메뉴 건너뛰기




Volumn 87, Issue 9, 2009, Pages 2138-2144

Mevastatin-induced neurite outgrowth of neuroblastoma cells via activation of EGFR

Author keywords

NGF; Rab5; Rab7; Rap1

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; COMPACTIN; EPIDERMAL GROWTH FACTOR RECEPTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEURON SPECIFIC NUCLEAR PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; RAB PROTEIN; RAB7 PROTEIN; RAP1 PROTEIN;

EID: 65849407988     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22025     Document Type: Article
Times cited : (35)

References (40)
  • 2
    • 0037366067 scopus 로고    scopus 로고
    • Neuroblastoma: Biological insights into a clinical enigma
    • Brodeur GM. 2003. Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer 3:203-216.
    • (2003) Nat Rev Cancer , vol.3 , pp. 203-216
    • Brodeur, G.M.1
  • 3
    • 34547750315 scopus 로고    scopus 로고
    • Endosomal transport of neurotrophins: Roles in signaling and neurodegenerative diseases
    • Bronfman FC, Escudero CA, Weis J, Kruttgen A. 2007. Endosomal transport of neurotrophins: roles in signaling and neurodegenerative diseases. Dev Neurobiol 67:1183-1203.
    • (2007) Dev Neurobiol , vol.67 , pp. 1183-1203
    • Bronfman, F.C.1    Escudero, C.A.2    Weis, J.3    Kruttgen, A.4
  • 5
    • 0037147320 scopus 로고    scopus 로고
    • Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor
    • Chen X, Resh MD. 2002. Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor. J Biol Chem 277:49631-49637.
    • (2002) J Biol Chem , vol.277 , pp. 49631-49637
    • Chen, X.1    Resh, M.D.2
  • 6
    • 33947138135 scopus 로고    scopus 로고
    • Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation
    • Edsjo A, Holmquist L, Pahlman S. 2007. Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation. Semin Cancer Biol 17:248-256.
    • (2007) Semin Cancer Biol , vol.17 , pp. 248-256
    • Edsjo, A.1    Holmquist, L.2    Pahlman, S.3
  • 7
    • 1342329720 scopus 로고    scopus 로고
    • Neurotrophin effects on neuroblastoma cells: Correlation with trk and p75NTR expression and influence of Trk receptor bodies
    • Evangelopoulos ME, Weis J, Kruttgen A. 2004. Neurotrophin effects on neuroblastoma cells: correlation with trk and p75NTR expression and influence of Trk receptor bodies. J Neurooncol 66:101-110.
    • (2004) J Neurooncol , vol.66 , pp. 101-110
    • Evangelopoulos, M.E.1    Weis, J.2    Kruttgen, A.3
  • 8
    • 18844460415 scopus 로고    scopus 로고
    • Signalling pathways leading to neuroblastoma differentiation after serum withdrawal: HDL blocks neuroblastoma differentiation by inhibition of EGFR
    • Evangelopoulos ME, Weis J, Kruttgen A. 2005. Signalling pathways leading to neuroblastoma differentiation after serum withdrawal: HDL blocks neuroblastoma differentiation by inhibition of EGFR. Oncogene 24:3309-3318.
    • (2005) Oncogene , vol.24 , pp. 3309-3318
    • Evangelopoulos, M.E.1    Weis, J.2    Kruttgen, A.3
  • 10
    • 0032516835 scopus 로고    scopus 로고
    • Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK)
    • Furuchi T, Anderson RG. 1998. Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK). J Biol Chem 273:21099-21104.
    • (1998) J Biol Chem , vol.273 , pp. 21099-21104
    • Furuchi, T.1    Anderson, R.G.2
  • 12
    • 33947508765 scopus 로고    scopus 로고
    • Statin-induced Ras activation integrates the phosphatidylinositol 3-kinase signal to Akt and MAPK for bone morphogenetic protein-2 expression in osteoblast differentiation
    • Ghosh-Choudhury N, Mandal CC, Choudhury GG. 2007. Statin-induced Ras activation integrates the phosphatidylinositol 3-kinase signal to Akt and MAPK for bone morphogenetic protein-2 expression in osteoblast differentiation. J Biol Chem 282:4983-4993.
    • (2007) J Biol Chem , vol.282 , pp. 4983-4993
    • Ghosh-Choudhury, N.1    Mandal, C.C.2    Choudhury, G.G.3
  • 13
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein JL, Brown MS. 1990. Regulation of the mevalonate pathway. Nature 343:425-430.
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 14
    • 49549114025 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin
    • Han J, Wang B, Xiao Z, Gao Y, Zhao Y, Zhang J, Chen B, Wang X, Dai J. 2008. Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin. Mol Cell Neurosci 39:118-124.
    • (2008) Mol Cell Neurosci , vol.39 , pp. 118-124
    • Han, J.1    Wang, B.2    Xiao, Z.3    Gao, Y.4    Zhao, Y.5    Zhang, J.6    Chen, B.7    Wang, X.8    Dai, J.9
  • 15
    • 36148999845 scopus 로고    scopus 로고
    • A comparison between the effects of hydrophobic and hydrophilic statins on osteoclast function in vitro and ovariectomy-induced bone loss in vivo
    • Hughes A, Rogers MJ, Idris AI, Crockett JC. 2007. A comparison between the effects of hydrophobic and hydrophilic statins on osteoclast function in vitro and ovariectomy-induced bone loss in vivo. Calcif Tissue Int 81:403-413.
    • (2007) Calcif Tissue Int , vol.81 , pp. 403-413
    • Hughes, A.1    Rogers, M.J.2    Idris, A.I.3    Crockett, J.C.4
  • 17
    • 0026731811 scopus 로고
    • rab GTP-binding proteins with three different carboxyl-terminal cysteine motifs are modified in vivo by 20-carbon isoprenoids
    • Kinsella BT, Maltese WA. 1992. rab GTP-binding proteins with three different carboxyl-terminal cysteine motifs are modified in vivo by 20-carbon isoprenoids. J Biol Chem 267:3940-3945.
    • (1992) J Biol Chem , vol.267 , pp. 3940-3945
    • Kinsella, B.T.1    Maltese, W.A.2
  • 18
    • 33751184564 scopus 로고    scopus 로고
    • The dark side of the NGF family: Neurotrophins in neoplasias
    • Kruttgen A, Schneider I, Weis J. 2006. The dark side of the NGF family: neurotrophins in neoplasias. Brain Pathol 16:304-310.
    • (2006) Brain Pathol , vol.16 , pp. 304-310
    • Kruttgen, A.1    Schneider, I.2    Weis, J.3
  • 19
    • 0036605377 scopus 로고    scopus 로고
    • Mevastatin induces degeneration and decreases viability of cAMP-induced differentiated neuroblastoma cells in culture by inhibiting proteasome activity, and mevalonic acid lactone prevents these effects
    • Kumar B, Andreatta C, Koustas WT, Cole WC, Edwards-Prasad J, Prasad KN. 2002. Mevastatin induces degeneration and decreases viability of cAMP-induced differentiated neuroblastoma cells in culture by inhibiting proteasome activity, and mevalonic acid lactone prevents these effects. J Neurosci Res 68:627-635.
    • (2002) J Neurosci Res , vol.68 , pp. 627-635
    • Kumar, B.1    Andreatta, C.2    Koustas, W.T.3    Cole, W.C.4    Edwards-Prasad, J.5    Prasad, K.N.6
  • 20
    • 54049105353 scopus 로고    scopus 로고
    • Internalization of EGF receptor following lipid rafts disruption in keratinocytes is delayed and dependent on p38 MAPK activation
    • Lambert S, Ameels H, Gniadecki R, Herin M, Poumay Y. 2008. Internalization of EGF receptor following lipid rafts disruption in keratinocytes is delayed and dependent on p38 MAPK activation. J Cell Physiol 217:834-845.
    • (2008) J Cell Physiol , vol.217 , pp. 834-845
    • Lambert, S.1    Ameels, H.2    Gniadecki, R.3    Herin, M.4    Poumay, Y.5
  • 21
    • 0022398820 scopus 로고
    • Differentiation of neuroblastoma cells induced by an inhibitor of mevalonate synthesis: Relation of neurite outgrowth and acetylcholinesterase activity to changes in cell proliferation and blocked isoprenoid synthesis
    • Maltese WA, Sheridan KM. 1985. Differentiation of neuroblastoma cells induced by an inhibitor of mevalonate synthesis: relation of neurite outgrowth and acetylcholinesterase activity to changes in cell proliferation and blocked isoprenoid synthesis. J Cell Physiol 125:540-558.
    • (1985) J Cell Physiol , vol.125 , pp. 540-558
    • Maltese, W.A.1    Sheridan, K.M.2
  • 23
    • 0036083620 scopus 로고    scopus 로고
    • Heterologous desensitization of EGF receptors and PDGF receptors by sequestration in caveolae
    • Matveev SV, Smart EJ. 2002. Heterologous desensitization of EGF receptors and PDGF receptors by sequestration in caveolae. Am J Physiol Cell Physiol 282:C935-C946.
    • (2002) Am J Physiol Cell Physiol , vol.282
    • Matveev, S.V.1    Smart, E.J.2
  • 25
    • 0347480302 scopus 로고    scopus 로고
    • Neural crest development and neuroblastoma: The genetic and biological link
    • Nakagawara A. 2004. Neural crest development and neuroblastoma: the genetic and biological link. Prog Brain Res 146:233-242.
    • (2004) Prog Brain Res , vol.146 , pp. 233-242
    • Nakagawara, A.1
  • 26
    • 0037072273 scopus 로고    scopus 로고
    • Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking
    • Pike LJ, Casey L. 2002. Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking. Biochemistry 41:10315-10322.
    • (2002) Biochemistry , vol.41 , pp. 10315-10322
    • Pike, L.J.1    Casey, L.2
  • 27
    • 0033597907 scopus 로고    scopus 로고
    • Glycosphingolipid-enriched signaling domain in mouse neuroblastoma Neuro2a cells. Mechanism of ganglioside-dependent neuritogenesis
    • Prinetti A, Iwabuchi K, Hakomori S. 1999. Glycosphingolipid-enriched signaling domain in mouse neuroblastoma Neuro2a cells. Mechanism of ganglioside-dependent neuritogenesis. J Biol Chem 274:20916-20924.
    • (1999) J Biol Chem , vol.274 , pp. 20916-20924
    • Prinetti, A.1    Iwabuchi, K.2    Hakomori, S.3
  • 28
    • 0028856675 scopus 로고
    • A mediator role of ceramide in the regulation of neuroblastoma Neuro2a cell differentiation
    • Riboni L, Prinetti A, Bassi R, Caminiti A, Tettamanti G. 1995. A mediator role of ceramide in the regulation of neuroblastoma Neuro2a cell differentiation. J Biol Chem 270:26868-26875.
    • (1995) J Biol Chem , vol.270 , pp. 26868-26875
    • Riboni, L.1    Prinetti, A.2    Bassi, R.3    Caminiti, A.4    Tettamanti, G.5
  • 29
    • 0037087555 scopus 로고    scopus 로고
    • Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae
    • Ringerike T, Blystad FD, Levy FO, Madshus IH, Stang E. 2002. Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae. J Cell Sci 115:1331-1340.
    • (2002) J Cell Sci , vol.115 , pp. 1331-1340
    • Ringerike, T.1    Blystad, F.D.2    Levy, F.O.3    Madshus, I.H.4    Stang, E.5
  • 30
    • 0037166323 scopus 로고    scopus 로고
    • Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding
    • Roepstorff K, Thomsen P, Sandvig K, van Deurs B. 2002. Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding. J Biol Chem 277:18954-18960.
    • (2002) J Biol Chem , vol.277 , pp. 18954-18960
    • Roepstorff, K.1    Thomsen, P.2    Sandvig, K.3    van Deurs, B.4
  • 32
    • 28044444522 scopus 로고    scopus 로고
    • The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA
    • Saxena S, Bucci C, Weis J, Kruttgen A. 2005. The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA. J Neurosci 25:10930-10940.
    • (2005) J Neurosci , vol.25 , pp. 10930-10940
    • Saxena, S.1    Bucci, C.2    Weis, J.3    Kruttgen, A.4
  • 33
    • 1842510494 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis
    • Schulz JG, Bosel J, Stoeckel M, Megow D, Dirnagl U, Endres M. 2004. HMG-CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis. J Neurochem 89:24-32.
    • (2004) J Neurochem , vol.89 , pp. 24-32
    • Schulz, J.G.1    Bosel, J.2    Stoeckel, M.3    Megow, D.4    Dirnagl, U.5    Endres, M.6
  • 34
    • 0029925683 scopus 로고    scopus 로고
    • Intracellular signaling pathways activated by neurotrophic factors
    • Segal RA, Greenberg ME. 1996. Intracellular signaling pathways activated by neurotrophic factors. Annu Rev Neurosci 19:463-489.
    • (1996) Annu Rev Neurosci , vol.19 , pp. 463-489
    • Segal, R.A.1    Greenberg, M.E.2
  • 35
    • 3042759702 scopus 로고    scopus 로고
    • Sigma-1 receptors potentiate epidermal growth factor signaling towards neuritogenesis in PC12 cells: Potential relation to lipid raft reconstitution
    • Takebayashi M, Hayashi T, Su TP. 2004. Sigma-1 receptors potentiate epidermal growth factor signaling towards neuritogenesis in PC12 cells: potential relation to lipid raft reconstitution. Synapse 53:90-103.
    • (2004) Synapse , vol.53 , pp. 90-103
    • Takebayashi, M.1    Hayashi, T.2    Su, T.P.3
  • 36
    • 0028483678 scopus 로고
    • EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor
    • Traverse S, Seedorf K, Paterson H, Marshall CJ, Cohen P, Ullrich A. 1994. EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor. Curr Biol 4:694-701.
    • (1994) Curr Biol , vol.4 , pp. 694-701
    • Traverse, S.1    Seedorf, K.2    Paterson, H.3    Marshall, C.J.4    Cohen, P.5    Ullrich, A.6
  • 37
    • 0025719945 scopus 로고
    • Inhibition of growth factor signaling pathways by lovastatin
    • Vincent TS, Wulfert E, Merler E. 1991. Inhibition of growth factor signaling pathways by lovastatin. Biochem Biophys Res Commun 180:1284-1289.
    • (1991) Biochem Biophys Res Commun , vol.180 , pp. 1284-1289
    • Vincent, T.S.1    Wulfert, E.2    Merler, E.3
  • 38
    • 37349000972 scopus 로고    scopus 로고
    • Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells
    • Wali VB, Sylvester PW. 2007. Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells. Lipids 42:1113-1123.
    • (2007) Lipids , vol.42 , pp. 1113-1123
    • Wali, V.B.1    Sylvester, P.W.2
  • 39
    • 0346435104 scopus 로고    scopus 로고
    • Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects. Studies with cholesterol enantiomers
    • Westover EJ, Covey DF, Brockman HL, Brown RE, Pike LJ. 2003. Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects. Studies with cholesterol enantiomers. J Biol Chem 278:51125-51133.
    • (2003) J Biol Chem , vol.278 , pp. 51125-51133
    • Westover, E.J.1    Covey, D.F.2    Brockman, H.L.3    Brown, R.E.4    Pike, L.J.5
  • 40
    • 39149103724 scopus 로고    scopus 로고
    • Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury
    • Wu H, Lu D, Jiang H, Xiong Y, Qu C, Li B, Mahmood A, Zhou D, Chopp M. 2008. Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury. J Neurotrauma 25:130-139.
    • (2008) J Neurotrauma , vol.25 , pp. 130-139
    • Wu, H.1    Lu, D.2    Jiang, H.3    Xiong, Y.4    Qu, C.5    Li, B.6    Mahmood, A.7    Zhou, D.8    Chopp, M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.