-
1
-
-
51349125266
-
DNA vaccination and gene therapy: Optimization and delivery for cancer therapy
-
Bodles-Brakhop, A. M., and R. Draghia-Akli. 2008. DNA vaccination and gene therapy: optimization and delivery for cancer therapy. Expert Rev. Vaccines 7:1085-1101.
-
(2008)
Expert Rev. Vaccines
, vol.7
, pp. 1085-1101
-
-
Bodles-Brakhop, A.M.1
Draghia-Akli, R.2
-
2
-
-
33747765545
-
CD4 T cell-mediated protection from lethal influenza: Perforin and antibody-mediated mechanisms give a one-two punch
-
Brown, D. M., A. M. Dilzer, D. L. Meents, and S. L. Swain. 2006. CD4 T cell-mediated protection from lethal influenza: perforin and antibody-mediated mechanisms give a one-two punch. J. Immunol. 177:2888-2898.
-
(2006)
J. Immunol.
, vol.177
, pp. 2888-2898
-
-
Brown, D.M.1
Dilzer, A.M.2
Meents, D.L.3
Swain, S.L.4
-
3
-
-
48749132801
-
Deaths from bacterial pneumonia during 1918-19 influenza pandemic
-
Brundage, J. F., and G. D. Shanks. 2008. Deaths from bacterial pneumonia during 1918-19 influenza pandemic. Emerg. Infect. Dis. 14:1193-1199.
-
(2008)
Emerg. Infect. Dis.
, vol.14
, pp. 1193-1199
-
-
Brundage, J.F.1
Shanks, G.D.2
-
4
-
-
0031578614
-
Isolation of avian influenza A(H5N1) viruses from humans - Hong Kong, May-December 1997
-
Centers for Disease Control and Prevention
-
Centers for Disease Control and Prevention 1997. Isolation of avian influenza A(H5N1) viruses from humans - Hong Kong, May-December 1997. MMWR Morb. Mortal. Wkly. Rep. 46:1204-1207.
-
(1997)
MMWR Morb. Mortal. Wkly. Rep.
, vol.46
, pp. 1204-1207
-
-
-
5
-
-
28044445881
-
Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells
-
Chan, M. C., C. Y. Cheung, W. H. Chui, S. W. Tsao, J. M. Nicholls, Y. O. Chan, R. W. Chan, H. T. Long, L. L. Poon, Y. Guan, and J. S. Peiris. 2005. Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells. Respir. Res. 6:135.
-
(2005)
Respir. Res.
, vol.6
, pp. 135
-
-
Chan, M.C.1
Cheung, C.Y.2
Chui, W.H.3
Tsao, S.W.4
Nicholls, J.M.5
Chan, Y.O.6
Chan, R.W.7
Long, H.T.8
Poon, L.L.9
Guan, Y.10
Peiris, J.S.11
-
6
-
-
51649100250
-
A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses
-
Chen, M. W., T. J. Cheng, Y. Huang, J. T. Jan, S. H. Ma, A. L. Yu, C. H. Wong, and D. D. Ho. 2008. A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses. Proc. Natl. Acad. Sci. USA 105:13538-13543.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 13538-13543
-
-
Chen, M.W.1
Cheng, T.J.2
Huang, Y.3
Jan, J.T.4
Ma, S.H.5
Yu, A.L.6
Wong, C.H.7
Ho, D.D.8
-
7
-
-
33749511112
-
Fatal outcome of human influenza a (H5N1) is associated with high viral load and hypercytokinemia
-
DOI 10.1038/nm1477, PII NM1477
-
de Jong, M. D., C. P. Simmons, T. T. Thanh, V. M. Hien, G. J. Smith, T. N. Chau, D. M. Hoang, N. V. Chau, T. H. Khanh, V. C. Dong, P. T. Qui, B. V. Cam, D. Q. Ha, Y. Guan, J. S. Peiris, N. T. Chinh, T. T. Hien, and J. Farrar. 2006. Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat. Med. 12:1203-1207. (Pubitemid 44527358)
-
(2006)
Nature Medicine
, vol.12
, Issue.10
, pp. 1203-1207
-
-
De Jong, M.D.1
Simmons, C.P.2
Thanh, T.T.3
Hien, V.M.4
Smith, G.J.D.5
Chau, T.N.B.6
Hoang, D.M.7
Chau, N.V.V.8
Khanh, T.H.9
Dong, V.C.10
Qui, P.T.11
Cam, B.V.12
Ha, D.Q.13
Guan, Y.14
Peiris, J.S.M.15
Chinh, N.T.16
Hien, T.T.17
Farrar, J.18
-
8
-
-
45149129921
-
A clinical trial of a whole-virus H5N1 vaccine derived from cell culture
-
Ehrlich, H. J., M. Muller, H. M. Oh, P. A. Tambyah, C. Joukhadar, E. Montomoli, D. Fisher, G. Berezuk, S. Fritsch, A. Low-Baselli, N. Vartian, R. Bobrovsky, B. G. Pavlova, E. M. Pollabauer, O. Kistner, and P. N. Barrett. 2008. A clinical trial of a whole-virus H5N1 vaccine derived from cell culture. N. Engl. J. Med. 358:2573-2584.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 2573-2584
-
-
Ehrlich, H.J.1
Muller, M.2
Oh, H.M.3
Tambyah, P.A.4
Joukhadar, C.5
Montomoli, E.6
Fisher, D.7
Berezuk, G.8
Fritsch, S.9
Low-Baselli, A.10
Vartian, N.11
Bobrovsky, R.12
Pavlova, B.G.13
Pollabauer, E.M.14
Kistner, O.15
Barrett, P.N.16
-
9
-
-
29744438219
-
Prior H1N1 influenza infection and susceptibility of Cleveland Family Study participants during the H2N2 pandemic of 1957: An experiment of nature
-
DOI 10.1086/498980
-
Epstein, S. L. 2006. Prior H1N1 influenza infection and susceptibility of Cleveland Family Study participants during the H2N2 pandemic of 1957: an experiment of nature. J. Infect. Dis. 193:49-53. (Pubitemid 43032498)
-
(2006)
Journal of Infectious Diseases
, vol.193
, Issue.1
, pp. 49-53
-
-
Epstein, S.L.1
-
10
-
-
27644544183
-
Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein
-
Epstein, S. L., W. P. Kong, J. A. Misplon, C. Y. Lo, T. M. Tumpey, L. Xu, and G. J. Nabel. 2005. Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein. Vaccine 23:5404-5410.
-
(2005)
Vaccine
, vol.23
, pp. 5404-5410
-
-
Epstein, S.L.1
Kong, W.P.2
Misplon, J.A.3
Lo, C.Y.4
Tumpey, T.M.5
Xu, L.6
Nabel, G.J.7
-
11
-
-
37549037877
-
Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques
-
Hirao, L. A., L. Wu, A. S. Khan, A. Satishchandran, R. Draghia-Akli, and D. B. Weiner. 2008. Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques. Vaccine 26:440-448.
-
(2008)
Vaccine
, vol.26
, pp. 440-448
-
-
Hirao, L.A.1
Wu, L.2
Khan, A.S.3
Satishchandran, A.4
Draghia-Akli, R.5
Weiner, D.B.6
-
12
-
-
37849044516
-
A vaccine prepared from a non-pathogenic H5N1 avian influenza virus strain confers protective immunity against highly pathogenic avian influenza virus infection in cynomolgus macaques
-
Itoh, Y., H. Ozaki, H. Tsuchiya, K. Okamoto, R. Torii, Y. Sakoda, Y. Kawaoka, K. Ogasawara, and H. Kida. 2008. A vaccine prepared from a non-pathogenic H5N1 avian influenza virus strain confers protective immunity against highly pathogenic avian influenza virus infection in cynomolgus macaques. Vaccine 26:562-572.
-
(2008)
Vaccine
, vol.26
, pp. 562-572
-
-
Itoh, Y.1
Ozaki, H.2
Tsuchiya, H.3
Okamoto, K.4
Torii, R.5
Sakoda, Y.6
Kawaoka, Y.7
Ogasawara, K.8
Kida, H.9
-
13
-
-
33749514992
-
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus
-
Kash, J. C., T. M. Tumpey, S. C. Proll, V. Carter, O. Perwitasari, M. J. Thomas, C. F. Basler, P. Palese, J. K. Taubenberger, A. Garcia-Sastre, D. E. Swayne, and M. G. Katze. 2006. Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus. Nature 443:578-581.
-
(2006)
Nature
, vol.443
, pp. 578-581
-
-
Kash, J.C.1
Tumpey, T.M.2
Proll, S.C.3
Carter, V.4
Perwitasari, O.5
Thomas, M.J.6
Basler, C.F.7
Palese, P.8
Taubenberger, J.K.9
Garcia-Sastre, A.10
Swayne, D.E.11
Katze, M.G.12
-
14
-
-
33846265834
-
Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus
-
Kobasa, D., S. M. Jones, K. Shinya, J. C. Kash, J. Copps, H. Ebihara, Y. Hatta, J. H. Kim, P. Halfmann, M. Hatta, F. Feldmann, J. B. Alimonti, L. Fernando, Y. Li, M. G. Katze, H. Feldmann, and Y. Kawaoka. 2007. Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus. Nature 445:319-323.
-
(2007)
Nature
, vol.445
, pp. 319-323
-
-
Kobasa, D.1
Jones, S.M.2
Shinya, K.3
Kash, J.C.4
Copps, J.5
Ebihara, H.6
Hatta, Y.7
Kim, J.H.8
Halfmann, P.9
Hatta, M.10
Feldmann, F.11
Alimonti, J.B.12
Fernando, L.13
Li, Y.14
Katze, M.G.15
Feldmann, H.16
Kawaoka, Y.17
-
15
-
-
33845205893
-
Primary influenza A virus infection induces cross-protective immunity against a lethal infection with a heterosubtypic virus strain in mice
-
Kreijtz, J. H., R. Bodewes, G. van Amerongen, T. Kuiken, R. A. Fouchier, A. D. Osterhaus, and G. F. Rimmelzwaan. 2007. Primary influenza A virus infection induces cross-protective immunity against a lethal infection with a heterosubtypic virus strain in mice. Vaccine 25:612-620.
-
(2007)
Vaccine
, vol.25
, pp. 612-620
-
-
Kreijtz, J.H.1
Bodewes, R.2
Van Amerongen, G.3
Kuiken, T.4
Fouchier, R.A.5
Osterhaus, A.D.6
Rimmelzwaan, G.F.7
-
16
-
-
0038486953
-
Pathology of human influenza A (H5N1) virus infection in cynomolgus macaques (Macaca fascicularis)
-
Kuiken, T., G. F. Rimmelzwaan, G. Van Amerongen, and A. D. Osterhaus. 2003. Pathology of human influenza A (H5N1) virus infection in cynomolgus macaques (Macaca fascicularis). Vet. Pathol. 40:304-310.
-
(2003)
Vet. Pathol.
, vol.40
, pp. 304-310
-
-
Kuiken, T.1
Rimmelzwaan, G.F.2
Van Amerongen, G.3
Osterhaus, A.D.4
-
17
-
-
21244447927
-
Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help
-
Kutzler, M. A., T. M. Robinson, M. A. Chattergoon, D. K. Choo, A. Y. Choo, P. Y. Choe, M. P. Ramanathan, R. Parkinson, S. Kudchodkar, Y. Tamura, M. Sidhu, V. Roopchand, J. J. Kim, G. N. Pavlakis, B. K. Felber, T. A. Waldmann, J. D. Boyer, and D. B. Weiner. 2005. Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help. J. Immunol. 175:112-123. (Pubitemid 40884307)
-
(2005)
Journal of Immunology
, vol.175
, Issue.1
, pp. 112-123
-
-
Kutzler, M.A.1
Robinson, T.M.2
Chattergoon, M.A.3
Choo, D.K.4
Choo, A.Y.5
Choe, P.Y.6
Ramanathan, M.P.7
Parkinson, R.8
Kudchodkar, S.9
Tamura, Y.10
Sidhu, M.11
Roopchand, V.12
Kim, J.J.13
Pavlakis, G.N.14
Felber, B.K.15
Waldmann, T.A.16
Boyer, J.D.17
Weiner, D.B.18
-
18
-
-
49649094496
-
Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens
-
Laddy, D. J., J. Yan, M. Kutzler, D. Kobasa, G. P. Kobinger, A. S. Khan, J. Greenhouse, N. Y. Sardesai, R. Draghia-Akli, and D. B. Weiner. 2008. Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens. PLoS ONE 3:e2517.
-
(2008)
PLoS ONE
, vol.3
-
-
Laddy, D.J.1
Yan, J.2
Kutzler, M.3
Kobasa, D.4
Kobinger, G.P.5
Khan, A.S.6
Greenhouse, J.7
Sardesai, N.Y.8
Draghia-Akli, R.9
Weiner, D.B.10
-
19
-
-
50949104571
-
An adjuvanted, low-dose, pandemic influenza A (H5N1) vaccine candidate is safe, immunogenic, and induces cross-reactive immune responses in healthy adults
-
Levie, K., I. Leroux-Roels, K. Hoppenbrouwers, A. D. Kervyn, C. Vandermeulen, S. Forgus, G. Leroux-Roels, S. Pichon, and I. Kusters. 2008. An adjuvanted, low-dose, pandemic influenza A (H5N1) vaccine candidate is safe, immunogenic, and induces cross-reactive immune responses in healthy adults. J. Infect. Dis. 198:642-649.
-
(2008)
J. Infect. Dis.
, vol.198
, pp. 642-649
-
-
Levie, K.1
Leroux-Roels, I.2
Hoppenbrouwers, K.3
Kervyn, A.D.4
Vandermeulen, C.5
Forgus, S.6
Leroux-Roels, G.7
Pichon, S.8
Kusters, I.9
-
20
-
-
33748447102
-
Safety and immunogenicity of an inactivated adjuvanted whole-virion influenza A (H5N1) vaccine: A phase I randomised controlled trial
-
Lin, J., J. Zhang, X. Dong, H. Fang, J. Chen, N. Su, Q. Gao, Z. Zhang, Y. Liu, Z. Wang, M. Yang, R. Sun, C. Li, S. Lin, M. Ji, Y. Liu, X. Wang, J. Wood, Z. Feng, Y. Wang, and W. Yin. 2006. Safety and immunogenicity of an inactivated adjuvanted whole-virion influenza A (H5N1) vaccine: a phase I randomised controlled trial. Lancet 368:991-997.
-
(2006)
Lancet
, vol.368
, pp. 991-997
-
-
Lin, J.1
Zhang, J.2
Dong, X.3
Fang, H.4
Chen, J.5
Su, N.6
Gao, Q.7
Zhang, Z.8
Liu, Y.9
Wang, Z.10
Yang, M.11
Sun, R.12
Li, C.13
Lin, S.14
Ji, M.15
Liu, Y.16
Wang, X.17
Wood, J.18
Feng, Z.19
Wang, Y.20
Yin, W.21
more..
-
21
-
-
33646468500
-
T cell responses are better correlates of vaccine protection in the elderly
-
McElhaney, J. E., D. Xie, W. D. Hager, M. B. Barry, Y. Wang, A. Kleppinger, C. Ewen, K. P. Kane, and R. C. Bleackley. 2006. T cell responses are better correlates of vaccine protection in the elderly. J. Immunol. 176:6333-6339.
-
(2006)
J. Immunol.
, vol.176
, pp. 6333-6339
-
-
McElhaney, J.E.1
Xie, D.2
Hager, W.D.3
Barry, M.B.4
Wang, Y.5
Kleppinger, A.6
Ewen, C.7
Kane, K.P.8
Bleackley, R.C.9
-
22
-
-
33846219152
-
Priming with cold-adapted influenza A does not prevent infection but elicits long-lived protection against supralethal challenge with heterosubtypic virus
-
Powell, T. J., T. Strutt, J. Reome, J. A. Hollenbaugh, A. D. Roberts, D. L. Woodland, S. L. Swain, and R. W. Dutton. 2007. Priming with cold-adapted influenza A does not prevent infection but elicits long-lived protection against supralethal challenge with heterosubtypic virus. J. Immunol. 178:1030-1038. (Pubitemid 46095176)
-
(2007)
Journal of Immunology
, vol.178
, Issue.2
, pp. 1030-1038
-
-
Powell, T.J.1
Strutt, T.2
Reome, J.3
Hollenbaugh, J.A.4
Roberts, A.D.5
Woodland, D.L.6
Swain, S.L.7
Dutton, R.W.8
-
23
-
-
0034979498
-
Pathogenesis of influenza a (H5N1) virus infection in a primate model
-
DOI 10.1128/JVI.75.14.6687-6691.2001
-
Rimmelzwaan, G. F., T. Kuiken, G. van Amerongen, T. M. Bestebroer, R. A. Fouchier, and A. D. Osterhaus. 2001. Pathogenesis of influenza A (H5N1) virus infection in a primate model. J. Virol. 75:6687-6691. (Pubitemid 32578188)
-
(2001)
Journal of Virology
, vol.75
, Issue.14
, pp. 6687-6691
-
-
Rimmelzwaan, G.F.1
Kuiken, T.2
Van Amerongen, G.3
Bestebroer, T.M.4
Fouchier, R.A.M.5
Osterhaus, A.D.M.E.6
-
24
-
-
0033041241
-
Detection of antibody to avian influenza A (H5N1) virus in human serum by using a combination of serologic assays
-
Rowe, T., R. A. Abernathy, J. Hu-Primmer, W. W. Thompson, X. Lu, W. Lim, K. Fukuda, N. J. Cox, and J. M. Katz. 1999. Detection of antibody to avian influenza A (H5N1) virus in human serum by using a combination of serologic assays. J. Clin. Microbiol. 37:937-943. (Pubitemid 29140593)
-
(1999)
Journal of Clinical Microbiology
, vol.37
, Issue.4
, pp. 937-943
-
-
Rowe, T.1
Abernathy, R.A.2
Hu-Primmer, J.3
Thompson, W.W.4
Lu, X.5
Lim, W.6
Fukuda, K.7
Cox, N.J.8
Katz, J.M.9
-
25
-
-
39749159136
-
Vaccination of macaques with adjuvanted formalin-inactivated influenza A virus (H5N1) vaccines: Protection against H5N1 challenge without disease enhancement
-
Ruat, C., C. Caillet, A. Bidaut, J. Simon, and A. D. Osterhaus. 2008. Vaccination of macaques with adjuvanted formalin-inactivated influenza A virus (H5N1) vaccines: protection against H5N1 challenge without disease enhancement. J. Virol. 82:2565-2569.
-
(2008)
J. Virol.
, vol.82
, pp. 2565-2569
-
-
Ruat, C.1
Caillet, C.2
Bidaut, A.3
Simon, J.4
Osterhaus, A.D.5
-
26
-
-
34247275658
-
Comparison of neutralising antibody assays for detection of antibody to influenza A/H3N2 viruses: An international collaborative study
-
Stephenson, I., R. G. Das, J. M. Wood, and J. M. Katz. 2007. Comparison of neutralising antibody assays for detection of antibody to influenza A/H3N2 viruses: an international collaborative study. Vaccine 25:4056-4063.
-
(2007)
Vaccine
, vol.25
, pp. 4056-4063
-
-
Stephenson, I.1
Das, R.G.2
Wood, J.M.3
Katz, J.M.4
-
27
-
-
2442599892
-
Detection of anti-H5 responses in human sera by HI using horse erythrocytes following MF59-adjuvanted influenza A/Duck/Singapore/97 vaccine
-
DOI 10.1016/j.virusres.2004.02.019, PII S0168170204001182
-
Stephenson, I., J. M. Wood, K. G. Nicholson, A. Charlett, and M. C. Zambon. 2004. Detection of anti-H5 responses in human sera by HI using horse erythrocytes following MF59-adjuvanted influenza A/Duck/Singapore/97 vaccine. Virus Res. 103:91-95. (Pubitemid 38649066)
-
(2004)
Virus Research
, vol.103
, Issue.1-2
, pp. 91-95
-
-
Stephenson, I.1
Wood, J.M.2
Nicholson, K.G.3
Charlett, A.4
Zambon, M.C.5
-
28
-
-
33645972581
-
H5N1 virus attachment to lower respiratory tract
-
van Riel, D., V. J. Munster, E. de Wit, G. F. Rimmelzwaan, R. A. Fouchier, A. D. Osterhaus, and T. Kuiken. 2006. H5N1 virus attachment to lower respiratory tract. Science 312:399.
-
(2006)
Science
, vol.312
, pp. 399
-
-
Van Riel, D.1
Munster, V.J.2
De Wit, E.3
Rimmelzwaan, G.F.4
Fouchier, R.A.5
Osterhaus, A.D.6
Kuiken, T.7
-
29
-
-
35348888890
-
Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals
-
DOI 10.2353/ajpath.2007.070248
-
van Riel, D., V. J. Munster, E. de Wit, G. F. Rimmelzwaan, R. A. Fouchier, A. D. Osterhaus, and T. Kuiken. 2007. Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals. Am. J. Pathol. 171:1215-1223. (Pubitemid 47582895)
-
(2007)
American Journal of Pathology
, vol.171
, Issue.4
, pp. 1215-1223
-
-
Van Riel, D.1
Munster, V.J.2
De Wit, E.3
Rimmelzwaan, G.F.4
Fouchier, R.A.M.5
Osterhaus, A.D.M.E.6
Kuiken, T.7
|