-
1
-
-
0032491319
-
2 and PIP as determinants for ATP inhibition of K(ATP) channels
-
Baukrowitz T, Schulte U, Oliver D, Herlitze S, Krauter T, Tucker SJ, Ruppersberg JP, Fakler B. PIP2 and PIP as determinants for ATP inhibition of KATP channels. Science 282: 1141-1144, 1998. (Pubitemid 28516246)
-
(1998)
Science
, vol.282
, Issue.5391
, pp. 1141-1144
-
-
Baukrowitz, T.1
Schulte, U.2
Oliver, D.3
Herlitze, S.4
Krauter, T.5
Tucker, S.J.6
Ruppersberg, J.P.7
Fakler, B.8
-
2
-
-
0037646521
-
A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes
-
DOI 10.1074/jbc.M212868200
-
Beeton C, Wulff H, Singh S, Botsko S, Crossley G, Gutman GA, Cahalan MD, Pennington M, Chandy KG. A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes. J Biol Chem 278: 9928-9937, 2003. (Pubitemid 36800497)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.11
, pp. 9928-9937
-
-
Beeton, C.1
Wulff, H.2
Singh, S.3
Botsko, S.4
Crossley, G.5
Gutman, G.A.6
Cahalan, M.D.7
Pennington, M.8
Chandy, K.G.9
-
3
-
-
0035824896
-
+ channel activity is regulated by changes in phosphatidyl inositol 4,5-bisphosphate
-
Bian J, Cui J, McDonald TV. HERG K(+) channel activity is regulated by changes in phosphatidyl inositol 4,5-bisphosphate. Circ Res 89: 1168-1176, 2001. (Pubitemid 34627875)
-
(2001)
Circulation Research
, vol.89
, Issue.12
, pp. 1168-1176
-
-
Bian, J.1
Cui, J.2
McDonald, T.V.3
-
7
-
-
34548660057
-
2 and other membrane phospholipids
-
DOI 10.1007/s00424-007-0250-2, Phosphoinositide control of ion channel activity
-
Chemin J, Patel AJ, Duprat F, Sachs F, Lazdunski M, Honore E. Upand down-regulation of the mechano-gated K(2P) channel TREK-1 by PIP (2) and other membrane phospholipids. Pflügers Arch 455: 97-103, 2007. (Pubitemid 47403975)
-
(2007)
Pflugers Archiv European Journal of Physiology
, vol.455
, Issue.1
, pp. 97-103
-
-
Chemin, J.1
Patel, A.J.2
Duprat, F.3
Sachs, F.4
Lazdunski, M.5
Honore, E.6
-
8
-
-
57149103679
-
Structural determinants of Kvbeta1.3-induced channel inactivation: A hairpin modulated by PIP2
-
Decher N, Gonzalez T, Streit AK, Sachse FB, Renigunta V, Soom M, Heinemann SH, Daut J, Sanguinetti MC. Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2. EMBO J 27: 3164-3174, 2008.
-
(2008)
EMBO J
, vol.27
, pp. 3164-3174
-
-
Decher, N.1
Gonzalez, T.2
Streit, A.K.3
Sachse, F.B.4
Renigunta, V.5
Soom, M.6
Heinemann, S.H.7
Daut, J.8
Sanguinetti, M.C.9
-
9
-
-
33845896298
-
PI(3)Kγ has an important context-dependent role in neutrophil chemokinesis
-
DOI 10.1038/ncb1517, PII NCB1517
-
Ferguson GJ, Milne L, Kulkarni S, Sasaki T, Walker S, Andrews S, Crabbe T, Finan P, Jones G, Jackson S, Camps M, Rommel C, Wymann M, Hirsch E, Hawkins P, Stephens L. PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis. Nat Cell Biol 9: 86-91, 2007. (Pubitemid 46024201)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.1
, pp. 86-91
-
-
Ferguson, G.J.1
Milne, L.2
Kulkarni, S.3
Sasaki, T.4
Walker, S.5
Andrews, S.6
Crabbe, T.7
Finan, P.8
Jones, G.9
Jackson, S.10
Camps, M.11
Rommel, C.12
Wymann, M.13
Hirsch, E.14
Hawkins, P.15
Stephens, L.16
-
10
-
-
33845873342
-
3 and directed migration
-
DOI 10.1038/ncb0107-15, PII NCB0107-15
-
Franca-Koh J, Kamimura Y, Devreotes PN. Leading-edge research: PtdIns(3,4,5)P3 and directed migration. Nat Cell Biol 9: 15-17, 2007. (Pubitemid 46024189)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.1
, pp. 15-17
-
-
Franca-Koh, J.1
Kamimura, Y.2
Devreotes, P.N.3
-
11
-
-
34250868904
-
Regulation of cardiac ion channels via non-genomic action of sex steroid hormones: Implication for the gender difference in cardiac arrhythmias
-
DOI 10.1016/j.pharmthera.2007.04.008, PII S0163725807000873
-
Furukawa T, Kurokawa J. Regulation of cardiac ion channels via non-genomic action of sex steroid hormones: implication for the gender difference in cardiac arrhythmias. Pharmacol Ther 115: 106-115, 2007. (Pubitemid 46990555)
-
(2007)
Pharmacology and Therapeutics
, vol.115
, Issue.1
, pp. 106-115
-
-
Furukawa, T.1
Kurokawa, J.2
-
12
-
-
0034711234
-
Up-regulation of the IKCa1 potassium channel during T-cell activation: Molecular mechanism and functional consequences
-
DOI 10.1074/jbc.M003941200
-
Ghanshani S, Wulff H, Miller MJ, Rohm H, Neben A, Gutman GA, Cahalan MD, Chandy KG. Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences. J Biol Chem 275: 37137-37149, 2000. (Pubitemid 32002132)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.47
, pp. 37137-37149
-
-
Ghanshani, S.1
Wulff, H.2
Miller, M.J.3
Rohm, H.4
Neben, A.5
Gutman, G.A.6
Cahalan, M.D.7
Chandy, K.G.8
-
13
-
-
14944338800
-
Stromal cell-derived factor-1α directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells
-
DOI 10.1111/j.1471-4159.2005.03083.x
-
Guyon A, Rovere C, Cervantes A, Allaeys I, Nahon JL. Stromal cell-derived factor-1alpha directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells. J Neurochem 93:963-973, 2005. (Pubitemid 40695755)
-
(2005)
Journal of Neurochemistry
, vol.93
, Issue.4
, pp. 963-973
-
-
Guyon, A.1
Rovere, C.2
Cervantes, A.3
Allaeys, I.4
Nahon, J.-L.5
-
14
-
-
0019441262
-
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
-
DOI 10.1007/BF00656997
-
Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 391: 85-100, 1981. (Pubitemid 11012976)
-
(1981)
Pflugers Archiv European Journal of Physiology
, vol.391
, Issue.2
, pp. 85-100
-
-
Hamill, O.P.1
Marty, A.2
Neher, E.3
-
15
-
-
0030951463
-
Margatoxin binds to a homomultimer of K(v)1.3 channels in Jurkat cells. Comparison with K(v)1.3 expressed in CHO cells
-
DOI 10.1021/bi962351p
-
Helms LM, Felix JP, Bugianesi RM, Garcia ML, Stevens S, Leonard RJ, Knaus HG, Koch R, Wanner SG, Kaczorowski GJ, Slaughter RS. Margatoxin binds to a homomultimer of K(V)1.3 channels in Jurkat cells. Comparison with K(V)1.3 expressed in CHO cells. Biochemistry 36: 3737-3744, 1997. (Pubitemid 27143530)
-
(1997)
Biochemistry
, vol.36
, Issue.12
, pp. 3737-3744
-
-
Helms, L.M.H.1
Felix, J.P.2
Bugianesi, R.M.3
Garcia, M.L.4
Stevens, S.5
Leonard, R.J.6
Knaus, H.-G.7
Koch, R.8
Wanner, S.G.9
Kaczorowski, G.J.10
Slaughter, R.S.11
-
16
-
-
34447291088
-
Ryanodine receptor type 2 deficiency changes excitation-contraction coupling and membrane potential in urinary bladder smooth muscle
-
DOI 10.1113/jphysiol.2007.130302
-
Hotta S, Morimura K, Ohya S, Muraki K, Takeshima H, Imaizumi Y. Ryanodine receptor type 2 deficiency changes excitation-contraction coupling and membrane potential in urinary bladder smooth muscle. J Physiol 582: 489-506, 2007. (Pubitemid 47040540)
-
(2007)
Journal of Physiology
, vol.582
, Issue.2
, pp. 489-506
-
-
Hotta, S.1
Morimura, K.2
Ohya, S.3
Muraki, K.4
Takeshima, H.5
Imaizumi, Y.6
-
17
-
-
36549039931
-
Complex roles of PIP2 in the regulation of ion channels and transporters
-
Huang CL. Complex roles of PIP2 in the regulation of ion channels and transporters. Am J Physiol Renal Physiol 293: F1761-F1765, 2007.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Huang, C.L.1
-
18
-
-
0032546013
-
2 and its stabilization by Gβγ
-
DOI 10.1038/35882
-
Huang CL, Feng S, Hilgemann DW. Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma. Nature 391: 803-806, 1998. (Pubitemid 28099680)
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 803-806
-
-
Huang, C.-L.1
Feng, S.2
Hilgemann, D.W.3
-
20
-
-
0038578823
-
3
-
DOI 10.1034/j.1600-065X.2003.00008.x
-
Kane LP, Weiss A. The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3. Immunol Rev 192: 7-20, 2003. (Pubitemid 36613319)
-
(2003)
Immunological Reviews
, vol.192
, pp. 7-20
-
-
Kane, L.P.1
Weiss, A.2
-
21
-
-
2342545918
-
Immune and nervous system CXCL12 and CXCR4: Parallel roles in patterning and plasticity
-
Klein RS, Rubin JB. Immune and nervous system CXCL12 and CXCR4: parallel roles in patterning and plasticity. Trends Immunol 25: 306-314, 2004.
-
(2004)
Trends Immunol
, vol.25
, pp. 306-314
-
-
Klein, R.S.1
Rubin, J.B.2
-
22
-
-
0029016295
-
Intracellular and extracellular amino acids that influence C-type inactivation and its modulation in a voltage-dependent potassium channel
-
Kupper J, Bowlby MR, Marom S, Levitan IB. Intracellular and extracellular amino acids that influence C-type inactivation and its modulation in a voltage-dependent potassium channel. Pflügers Arch 430: 1-11, 1995.
-
(1995)
Pflügers Arch
, vol.430
, pp. 1-11
-
-
Kupper, J.1
Bowlby, M.R.2
Marom, S.3
Levitan, I.B.4
-
23
-
-
0142105405
-
+ channels
-
DOI 10.1093/emboj/cdg526
-
Loussouarn G, Park KH, Bellocq C, Baro I, Charpentier F, Escande D. Phosphatidylinositol-4,5-bisphosphate, PIP2, controls KCNQ1/KCNE1 voltage-gated potassium channels: a functional homology between voltage-gated and inward rectifier K+ channels. EMBO J 22: 5412-5421, 2003. (Pubitemid 37279951)
-
(2003)
EMBO Journal
, vol.22
, Issue.20
, pp. 5412-5421
-
-
Loussouarn, G.1
Park, K.-H.2
Bellocq, C.3
Baro, I.4
Charpentier, F.5
Escande, D.6
-
24
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell 129: 1261-1274, 2007.
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
25
-
-
47749134125
-
Molecular mechanisms for Kv1.3 potassium channel current inhibition by CD3/CD28 stimulation in Jurkat T cells
-
Matsushita Y, Ohya S, Itoda H, Kimura T, Suzuki Y, Yamamura S, Imaizumi Y. Molecular mechanisms for Kv1.3 potassium channel current inhibition by CD3/CD28 stimulation in Jurkat T cells. Biochem Biophys Res Commun 374: 152-157, 2008.
-
(2008)
Biochem Biophys Res Commun
, vol.374
, pp. 152-157
-
-
Matsushita, Y.1
Ohya, S.2
Itoda, H.3
Kimura, T.4
Suzuki, Y.5
Yamamura, S.6
Imaizumi, Y.7
-
27
-
-
0036082665
-
2 and proteins: Interactions, organization, and information flow
-
DOI 10.1146/annurev.biophys.31.082901.134259
-
McLaughlin S, Wang J, Gambhir A, Murray D. PIP(2) and proteins: interactions, organization, and information flow. Annu Rev Biophys Biomol Struct 31: 151-175, 2002. (Pubitemid 34666829)
-
(2002)
Annual Review of Biophysics and Biomolecular Structure
, vol.31
, pp. 151-175
-
-
McLaughlin, S.1
Wang, J.2
Gambhir, A.3
Murray, D.4
-
29
-
-
55549104701
-
Transient receptor potential channels meet phosphoinositides
-
Nilius B, Owsianik G, Voets T. Transient receptor potential channels meet phosphoinositides. EMBO J 27: 2809-2816, 2008.
-
(2008)
EMBO J
, vol.27
, pp. 2809-2816
-
-
Nilius, B.1
Owsianik, G.2
Voets, T.3
-
30
-
-
0036184216
-
Regulation of calcium currents by chemokines and their receptors
-
DOI 10.1016/S0165-5728(01)00485-4, PII S0165572801004854
-
Oh SB, Endoh T, Simen AA, Ren D, Miller RJ. Regulation of calcium currents by chemokines and their receptors. J Neuroimmunol 123: 66-75, 2002. (Pubitemid 34195608)
-
(2002)
Journal of Neuroimmunology
, vol.123
, Issue.1-2
, pp. 66-75
-
-
Oh, S.B.1
Endoh, T.2
Simen, A.A.3
Ren, D.4
Miller, R.J.5
-
32
-
-
33947527297
-
Signalling to suit function: Tailoring phosphoinositide 3-kinase during T-cell activation
-
Parry RV, Riley JL, Ward SG. Signalling to suit function: tailoring phosphoinositide 3-kinase during T-cell activation. Trends Immunol 28: 161-168, 2007.
-
(2007)
Trends Immunol
, vol.28
, pp. 161-168
-
-
Parry, R.V.1
Riley, J.L.2
Ward, S.G.3
-
33
-
-
0034332904
-
Leukocytes navigate by compass: Roles of PI3Kgamma and its lipid products
-
Rickert P, Weiner OD, Wang F, Bourne HR, Servant G. Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products. Trends Cell Biol 10: 466-473, 2000.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 466-473
-
-
Rickert, P.1
Weiner, O.D.2
Wang, F.3
Bourne, H.R.4
Servant, G.5
-
34
-
-
0036092076
-
2 hydrolysis
-
DOI 10.1038/ncb781
-
Runnels LW, Yue L, Clapham DE. The TRPM7 channel is inactivated by PIP(2) hydrolysis. Nat Cell Biol 4: 329-336, 2002. (Pubitemid 34521027)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.5
, pp. 329-336
-
-
Runnels, L.W.1
Yue, L.2
Clapham, D.E.3
-
35
-
-
0036607859
-
Intrathymic T-cell migration: A combinatorial interplay of extracellular matrix and chemokines?
-
DOI 10.1016/S1471-4906(02)02224-X, PII S147149060202224X
-
Savino W, Mendes-da-Cruz DA, Silva JS, Dardenne M, Cotta-de-Almeida V. Intrathymic T-cell migration: a combinatorial interplay of extracellular matrix and chemokines? Trends Immunol 23: 305-313, 2002. (Pubitemid 34628774)
-
(2002)
Trends in Immunology
, vol.23
, Issue.6
, pp. 305-313
-
-
Savino, W.1
Mendes-Da-Cruz, D.A.2
Silva, J.S.3
Dardenne, M.4
Cotta-De-Almeida, V.5
-
36
-
-
0034635513
-
Polarization of chemoattractant receptor signaling during neutrophil chemotaxis
-
DOI 10.1126/science.287.5455.1037
-
Servant G, Weiner OD, Herzmark P, Balla T, Sedat JW, Bourne HR. Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science 287: 1037-1040, 2000. (Pubitemid 30094359)
-
(2000)
Science
, vol.287
, Issue.5455
, pp. 1037-1040
-
-
Servant, G.1
Weiner, O.D.2
Herzmark, P.3
Balla, T.4
Sedat, J.W.5
Bourne, H.R.6
-
37
-
-
0033486065
-
The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes
-
Sotsios Y, Whittaker GC, Westwick J, Ward SG. The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes. J Immunol 163: 5954-5963, 1999.
-
(1999)
J Immunol
, vol.163
, pp. 5954-5963
-
-
Sotsios, Y.1
Whittaker, G.C.2
Westwick, J.3
Ward, S.G.4
-
38
-
-
34248220063
-
CXC chemokine receptor 4 regulates neuronal migration and axonal pathfinding in the developing nervous system: Implications for neuronal regeneration in the adult brain
-
DOI 10.1677/JME-06-0032
-
Stumm R, Hollt V. CXC chemokine receptor 4 regulates neuronal migration and axonal pathfinding in the developing nervous system: implications for neuronal regeneration in the adult brain. J Mol Endocrinol 38: 377-382, 2007. (Pubitemid 46723253)
-
(2007)
Journal of Molecular Endocrinology
, vol.38
, Issue.3-4
, pp. 377-382
-
-
Stumm, R.1
Hollt, V.2
-
39
-
-
48249116482
-
PIP2 is a necessary cofactor for ion channel function: How and why?
-
Suh BC, Hille B. PIP2 is a necessary cofactor for ion channel function: how and why? Annu Rev Biophys 37: 175-195, 2008.
-
(2008)
Annu Rev Biophys
, vol.37
, pp. 175-195
-
-
Suh, B.C.1
Hille, B.2
-
40
-
-
33748635840
-
The chemokine receptor CXCR4 as a therapeutic target for several diseases
-
DOI 10.2174/138955706778195135
-
Tamamura H, Tsutsumi H, Fujii N. The chemokine receptor CXCR4 as a therapeutic target for several diseases. Mini Rev Med Chem 6: 989-995, 2006. (Pubitemid 44383185)
-
(2006)
Mini-Reviews in Medicinal Chemistry
, vol.6
, Issue.9
, pp. 989-995
-
-
Tamamura, H.1
Tsutsumi, H.2
Fujii, N.3
-
42
-
-
53149130236
-
Thymic emigration: When and how T cells leave home
-
Weinreich MA, Hogquist KA. Thymic emigration: when and how T cells leave home. J Immunol 181: 2265-2270, 2008.
-
(2008)
J Immunol
, vol.181
, pp. 2265-2270
-
-
Weinreich, M.A.1
Hogquist, K.A.2
-
43
-
-
20144388779
-
Discovery of 2,3,5-trisubstituted pyridine derivatives as potent Akt1 and Akt2 dual inhibitors
-
DOI 10.1016/j.bmcl.2004.12.062
-
Zhao Z, Leister WH, Robinson RG, Barnett SF, Defeo-Jones D, Jones RE, Hartman GD, Huff JR, Huber HE, Duggan ME, Lindsley CW. Discovery of 2,3,5-trisubstituted pyridine derivatives as potent Akt1 and Akt2 dual inhibitors. Bioorg Med Chem Lett 15: 905-909, 2005. (Pubitemid 40458621)
-
(2005)
Bioorganic and Medicinal Chemistry Letters
, vol.15
, Issue.4
, pp. 905-909
-
-
Zhao, Z.1
Leister, W.H.2
Robinson, R.G.3
Barnett, S.F.4
Defeo-Jones, D.5
Jones, R.E.6
Hartman, G.D.7
Huff, J.R.8
Huber, H.E.9
Duggan, M.E.10
Lindsley, C.W.11
|