Telaprevir: A promising protease inhibitor for the treatment of hepatitis C virus infection

Current Medicinal Chemistry

Volumn 16, Issue 9, 2009, Pages 1115-1121

  Gentile, I ^a   Viola, C ^a   Borgia, F ^a,b   Castaldo, G ^a,b   Borgia, G ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

Author keywords

Clinical trial; Combination therapy; HCV; PEG IFN; Resistance; Ribavirin; SVR; Telaprevir

Indexed keywords

BOCEPREVIR; CILUPREVIR; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4A; NONSTRUCTURAL PROTEIN 4B; NONSTRUCTURAL PROTEIN 5A; NONSTRUCTURAL PROTEIN 5B; PEGINTERFERON; PEGINTERFERON ALPHA; PEGINTERFERON ALPHA2A; PLACEBO; RIBAVIRIN; RITONAVIR; TELAPREVIR; VIRUS RNA;

ANEMIA; ANTIVIRAL ACTIVITY; ANTIVIRAL RESISTANCE; AREA UNDER THE CURVE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; DIARRHEA; DOSAGE SCHEDULE COMPARISON; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG ERUPTION; DRUG HALF LIFE; DRUG LIVER LEVEL; DRUG METABOLISM; DRUG POTENTIATION; DRUG SAFETY; DRUG SENSITIVITY; DRUG TOLERABILITY; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; DRY SKIN; ENZYME INHIBITION; FATIGUE; GASTROINTESTINAL DISEASE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LOADING DRUG DOSE; MONOTHERAPY; NAUSEA; NONHUMAN; PRURITUS; REVIEW; UNSPECIFIED SIDE EFFECT; VIRUS GENOME;

ANTIVIRAL AGENTS; HEPACIVIRUS; HEPATITIS C; HUMANS; OLIGOPEPTIDES; PROTEASE INHIBITORS;

EID: 65649142019     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986709787581789     Document Type: Review

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