I., Pettingell, W. H., Multhaup, G., d Paradis, M., Vonsattel, J. P., Gusella, J. F., Beyreuther, K., Masters, C. L., and Tanzi, R. E. (1994) Rapid induction of Alzheimer Aβ amyloid formation by zinc. Science 265, 1464-1467.
-
(1994)
Science
, vol.265
, pp. 1464-1467
-
-
Bush, A.I.1
Pettingell, W.H.2
Multhaup, G.3
D Paradis, M.4
Vonsattel, J.P.5
Gusella, J.F.6
Beyreuther, K.7
Masters, C.L.8
Tanzi, R.E.9
-
7
-
-
0032507975
-
Copper, iron and zinc in Alzheimer's disease senile plaques
-
Lovell, M. A., Robertson, J. D., Teesdale, W. J., Campbell, J. L., and Markesbery, W. R. (1998) Copper, iron and zinc in Alzheimer's disease senile plaques. J. Neurol. Sci. 158, 47-52.
-
(1998)
J. Neurol. Sci.
, vol.158
, pp. 47-52
-
-
Lovell, M.A.1
Robertson, J.D.2
Teesdale, W.J.3
Campbell, J.L.4
Markesbery, W.R.5
-
8
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
DOI 10.1038/325733a0
-
Kang, J., Lemaire, H. G., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K. H., Multhaup, G., Beyreuther, K., and Muller-Hill, B. (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325, 733-736. (Pubitemid 17054046)
-
(1987)
Nature
, vol.325
, Issue.6106
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.-G.2
Unterbeck, A.3
-
9
-
-
0029933153
-
The role of APP processing and trafficking pathways in the formation of amyloid β-protein
-
Selkoe, D. J., Yamazaki, T., Citron, M., Podlisny, M. B., Koo, E. H., Teplow, D. B., and Haass, C. (1996) The role of APP processing and trafficking pathways in the formation of amyloid β-protein. Ann. N. Y. Acad. Sci. 777, 57-64. (Pubitemid 26149170)
-
(1996)
Annals of the New York Academy of Sciences
, vol.777
, pp. 57-64
-
-
Selkoe, D.J.1
Yamazaki, T.2
Citron, M.3
Podlisny, M.B.4
Koo, E.H.5
Teplow, D.B.6
Haass, C.7
-
10
-
-
0028177269
-
The betaA4 amyloid prepcursor protein binding to copper
-
DOI 10.1016/0014-5793(94)00658-X
-
Hesse, L., Beher, D., Masters, C. L., and Multhaup, G. (1994) The βA4 amyloid precursor protein binding to copper. FEBS Lett. 349, 109-116. (Pubitemid 2119590)
-
(1994)
FEBS Letters
, vol.349
, Issue.1
, pp. 109-116
-
-
Hesse, L.1
Beher, D.2
Masters, C.L.3
Multhaup, G.4
-
11
-
-
0029935396
-
The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper (I)
-
Multhaup, G., Schlicksupp, A., Hesse, L., Beher, D., Ruppert, T., Masters, C. L., and Beyreuther, K. (1996) The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper (I). Science 271, 1406-1409.
-
(1996)
Science
, vol.271
, pp. 1406-1409
-
-
Multhaup, G.1
Schlicksupp, A.2
Hesse, L.3
Beher, D.4
Ruppert, T.5
Masters, C.L.6
Beyreuther, K.7
-
12
-
-
0032830357
-
Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice
-
DOI 10.1016/S0006-8993(99)01861-2, PII S0006899399018612
-
White, A. R., Reyes, R., Mercer, J. F., Camakaris, J., Zheng, H., Bush, A. I., Multhaup, G., Beyreuther, K., Masters, C. L., and Cappai, R. (1999) Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice. Brain Res. 842, 439-444. (Pubitemid 29475178)
-
(1999)
Brain Research
, vol.842
, Issue.2
, pp. 439-444
-
-
White, A.R.1
Reyes, R.2
Mercer, J.F.B.3
Camakaris, J.4
Zheng, H.5
Bush, A.I.6
Multhaup, G.7
Beyreuther, K.8
Masters, C.L.9
Cappai, R.10
-
13
-
-
10744226316
-
Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Aβ production in APP23 transgenic mice
-
Bayer, T. A., Schafer, S., Simons, A., Kemmling, A., Kamer, T., Tepest, R., Eckert, A., Schussel, K., Eikenberg, O., Sturchler-Pierrat, C., Abramowski, D., Staufenbiel, M., and Multhaup, G. (2003) Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Aβ production in APP23 transgenic mice. Proc. Natl. Acad. Sci. U.S.A. 100, 14187-14192.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 14187-14192
-
-
Bayer, T.A.1
Schafer, S.2
Simons, A.3
Kemmling, A.4
Kamer, T.5
Tepest, R.6
Eckert, A.7
Schussel, K.8
Eikenberg, O.9
Sturchler-Pierrat, C.10
Abramowski, D.11
Staufenbiel, M.12
Multhaup, G.13
-
14
-
-
2442586535
-
Copper depletion down-regulates expression of the Alzheimer's disease amyloid-β precursor protein gene
-
Bellingham, S. A., Lahiri, D. K., Maloney, B., La Fontaine, S., Multhaup, G., and Camakaris, J. (2004) Copper depletion down-regulates expression of the Alzheimer's disease amyloid-β precursor protein gene. J. Biol. Chem. 279, 20378-20386.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20378-20386
-
-
Bellingham, S.A.1
Lahiri, D.K.2
Maloney, B.3
La Fontaine, S.4
Multhaup, G.5
Camakaris, J.6
-
15
-
-
10644280708
-
Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease
-
DOI 10.1074/jbc.M407410200
-
Treiber, C., Simons, A., Strauss, M., Hafner, M., Cappai, R., Bayer, T. A., and Multhaup, G. (2004) Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease. J. Biol. Chem. 279, 51958-51964. (Pubitemid 39656565)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.50
, pp. 51958-51964
-
-
Treiber, C.1
Simons, A.2
Strauss, M.3
Hafner, M.4
Cappai, R.5
Bayer, T.A.6
Multhaup, G.7
-
16
-
-
10744228112
-
In vivo reduction of amyloid-β by a mutant copper transporter
-
Phinney, A. L., Drisaldi, B., Schmidt, S. D., Lugowski, S., Coronado, V., Liang, Y., Horne, P., Yang, J., Sekoulidis, J., Coomaraswamy, J., Chishti, M. A., Cox, D. W., Mathews, P. M., Nixon, R. A., Carlson, G. A., St George-Hyslop, P., and Westaway, D. (2003) In vivo reduction of amyloid-β by a mutant copper transporter. Proc. Natl. Acad. Sci. U.S.A. 100, 14193-14198.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 14193-14198
-
-
Phinney, A.L.1
Drisaldi, B.2
Schmidt, S.D.3
Lugowski, S.4
Coronado, V.5
Liang, Y.6
Horne, P.7
Yang, J.8
Sekoulidis, J.9
Coomaraswamy, J.10
Chishti, M.A.11
Cox, D.W.12
Mathews, P.M.13
Nixon, R.A.14
Carlson, G.A.15
St George-Hyslop, P.16
Westaway, D.17
-
17
-
-
49749092065
-
Intake of copper has no effect on cognition in patients with mild Alzheimer's disease: A pilot phase 2 clinical trial
-
Kessler, H., Bayer, T. A., Bach, D., Schneider-Axmann, T., Supprian, T., Herrmann, W., Haber, M., Multhaup, G., Falkai, P., and Pajonk, F. G. (2008) Intake of copper has no effect on cognition in patients with mild Alzheimer's disease: A pilot phase 2 clinical trial. J. Neural Transm. 115, 1181-1187.
-
(2008)
J. Neural Transm.
, vol.115
, pp. 1181-1187
-
-
Kessler, H.1
Bayer, T.A.2
Bach, D.3
Schneider-Axmann, T.4
Supprian, T.5
Herrmann, W.6
Haber, M.7
Multhaup, G.8
Falkai, P.9
Pajonk, F.G.10
-
18
-
-
46149107512
-
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Aβ
-
Adlard, P. A., Cherny, R. A., Finkelstein, D. I., Gautier, E., Robb, E., Cortes, M., Volitakis, I., Liu, X., Smith, J. P., Perez, K., Laughton, K., Li, Q. X., Charman, S. A., Nicolazzo, J. A., Wilkins, S., Deleva, K., Lynch, T., Kok, G., Ritchie, C. W., Tanzi, R. E., Cappai, R., Masters, C. L., Barnham, K. J., and Bush, A. I. (2008) Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Aβ. Neuron 59, 43-55.
-
(2008)
Neuron
, vol.59
, pp. 43-55
-
-
Adlard, P.A.1
Cherny, R.A.2
Finkelstein, D.I.3
Gautier, E.4
Robb, E.5
Cortes, M.6
Volitakis, I.7
Liu, X.8
Smith, J.P.9
Perez, K.10
Laughton, K.11
Li, Q.X.12
Charman, S.A.13
Nicolazzo, J.A.14
Wilkins, S.15
Deleva, K.16
Lynch, T.17
Kok, G.18
Ritchie, C.W.19
Tanzi, R.E.20
Cappai, R.21
Masters, C.L.22
Barnham, K.J.23
Bush, A.I.24
more..
-
19
-
-
34249686578
-
Pro-apoptotic activity of novel isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage
-
DOI 10.1074/jbc.M610927200
-
Filomeni, G., Cerchiaro, G., Da Costa Ferreira, A. M., De Martino, A., Pedersen, J. Z., Rotilio, G., and Ciriolo, M. R. (2007) Pro-apoptotic activity of novel Isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage. J. Biol. Chem. 282, 12010-12021. (Pubitemid 47100713)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.16
, pp. 12010-12021
-
-
Filomeni, G.1
Cerchiaro, G.2
Da Costa Ferreira, A.M.3
De Martino, A.4
Pedersen, J.Z.5
Rotilio, G.6
Ciriolo, M.R.7
-
20
-
-
4644238758
-
The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human β-amyloid precursor protein transgenic mice
-
Lee, J. Y., Friedman, J. E., Angel, I., Kozak, A., and Koh, J. Y. (2004) The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human β-amyloid precursor protein transgenic mice. Neurobiol. Aging 25, 1315-1321.
-
(2004)
Neurobiol. Aging
, vol.25
, pp. 1315-1321
-
-
Lee, J.Y.1
Friedman, J.E.2
Angel, I.3
Kozak, A.4
Koh, J.Y.5
-
21
-
-
33644852944
-
Micelle carrier system in clinical trial
-
Matsumura, Y. (2006) [Micelle carrier system in clinical trial]. Nippon Rinsho 64, 316-321.
-
(2006)
Nippon Rinsho
, vol.64
, pp. 316-321
-
-
Matsumura, Y.1
-
22
-
-
0035816145
-
Development of the polymer micelle carrier system for doxorubicin
-
DOI 10.1016/S0168-3659(01)00341-8, PII S0168365901003418
-
Nakanishi, T., Fukushima, S., Okamoto, K., Suzuki, M., Matsumura, Y., Yokoyama, M., Okano, T., Sakurai, Y., and Kataoka, K. (2001) Development of the polymer micelle carrier system for doxorubicin. J. Controlled Release 74, 295-302. (Pubitemid 32727635)
-
(2001)
Journal of Controlled Release
, vol.74
, Issue.1-3
, pp. 295-302
-
-
Nakanishi, T.1
Fukushima, S.2
Okamoto, K.3
Suzuki, M.4
Matsumura, Y.5
Yokoyama, M.6
Okano, T.7
Sakurai, Y.8
Kataoka, K.9
-
23
-
-
33746965448
-
Polymer conjugates for drug targeting. From inspired to inspiration!
-
Duncan, R. (2006) Polymer conjugates for drug targeting. From inspired to inspiration!. J. Drug Targeting 14, 333-335.
-
(2006)
J. Drug Targeting
, vol.14
, pp. 333-335
-
-
Duncan, R.1
-
24
-
-
34247233673
-
Supramolecular aggregates of dendritic multishell architectures as universal nanocarriers
-
DOI 10.1002/anie.200603801
-
Radowski, M. R., Shukla, A., von Berlepsch, H., Böttcher, C., Pickaert, G., Rehage, H., and Haag, R. (2007) Supramolecular aggregates of dendritic multishell architectures as universal nanocarriers. Angew. Chem., Int. Ed. 46, 1265-1269. (Pubitemid 46981371)
-
(2007)
Angewandte Chemie - International Edition
, vol.46
, Issue.8
, pp. 1265-1269
-
-
Radowski, M.R.1
Shukla, A.2
Von Berlepsch, H.3
Bottcher, C.4
Pickaert, G.5
Rehage, H.6
Haag, R.7
-
25
-
-
26944495320
-
Water-Soluble Dendritic Architectures with Carbohydrate Shells for the Templation and Stabilization of Catalytically Active Metal Nanoparticles
-
Kräamer, M., Pérignon, N., Haag, R., Marty, J.-D., Thomann, R., Lauth-de Viguerie, N., and Mingotaud, C. (2005) Water-Soluble Dendritic Architectures with Carbohydrate Shells for the Templation and Stabilization of Catalytically Active Metal Nanoparticles. Macromolecules 38, 8308-8315.
-
(2005)
Macromolecules
, vol.38
, pp. 8308-8315
-
-
Kräamer, M.1
Pérignon, N.2
Haag, R.3
Marty, J.-D.4
Thomann, R.5
Lauth-de Viguerie, N.6
Mingotaud, C.7
-
26
-
-
0034867043
-
Dendrimer-encapsulated metal nanoparticles: Synthesis, characterization, and applications to catalysis
-
Crooks, R. M., Zhao, M., Sun, L., Chechik, V., and Yeung, L. K. (2001) Dendrimer-encapsulated metal nanoparticles: Synthesis, characterization, and applications to catalysis. Acc. Chem. Res. 34, 181-190.
-
(2001)
Acc. Chem. Res.
, vol.34
, pp. 181-190
-
-
Crooks, R.M.1
Zhao, M.2
Sun, L.3
Chechik, V.4
Yeung, L.K.5
-
27
-
-
0037199460
-
Evidence for a copper-binding superfamily of the amyloid precursor protein
-
Simons, A., Ruppert, T., Schmidt, C., Schlicksupp, A., Pipkorn, R., Reed, J., Masters, C. L., White, A. R., Cappai, R., Beyreuther, K., Bayer, T. A., and Multhaup, G. (2002) Evidence for a copper-binding superfamily of the amyloid precursor protein. Biochemistry 41, 9310-9320.
-
(2002)
Biochemistry
, vol.41
, pp. 9310-9320
-
-
Simons, A.1
Ruppert, T.2
Schmidt, C.3
Schlicksupp, A.4
Pipkorn, R.5
Reed, J.6
Masters, C.L.7
White, A.R.8
Cappai, R.9
Beyreuther, K.10
Bayer, T.A.11
Multhaup, G.12
-
28
-
-
33947597857
-
GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Aβ42
-
DOI 10.1038/sj.emboj.7601616, PII 7601616
-
Munter, L. M., Voigt, P., Harmeier, A., Kaden, D., Gottschalk, K. E., Weise, C., Pipkorn, R., Schaefer, M., Langosch, D., and Multhaup, G. (2007) GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Aβ42. EMBO J. 26, 1702-1712. (Pubitemid 46480941)
-
(2007)
EMBO Journal
, vol.26
, Issue.6
, pp. 1702-1712
-
-
Munter, L.-M.1
Voigt, P.2
Harmeier, A.3
Kaden, D.4
Gottschalk, K.E.5
Weise, C.6
Pipkorn, R.7
Schaefer, M.8
Langosch, D.9
Multhaup, G.10
-
29
-
-
0034709641
-
Differential contribution of superoxide dismutase activity by prion protein in vivo
-
DOI 10.1006/bbrc.2000.2911
-
Wong, B. S., Pan, T., Liu, T., Li, R., Gambetti, P., and Sy, M. S. (2000) Differential contribution of superoxide dismutase activity by prion protein in vivo. Biochem. Biophys. Res. Commun. 273, 136-139. (Pubitemid 30426875)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.273
, Issue.1
, pp. 136-139
-
-
Wong, B.-S.1
Pan, T.2
Liu, T.3
Li, R.4
Gambetti, P.5
Sy, M.-S.6
-
30
-
-
33746932518
-
Activation of superoxide dismutases: Putting the metal to the pedal
-
Culotta, V. C., Yang, M., and O'Halloran, T. V. (2006) Activation of superoxide dismutases: Putting the metal to the pedal. Biochim. Biophys. Acta 1763, 747-758.
-
(2006)
Biochim. Biophys. Acta
, vol.1763
, pp. 747-758
-
-
Culotta, V.C.1
Yang, M.2
O'Halloran, T.V.3
-
31
-
-
0033430087
-
Copper inhibits β-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion
-
Borchardt, T., Camakaris, J., Cappai, R., Masters, C. L., Beyreuther, K., and Multhaup, G. (1999) Copper inhibits β-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion. Biochem. J. 344(Part 2), 461-467.
-
(1999)
Biochem. J.
, vol.344
, Issue.PART 2
, pp. 461-467
-
-
Borchardt, T.1
Camakaris, J.2
Cappai, R.3
Masters, C.L.4
Beyreuther, K.5
Multhaup, G.6
-
32
-
-
14844312860
-
Metal complexes with aromatic N-containing ligands as potential agents in cancer treatment
-
Zhao, G., and Lin, H. (2005) Metal complexes with aromatic N-containing ligands as potential agents in cancer treatment. Curr. Med. Chem. Anticancer Agents 5, 137-147.
-
(2005)
Curr. Med. Chem. Anticancer Agents
, vol.5
, pp. 137-147
-
-
Zhao, G.1
Lin, H.2
-
33
-
-
33749235493
-
Copper deficiency myelopathy (human swayback)
-
Kumar, N. (2006) Copper deficiency myelopathy (human swayback). Mayo Clin. Proc. 81, 1371-1384. (Pubitemid 44484976)
-
(2006)
Mayo Clinic Proceedings
, vol.81
, Issue.10
, pp. 1371-1384
-
-
Kumar, N.1
-
34
-
-
20444440369
-
Metals and amyloid-β in Alzheimer's disease
-
Maynard, C. J., Bush, A. I., Masters, C. L., Cappai, R., and Li, Q. X. (2005) Metals and amyloid-β in Alzheimer's disease. Int. J. Exp. Pathol. 86, 147-159.
-
(2005)
Int. J. Exp. Pathol.
, vol.86
, pp. 147-159
-
-
Maynard, C.J.1
Bush, A.I.2
Masters, C.L.3
Cappai, R.4
Li, Q.X.5
-
35
-
-
28744445460
-
Dendrimer biocompatibility and toxicity
-
DOI 10.1016/j.addr.2005.09.019, PII S0169409X0500195X, Dendrimers: a Versatile Targeting Platform
-
Duncan, R., and Izzo, L. (2005) Dendrimer biocompatibility and toxicity. Adv. Drug Delivery Rev. 57, 2215-2237. (Pubitemid 41759394)
-
(2005)
Advanced Drug Delivery Reviews
, vol.57
, Issue.15
, pp. 2215-2237
-
-
Duncan, R.1
Izzo, L.2
-
36
-
-
0034728692
-
An approach to glycerol dendrimers and pseudo-dendritic polyglycerols [6]
-
DOI 10.1021/ja994363e
-
Haag, R., Sunder, A., and Stumbé, J. F. (2000) An Approach to Glycerol Dendrimers and Pseudo-Dendritic Polyglycerols. J. Am. Chem. Soc. 122, 2954-2955. (Pubitemid 30191060)
-
(2000)
Journal of the American Chemical Society
, vol.122
, Issue.12
, pp. 2954-2955
-
-
Haag, R.1
Sunder, A.2
Stumbe, J.-F.3
-
37
-
-
33746985455
-
PH-Responsive dendritic core-shell architectures as amphiphilic nanocarriers for polar drugs
-
DOI 10.1080/10611860600834011, PII L18362522830HH12
-
Xu, S., Krämer, M., and Haag, R. (2006) pH-Responsive dendritic core-shell architectures as amphiphilic nanocarriers for polar drugs. J. Drug Targeting 14, 367-374. (Pubitemid 44203517)
-
(2006)
Journal of Drug Targeting
, vol.14
, Issue.6
, pp. 367-374
-
-
Xu, S.1
Kramer, M.2
Haag, R.3
-
38
-
-
41949115990
-
Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-β peptide
-
Donnelly, P. S., Caragounis, A., Du, T., Laughton, K. M., Volitakis, I., Cherny, R. A., Sharples, R. A., Hill, A. F., Li, Q. X., Masters, C. L., Barnham, K. J., and White, A. R. (2008) Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-β peptide. J. Biol. Chem. 283, 4568-4577.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 4568-4577
-
-
Donnelly, P.S.1
Caragounis, A.2
Du, T.3
Laughton, K.M.4
Volitakis, I.5
Cherny, R.A.6
Sharples, R.A.7
Hill, A.F.8
Li, Q.X.9
Masters, C.L.10
Barnham, K.J.11
White, A.R.12
-
39
-
-
33745860362
-
Degradation of the Alzheimer disease amyloid β-peptide by metal-dependent up-regulation of metalloprotease activity
-
DOI 10.1074/jbc.M602487200
-
White, A. R., Du, T., Laughton, K. M., Volitakis, I., Sharples, R. A., Xilinas, M. E., Hoke, D. E., Holsinger, R. M., Evin, G., Cherny, R. A., Hill, A. F., Barnham, K. J., Li, Q. X., Bush, A. I., and Masters, C. L. (2006) Degradation of the Alzheimer disease amyloid β-peptide by metal-dependent up-regulation of metalloprotease activity. J. Biol. Chem. 281, 17670-17680. (Pubitemid 44035565)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.26
, pp. 17670-17680
-
-
White, A.R.1
Du, T.2
Laughton, K.M.3
Volitakis, I.4
Sharples, R.A.5
Xilinas, M.E.6
Hoke, D.E.7
Holsinger, R.M.D.8
Evin, G.9
Cherny, R.A.10
Hill, A.F.11
Barnham, K.J.12
Li, Q.-X.13
Bush, A.I.14
Masters, C.L.15
-
40
-
-
0037160028
-
Overexpression of Alzheimer's disease amyloid-β opposes the agedependent elevations of brain copper and iron
-
Maynard, C. J., Cappai, R., Volitakis, I., Cherny, R. A., White, A. R., Beyreuther, K., Masters, C. L., Bush, A. I., and Li, Q. X. (2002) Overexpression of Alzheimer's disease amyloid-β opposes the agedependent elevations of brain copper and iron. J. Biol. Chem. 277, 44670-44676.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44670-44676
-
-
Maynard, C.J.1
Cappai, R.2
Volitakis, I.3
Cherny, R.A.4
White, A.R.5
Beyreuther, K.6
Masters, C.L.7
Bush, A.I.8
Li, Q.X.9
-
41
-
-
10744224267
-
Metal-Protein Attenuation with Iodochlorhydroxyquin (Clioquinol) Targeting Aβ Amyloid Deposition and Toxicity in Alzheimer Disease: A Pilot Phase 2 Clinical Trial
-
DOI 10.1001/archneur.60.12.1685
-
Ritchie, C. W., Bush, A. I., Mackinnon, A., Macfarlane, S., Mastwyk, M., MacGregor, L., Kiers, L., Cherny, R., Li, Q. X., Tammer, A., Carrington, D., Mavros, C., Volitakis, I., Xilinas, M., Ames, D., Davis, S., Beyreuther, K., Tanzi, R. E., and Masters, C. L. (2003) Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Aβ amyloid deposition and toxicity in Alzheimer disease: A pilot phase 2 clinical trial. Arch. Neurol. 60, 1685-1691. (Pubitemid 37521621)
-
(2003)
Archives of Neurology
, vol.60
, Issue.12
, pp. 1685-1691
-
-
Ritchie, C.W.1
Bush, A.I.2
Mackinnon, A.3
Macfarlane, S.4
Mastwyk, M.5
MacGregor, L.6
Kiers, L.7
Cherny, R.8
Li, Q.-X.9
Tammer, A.10
Carrington, D.11
Mavros, C.12
Volitakis, I.13
Xilinas, M.14
Ames, D.15
Davis, S.16
Beyreuther, K.17
Tanzi, R.E.18
Masters, C.L.19
-
42
-
-
48949098573
-
Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: A phase IIa, double-blind, randomised, placebo-controlled trial
-
Lannfelt, L., Blennow, K., Zetterberg, H., Batsman, S., Ames, D., Harrison, J., Masters, C. L., Targum, S., Bush, A. I., Murdoch, R., Wilson, J., and Ritchie, C. W. (2008) Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: A phase IIa, double-blind, randomised, placebo-controlled trial. Lancet Neurol. 7, 779-786.
-
(2008)
Lancet Neurol.
, vol.7
, pp. 779-786
-
-
Lannfelt, L.1
Blennow, K.2
Zetterberg, H.3
Batsman, S.4
Ames, D.5
Harrison, J.6
Masters, C.L.7
Targum, S.8
Bush, A.I.9
Murdoch, R.10
Wilson, J.11
Ritchie, C.W.12
-
43
-
-
0010920059
-
The Dendritic Box: Shape-Selective Liberation of Encapsulated Guests
-
Jansen, J. F. G. A., Meijer, E. W., and de Brabander-van den Berg, E. M. M. (1995) The Dendritic Box: Shape-Selective Liberation of Encapsulated Guests. J. Am. Chem. Soc. 117, 4417-4418.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 4417-4418
-
-
Jansen, J.F.G.A.1
Meijer, E.W.2
De Brabander-van Den Berg, E.M.M.3
-
44
-
-
85047699037
-
PH-responsive molecular nanocarriers based on dendritic core-shell architectures
-
DOI 10.1002/1521-3773(20021115)41:22<4252::AID-ANIE4252>3.0.CO;2-F
-
Krämer, M., Stumbe, J. F., Turk, H., Krause, S., Komp, A., Delineau, L., Prokhorova, S., Kautz, H., and Haag, R. (2002) pH-responsive molecular nanocarriers based on dendritic core-shell architectures. Angew. Chem., Int. Ed. 41, 4252-4256. (Pubitemid 35398245)
-
(2002)
Angewandte Chemie - International Edition
, vol.41
, Issue.22
, pp. 4252-4256
-
-
Kramer, M.1
Stumbe, J.-F.2
Turk, H.3
Krause, S.4
Komp, A.5
Delineau, L.6
Prokhorova, S.7
Kautz, H.8
Haag, R.9
-
45
-
-
2442471606
-
Intracellular Copper Transport in Mammals
-
Prohaska, J. R., and Gybina, A. A. (2004) Intracellular copper transport in mammals. J. Nutr. 134, 1003-1006. (Pubitemid 38619931)
-
(2004)
Journal of Nutrition
, vol.134
, Issue.5
, pp. 1003-1006
-
-
Prohaska, J.R.1
Gybina, A.A.2
-
46
-
-
57649221135
-
Amyloid precursor protein trafficking, processing, and function
-
Thinakaran, G., and Koo, E. H. (2008) Amyloid precursor protein trafficking, processing, and function. J. Biol. Chem. 283, 29615-29619.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 29615-29619
-
-
Thinakaran, G.1
Koo, E.H.2
-
47
-
-
21344440550
-
Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis
-
Chen, D., Peng, F., Cui, Q. C., Daniel, K. G., Orlu, S., Liu, J., and Dou, Q. P. (2005) Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis. Front. Biosci. 10, 2932-2939. (Pubitemid 40910532)
-
(2005)
Frontiers in Bioscience
, vol.10
, Issue.SUPPL. 3
, pp. 2932-2939
-
-
Chen, D.1
Peng, F.2
Cui, Q.C.3
Daniel, K.G.4
Orlu, S.5
Liu, J.6
Dou, Q.P.7
-
48
-
-
1542270307
-
Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells
-
DOI 10.1016/j.bcp.2003.10.031, PII S0006295203008876
-
Daniel, K. G., Gupta, P., Harbach, R. H., Guida, W. C., and Dou, Q. P. (2004) Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells. Biochem. Pharmacol. 67, 1139-1151. (Pubitemid 38296793)
-
(2004)
Biochemical Pharmacology
, vol.67
, Issue.6
, pp. 1139-1151
-
-
Daniel, K.G.1
Gupta, P.2
Harbach, R.H.3
Guida, W.C.4
Dou, Q.P.5
-
49
-
-
0036943656
-
Copper bis(thiosemicarbazone) complexes as hypoxia imaging agents: Structure-activity relationships
-
Dearling, J. L., Lewis, J. S., Mullen, G. E., Welch, M. J., and Blower, P. J. (2002) Copper bis(thiosemicarbazone) complexes as hypoxia imaging agents: Structure-activity relationships. J. Biol. Inorg. Chem. 7, 249-259.
-
(2002)
J. Biol. Inorg. Chem.
, vol.7
, pp. 249-259
-
-
Dearling, J.L.1
Lewis, J.S.2
Mullen, G.E.3
Welch, M.J.4
Blower, P.J.5
-
50
-
-
0023747378
-
Copper(II) bis(thiosemicarbazone) complexes as potential tracers for evaluation of cerebral and myocardial blood flow with PET
-
Green, M. A., Klippenstein, D. L., and Tennison, J. R. (1988) Copper (II) bis(thiosemicarbazone) complexes as potential tracers for evaluation of cerebral and myocardial blood flow with PET. J. Nucl. Med. 29, 1549-1557. (Pubitemid 18213818)
-
(1988)
Journal of Nuclear Medicine
, vol.29
, Issue.9
, pp. 1549-1557
-
-
Green, M.A.1
Klippenstein, D.L.2
Tennison, J.R.3
-
51
-
-
23744490884
-
Dosimetry of 60/61/62/64Cu-ATSM: A hypoxia imaging agent for PET
-
Laforest, R., Dehdashti, F., Lewis, J. S., and Schwarz, S. W. (2005) Dosimetry of 60/61/62/64Cu-ATSM: A hypoxia imaging agent for PET. Eur. J. Nucl. Med. Mol. Imaging 32, 764-770.
-
(2005)
Eur. J. Nucl. Med. Mol. Imaging
, vol.32
, pp. 764-770
-
-
Laforest, R.1
Dehdashti, F.2
Lewis, J.S.3
Schwarz, S.W.4
-
52
-
-
0038439210
-
Copper-stimulated endocytosis and degradation of the human copper transporter, hCtr1
-
Petris, M. J., Smith, K., Lee, J., and Thiele, D. J. (2003) Copper-stimulated endocytosis and degradation of the human copper transporter, hCtr1. J. Biol. Chem. 278, 9639-9646.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9639-9646
-
-
Petris, M.J.1
Smith, K.2
Lee, J.3
Thiele, D.J.4
-
53
-
-
0037135627
-
Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptake
-
Puig, S., Lee, J., Lau, M., and Thiele, D. J. (2002) Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptake. J. Biol. Chem. 277, 26021-26030.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 26021-26030
-
-
Puig, S.1
Lee, J.2
Lau, M.3
Thiele, D.J.4
-
54
-
-
56949090668
-
Dendritic multishell architectures for drug and dye transport
-
Quadir, M. A., Radowski, M. R., Kratz, F., Licha, K., Hauff, P., and Haag, R. (2008) Dendritic multishell architectures for drug and dye transport. J. Controlled Release 132, 289-294.
-
(2008)
J. Controlled Release
, vol.132
, pp. 289-294
-
-
Quadir, M.A.1
Radowski, M.R.2
Kratz, F.3
Licha, K.4
Hauff, P.5
Haag, R.6
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