Significance of genetic polymorphisms in glutathione S-transferase multigene family and lung cancer risk

International Journal of Occupational Medicine and Environmental Health

Volumn 14, Issue 2, 2001, Pages 99-113

  Reszka, E ^a   Wasowicz W ^a  

^a NOFER INSTITUTE OF OCCUPATIONAL MEDICINE   (Poland)

Author keywords

Epidemiology; Glutathione S tranferase; Lung cancer; Polymorphism; Susceptibility; Xenobiotics

Indexed keywords

GLUTATHIONE TRANSFERASE; ISOENZYME; XENOBIOTIC AGENT;

ALLELE; CANCER RISK; CIGARETTE SMOKING; DETOXIFICATION; DNA ADDUCT; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE DELETION; GENETIC DAMAGE; GENETIC POLYMORPHISM; GENOTOXICITY; GENOTYPE; HUMAN; LUNG CANCER; MULTIGENE FAMILY; REVIEW; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 0034946231     PISSN: 12321087     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (77)

1. Genetic polymorphisms in human xenobiotica metabolizing enzymes as susceptibility factors in toxic response
2. Discovery of a functional polymorphism in human glutathione transferase zeta by expressed sequence tag database analysis
3. Glutathione S-transferase P1 (GSTP1) polymorphism in patients with chronic obstructive pulmonary disease
4. Detection of the GSTM1*0 allele by long polymerase chain reaction
5. Use of site-directed mutagenesis of allele-specific PCR primers to identify the GSTM1 A, GSTM1 B, GSTM1 A,B and GSTM1 null polymorphisms at the glutathione S-transferase, GSTM1 locus
6. The glutathione S-transferases: Polymerase chain reaction studies on the frequency of the GSTM1 0 genotype in patients with pituitary adenomas
7. Genetic polymorphism of CYP2D6, GSTM1 and NAT2 and susceptibility to hematological neoplasias
8. Glutathione S-transferase in human lymphocyte and liver: Role in modulating formation of carcinogen-derived DNA adducts
9. GSTM1 and CYP2D6 genotype frequencies in patients with pituitary tumours: Effects on P53, ras and gsp
10. Polymorphism of glutathione S-transferase M3: Interaction with glutathione S-transferase M1 and lung cancer susceptibility
11. The glutathione S-transferase: Influence of polymorphism on cancer susceptibility
12. Genotypes of glutathione transferase M1 and P1 and their significance for lung DNA adduct levels and cancer risk
13. Polymorphisms of xenobiotic-metabolising enzymes and susceptibility to cancer
14. Lung cancer risk of the GSTM1 null genotype is enhanced in the presence of the GSTP1 mutated genotype in male Japanese smokers
15. Genetic polymorphism of glutathione S-transferase P1 and lung cancer risk
16. Association between glutathione S-transferase π genetic polymorphisms and oral cancer risk
17. Polymorphisms in the glutathione S-transferase class mu and theta genes interact and increase susceptibility to lung cancer in minority populations (Texas, United States)
18. Genetic susceptibility to lung cancer with special emphasis on CYP1A1 and GSTM1: A study on host factors in relation to age at onset, gender and histological cancer types
19. 1 in human lung: Differential cellular distribution and lack of significance of the GSTM1 genetic polymorphism
20. Genetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione S-transferase, and epoxide hydrolase enzymes: Relevance to xenobiotic metabolism and toxicity
21. Glutathione S-transferase mu locus: Use of genotyping and phenotyping assays to assess association with lung cancer susceptibility
22. Human glutathione S-transferase P1 polymorphisms: Relationship to lung tissue enzyme activity and population frequency distribution
23. The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics
24. Glutathione S-transferase in human endometrium: Quantitation and interindividual variability in isoform content
25. Quantitative analysis of interindividual variation of glutathione S-transferase expression in human pancreas and the ambiguity of correlating genotype with phenotype
26. Expression of glutathione S-transferase α, P1-1 and T1-1 in the human gastrointestinal tract
27. Normal bronchial epithelial cell expression of glutathione transferase P1, glutathione transferase M3, and glutathione peroxidase is low in subjects with bronchogenic carcinoma
28. The role of human glutathione S-transferases M1 and T1 in individual susceptibility to bladder cancer
29. Tobacco smoke carcinogens and lung cancer
30. GSTM1 and NAT2 polymorphisms in operable and non-operable lung cancer patients
31. Role of polymorphic GSTM1 and GSTT1 genotypes on NNK-induced genotoxicity
32. Combined glutathione-S-transferase M1 and T1 genetic polymorphism and tacrine hepatotoxicity
33. Haemoglobin adducts of acrylonitrile and ethylene oxide in acrylonitrile workers, dependent on polymorphisms of the glutathione transferases GSTT1 and GSTM1
34. Conjugation of carcinogenes by Θ class glutathione S-transferases: Mechanisms and relevance to variations in human risk
35. Genetic polymorphisms influence variability in benzene metabolism in humans
36. Are individuals with glutathione S-transferase GSTT1 null genotype more susceptible to in vitro oxidative damage?
37. Glutathione S-transferase M1 gene polymorphism and susceptibility to endometriosis in French population
38. Cytochrome P450 2D6 and glutathione S-transferase M1 genotypes and migraine
39. Determination of glutathione S-transferase and polymorphisms in neurological disease
40. Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) genetic polymorphism and susceptibility to gastric and colorectal adenocarcinoma
41. Genetic polymorphism of xenobiotic metabolizing enzymes among Chinese lung cancer patients
42. Polymorphism of glutathione S-transferase M1 and lung cancer risk among African-Americans and Caucasians in Los Angeles County, California
43. Comparison of GSTM polymorphisms and risk for oral cancer between African-Americans and Caucasians
44. Polymorphisms within glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: A case-control study
45. Glutathione S-transferase M1 null genotype is associated with a decreased risk of myocardial infarction
46. Polymorphisms in biotransformation enzymes and the risk for recurrent pregnancy loss
47. Impact of genetic polymorphisms in cytochrome P450 2E1 and glutathione S-transferases M1, T1, and P1 on susceptibility to esophageal cancer among high-risk individuals in China
48. Glutathione S-transferase T1 and M1 genotypes in normal mucosa, transitional mucosa and colorectal adenocarcinoma
49. Genetic susceptibility to chronic obstructive pulmonary disease in Koreans: Combined analysis of polymorphic genotypes for microsomal epoxide hydrolase and glutathione S-transferase M1 and T1
50. Glutathione S-transferase M1 and T1 null genotypes as risk factors for oral leukoplakia in ethnic Indian betel quid/tobacco chewers
51. GSTT1 and GSTM1 null genotypes and the risk of gastric cancer: A case-control study in Chinese population
52. Glutathione S-transferase M1 and T1 polymorphisms: Susceptibility to colon cancer and age of onset
53. Association between glutathione S-transferase M1, P1, and T1, genetic polymorphisms and development of breast cancer
54. The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung
55. A case-control study of cytochrome P450 1A1, glutathione S-transferase M1, cigarette smoking and lung cancer susceptibility (Massachusetts, United States)
56. Glutathione S-transferase M1 (GSTM1) deficiency and lung cancer risk
57. GSTM1, smoking and lung cancer: A case-control study
58. Polymorphisms of the GSTM1 and CYP2D6 genes associated with susceptibility to lung cancer in Chinese
59. Glutathione S-transferase M1 and T1 genotypes and susceptibility to smoking related larynx cancer
60. Effect of vitamin intervention on the relationship between GSTM1, smoking, and lung cancer risk among male smokers
61. Polycyclic aromatic hydrocarbon-DNA adducts in smokers and their relationship to micronutrient levels and the glutathione S-transferase M1 genotype
62. Increased formation of oxidative DNA damage, 8-hydroxy-2′-deoxyguanosine, in human breast cancer tissue and its relationship to GSTP1 and COMT genotypes
63. The influence of GSTM1 and GSTP1 genotypes on the function of sister chromatid exchanges and chromosome aberrations by 1,2:3,4-diepoxybutane
64. Influence of GSTM1 genotypes on anti-BPDE-DNA adduct levels in mononuclear white blood cells of human exposed to PAH
65. Influence of GSTM1, GSTT1, GSTP1, and EPHX polymorphisms on DNA adduct level and HPRT mutant frequency in coke-oven workers
66. The influence of cytochrome P450 1A1 and glutathione S-transferase M1 genotypes on biomarker levels in coke-oven workers
67. Modulation of benzo[a]pyrene diolepoxide-DNA adduct levels in human white blood cells by CYP1A1, GSTM1 and GSTT1 polymorphism
68. Aromatic DNA adducts, micronuclei and genetic polymorphism for CYP1A1 and GSTT1 in chimney sweeps
69. CYP1A1 and GSTM1 polymorphisms affect urinary 1-hydroxypyrene levels after PAH exposure
70. Aromatic DNA adducts in coke-oven workers, in relation to exposure, lifestyle and genetic polymorphism of metabolic enzymes
71. Cytogenetic study of workers exposed to chromium compounds
72. Chromosomal aberrations in humans induced by urban air pollution: Influence of DNA repair and polymorphisms of glutathione S-transferase M1 and N-acetyltransferase 2
73. Cytogenetic and molecular biomonitoring of agricultural workers exposed to pesticides in Brazil
74. Cytogenetic biomonitoring of Spanish greenhouse workers exposed to pesticides and buccal epithelial cells
75. Polymorphisms of the GSTP1 and GSTM1 genes and PAH-DNA adducts in human mononuclear white blood cells
76. The effect of the genetic polymorphisms of CYP1A1, CYP2D6, GSTM1 and GSTP1 on aromatic DNA adduct levels in the population of healthy women
77. Glutathione S-transferase and N-acetyltransferase genotypes and asbestos-associated pulmonary disorders