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Volumn 18, Issue 6, 2009, Pages 516-521

Rottlerin: A multifaced regulator of keratinocyte cell cycle

Author keywords

Cyclin D1; Nuclear factor kappa B; p21; Rottlerin

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C DELTA; PROTEIN P21; ROTTLERIN; THYMIDINE;

EID: 66149145893     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2008.00816.x     Document Type: Article
Times cited : (48)

References (31)
  • 2
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies S P, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 2000: 351: 95-105.
    • (2000) Biochem J , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 3
    • 0035851112 scopus 로고    scopus 로고
    • Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase Cdelta tyrosine phosphorylation
    • Soltoff S P. Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase Cdelta tyrosine phosphorylation. J Biol Chem 2001: 276: 37986-37992.
    • (2001) J Biol Chem , vol.276 , pp. 37986-37992
    • Soltoff, S.P.1
  • 4
    • 34548511124 scopus 로고    scopus 로고
    • Rottlerin: An inappropriate and ineffective inhibitor of PKCdelta
    • Soltoff S P. Rottlerin: An inappropriate and ineffective inhibitor of PKCdelta. Trends Pharmacol Sci 2007: 28: 453-458.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 453-458
    • Soltoff, S.P.1
  • 5
    • 39649095616 scopus 로고    scopus 로고
    • Rottlerin inhibits the nuclear factor kappaB/Cyclin-D1 cascade in MCF-7 breast cancer cells
    • Torricelli C, Fortino V, Capurro E et al. Rottlerin inhibits the nuclear factor kappaB/Cyclin-D1 cascade in MCF-7 breast cancer cells. Life Sci 2008: 82: 638-643.
    • (2008) Life Sci , vol.82 , pp. 638-643
    • Torricelli, C.1    Fortino, V.2    Capurro, E.3
  • 6
    • 14244258610 scopus 로고    scopus 로고
    • Psoriasis pathophysiology: Current concepts of pathogenesis
    • Krueger J G, Bowcock A. Psoriasis pathophysiology: Current concepts of pathogenesis. Ann Rheum Dis 2005: 64 (Suppl. 2): 230-236.
    • (2005) Ann Rheum Dis , vol.64 , Issue.SUPPL. 2 , pp. 230-236
    • Krueger, J.G.1    Bowcock, A.2
  • 7
    • 0028105784 scopus 로고
    • T cells involved in psoriasis vulgaris belong to the TH1 subset
    • Schlaak J F, Buslau M, Jochum W et al. T cells involved in psoriasis vulgaris belong to the TH1 subset. J Invest Dermatol 1994: 102: 145-149.
    • (1994) J Invest Dermatol , vol.102 , pp. 145-149
    • Schlaak, J.F.1    Buslau, M.2    Jochum, W.3
  • 8
    • 0027980960 scopus 로고
    • Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis
    • Detmar M, Brown L F, Claffey K P et al. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis. J Exp Med 1994: 180: 1141-1146.
    • (1994) J Exp Med , vol.180 , pp. 1141-1146
    • Detmar, M.1    Brown, L.F.2    Claffey, K.P.3
  • 9
    • 0036283318 scopus 로고    scopus 로고
    • Mediation of systemic vascular hyperpermeability in severe psoriasis by circulating vascular endothelial growth factor
    • Creamer D, Allen M, Jaggar R et al. Mediation of systemic vascular hyperpermeability in severe psoriasis by circulating vascular endothelial growth factor. Arch Dermatol 2002: 138: 791-796.
    • (2002) Arch Dermatol , vol.138 , pp. 791-796
    • Creamer, D.1    Allen, M.2    Jaggar, R.3
  • 10
    • 34548491621 scopus 로고    scopus 로고
    • Immunopathogenesis of psoriasis
    • Sabat R, Philipp S, Höflich C et al. Immunopathogenesis of psoriasis. Exp Dermatol 2007: 16: 779-798.
    • (2007) Exp Dermatol , vol.16 , pp. 779-798
    • Sabat, R.1    Philipp, S.2    Höflich, C.3
  • 11
    • 34548126864 scopus 로고    scopus 로고
    • Developments in systemic immunomodulatory therapy for psoriasis
    • Berger E M, Gottlieb A B. Developments in systemic immunomodulatory therapy for psoriasis. Curr Opin Pharmacol 2007: 7: 434-444.
    • (2007) Curr Opin Pharmacol , vol.7 , pp. 434-444
    • Berger, E.M.1    Gottlieb, A.B.2
  • 12
    • 21444448471 scopus 로고    scopus 로고
    • Pathway-specific profiling identifies the NF-kappa B-dependent tumor necrosis factor alpha-regulated genes in epidermal keratinocytes
    • Banno T, Gazel A, Blumenberg M. Pathway-specific profiling identifies the NF-kappa B-dependent tumor necrosis factor alpha-regulated genes in epidermal keratinocytes. J Biol Chem 2005: 280: 18973-18980.
    • (2005) J Biol Chem , vol.280 , pp. 18973-18980
    • Banno, T.1    Gazel, A.2    Blumenberg, M.3
  • 13
    • 33846924294 scopus 로고    scopus 로고
    • Nature of cell kinetics in psoriatic epidermis
    • Doger F K, Dikicioglu E, Ergin F et al. Nature of cell kinetics in psoriatic epidermis. J Cutan Pathol 2007: 34: 257-263.
    • (2007) J Cutan Pathol , vol.34 , pp. 257-263
    • Doger, F.K.1    Dikicioglu, E.2    Ergin, F.3
  • 14
    • 20544451475 scopus 로고    scopus 로고
    • Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanercept
    • Lizzul P F, Aphale A, Malaviya R et al. Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanercept. J Invest Dermatol 2005: 124: 1275-1283.
    • (2005) J Invest Dermatol , vol.124 , pp. 1275-1283
    • Lizzul, P.F.1    Aphale, A.2    Malaviya, R.3
  • 15
    • 0033017076 scopus 로고    scopus 로고
    • Epidermal organization and differentiation of HaCaT keratinocytes in organotypic coculture with human dermal fibroblasts
    • Schoop V M, Mirancea N, Fusenig N E. Epidermal organization and differentiation of HaCaT keratinocytes in organotypic coculture with human dermal fibroblasts. J Invest Dermatol 1999: 112: 343-353.
    • (1999) J Invest Dermatol , vol.112 , pp. 343-353
    • Schoop, V.M.1    Mirancea, N.2    Fusenig, N.E.3
  • 16
    • 0027159540 scopus 로고
    • p53 mutations in human immortalized epithelial cell lines
    • Lehman T A, Modali R, Boukamp P et al. p53 mutations in human immortalized epithelial cell lines. Carcinogenesis 1993: 14: 833-839.
    • (1993) Carcinogenesis , vol.14 , pp. 833-839
    • Lehman, T.A.1    Modali, R.2    Boukamp, P.3
  • 17
    • 0041802953 scopus 로고    scopus 로고
    • Rottlerin, an inhibitor of protein kinase Cdelta (PKCdelta), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKCdelta-independent
    • Susarla B T, Robinson M B. Rottlerin, an inhibitor of protein kinase Cdelta (PKCdelta), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKCdelta-independent. J Neurochem 2003: 3: 635-645.
    • (2003) J Neurochem , vol.3 , pp. 635-645
    • Susarla, B.T.1    Robinson, M.B.2
  • 18
    • 1542330957 scopus 로고    scopus 로고
    • Evidence that protein kinase C delta is not required for palmitate-induced cytotoxicity in BRIN-BD11 beta-cells
    • Welters H J, Smith S A, Tadayyon M, Scarpello J H, Morgan N G. Evidence that protein kinase C delta is not required for palmitate-induced cytotoxicity in BRIN-BD11 beta-cells. J Mol Endocrinol 2004: 32: 227-235.
    • (2004) J Mol Endocrinol , vol.32 , pp. 227-235
    • Welters, H.J.1    Smith, S.A.2    Tadayyon, M.3    Scarpello, J.H.4    Morgan, N.G.5
  • 19
    • 0036009909 scopus 로고    scopus 로고
    • NFκB -dependent signaling pathways
    • Li X, Stark G R. NFκB -dependent signaling pathways. Exp Hematol 2002: 30: 285-296.
    • (2002) Exp Hematol , vol.30 , pp. 285-296
    • Li, X.1    Stark, G.R.2
  • 21
    • 0034811889 scopus 로고    scopus 로고
    • Rottlerin induces a transformed phenotype in human keratinocytes
    • Dietrich C, Gumpert N, Heit I et al. Rottlerin induces a transformed phenotype in human keratinocytes. Biochem Biophys Res Commun 2001: 282: 575-579.
    • (2001) Biochem Biophys Res Commun , vol.282 , pp. 575-579
    • Dietrich, C.1    Gumpert, N.2    Heit, I.3
  • 22
    • 0035939845 scopus 로고    scopus 로고
    • Involvement of protein kinase Cdelta in contact-dependent inhibition of growth in human and murine fibroblasts
    • Heit I, Wieser R J, Herget T et al. Involvement of protein kinase Cdelta in contact-dependent inhibition of growth in human and murine fibroblasts. Oncogene 2001: 20: 5143-5154.
    • (2001) Oncogene , vol.20 , pp. 5143-5154
    • Heit, I.1    Wieser, R.J.2    Herget, T.3
  • 23
    • 45149092780 scopus 로고    scopus 로고
    • NF-kappaB and epithelial to mesenchymal transition of cancer
    • Min C, Eddy S F, Sherr D H, Sonenshein G E. NF-kappaB and epithelial to mesenchymal transition of cancer. Cell Biochem 2008: 104: 733-744.
    • (2008) Cell Biochem , vol.104 , pp. 733-744
    • Min, C.1    Eddy, S.F.2    Sherr, D.H.3    Sonenshein, G.E.4
  • 24
    • 0034682037 scopus 로고    scopus 로고
    • Cell-cycle inhibitors: Three families united by a common cause
    • Vidal A, Koff A. Cell-cycle inhibitors: Three families united by a common cause. Gene 2000: 247: 1-15.
    • (2000) Gene , vol.247 , pp. 1-15
    • Vidal, A.1    Koff, A.2
  • 25
    • 0029063745 scopus 로고
    • Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1
    • Luo Y, Hurwitz J, Massagué J. Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1. Nature 1995: 375: 159-161.
    • (1995) Nature , vol.375 , pp. 159-161
    • Luo, Y.1    Hurwitz, J.2    Massagué, J.3
  • 26
    • 9144271919 scopus 로고    scopus 로고
    • Transforming growth factor-beta induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor protein
    • Brown K A, Roberts R L, Arteaga C L, Law B K. Transforming growth factor-beta induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor protein. Breast Cancer Res 2004: 6: R130-R139.
    • (2004) Breast Cancer Res , vol.6
    • Brown, K.A.1    Roberts, R.L.2    Arteaga, C.L.3    Law, B.K.4
  • 27
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • el-Deiry W S, Tokino T, Velculescu V E et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993: 75: 817-825.
    • (1993) Cell , vol.75 , pp. 817-825
    • el-Deiry, W.S.1    Tokino, T.2    Velculescu, V.E.3
  • 28
    • 0034696944 scopus 로고    scopus 로고
    • MAPK-dependent expression of p21(WAF) and p27(kip1) in PMA-induced differentiation of HL60 cells
    • Das D, Pintucci G, Stern A. MAPK-dependent expression of p21(WAF) and p27(kip1) in PMA-induced differentiation of HL60 cells. FEBS Lett 2000: 472: 50-52.
    • (2000) FEBS Lett , vol.472 , pp. 50-52
    • Das, D.1    Pintucci, G.2    Stern, A.3
  • 29
    • 33750536856 scopus 로고    scopus 로고
    • Induction of senescence in diterpene ester-treated melanoma cells via protein kinase C-dependent hyperactivation of the mitogen-activated protein kinase pathway
    • Cozzi S J, Parsons P G, Ogbourne S M et al. Induction of senescence in diterpene ester-treated melanoma cells via protein kinase C-dependent hyperactivation of the mitogen-activated protein kinase pathway. Cancer Res 2006: 66: 10083-10091.
    • (2006) Cancer Res , vol.66 , pp. 10083-10091
    • Cozzi, S.J.1    Parsons, P.G.2    Ogbourne, S.M.3
  • 30
    • 33645073402 scopus 로고    scopus 로고
    • Functional interactions of protein kinase A and C in signalling networks: A recapitulation
    • Maioli E, Torricelli C, Fortino V. Functional interactions of protein kinase A and C in signalling networks: A recapitulation. Cell Mol Life Sci 2006: 63: 637-641.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 637-641
    • Maioli, E.1    Torricelli, C.2    Fortino, V.3
  • 31
    • 34548091298 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase gamma inhibition plays a crucial role in early steps of inflammation by blocking neutrophil recruitment
    • Ferrandi C, Ardissone V, Ferro P et al. Phosphoinositide 3-kinase gamma inhibition plays a crucial role in early steps of inflammation by blocking neutrophil recruitment. J Pharmacol Exp Ther 2007: 322: 923-930.
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 923-930
    • Ferrandi, C.1    Ardissone, V.2    Ferro, P.3


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