Hypoglycemia as a predictor of mortality in hospitalized elderly patients

Archives of Internal Medicine

Volumn 163, Issue 15, 2003, Pages 1825-1829

  Kagansky, Nadya ^a,c   Levy, Shmuel ^a   Rimon, Ephraim ^a   Cojocaru, Lutzy ^b   Fridman, Alla ^a   Ozer, Zinaida ^a   Knobler, Hilla ^a  

^a KAPLAN MEDICAL CENTER   (Israel)

^b ASHKELON ACADEMIC COLLEGE   (Israel)

^c Harzfeld Medical Center   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; ELDERLY CARE; FEMALE; HOSPITAL PATIENT; HUMAN; HYPOGLYCEMIA; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MORTALITY; PREDICTION; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR;

AGED; CASE-CONTROL STUDIES; FEMALE; HOSPITAL MORTALITY; HUMANS; HYPOGLYCEMIA; INPATIENTS; ISRAEL; MALE; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE OF TESTS; RISK FACTORS;

EID: 0043156252     PISSN: 00039926     EISSN: None     Source Type: Journal    
DOI: 10.1001/archinte.163.15.1825     Document Type: Article

References (26)

1. The Diabetes Control and Complication Trial Research Group. Hypoglycemia in the Diabetes Control and Complication Trial. Diabetes. 1997;46:271-286.
2. Abraira C, Colwell JA, Nuttall FQ, et al. Veterans Affairs cooperative study on glycemic control and complications in type II diabetes (VS CSDM): results of the feasibility trial. Diabetes Care. 1995;18:1113-1123.
3. UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998; 352:837-853.
4. Miller CD, Phillips LS, Ziemer DC, Gallina DL, Cook CB, El-Kebbi IM. Hypoglycemia in patients with type 2 diabetes mellitus. Arch Intern Med. 2001;161:1653-1659.
5. Fisher KF, Lees JA, Newman JH. Hypoglycemia in hospitalized elderly patients: causes and outcomes. N Engl J Med. 1986;315:1245-1250.
6. Stagnaro-Green A, Barton MK, Linekin PL, Corkery E, deBeer K, Roman SH. Mortality in hospitalized patients with hypoglycemia and severe hyperglycemia. Mt Sinai J Med. 1995;62:422-426.
7. Shilo S, Berezovsky S, Friedlander Y, Sonnenblick M. Hypoglycemia in hospitalized nondiabetic older patients. J Am Geriatr Soc. 1998;46:978-982.
8. Masotti L, Ceccarelli E, Cappelli R, Barabesi L, Guerrini M, Forconi S. Length of hospitalization in elderly patients with community-acquired pneumonia. Aging. 2000;12:35-41.
9. Shorr RI, Ray WA, Daugherty JR, Griffin MR. Incidence and risk factors for serious hypoglycemia in older persons using insulin or sulfonylureas. Arch Intern Med. 1997;157:1681-1686.
10. Meneilly GS, Cheung E, Tuokko H. Altered response to hypoglycemia of healthy elderly people. J Clin Endocrinol Metab. 1994;78:1341-1348.
11. Davis SN, Fowler S, Costa F. Hypoglycemic counterregulatory responses differ between men and women with type 1 diabetes. Diabetes. 2000;49:65-72.
12. Milller SI, Wallace RJ Jr, Musher DM, Septimus EJ, Kohl S, Baughn RE. Hypoglycemia as a manifestation of sepsis. Am J Med. 1980;68:649-659.
13. Filkins JP, Buchanan BJ. In vivo vs in vitro effects of endotoxin on glycogenolysis, gluconeogenesis, and glucose utilization. Proc Soc Exp Biol Med. 1977;155:216-218.
14. Maitra SR, Homan CS, Pan W, Geller ER, Henry MC, Thode HC Jr. Renal gluconeogenesis and blood flow during endotoxic shock. Acad Emerg Med. 1996;3:1006-1010.
15. Klonoff-Cohen H, Barrett-Connor EL, Edelstein SL. Albumin levels as a predictor of mortality in healthy elderly. J Clin Epidemiol. 1992;45:207-212.
16. Phillips A, Shaper AG, Whincup PH. Association between serum albumin and mortality from cardiovascular disease, cancer, and other causes. Lancet. 1989; 2:1434-1436.
17. Fuhrman MP. The albumin-nutrition connection: separating myth from facts. Nutrition. 2002;18:199-200.
18. Steinitz H, Behar M, Alkan WJ. Liver cirrhosis in Israel. Leber Magen Darm. 1978; 8:340-342.
19. Brooks GC, Zimbler AG, Bodenheimer HC Jr, Burchard KW. Patterns of liver test abnormalities in patients with surgical sepsis. Am Surg. 1991;57:656-662.
20. Rutsky EA, McDaniel HG, Tharpe DL, Alred G, Pek S. Spontaneous hypoglycemia in chronic renal failure. Arch Intern Med. 1978;138:1364-1368.
21. Peitzman SJ, Agarwal BN. Spontaneous hypoglycemia in end-stage renal failure. Nephron. 1977;19:131-139.
22. Haviv YS, Sharkia M, Safadi R. Hypoglycemia in patients with renal failure. Ren Fail. 2000;22:219-223.
23. Gerich JE, Meyer C, Woerle HJ, Stumvoll M. Renal gluconeogenesis: its importance in human glucose hemeostasis. Diabetes Care. 2001;24:382-391.
24. Service FJ. Hypoglycemic disorders. N Engl J Med. 1995;332:1144-1152.
25. Hussey HJ, Tisdale MJ. Effect of cachectic factor on carbohydrate metabolism and attenuation by eicasapentaenoic acid. Br J Cancer. 1999;80:1231-1235.
26. Dandona P, Aljada A, Mohanty P. The antiinflammatory and potential antiatherogenic effect of insulin: a new paradigm. Diabetologia. 2002;45:924-930.