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Volumn 11, Issue 1, 2009, Pages 59-65

Monitoring antimalarial drug efficacy: Current challenges

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISININ;

EID: 65649145325     PISSN: 15233847     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11908-009-0009-3     Document Type: Review
Times cited : (18)

References (45)
  • 2
    • 7244219957 scopus 로고    scopus 로고
    • In vivo assessment of drug efficacy against Plasmodium falciparum malaria: Duration of follow-up
    • Stepniewska K, Taylor WR, Mayxay M, et al.: In vivo assessment of drug efficacy against Plasmodium falciparum malaria: Duration of follow-up. Antimicrob Agents Chemother 2004, 48:4271-4280.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 4271-4280
    • Stepniewska, K.1    Taylor, W.R.2    Mayxay, M.3
  • 4
    • 0021345247 scopus 로고
    • Absence of malaria mortality in villagers with chloroquine-resistant Plasmodium falciparum treated with chloroquine
    • Hoffman SL, Masbar S, Hussein PR, et al.: Absence of malaria mortality in villagers with chloroquine-resistant Plasmodium falciparum treated with chloroquine. Trans R Soc Trop Med Hyg 1984, 78:175-178.
    • (1984) Trans R Soc Trop Med Hyg , vol.78 , pp. 175-178
    • Hoffman, S.L.1    Masbar, S.2    Hussein, P.R.3
  • 5
    • 10744233894 scopus 로고    scopus 로고
    • Clearance of drug-resistant parasites as a model for protective immunity in Plasmodium falciparum malaria
    • Djimde AA, Doumbo OK, Traore O, et al.: Clearance of drug-resistant parasites as a model for protective immunity in Plasmodium falciparum malaria. Am J Trop Med Hyg 2003, 69:558-563.
    • (2003) Am J Trop Med Hyg , vol.69 , pp. 558-563
    • Djimde, A.A.1    Doumbo, O.K.2    Traore, O.3
  • 6
    • 38449087184 scopus 로고    scopus 로고
    • Malaria treatment efficacy among people living with HIV: The role of host and parasite factors
    • Laufer MK, van Oosterhout JJ, Thesing PC, et al.: Malaria treatment efficacy among people living with HIV: The role of host and parasite factors. Am J Trop Med Hyg 2007, 77:627-632.
    • (2007) Am J Trop Med Hyg , vol.77 , pp. 627-632
    • Laufer, M.K.1    van Oosterhout, J.J.2    Thesing, P.C.3
  • 7
    • 61849119515 scopus 로고    scopus 로고
    • Decreasing efficacy of antimalarial combination therapy in Uganda explained by decreasing host immunity rather than increasing drug resistance
    • in press
    • Greenhouse B, Slater M, Njama-Meya D, et al.: Decreasing efficacy of antimalarial combination therapy in Uganda explained by decreasing host immunity rather than increasing drug resistance. J Infect Dis, in press.
    • J Infect Dis
    • Greenhouse, B.1    Slater, M.2    Njama-Meya, D.3
  • 8
    • 18244404066 scopus 로고    scopus 로고
    • Blood folate concentrations and in vivo sulfadoxine-pyrimethamine failure in Malawian children with uncomplicated Plasmodium falciparum malaria
    • Dzinjalamala FK, MacHeso A, Kublin JG, et al.: Blood folate concentrations and in vivo sulfadoxine-pyrimethamine failure in Malawian children with uncomplicated Plasmodium falciparum malaria. Am J Trop Med Hyg 2005, 72:267-272.
    • (2005) Am J Trop Med Hyg , vol.72 , pp. 267-272
    • Dzinjalamala, F.K.1    MacHeso, A.2    Kublin, J.G.3
  • 9
    • 33846985615 scopus 로고    scopus 로고
    • The interaction between HIV and malaria in Africa
    • Laufer MK, Plowe CV: The interaction between HIV and malaria in Africa. Curr Infect Dis Rep 2007, 9:47-54.
    • (2007) Curr Infect Dis Rep , vol.9 , pp. 47-54
    • Laufer, M.K.1    Plowe, C.V.2
  • 10
    • 33644899921 scopus 로고    scopus 로고
    • Impact of HIV-associated immunosuppression on malaria infection and disease in Malawi
    • Laufer MK, van Oosterhout JJ, Thesing PC, et al.: Impact of HIV-associated immunosuppression on malaria infection and disease in Malawi. J Infect Dis 2006, 193:872-878.
    • (2006) J Infect Dis , vol.193 , pp. 872-878
    • Laufer, M.K.1    van Oosterhout, J.J.2    Thesing, P.C.3
  • 11
    • 33646736568 scopus 로고    scopus 로고
    • Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria
    • Price RN, Uhlemann AC, van Vugt M, et al.: Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria. Clin Infect Dis 2006, 42:1570-1577.
    • (2006) Clin Infect Dis , vol.42 , pp. 1570-1577
    • Price, R.N.1    Uhlemann, A.C.2    van Vugt, M.3
  • 12
    • 0032862673 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics and pharmacodynamics of artemetherlumefantrine
    • White NJ, van Vugt M, Ezzet F: Clinical pharmacokinetics and pharmacodynamics and pharmacodynamics of artemetherlumefantrine. Clin Pharmacokinet 1999, 37:105-125.
    • (1999) Clin Pharmacokinet , vol.37 , pp. 105-125
    • White, N.J.1    van Vugt, M.2    Ezzet, F.3
  • 13
    • 41349093931 scopus 로고    scopus 로고
    • Simplified antimalarial therapeutic monitoring: Using the day-7 drug level?
    • White NJ, Stepniewska K, Barnes K, et al.: Simplified antimalarial therapeutic monitoring: Using the day-7 drug level? Trends Parasitol 2008, 24:159-163.
    • (2008) Trends Parasitol , vol.24 , pp. 159-163
    • White, N.J.1    Stepniewska, K.2    Barnes, K.3
  • 16
    • 0037313684 scopus 로고    scopus 로고
    • Recrudescence in artesunate-treated patients with falciparum malaria is dependent on parasite burden not on parasite factors
    • Ittarat W, Pickard AL, Rattanasinganchan P, et al.: Recrudescence in artesunate-treated patients with falciparum malaria is dependent on parasite burden not on parasite factors. Am J Trop Med Hyg 2003, 68:147-152.
    • (2003) Am J Trop Med Hyg , vol.68 , pp. 147-152
    • Ittarat, W.1    Pickard, A.L.2    Rattanasinganchan, P.3
  • 17
    • 40049109285 scopus 로고    scopus 로고
    • Monitoring and deterring drug-resistant malaria in the era of combination therapy
    • Laufer MK, Djimde AA, Plowe CV: Monitoring and deterring drug-resistant malaria in the era of combination therapy. Am J Trop Med Hyg 2007, 77(6 Suupl):160-169.
    • (2007) Am J Trop Med Hyg , vol.77 , Issue.6 SUPPL. , pp. 160-169
    • Laufer, M.K.1    Djimde, A.A.2    Plowe, C.V.3
  • 18
    • 41949120362 scopus 로고    scopus 로고
    • Baseline in vitro efficacy of ACT component drugs on Plasmodium falciparum clinical isolates from Mali
    • Kaddouri H, Djimde A, Dama S, et al.: Baseline in vitro efficacy of ACT component drugs on Plasmodium falciparum clinical isolates from Mali. Int J Parasitol 2008, 38:791-798.
    • (2008) Int J Parasitol , vol.38 , pp. 791-798
    • Kaddouri, H.1    Djimde, A.2    Dama, S.3
  • 19
    • 34247134891 scopus 로고    scopus 로고
    • Comparison of a SYBR green I-based assay with a histidine-rich protein II enzymelinked immunosorbent assay for in vitro antimalarial drug efficacy testing and application to clinical isolates
    • Bacon DJ, Latour C, Lucas C, et al.: Comparison of a SYBR green I-based assay with a histidine-rich protein II enzymelinked immunosorbent assay for in vitro antimalarial drug efficacy testing and application to clinical isolates. Antimicrob Agents Chemother 2007, 51:1172-1178.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 1172-1178
    • Bacon, D.J.1    Latour, C.2    Lucas, C.3
  • 20
    • 40249112961 scopus 로고    scopus 로고
    • Performance and reliability of the SYBR green I based assay for the routine monitoring of susceptibility of Plasmodium falciparum clinical isolates
    • Rason MA, Randriantsoa T, Andrianantenaina H, et al.: Performance and reliability of the SYBR green I based assay for the routine monitoring of susceptibility of Plasmodium falciparum clinical isolates. Trans R Soc Trop Med Hyg 2008, 102:346-351.
    • (2008) Trans R Soc Trop Med Hyg , vol.102 , pp. 346-351
    • Rason, M.A.1    Randriantsoa, T.2    Andrianantenaina, H.3
  • 21
    • 2442655302 scopus 로고    scopus 로고
    • Molecular epidemiology of malaria in Cameroon. XX. Experimental studies on various factors of in vitro drug sensitivity assays using fresh isolates of Plasmodium falciparum
    • Basco LK: Molecular epidemiology of malaria in Cameroon. XX. Experimental studies on various factors of in vitro drug sensitivity assays using fresh isolates of Plasmodium falciparum. Am J Trop Med Hyg 2004, 70:474-480.
    • (2004) Am J Trop Med Hyg , vol.70 , pp. 474-480
    • Basco, L.K.1
  • 22
    • 35248823116 scopus 로고    scopus 로고
    • World Antimalarial Resistance Network (WARN) II: In vitro antimalarial drug susceptibility
    • Bacon DJ, Jambou R, Fandeur T, et al.: World Antimalarial Resistance Network (WARN) II: In vitro antimalarial drug susceptibility. Malar J 2007, 6:120.
    • (2007) Malar J , vol.6 , pp. 120
    • Bacon, D.J.1    Jambou, R.2    Fandeur, T.3
  • 23
    • 41949110686 scopus 로고    scopus 로고
    • In vitro evaluations of antimalarial drugs and their relevance to clinical outcomes
    • Ekland EH, Fidock DA: In vitro evaluations of antimalarial drugs and their relevance to clinical outcomes. Int J Parasitol 2008, 38:743-747.
    • (2008) Int J Parasitol , vol.38 , pp. 743-747
    • Ekland, E.H.1    Fidock, D.A.2
  • 24
    • 0001651897 scopus 로고
    • Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene
    • Bzik DJ, Li WB, Horii T, Inselburg J: Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene. Proc Natl Acad Sci U S A 1987, 84:8360-8364.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 8360-8364
    • Bzik, D.J.1    Li, W.B.2    Horii, T.3    Inselburg, J.4
  • 25
    • 0024338609 scopus 로고
    • Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum
    • Foote SJ, Thompson JK, Cowman AF, Kemp DJ: Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum. Cell 1989, 57:921-930.
    • (1989) Cell , vol.57 , pp. 921-930
    • Foote, S.J.1    Thompson, J.K.2    Cowman, A.F.3    Kemp, D.J.4
  • 26
    • 0028021624 scopus 로고
    • Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: Dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine
    • Brooks DR, Wang P, Read M, et al.: Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: Dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine. Eur J Biochem 1994, 224:397-405.
    • (1994) Eur J Biochem , vol.224 , pp. 397-405
    • Brooks, D.R.1    Wang, P.2    Read, M.3
  • 27
    • 0000841123 scopus 로고
    • Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria
    • Peterson DS, Walliker D, Wellems TE: Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. Proc Natl Acad Sci U S A 1988, 85:9114-9118.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 9114-9118
    • Peterson, D.S.1    Walliker, D.2    Wellems, T.E.3
  • 28
    • 0026328231 scopus 로고
    • Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7
    • Wellems TE, Walker-Jonah A, Panton LJ: Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7. Proc Natl Acad Sci U S A 1991, 88:3382-3386.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 3382-3386
    • Wellems, T.E.1    Walker-Jonah, A.2    Panton, L.J.3
  • 29
    • 0033636607 scopus 로고    scopus 로고
    • Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance
    • Fidock DA, Nomura T, Talley AK, et al.: Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance. Mol Cell 2000, 6:861-871.
    • (2000) Mol Cell , vol.6 , pp. 861-871
    • Fidock, D.A.1    Nomura, T.2    Talley, A.K.3
  • 30
    • 0030720799 scopus 로고    scopus 로고
    • Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance
    • Plowe CV, Cortese JF, Djimde A, et al.: Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance. J Infect Dis 1997, 176:1590-1596.
    • (1997) J Infect Dis , vol.176 , pp. 1590-1596
    • Plowe, C.V.1    Cortese, J.F.2    Djimde, A.3
  • 31
    • 0030801206 scopus 로고    scopus 로고
    • Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins
    • Wang P, Lee CS, Bayoumi R, et al.: Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins. Mol Biochem Parasitol 1997, 89:161-177.
    • (1997) Mol Biochem Parasitol , vol.89 , pp. 161-177
    • Wang, P.1    Lee, C.S.2    Bayoumi, R.3
  • 32
    • 0035945682 scopus 로고    scopus 로고
    • A molecular marker for chloroquine-resistant falciparum malaria
    • Djimde A, Doumbo OK, Cortese JF, et al.: A molecular marker for chloroquine-resistant falciparum malaria. N Engl J Med 2001, 344:257-263.
    • (2001) N Engl J Med , vol.344 , pp. 257-263
    • Djimde, A.1    Doumbo, O.K.2    Cortese, J.F.3
  • 33
    • 0036467612 scopus 로고    scopus 로고
    • Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malaria
    • Kublin JG, Dzinjalamala FK, Kamwendo DD, et al.: Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malaria. J Infect Dis 2002, 185:380-388.
    • (2002) J Infect Dis , vol.185 , pp. 380-388
    • Kublin, J.G.1    Dzinjalamala, F.K.2    Kamwendo, D.D.3
  • 34
    • 0035883813 scopus 로고    scopus 로고
    • Application of a molecular marker for surveillance of chloroquine-resistant falciparum malaria
    • Djimde A, Doumbo OK, Steketee RW, Plowe CV: Application of a molecular marker for surveillance of chloroquine-resistant falciparum malaria. Lancet 2001, 358:890-891.
    • (2001) Lancet , vol.358 , pp. 890-891
    • Djimde, A.1    Doumbo, O.K.2    Steketee, R.W.3    Plowe, C.V.4
  • 35
    • 0042860063 scopus 로고    scopus 로고
    • Artemisinins target the SERCA of Plasmodium falciparum
    • Eckstein-Ludwig U, Webb RJ, Van Goethem ID, et al.: Artemisinins target the SERCA of Plasmodium falciparum. Nature 2003, 424:957-961.
    • (2003) Nature , vol.424 , pp. 957-961
    • Eckstein-Ludwig, U.1    Webb, R.J.2    Van Goethem, I.D.3
  • 36
    • 28244477359 scopus 로고    scopus 로고
    • Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6
    • Jambou R, Legrand E, Niang M, et al.: Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6. Lancet 2005, 366:1960-1963.
    • (2005) Lancet , vol.366 , pp. 1960-1963
    • Jambou, R.1    Legrand, E.2    Niang, M.3
  • 37
    • 47349124330 scopus 로고    scopus 로고
    • No PfATPase6 S769N mutation found in Plasmodium falciparum isolates from China
    • Zhang G, Guan Y, Zheng B, et al.: No PfATPase6 S769N mutation found in Plasmodium falciparum isolates from China. Malar J 2008, 7:122.
    • (2008) Malar J , vol.7 , pp. 122
    • Zhang, G.1    Guan, Y.2    Zheng, B.3
  • 38
    • 33846600057 scopus 로고    scopus 로고
    • Molecular monitoring of Plasmodium falciparum resistance to artemisinin in Tanzania
    • Mugittu K, Genton B, Mshinda H, Beck HP: Molecular monitoring of Plasmodium falciparum resistance to artemisinin in Tanzania. Malar J 2006, 5:126.
    • (2006) Malar J , vol.5 , pp. 126
    • Mugittu, K.1    Genton, B.2    Mshinda, H.3    Beck, H.P.4
  • 39
    • 33847115335 scopus 로고    scopus 로고
    • In vitro assessment of artesunate, artemether and amodiaquine susceptibility and molecular analysis of putative resistance-associated mutations of Plasmodium falciparum from Sao Tome and Principe
    • Ferreira ID, Lopes D, Martinelli A, et al.: In vitro assessment of artesunate, artemether and amodiaquine susceptibility and molecular analysis of putative resistance-associated mutations of Plasmodium falciparum from Sao Tome and Principe. Trop Med Int Health 2007, 12:353-362.
    • (2007) Trop Med Int Health , vol.12 , pp. 353-362
    • Ferreira, I.D.1    Lopes, D.2    Martinelli, A.3
  • 40
    • 2142769136 scopus 로고    scopus 로고
    • Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number
    • Price RN, Uhlemann AC, Brockman A, et al.: Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number. Lancet 2004, 364:438-447.
    • (2004) Lancet , vol.364 , pp. 438-447
    • Price, R.N.1    Uhlemann, A.C.2    Brockman, A.3
  • 41
    • 33746302565 scopus 로고    scopus 로고
    • Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin
    • Sidhu AB, Uhlemann AC, Valderramos SG, et al.: Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin. J Infect Dis 2006, 194:528-535.
    • (2006) J Infect Dis , vol.194 , pp. 528-535
    • Sidhu, A.B.1    Uhlemann, A.C.2    Valderramos, S.G.3
  • 42
    • 33646360203 scopus 로고    scopus 로고
    • Real-time quantitative PCR with SYBR Green I detection for estimating copy numbers of nine drug resistance candidate genes in Plasmodium falciparum
    • Ferreira ID, Rosario VE, Cravo PV: Real-time quantitative PCR with SYBR Green I detection for estimating copy numbers of nine drug resistance candidate genes in Plasmodium falciparum. Malar J 2006, 5:1.
    • (2006) Malar J , vol.5 , pp. 1
    • Ferreira, I.D.1    Rosario, V.E.2    Cravo, P.V.3
  • 43
    • 35448959339 scopus 로고    scopus 로고
    • Pharmacologic advances in the global control and treatment of malaria: Combination therapy and resistance
    • Nyunt MM, Plowe CV: Pharmacologic advances in the global control and treatment of malaria: Combination therapy and resistance. Clin Pharmacol Ther 2007, 82:601-605.
    • (2007) Clin Pharmacol Ther , vol.82 , pp. 601-605
    • Nyunt, M.M.1    Plowe, C.V.2
  • 44
    • 42949105447 scopus 로고    scopus 로고
    • Pharmacokinetic determinants of the window of selection for antimalarial drug resistance
    • Stepniewska K, White NJ: Pharmacokinetic determinants of the window of selection for antimalarial drug resistance. Antimicrob Agents Chemother 2008, 52:1589-1596.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 1589-1596
    • Stepniewska, K.1    White, N.J.2
  • 45
    • 37549000986 scopus 로고    scopus 로고
    • A network to monitor antimalarial drug resistance: A plan for moving forward
    • Sibley CH, Barnes KI, Watkins WM, Plowe CV: A network to monitor antimalarial drug resistance: A plan for moving forward. Trends Parasitol 2008, 24:43-48.
    • (2008) Trends Parasitol , vol.24 , pp. 43-48
    • Sibley, C.H.1    Barnes, K.I.2    Watkins, W.M.3    Plowe, C.V.4


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