Chapter 5 Multiple Approaches to the Study of Chemokine Receptor Homo- and Heterodimerization

Methods in Enzymology

Volumn 461, Issue B, 2009, Pages 105-122

  Rodríguez Frade, JoséMiguel ^a   Muñoz, Laura Martinez ^a   Mellado, Mario ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; FLUORESCENT DYE; HETERODIMER; HOMODIMER;

ANTIBODY LABELING; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; DIMERIZATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; IMMUNOPRECIPITATION; MOLECULAR DYNAMICS; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN LOCALIZATION; REVIEW; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL LINE; FLUORESCENCE RESONANCE ENERGY TRANSFER; IMMUNOPRECIPITATION; MICE; MODELS, BIOLOGICAL; PROTEIN BINDING; PROTEIN MULTIMERIZATION; RECEPTORS, CHEMOKINE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 65749108703     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(09)05405-6     Document Type: Review

References (43)

1. Alcami A. Viral mimicry of cytokines, chemokines and their receptors. Nat. Rev. Immunol. 3 (2003) 36-50
2. Angers S., Salahpour A., and Bouvier M. Dimerization: An emerging concept for G protein-coupled receptor ontogeny and function. Ann. Rev. Pharmacol. Toxicol. 42 (2002) 409-443
3. Audet N., Galés C., Archer-Lahlou E., Vallières M., Schiller P.W., Bouvier M., and Pineyro G. Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing d-opioid receptors and heterotrimeric G proteins. J. Biol. Chem. 283 (2008) 15078-15088
4. Baggiolini M. Chemokines and leukocyte traffic. Nature 392 (1998) 565-568
5. Belperio J.A., Keane M.P., Arenberg D.A., Addison C.L., Ehlert J.E., Burdick M.D., and Trieter R.M. CXC chemokines in angiogenesis. J. Leuk. Biol. 68 (2000) 1-8
6. Berger E.A., Murphy P.M., and Farber J.M. Chemokines as HIV-1 coreceptors: Roles in viral entry, tropism and disease. Annu. Rev. Immunol. 17 (1999) 657-700
7. Borroni E.M., Bonecchi R., Buracchi C., Savino B., Mantovani A., and Locati M. Chemokine decoy receptors: New players in reproductive immunology. Immunol. Invest. 37 (2008) 483-497
8. Boute N., Jockers R., and Issad T. The use of resonance energy transfer in high-throughput screening: BRET versus FRET. Trends Pharmacol. Sci. 23 (2002) 351-354
9. Cardullo R.A. Theoretical principles and practical considerations for fluorescence resonance energy transfer microscopy. Met. Cell. Biol. 81 (2007) 479-494
10. Carriba P., Navarro G., Ciruela F., Ferré S., Casado V., Agnati L., Cortés A., Mallo J., Fuxe K., Canela E.I., Lluis C., and Franco R. Detection of heteromerization of more than two proteins by sequential BRET-FRET. Nat. Methods 5 (2008) 727-733
11. Coulon V., Audet M., Homburger V., Bockaert J., Fagni L., Bouvier M., and Perroy J. Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer. Biophys. J. 94 (2008) 1001-1009
12. Harrison C., and van der Graaf P.H. Current methods used to investigate G protein coupled receptor oligomerisation. J. Pharmacol. Toxicol. Methods 54 (2006) 26-35
13. Hernanz-Falcon P., Rodriguez-Frade J.M., Serrano A., Juan D., del Sol A., Soriano S.F., Roncal F., Gomez L., Valencia A., Martinez-A C., and Mellado M. Identification of amino acid residues crucial for chemokine receptor dimerization. Nat. Immunol. 5 (2004) 216-223
14. Horuk R. Chemokine receptors. Cytokine Growth Factor Rev. 12 (2001) 313-335
15. Kenworthy A.K. Imaging protein-protein interactions using fluorescence resonance energy transfer microscopy. Methods 24 (2001) 289-296
16. Loetscher P., Seitz M., Baggiolini M., and Moser B. Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. J. Exp. Med. 184 (1996) 569-577
17. Mackay C.R. Chemokines: Immunology's high impact factors. Nat. Immunol. 2 (2001) 95-101
18. McVey M., Ramsay D., Kellet E., Rees S., Wilson S., Pope A.J., and Milligan G. Monitoring receptor oligomerization using time-resolved fluorescence resonance energy transfer and bioluminescence resonance energy transfer. J. Biol. Chem. 276 (2001) 14092-14099
19. Mellado M., Rodríguez-Frade J.M., Mañes S., and Martínez-A C. Chemokine signaling and functional responses: The role of receptor dimerization and TK pathway activation. Ann. Rev. Immunol. 19 (2001) 397-421
20. Mellado M., Rodriguez-Frade J.M., Vila-Coro A.J., Fernandez S., Martin de Ana A., Jones D.R., Toran J.L., and Martínez A.C. Chemokine receptor homo- or heterodimerization activates distinct signaling pathways. EMBO J. 20 (2001) 2497-2507
21. Müller A., Homey B., Soto H., Ge N., Catron D., Buchanan M., McClanahan T., Murphy E., Yuan W., Wagner S.N., Barrera J.L., Mohar A., et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 410 (2001) 50-56
22. Papadopoulus E.J., Sassetti C., Saeki H., Yamada N., Kawamura T., Fitzhugh D.J., Saraf M.A., Schall T.J., Blauvelt A., Rosen S.D., and Hwang S.T. Fractalkine, a CXCR3 chemokine is expressed by dendritic cells and is up-regulated upon dendritic cell maturation. Eur. J. Immunol. 29 (1999) 2551-2559
23. Parks E., Strieter R.M., Lukacs N.W., Gauldie J., Hitt M., Graham F.L., and Kunkel S.L. Transient gene transfer of IL-2 regulates chemokine expression and disease severity in experimental arthritis. J. Immunol. 160 (1998) 4615-4619
24. Pello O.M., Martínez-Muñoz L., Parrillas V., Serrano A., Rodríguez-Frade J.M., Toro M.J., Lucas P., Monterrubio M., Martinez A.C., and Mellado M. Ligand stabilization of CXCR4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation. Eur. J. Immunol. 38 (2008) 537-549
25. Percherancier Y., Berchiche Y.A., Slight I., Volkmer-Engert R., Tamamura H., Fujii N., Bouvier M., and Heveker N. Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo- and heterodimers. J. Biol. Chem. 280 (2005) 9895-9903
26. Periasami A., Elangovan M., Elliot E., and Brautigan D.L. Fluorescence lifetime imaging (FLIM) of green fluorescent fusion proteins in living cells. Met. Mol. Biol. 183 (2002) 189-200
27. Pfleger K.D., and Eidne K.A. Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET). Nat. Methods 3 (2006) 165-174
28. Pfleger K.D., Seeber R.M., and Eidne K.A. Bioluminescence resonance energy transfer (BRET) for the real-time detection of protein-protein interactions. Nat. Protoc. 1 (2006) 337-345
29. Pollok B.A., and Heim R. Using GFP in FRET-based applications. Trends Cell. Biol. 9 (1999) 57-60
30. Proudfoot A.E.I. Chemokine receptors: Multifaceted therapeutic targets. Nat. Rev. Immunol. 2 (2002) 106-115
31. Raz E. Primordial germ-cell development: The zebrafish perspective. Nat. Rev. Genet. 4 (2003) 690-700
32. Rodriguez-Frade J.M., Vila-Coro A.J., de Ana A.M., Albar J.P., Martinez-A C., and Mellado M. The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2. Proc. Natl. Acad. Sci. USA 96 (1999) 3628-3633
33. Rossi D., and Zlotnik A. The biology of chemokines and their receptors. Annu. Rev. Immunol. 18 (2000) 217-242
34. Sallusto F., Lanzavecchia A., and Mackay C. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol. Today 19 (1998) 568-574
35. Soriano S.F., Serrano A., Hernanz-Falcón P., Martín de Ana A., Monterrubio M., Martínez-A C., Rodríguez-Frade J.M., and Mellado M. Chemokines integrate JAK/STAT and G-protein pathways during chemotaxis and calcium flux responses. Eur. J. Immunol. 33 (2003) 1328-1333
36. Thelen M., and Baggiolini M. Is dimerization of chemokine receptors functionally relevant?. Sci. STKE. 104 (2001) PE34
37. Thelen M., and Stein J.V. How chemokines invite leukocytes to dance. Nat. Immunol. 9 (2008) 953-959
38. Tian Y., New D.C., Yung L.Y., Allen R.A., Slocombe P.M., Twomey B.M., Lee M.M., and Wong Y.H. Differential chemokine activation of CC chemokine receptor 1-regulated pathways: Ligand selective activation of Galpha 14-coupled pathways. Eur. J. Immunol. 34 (2004) 785-795
39. Vila-Coro A.J., Mellado M., Martin de Ana A., Lucas P., del Real G., Martinez-A C., and Rodriguez-Frade J.M. HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization. Proc. Natl. Acad. Sci. USA 97 (2000) 3388-3393
40. Sekar R.B., and Periasami A. Fluorescence resonance energy transfer (FRET) microscopy imaging of live cell protein localizations. J. Cell. Biol. 160 (2003) 629 623
41. Wang J., He L., Combs C.A., Roderiquez G., and Norcross M.A. Dimerization of CXCR4 in living malignant cells: Control of cell migration by a synthetic peptide that reduces homologous CXCR4 interactions. Mol. Cancer Ther. 5 (2006) 2474-2483
42. Wilson S., Wilkinson G., and Milligan G. The CXCR1 and CXCR2 receptors form constitutive homo- and heterodimers selectively and with equal apparent affinities. J. Biol. Chem. 280 (2005) 28663-28674
43. Zimmermann T., Rietdorf J., Girod A., Georget V., and Pepperkok R. Spectral imaging and linear un-mixing enables improved FRET efficiency with a novel GFP2-YFP FRET pair. FEBS Letters 531 (2002) 245-249