-
1
-
-
52149097331
-
Statins stimulate RGS-regulated ERK 1/2 activation in human calcified and stenotic aortic valves
-
Anger T, El-Chafchak J, Habib A, Stumpf C, Weyand M, Daniel WG, Hombach V, Hoeher M, Garlichs CD. 2008. Statins stimulate RGS-regulated ERK 1/2 activation in human calcified and stenotic aortic valves. Exp Mol Pathol. 85:101-111.
-
(2008)
Exp Mol Pathol
, vol.85
, pp. 101-111
-
-
Anger, T.1
El-Chafchak, J.2
Habib, A.3
Stumpf, C.4
Weyand, M.5
Daniel, W.G.6
Hombach, V.7
Hoeher, M.8
Garlichs, C.D.9
-
2
-
-
0037366067
-
Neuroblastoma: Biological insights into a clinical enigma
-
Brodeur GM. 2003. Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer 3:203-216.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 203-216
-
-
Brodeur, G.M.1
-
3
-
-
34547750315
-
Endosomal transport of neurotrophins: Roles in signaling and neurodegenerative diseases
-
Bronfman FC, Escudero CA, Weis J, Kruttgen A. 2007. Endosomal transport of neurotrophins: roles in signaling and neurodegenerative diseases. Dev Neurobiol 67:1183-1203.
-
(2007)
Dev Neurobiol
, vol.67
, pp. 1183-1203
-
-
Bronfman, F.C.1
Escudero, C.A.2
Weis, J.3
Kruttgen, A.4
-
5
-
-
0037147320
-
Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor
-
Chen X, Resh MD. 2002. Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor. J Biol Chem 277:49631-49637.
-
(2002)
J Biol Chem
, vol.277
, pp. 49631-49637
-
-
Chen, X.1
Resh, M.D.2
-
6
-
-
33947138135
-
Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation
-
Edsjo A, Holmquist L, Pahlman S. 2007. Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation. Semin Cancer Biol 17:248-256.
-
(2007)
Semin Cancer Biol
, vol.17
, pp. 248-256
-
-
Edsjo, A.1
Holmquist, L.2
Pahlman, S.3
-
7
-
-
1342329720
-
Neurotrophin effects on neuroblastoma cells: Correlation with trk and p75NTR expression and influence of Trk receptor bodies
-
Evangelopoulos ME, Weis J, Kruttgen A. 2004. Neurotrophin effects on neuroblastoma cells: correlation with trk and p75NTR expression and influence of Trk receptor bodies. J Neurooncol 66:101-110.
-
(2004)
J Neurooncol
, vol.66
, pp. 101-110
-
-
Evangelopoulos, M.E.1
Weis, J.2
Kruttgen, A.3
-
8
-
-
18844460415
-
Signalling pathways leading to neuroblastoma differentiation after serum withdrawal: HDL blocks neuroblastoma differentiation by inhibition of EGFR
-
Evangelopoulos ME, Weis J, Kruttgen A. 2005. Signalling pathways leading to neuroblastoma differentiation after serum withdrawal: HDL blocks neuroblastoma differentiation by inhibition of EGFR. Oncogene 24:3309-3318.
-
(2005)
Oncogene
, vol.24
, pp. 3309-3318
-
-
Evangelopoulos, M.E.1
Weis, J.2
Kruttgen, A.3
-
10
-
-
0032516835
-
Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK)
-
Furuchi T, Anderson RG. 1998. Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK). J Biol Chem 273:21099-21104.
-
(1998)
J Biol Chem
, vol.273
, pp. 21099-21104
-
-
Furuchi, T.1
Anderson, R.G.2
-
11
-
-
0033566068
-
Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line
-
Ghosh PM, Ghosh-Choudhury N, Moyer ML, Mott GE, Thomas CA, Foster BA, Greenberg NM, Kreisberg JI. 1999. Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line. Oncogene 18:4120-4130.
-
(1999)
Oncogene
, vol.18
, pp. 4120-4130
-
-
Ghosh, P.M.1
Ghosh-Choudhury, N.2
Moyer, M.L.3
Mott, G.E.4
Thomas, C.A.5
Foster, B.A.6
Greenberg, N.M.7
Kreisberg, J.I.8
-
12
-
-
33947508765
-
Statin-induced Ras activation integrates the phosphatidylinositol 3-kinase signal to Akt and MAPK for bone morphogenetic protein-2 expression in osteoblast differentiation
-
Ghosh-Choudhury N, Mandal CC, Choudhury GG. 2007. Statin-induced Ras activation integrates the phosphatidylinositol 3-kinase signal to Akt and MAPK for bone morphogenetic protein-2 expression in osteoblast differentiation. J Biol Chem 282:4983-4993.
-
(2007)
J Biol Chem
, vol.282
, pp. 4983-4993
-
-
Ghosh-Choudhury, N.1
Mandal, C.C.2
Choudhury, G.G.3
-
13
-
-
0025120211
-
Regulation of the mevalonate pathway
-
Goldstein JL, Brown MS. 1990. Regulation of the mevalonate pathway. Nature 343:425-430.
-
(1990)
Nature
, vol.343
, pp. 425-430
-
-
Goldstein, J.L.1
Brown, M.S.2
-
14
-
-
49549114025
-
Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin
-
Han J, Wang B, Xiao Z, Gao Y, Zhao Y, Zhang J, Chen B, Wang X, Dai J. 2008. Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin. Mol Cell Neurosci 39:118-124.
-
(2008)
Mol Cell Neurosci
, vol.39
, pp. 118-124
-
-
Han, J.1
Wang, B.2
Xiao, Z.3
Gao, Y.4
Zhao, Y.5
Zhang, J.6
Chen, B.7
Wang, X.8
Dai, J.9
-
15
-
-
36148999845
-
A comparison between the effects of hydrophobic and hydrophilic statins on osteoclast function in vitro and ovariectomy-induced bone loss in vivo
-
Hughes A, Rogers MJ, Idris AI, Crockett JC. 2007. A comparison between the effects of hydrophobic and hydrophilic statins on osteoclast function in vitro and ovariectomy-induced bone loss in vivo. Calcif Tissue Int 81:403-413.
-
(2007)
Calcif Tissue Int
, vol.81
, pp. 403-413
-
-
Hughes, A.1
Rogers, M.J.2
Idris, A.I.3
Crockett, J.C.4
-
17
-
-
0026731811
-
rab GTP-binding proteins with three different carboxyl-terminal cysteine motifs are modified in vivo by 20-carbon isoprenoids
-
Kinsella BT, Maltese WA. 1992. rab GTP-binding proteins with three different carboxyl-terminal cysteine motifs are modified in vivo by 20-carbon isoprenoids. J Biol Chem 267:3940-3945.
-
(1992)
J Biol Chem
, vol.267
, pp. 3940-3945
-
-
Kinsella, B.T.1
Maltese, W.A.2
-
18
-
-
33751184564
-
The dark side of the NGF family: Neurotrophins in neoplasias
-
Kruttgen A, Schneider I, Weis J. 2006. The dark side of the NGF family: neurotrophins in neoplasias. Brain Pathol 16:304-310.
-
(2006)
Brain Pathol
, vol.16
, pp. 304-310
-
-
Kruttgen, A.1
Schneider, I.2
Weis, J.3
-
19
-
-
0036605377
-
Mevastatin induces degeneration and decreases viability of cAMP-induced differentiated neuroblastoma cells in culture by inhibiting proteasome activity, and mevalonic acid lactone prevents these effects
-
Kumar B, Andreatta C, Koustas WT, Cole WC, Edwards-Prasad J, Prasad KN. 2002. Mevastatin induces degeneration and decreases viability of cAMP-induced differentiated neuroblastoma cells in culture by inhibiting proteasome activity, and mevalonic acid lactone prevents these effects. J Neurosci Res 68:627-635.
-
(2002)
J Neurosci Res
, vol.68
, pp. 627-635
-
-
Kumar, B.1
Andreatta, C.2
Koustas, W.T.3
Cole, W.C.4
Edwards-Prasad, J.5
Prasad, K.N.6
-
20
-
-
54049105353
-
Internalization of EGF receptor following lipid rafts disruption in keratinocytes is delayed and dependent on p38 MAPK activation
-
Lambert S, Ameels H, Gniadecki R, Herin M, Poumay Y. 2008. Internalization of EGF receptor following lipid rafts disruption in keratinocytes is delayed and dependent on p38 MAPK activation. J Cell Physiol 217:834-845.
-
(2008)
J Cell Physiol
, vol.217
, pp. 834-845
-
-
Lambert, S.1
Ameels, H.2
Gniadecki, R.3
Herin, M.4
Poumay, Y.5
-
21
-
-
0022398820
-
Differentiation of neuroblastoma cells induced by an inhibitor of mevalonate synthesis: Relation of neurite outgrowth and acetylcholinesterase activity to changes in cell proliferation and blocked isoprenoid synthesis
-
Maltese WA, Sheridan KM. 1985. Differentiation of neuroblastoma cells induced by an inhibitor of mevalonate synthesis: relation of neurite outgrowth and acetylcholinesterase activity to changes in cell proliferation and blocked isoprenoid synthesis. J Cell Physiol 125:540-558.
-
(1985)
J Cell Physiol
, vol.125
, pp. 540-558
-
-
Maltese, W.A.1
Sheridan, K.M.2
-
22
-
-
48249142346
-
Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro
-
Martin MG, Perga S, Trovo L, Rasola A, Holm P, Rantamaki T, Harkany T, Castren E, Chiara F, Dotti CG. 2008. Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro. Mol Biol Cell 19:2101-2112.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2101-2112
-
-
Martin, M.G.1
Perga, S.2
Trovo, L.3
Rasola, A.4
Holm, P.5
Rantamaki, T.6
Harkany, T.7
Castren, E.8
Chiara, F.9
Dotti, C.G.10
-
23
-
-
0036083620
-
Heterologous desensitization of EGF receptors and PDGF receptors by sequestration in caveolae
-
Matveev SV, Smart EJ. 2002. Heterologous desensitization of EGF receptors and PDGF receptors by sequestration in caveolae. Am J Physiol Cell Physiol 282:C935-C946.
-
(2002)
Am J Physiol Cell Physiol
, vol.282
-
-
Matveev, S.V.1
Smart, E.J.2
-
24
-
-
36248953746
-
Tracking TrkA's trafficking: NGF receptor trafficking controls NGF receptor signaling
-
Moises T, Dreier A, Flohr S, Esser M, Brauers E, Reiss K, Merken D, Weis J, Kruttgen A. 2007. Tracking TrkA's trafficking: NGF receptor trafficking controls NGF receptor signaling. Mol Neurobiol 35:151-159.
-
(2007)
Mol Neurobiol
, vol.35
, pp. 151-159
-
-
Moises, T.1
Dreier, A.2
Flohr, S.3
Esser, M.4
Brauers, E.5
Reiss, K.6
Merken, D.7
Weis, J.8
Kruttgen, A.9
-
25
-
-
0347480302
-
Neural crest development and neuroblastoma: The genetic and biological link
-
Nakagawara A. 2004. Neural crest development and neuroblastoma: the genetic and biological link. Prog Brain Res 146:233-242.
-
(2004)
Prog Brain Res
, vol.146
, pp. 233-242
-
-
Nakagawara, A.1
-
26
-
-
0037072273
-
Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking
-
Pike LJ, Casey L. 2002. Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking. Biochemistry 41:10315-10322.
-
(2002)
Biochemistry
, vol.41
, pp. 10315-10322
-
-
Pike, L.J.1
Casey, L.2
-
27
-
-
0033597907
-
Glycosphingolipid-enriched signaling domain in mouse neuroblastoma Neuro2a cells. Mechanism of ganglioside-dependent neuritogenesis
-
Prinetti A, Iwabuchi K, Hakomori S. 1999. Glycosphingolipid-enriched signaling domain in mouse neuroblastoma Neuro2a cells. Mechanism of ganglioside-dependent neuritogenesis. J Biol Chem 274:20916-20924.
-
(1999)
J Biol Chem
, vol.274
, pp. 20916-20924
-
-
Prinetti, A.1
Iwabuchi, K.2
Hakomori, S.3
-
28
-
-
0028856675
-
A mediator role of ceramide in the regulation of neuroblastoma Neuro2a cell differentiation
-
Riboni L, Prinetti A, Bassi R, Caminiti A, Tettamanti G. 1995. A mediator role of ceramide in the regulation of neuroblastoma Neuro2a cell differentiation. J Biol Chem 270:26868-26875.
-
(1995)
J Biol Chem
, vol.270
, pp. 26868-26875
-
-
Riboni, L.1
Prinetti, A.2
Bassi, R.3
Caminiti, A.4
Tettamanti, G.5
-
29
-
-
0037087555
-
Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae
-
Ringerike T, Blystad FD, Levy FO, Madshus IH, Stang E. 2002. Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae. J Cell Sci 115:1331-1340.
-
(2002)
J Cell Sci
, vol.115
, pp. 1331-1340
-
-
Ringerike, T.1
Blystad, F.D.2
Levy, F.O.3
Madshus, I.H.4
Stang, E.5
-
30
-
-
0037166323
-
Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding
-
Roepstorff K, Thomsen P, Sandvig K, van Deurs B. 2002. Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding. J Biol Chem 277:18954-18960.
-
(2002)
J Biol Chem
, vol.277
, pp. 18954-18960
-
-
Roepstorff, K.1
Thomsen, P.2
Sandvig, K.3
van Deurs, B.4
-
31
-
-
40849114654
-
Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells
-
Saito A, Saito N, Mol W, Furukawa H, Tsutsumida A, Oyama A, Sekido M, Sasaki S, Yamamoto Y. 2008. Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells. Melanoma Res 18:85-94.
-
(2008)
Melanoma Res
, vol.18
, pp. 85-94
-
-
Saito, A.1
Saito, N.2
Mol, W.3
Furukawa, H.4
Tsutsumida, A.5
Oyama, A.6
Sekido, M.7
Sasaki, S.8
Yamamoto, Y.9
-
32
-
-
28044444522
-
The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA
-
Saxena S, Bucci C, Weis J, Kruttgen A. 2005. The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA. J Neurosci 25:10930-10940.
-
(2005)
J Neurosci
, vol.25
, pp. 10930-10940
-
-
Saxena, S.1
Bucci, C.2
Weis, J.3
Kruttgen, A.4
-
33
-
-
1842510494
-
HMG-CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis
-
Schulz JG, Bosel J, Stoeckel M, Megow D, Dirnagl U, Endres M. 2004. HMG-CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis. J Neurochem 89:24-32.
-
(2004)
J Neurochem
, vol.89
, pp. 24-32
-
-
Schulz, J.G.1
Bosel, J.2
Stoeckel, M.3
Megow, D.4
Dirnagl, U.5
Endres, M.6
-
34
-
-
0029925683
-
Intracellular signaling pathways activated by neurotrophic factors
-
Segal RA, Greenberg ME. 1996. Intracellular signaling pathways activated by neurotrophic factors. Annu Rev Neurosci 19:463-489.
-
(1996)
Annu Rev Neurosci
, vol.19
, pp. 463-489
-
-
Segal, R.A.1
Greenberg, M.E.2
-
35
-
-
3042759702
-
Sigma-1 receptors potentiate epidermal growth factor signaling towards neuritogenesis in PC12 cells: Potential relation to lipid raft reconstitution
-
Takebayashi M, Hayashi T, Su TP. 2004. Sigma-1 receptors potentiate epidermal growth factor signaling towards neuritogenesis in PC12 cells: potential relation to lipid raft reconstitution. Synapse 53:90-103.
-
(2004)
Synapse
, vol.53
, pp. 90-103
-
-
Takebayashi, M.1
Hayashi, T.2
Su, T.P.3
-
36
-
-
0028483678
-
EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor
-
Traverse S, Seedorf K, Paterson H, Marshall CJ, Cohen P, Ullrich A. 1994. EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor. Curr Biol 4:694-701.
-
(1994)
Curr Biol
, vol.4
, pp. 694-701
-
-
Traverse, S.1
Seedorf, K.2
Paterson, H.3
Marshall, C.J.4
Cohen, P.5
Ullrich, A.6
-
38
-
-
37349000972
-
Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells
-
Wali VB, Sylvester PW. 2007. Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells. Lipids 42:1113-1123.
-
(2007)
Lipids
, vol.42
, pp. 1113-1123
-
-
Wali, V.B.1
Sylvester, P.W.2
-
39
-
-
0346435104
-
Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects. Studies with cholesterol enantiomers
-
Westover EJ, Covey DF, Brockman HL, Brown RE, Pike LJ. 2003. Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects. Studies with cholesterol enantiomers. J Biol Chem 278:51125-51133.
-
(2003)
J Biol Chem
, vol.278
, pp. 51125-51133
-
-
Westover, E.J.1
Covey, D.F.2
Brockman, H.L.3
Brown, R.E.4
Pike, L.J.5
-
40
-
-
39149103724
-
Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury
-
Wu H, Lu D, Jiang H, Xiong Y, Qu C, Li B, Mahmood A, Zhou D, Chopp M. 2008. Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury. J Neurotrauma 25:130-139.
-
(2008)
J Neurotrauma
, vol.25
, pp. 130-139
-
-
Wu, H.1
Lu, D.2
Jiang, H.3
Xiong, Y.4
Qu, C.5
Li, B.6
Mahmood, A.7
Zhou, D.8
Chopp, M.9
|