Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation

European Journal of Immunology

Volumn 29, Issue 8, 1999, Pages 2551-2559

  Papadopoulos, Elektra J ^a   Sassetti, Chris ^b   Saeki, Hidehisa ^a   Yamada, Nobuo ^a   Kawamura, Tatsuyoshi ^a   Fitzhugh, David J ^a   Saraf, Manisha A ^a   Schall, Thomas ^c   Blauvelt, Andrew ^a   Rosen, Steven D ^b   Hwang, Sam T ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Building 10 ^*

Author keywords

Chemokine; Dendritic cell; Skin

Indexed keywords

ALPHA CHEMOKINE; B7 ANTIGEN; CD1 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL COMMUNICATION; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; EPIDERMIS; FEMALE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; LANGERHANS CELL; LYMPHOID ORGAN; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; BASE SEQUENCE; CD40 LIGAND; CELL ADHESION; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL LINE; CHEMOKINES, CX3C; CHEMOKINES, CXC; DENDRITIC CELLS; DNA PRIMERS; HUMANS; LANGERHANS CELLS; MELANOCYTES; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; RNA, MESSENGER; SKIN; T-LYMPHOCYTES; TONSIL; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0032794757     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199908)29:08<2551::AID-IMMU2551>3.0.CO;2-T     Document Type: Article

References (36)

1. Baggiolini, M., Chemokines and leukocyte traffic. Nature 1998. 392: 565-568.
2. Bazan, J. F., Bacon, K. B., Hardiman, G., Wang, W., Soo, K., Rossi, D., Greaves, D. R., Zlotnik, A. and Schall, T. J., A new class of membrane-bound chemokine with a CX3C motif. Nature 1997. 385: 640-644.
3. Pan, Y., Lloyd, C., Zhou, H., Dolich, S., Deeds, J., Gonzalo, J.-A., Vath, J., Gosselin, M., Ma, J., Dussault, B., Woolf, E., Alperin, G., Culpepper, J., Guttierrez-Ramos, J. C. and Gearing, D., Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation. Nature 1997. 387: 611-617.
4. Imai, T., Hieshima, K., Haskell, C., Baba, M., Nagira, M., Nishimura, M., Kakizaki, M., Takagi, S., Nomiyama, H., Schall, T. J. and Yoshie, O., Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell 1997. 91: 521-530.
5. Fong, A. M., Robinson, L. A., Steeber, O. A., Tedder, T. F., Yoshie, O., Imai, T. and Patel, D. D., Fractalkine and CX3CR1 mediate a novel mechanisms of leukocyte capture, firm adhesion, and activation under physiologic flow. J. Exp. Med. 1998. 188: 1413-1419.
6. Combadiere, C., Salzwedel, K., Smith, E. D., Tiffany, H. L., Berger, E. A. and Murphy, P. M., Identification of CX3CR1: a chemotactic receptor for the human CX3C chemokine fractalkine and a fusion coreceptor for HIV-1. J. Biol. Chem. 1998. 273: 23799-23804.
7. Harrison, J. K., Jiang, Y., Chen, S., Xia, Y., Maciejewski, D., McNamara, R. K., Streit, W. J., Salafranca, M. N., Adhikari, S., Thompson, D. A., Botti, P., Bacon, K. B. and Feng, L., Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia. Proc. Natl. Acad. Sci. USA 1998. 95: 10896-10901.
8. Chen, S., Bacon, K. B., Li, L., Garcia, G. E., Xia, Y., Lo, D., Thompson, D. A., Siani, M. A., Yamamoto, T., Harrison, J. K. and Feng, L., In vivo inhibition of CC and CX3C chemokine-induced leukocyte infiltration and attenuation of glomerulonephritis in Wistar-Kyoto (WKY) rats by vMIP-II. J. Exp. Med. 1998. 188: 193-198.
9. Larsen, C. P. and Austyn, J. M., Langerhans cells migrate out of skin grafts and cultured skin: a model in which to study the mediators of dendritic leukocyte migration. Transplant. Proc. 1991. 23: 117-119.
10. Xu, S., Bergstresser, P. R. and Takashima, A., Phenotypic and functional heterogeneity among murine epidermal-derived dendritic cells clones. J. Immunol. 1995. 105: 831-836.
11. Caux, C., Massacrier, C., Vanbervliet, B., Dubois, B., Van Kooten, C., Durand, I. and Banchereau, J., Activation of human dendritic cells through CD40 cross-linking. J. Exp. Med. 1994. 1994: 1263-1272.
12. Sallusto, F., Schaerli, P., Loetscher, P., Schaniel, C., Lenig, D., Mackay, C. R., Qin, S. and Lanzavecchia, A., Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Eur. J. Immunol. 1998. 28: 2760-2769.
13. Ngo, V. N., Tang, H. L. and Cyster, J. G., Epstein-Barr Virus-induced molecule 1 ligand chemokine is expressed by dendritic cells in lymphoid tissues and strongly attracts naive T cells and activated B cells. J. Exp. Med. 1998. 188: 181-191.
14. Sozzani, S., Luini, W., Borsatti, A., Polentarutti, N., Zhou, D., Piemonti, L., D'Amico, G., Power, C. A., Wells, T. N., Gobbi, M., Allavena, P. and Mantovani, A., Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines. J. Immunol. 1997. 159: 1993-2000.
15. Bhawan, J., Mel-5: a novel antibody for differential diagnosis of epidermal pigmented lesions of the skin in paraffin-embedded sections. Melanoma Res. 1997. 7: 43-48.
16. Orlow, S. J., Congenital and genetic disorders associated with hypopigmentation. Curr. Prob. Dermatol. 1994. 6: 157-184.
17. + T cells. J. Exp. Med. 1997. 185: 2133-2141.
18. Zhou, L. J. and Tedder, T. F., Human bood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. J. Immunol. 1995. 154: 3821-3835.
19. Romani, N., Reider, D., Heuer, M., Ebner, S., Kampgen, E., Eibl, B., Niederwieser, D. and Schuler, G., Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability. J. Immunol. Methods 1996. 196: 137-151.
20. Sallusto, F. and Lanzavecchia, A., Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 1994. 179: 1109-1118.
21. Cumberbatch, M., Fielding, I. and Kimber, I., Modulation of epidermal Langerhans' cell frequency by tumour necrosis factor-alpha. Immunology 1994. 81: 395-401.
22. Saeki, H., Moore, A. M., Brown, M. J. and Hwang, S. T., Secondary lymphoid-tissue chemokine (SLC) and CCR7 participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes. J. Immunol. 1999. 162: 2472-2475.
23. Lenz, A., Heine, M., Schuler, G. and Romani, N., Human and murine dermis contain dendritic cells: isolation by means of a novel method and phenotypical and functional characterization. J. Clin. Invest. 1993. 92: 2587-2596.
24. Cella, M., Scheidegger, D., Palmer-Lehman, K., Lane, P., Lanzavecchia, A. and Alber, G., Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J. Immunol. 1996. 184: 747-752.
25. Buelens, C., Verhasselt, V., De Groote, D., Thielemans, K., Goldman, M. and Willems, F., Human dendritic cell responses to lipopolysaccharide and CD40 ligation are differentially regulated by interleukin-10. Eur. J. Immunol. 1997. 27: 1848-1852.
26. Péguet-Navarro, J., Dalbiez-Gauthier, C., Rattis, F.-M., Van Cooten, C., Banchereau, J. and Schmitt, D., Functional expression of DC40 antigen on human epidermal Langerhans cells. J. Immunol. 1995. 155: 4241-4247.
27. Gottlieb, A. B., Luster, A. D., Posnett, D. N. and Carter, D. M., Detection of a gamma interferon-induced protein IP-10 in psoriatic plaques. J. Exp. Med. 1998. 168: 941-948.
28. Koedam, J. A., Cramer, E. M., Briend, E., Furie, B., Furie, B. C. and Wagner, D. D., P-selectin, a granule membrane protein of platelets and endothelial cells, follows the regulated secretory pathway in AtT-20 cells. J. Cell Biol. 1992. 116: 617-625.
29. Walcheck, B., Kahn, J., Fisher, J. M., Wang, B. B., Fisk, R. S., Payan, D. G., Feehan, C., Betageri, R., Barlak, K., Spatola, A. F. and Kishimoto, T. K., Neutrophil rolling altered by inhibition of L-selectin shedding in vitro. Nature 1996. 380: 720-723.
30. + T-helper and a T-killer cell. Nature 1998. 393: 474-478.
31. Mackey, M. F., Gunn, J. R., Maliszewski, C., Kikutani, H., Noelle, R. J. and Barth, R. J., Dendritic cells require maturation via CD40 to generate protective antitumor immunity. J. Immunol. 1998. 161: 2094-2098.
32. Zaitseva, M., Blauvelt, A., Lee, S., Lapham, C. K., Klaus-Kovtun, V., Mostowski, H., Manischewitz, J. and Golding, H., Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: implications for HIV primary infection. Nat. Med. 1997. 3: 1369-1375.
33. Blauvelt, A., Asada, H., Saville, M. W., Klaus-Kovtun, V., Altman, D. J., Yarchoan, R. and Katz, S. I., Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways. J. Clin. Invest. 1997. 100: 2043-2053.
34. Geissmann, F., Prost, G., Monnet, J.-P., Dy, M., Brousse, N. and Hermine, O., Transforming Growth Factor β1, in the presence of Granulocyte/Macrophage Colony-stimulating Factor and Interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cells. J. Exp. Med. 1998. 187: 961-966.
35. Larsen, C. P., Steinman, R. M., Witmer-Pack, M., Hankins, D. F., Morris, P. J. and Austyn, J. M., Migration and maturation of Langerhans cells in skin transplants and explants. J. Exp. Med. 1990. 172: 1483-1493.
36. Tamaki, K., Fujiwara, H. and Katz, S. I., The role of epidermal cells in the induction and suppression of contact sensitivity. J. Invest. Dermatol. 1981. 76: 275-278.