Dynamic balance of pSTAT1 and pSTAT3 in C57BL/6 mice infected with lethal or nonlethal Plasmodium yoelii

Cellular and Molecular Immunology

Volumn 5, Issue 5, 2008, Pages 341-348

  Shi, Xibao ^a,b   Qin, Li ^a   Liu, Guangjie ^a   Zhao, Siting ^a   Peng, Nanzheng ^a   Chen, Xiaoping ^a,b  

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

malaria; Plasmodium yoelii; pSTAT1; pSTAT3

Indexed keywords

CYTOKINE; STAT1 PROTEIN; STAT1 PROTEIN, MOUSE; STAT3 PROTEIN; STAT3 PROTEIN, MOUSE;

ANIMAL; ARTICLE; C57BL MOUSE; FEMALE; MALARIA; METABOLISM; MOUSE; PARASITOLOGY; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PLASMODIUM YOELII; SPLEEN;

ANIMALS; CYTOKINES; FEMALE; MALARIA; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PLASMODIUM YOELII; SPLEEN; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR;

EID: 65849528430     PISSN: 16727681     EISSN: None     Source Type: Journal    
DOI: 10.1038/cmi.2008.42     Document Type: Article

References (43)

1. Stevenson MM, Riley EM. Innate immunity to malaria. Nat Rev Immunol. 2004;4:169-180. (Pubitemid 38339083)
2. Stevenson MM, Tam MF, Wolf SF, Sher A. IL-12-induced protection against blood-stage Plasmodium chabaudi as requires IFN-γ and TNF-α and occurs via a nitric oxide-dependent mechanism. J Immunol. 1995;155:2545-2556.
3. Stevenson MM, Urban BC. Antigen presentation and dendritic cell biology in malaria. Parasite Immunol. 2006;28:5-14.
4. Su Z, Stevenson MM. Central role of endogenous γ interferon in protective immunity against blood-stage Plasmodium chabaudi as infection. Infect Immun. 2000;68:4399-4406. (Pubitemid 30497704)
5. Tsutsui N, Kamiyama T. Transforming growth factor β-induced failure of resistance to infection with blood-stage Plasmodium chabaudi in mice. Infect Immun. 1999;67:2306-2311. (Pubitemid 29200486)
6. Torre D, Speranza F, Martegani R. Role of proinflammatory and anti-inflammatory cytokines in the immune response to Plasmodium falciparum malaria. Lancet Infect Dis. 2002;2:719-720. (Pubitemid 35434556)
7. Omer FM, Kurtzhals JA, Riley EM. Maintaining the immunological balance in parasitic infections: a role for TGF-β? Parasitol Today (Personal ed). 2000;16:18-23. (Pubitemid 30101611)
8. Artavanis-Tsakonas K, Tongren JE, Riley EM. The war between the malaria parasite and the immune system: immunity, immunoregulation and immunopathology. Clin Exp Immunol. 2003;133:145-152. (Pubitemid 36918587)
9. Dodoo D, Omer FM, Todd J, Akanmori BD, Koram KA, Riley EM. Absolute levels and ratios of proinflammatory and anti-inflammatory cytokine production in vitro predict clinical immunity to Plasmodium falciparum malaria. J Infect Dis. 2002;185:971-979. (Pubitemid 34274441)
10. Li C, Corraliza I, Langhorne J. A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in mice. Infect Immun. 1999;67:4435-4442. (Pubitemid 29400417)
11. Omer FM, Riley EM. Transforming growth factor β production is inversely correlated with severity of murine malaria infection. J Exp Med. 1998;188:39-48. (Pubitemid 28328604)
12. Omer FM, de Souza JB, Riley EM. Differential induction of TGF-β regulates proinflammatory cytokine production and determines the outcome of lethal and nonlethal Plasmodium yoelii infections. J Immunol. 2003;171:5430-5436. (Pubitemid 37432830)
13. De Souza JB, Williamson KH, Otani T, Playfair JH. Early γ interferon responses in lethal and nonlethal murine blood-stage malaria. Infect Immun. 1997;65:1593-1598. (Pubitemid 27193574)
14. Torre D, Speranza F, Giola M, Matteelli A, Tambini R, Biondi G. Role of Th1 and Th2 cytokines in immune response to uncomplicated Plasmodium falciparum malaria. Clin Diagn Lab Immunol. 2002;9:348-351. (Pubitemid 34226030)
15. Kobayashi F, Ishida H, Matsui T, Tsuji M. Effects of in vivo administration of anti-IL-10 or anti-IFN-γ monoclonal antibody on the host defense mechanism against Plasmodium yoelii yoelii infection. Melatonin regulates nitric oxide synthase expression in ischemic brain injury. J Vet Med Sci. 2000;62:583-587.
16. Chen WG, Daines MO, Hershey GKK. Turning off signal transducer and activator of transcription (STAT): The negative regulation of STAT signaling. J Allergy Clin Immunol. 2004;114:476-489. (Pubitemid 39194916)
17. Ihle JN. STATs: signal transducers and activators of transcription. Cell. 1996;84:331-334. (Pubitemid 26058558)
18. Durbin JE, Hackenmiller R, Simon MC, Levy DE. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell. 1996;84:443-450. (Pubitemid 26058569)
19. Meraz MA, White JM, Sheehan KC, et al. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell. 1996;84:431-442. (Pubitemid 26058568)
20. Rosas LE, Keiser T, Pyles R, Durbin J, Satoskar AR. Development of protective immunity against cutaneous leishmaniasis is dependent on STAT1-mediated IFN signaling pathway. Eur J Immunol. 2003;33:1799-1805. (Pubitemid 37120850)
21. Szabo SJ, Sullivan BM, Peng SL, Glimcher LH. Molecular mechanisms regulating Th1 immune responses. Annu Rev Immunol. 2003;21:713-758. (Pubitemid 37174546)
22. Vakkila J, Demarco RA, Lotze MT. Coordinate NF-κB and STAT1 activation promotes development of myeloid type 1 dendritic cells. Scand J Immunol. 2008;67:260-269. (Pubitemid 351197169)
23. Jackson SH, Yu CR, Mahdi RM, Ebong S, Egwuagu CE. Dendritic cell maturation requires STAT1 and is under feedback regulation by suppressors of cytokine signaling. J Immunol. 2004;172:2307-2315. (Pubitemid 38182378)
24. Carson WE, Dierksheide JE, Jabbour S, et al. Coadministration of interleukin-18 and interleukin-12 induces a fatal inflammatory response in mice: critical role of natural killer cell interferon-γ production and STAT-mediated signal transduction. Blood. 2000;96:1465-1473. (Pubitemid 30658478)
25. + regulatory T cells. Proc Natl Acad Sci U S A. 2007;104:18169-18174. (Pubitemid 350210839)
26. Dunn GP, Koebel CM, Schreiber RD. Interferons, immunity and cancer immunoediting. Nat Rev. 2006;6:836-848. (Pubitemid 44631652)
27. Hong F, Jaruga B, Kim WH, et al. Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS. J Clin Invest. 2002;110:1503-1513. (Pubitemid 35396921)
28. Gabriella R, Sara P, Daniela B, Francesco N, Valeria P. Ups and downs: the STAT1:STAT3 seesaw of interferon and gp130 receptor signalling. Semin Cell Dev Biol. 2008; in press.
29. Yu H, Jove R. The STATs of cancer-new molecular targets come of age. Nat Rev Cancer. 2004;4:97-105. (Pubitemid 38198738)
30. El Kasmi KC, Holst J, Coffre M, et al. General nature of the STAT3-activated anti-inflammatory response. J Immunol. 2006;177:7880-7888. (Pubitemid 44846303)
31. Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol. 2007;7:41-51. (Pubitemid 46020826)
32. Kortylewski M, Kujawski M, Wang T, et al. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nat Med. 2005;11:1314-1321. (Pubitemid 41752912)
33. Takeda K, Clausen BE, Kaisho T, et al. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity. 1999;10:39-49. (Pubitemid 29077382)
34. Adamkova L, Souckova K, Kovarik J. Transcription protein STAT1: biology and relation to cancer. Folia Biol. 2007;53:1-6. (Pubitemid 46344271)
35. Wang W, Edington HD, Rao UN, et al. STAT3 as a biomarker of progression in atypical nevi of patients with melanoma: doseresponse effects of systemic IFNa therapy. J Invest Dermatol. 2008;128:1997-2002. (Pubitemid 352001210)
36. Wang W, Edington HD, Rao UN, et al. Modulation of signal transducers and activators of transcription 1 and 3 signaling in melanoma by high-dose IFNa2b. Clin Cancer Res. 2007;13:1523-1531. (Pubitemid 46450444)
37. Couper KN, Blount DG, Wilson MS, et al. IL-10 from CD4 CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection. PLoS Pathog. 2008;4: e1000004.
38. Chotivanich K, Udomsangpetch R, McGready R, et al. Central role of the spleen in malaria parasite clearance. J Infect Dis. 2002;185:1538-1541. (Pubitemid 34507982)
39. Oster CN, Koontz LC, Wyler DJ. Malaria in asplenic mice: effects of splenectomy, congenital asplenia, and splenic reconstitution on the course of infection. Am J Trop Med Hyg. 1980;29:1138-1142. (Pubitemid 11212939)
40. Engwerda CR, Beattie L, Amante FH. The importance of the spleen in malaria. Trends Parasitol. 2005;21:75-80. (Pubitemid 40138879)
41. Dockrell HM, de Souza JB, Playfair JH. The role of the liver in immunity to blood-stage murine malaria. Immunology. 1980;41:421-430. (Pubitemid 10006990)
42. Playfair JH, de Souza JB. Lymphocyte traffic and lymphocyte destruction in murine malaria. Immunology. 1982;46:125-133. (Pubitemid 12102479)
43. Shear HL, Nussenzweig RS, Bianco C. Immune phagocytosis in murine malaria. J Exp Med. 1979;149:1288-1298. (Pubitemid 9209540)