Expression of sphingosine kinase 2 in synovial fibroblasts of rheumatoid arthritis contributing to apoptosis by a sphingosine analogue, FTY720

Pathology International

Volumn 59, Issue 6, 2009, Pages 382-389

  Kamada, Kazuo ^b   Arita, Norimasa ^b   Tsubaki, Takahito ^c   Takubo, Nobuo ^d   Fujino, Takahiro ^e   Soga, Yoshiko ^b   Miyazaki, Tatsuhiko ^b   Yamamoto, Haruyasu ^a   Nose, Masato ^a,b  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Departments of Pathogenomics   (Japan)

^c EHIME PREFECTURAL CENTRAL HOSPITAL   (Japan)

^d Takubo Rheumatism and Orthopedics Clinic

^e EHIME UNIVERSITY   (Japan)

Author keywords

Apoptosis; Early stage rheumatoid arthritis; Epidermal growth factor; Polymerase chain reaction array; Sphingosine 1 phosphate

Indexed keywords

FINGOLIMOD; NUCLEAR PROTEIN; SPHINGOSINE DERIVATIVE; SPHINGOSINE KINASE 2;

APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL SURFACE; CELL TRANSFER; CONTROLLED STUDY; CYTOPLASM; EMBRYO; FIBROBLAST; GENE EXPRESSION; GENETIC PREDISPOSITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; KNEE; MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; SYNOVIUM;

APOPTOSIS; ARTHRITIS, RHEUMATOID; BLOTTING, WESTERN; CELLS, CULTURED; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; IN SITU NICK-END LABELING; MICROSCOPY, CONFOCAL; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROPYLENE GLYCOLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPHINGOSINE; SYNOVIAL MEMBRANE;

EID: 65649137319     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/j.1440-1827.2009.02381.x     Document Type: Article

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