A comparative study of the COX-1 and COX-2 isozymes bound to lipid membranes

Journal of Computational Chemistry

Volumn 30, Issue 7, 2009, Pages 1038-1050

  Wan, Shunzhou ^a   Coveney, Peter V ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Arachidonic acid; Cyclooxygenase; Molecular dynamics simulation; Protein lipid interaction

Indexed keywords

ACTIVE SITE; AQUEOUS ENVIRONMENT; ARACHIDONIC ACID; ARACHIDONIC ACIDS; ATTACHMENT MECHANISM; COMPARATIVE STUDIES; CONFORMATIONAL CHANGE; CYCLOOXYGENASE; HOMODIMER; LIPID BILAYER MEMBRANES; LIPID MEMBRANES; MEMBRANE ASSOCIATION; MOLECULAR DYNAMICS SIMULATION; MOLECULAR DYNAMICS SIMULATIONS; PROTEIN-LIPID INTERACTION;

ACIDS; LIPID BILAYERS; LIPIDS; MEMBRANES; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; PROTEINS;

DYNAMICS;

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; MEMBRANE LIPID; WATER;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; COMPUTER SIMULATION; LIPID BILAYER; METABOLISM; SURFACE PROPERTY;

BINDING SITES; COMPUTER SIMULATION; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; LIPID BILAYERS; MEMBRANE LIPIDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SURFACE PROPERTIES; WATER;

EID: 65949120448     PISSN: 01928651     EISSN: 1096987X     Source Type: Journal    
DOI: 10.1002/jcc.21130     Document Type: Article

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