메뉴 건너뛰기




Volumn 515, Issue , 2009, Pages 137-150

Production of multicistronic HIV-1 based lentiviral vectors

Author keywords

2A cleavage factor; Bicistronic lentiviral vector; EGFP; HOXB4; IRES; MGMT; Monocistronic lentiviral vector; Multigene lentiviral vectors; Tricistronic lentiviral vector

Indexed keywords

ARTICLE; CELL LINE; FLOW CYTOMETRY; GENE TRANSFER; GENE VECTOR; GENETICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; INSTRUMENTATION; LENTIVIRINAE; METHODOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; REPORTER GENE; TISSUE CULTURE TECHNIQUE;

EID: 65649098724     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-59745-559-6_9     Document Type: Article
Times cited : (7)

References (14)
  • 1
    • 3042819538 scopus 로고    scopus 로고
    • Exploiting internal ribosome entry sites in gene therapy vector design
    • DOI 10.2174/1566523044578095
    • Ngoi, S.M., Chien, A.C. and Lee, C.G. Exploiting internal ribosome entry sites in gene therapy vector design, Curr. Gene Ther., 4: 15-31, 2004. (Pubitemid 38854943)
    • (2004) Current Gene Therapy , vol.4 , Issue.1 , pp. 15-31
    • Ngoi, S.M.1    Chien, A.C.2    Lee, C.G.L.3
  • 2
    • 0034170820 scopus 로고    scopus 로고
    • IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector
    • Mizuguchi, H., Xu, Z., Ishii-Watabe, A., Uchida , E. and Hayakawa, T. IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector, Mol. Ther., 1: 376-382, 2000.
    • (2000) Mol. Ther. , vol.1 , pp. 376-382
    • Mizuguchi, H.1    Xu, Z.2    Ishii-Watabe, A.3    Uchida, E.4    Hayakawa, T.5
  • 3
    • 0032501958 scopus 로고    scopus 로고
    • Co-expression of human adenosine deaminase and multidrug resistance using a bicistronic retroviral vector
    • Zhou, Y., Aran, J., Gottesman, M.M. and Pastan, I. Co-expression of human adenosine deaminase and multidrug resistance using a bicistronic retroviral vector, Hum. Gene Ther., 9: 287-293, 1998. (Pubitemid 28085016)
    • (1998) Human Gene Therapy , vol.9 , Issue.3 , pp. 287-293
    • Zhou, Y.I.1    Aran, J.2    Gottesman, M.M.3    Pastan, I.4
  • 4
    • 0034973713 scopus 로고    scopus 로고
    • Recombinant AAV vectors containing the foot and mouth disease virus 2A sequence confer efficient bicistronic gene expression in cultured cells and rat substantia nigra neurons
    • DOI 10.1038/sj.gt.3301469
    • Furler, S., Paterna, J.C., Weibel, M. and Bueler, H. Recombinant AAV vectors containing the foot and mouth disease virus 2A sequence confer efficient bicistronic gene expression in cultured cells and rat substantia nigra neurons, Gene Ther., 8: 864-873, 2001. (Pubitemid 32577191)
    • (2001) Gene Therapy , vol.8 , Issue.11 , pp. 864-873
    • Furler, S.1    Paterna, J.-C.2    Weibel, M.3    Bueler, H.4
  • 5
    • 0033030109 scopus 로고    scopus 로고
    • Use of the 2A sequence from foot-and-mouth disease virus in the generation of retroviral vectors for gene therapy
    • DOI 10.1038/sj.gt.3300811
    • de Felipe, P., Martin, V., Cortes, M.L., Ryan, M. and Izquierdo, M. Use of the 2A sequence from foot-and-mouth disease virus in the generation of retroviral vectors for gene therapy, Gene Ther., 6: 198-208, 1999. (Pubitemid 29089918)
    • (1999) Gene Therapy , vol.6 , Issue.2 , pp. 198-208
    • De Felipe, P.1    Martin, V.2    Cortes, M.L.3    Ryan, M.4    Izquierdo, M.5
  • 6
    • 0034990345 scopus 로고    scopus 로고
    • Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy
    • DOI 10.1038/sj.gt.3301447
    • Klump, H., Schiedlmeier, B., Vogt, B., Ryan, M., Ostertag, W. and Baum, C. Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy, Gene Ther., 8: 811-817, 2001. (Pubitemid 32509796)
    • (2001) Gene Therapy , vol.8 , Issue.10 , pp. 811-817
    • Klump, H.1    Schiedlmeier, B.2    Vogt, B.3    Ryan, M.4    Ostertag, W.5    Baum, C.6
  • 7
    • 0034663189 scopus 로고    scopus 로고
    • Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage-colony-stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce antileukemic immune responses
    • Stripecke, R., Cardoso, A.A., Pepper, K.A., Skelton, D.C., Yu, X.J., Mascarenhas, L., Weinberg, K.I., Nadler, L.M. and Kohn, D.B. Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage-colonystimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce antileukemic immune responses, Blood, 96: 1317-1326, 2000. (Pubitemid 30658459)
    • (2000) Blood , vol.96 , Issue.4 , pp. 1317-1326
    • Stripecke, R.1    Cardoso, A.A.2    Pepper, K.A.3    Skelton, D.C.4    Yu, X.-J.5    Mascarenhas, L.6    Weinberg, K.I.7    Nadler, L.M.8    Kohn, D.B.9
  • 8
    • 0033759915 scopus 로고    scopus 로고
    • Development of multigene and regulated lentivirus vectors
    • Reiser, J., Lai, Z., Zhang, X.Y. and Brady, R.O. Development of multigene and regulated lentivirus vectors, J. Virol., 74: 10589-10599, 2000.
    • (2000) J. Virol. , vol.74 , pp. 10589-10599
    • Reiser, J.1    Lai, Z.2    Zhang, X.Y.3    Brady, R.O.4
  • 9
    • 10744229841 scopus 로고    scopus 로고
    • Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells
    • DOI 10.1016/S1525-0016(03)00104-7
    • Yu, X., Zhan, X., D'Costa, J., Tanavde, V.M., Ye, Z., Peng, T., Malehorn, M.T., Yang, X., Civin, C.I. and Cheng, L. Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells, Mol. Ther., 7: 827-838, 2003. (Pubitemid 36790260)
    • (2003) Molecular Therapy , vol.7 , Issue.6 , pp. 827-838
    • Yu, X.1    Zhan, X.2    D'Costa, J.3    Tanavde, V.M.4    Ye, Z.5    Peng, T.6    Malehorn, M.T.7    Yang, X.8    Civin, C.I.9    Cheng, L.10
  • 10
    • 0037270391 scopus 로고    scopus 로고
    • A multigene lentiviral vector system based on differential splicing
    • Zhu, Y. and Planelles, V. A multigene lentiviral vector system based on differential splicing, Methods Mol. Med., 76: 433-448, 2003.
    • (2003) Methods Mol. Med. , vol.76 , pp. 433-448
    • Zhu, Y.1    Planelles, V.2
  • 11
    • 4143145142 scopus 로고    scopus 로고
    • Lentivirus-mediated expression of mutant MGMTP140K protects human CD34+ cells against the combined toxicity of O 6-benzylguanine and 1,3-Bis(2-chloroethyl)-nitrosourea or temozolomide
    • DOI 10.1089/1043034041648417
    • Chinnasamy, D., Fairbairn, L.J., Neuenfeldt, J., Treisman, J.S., Hanson, J.P., Jr., Margison, G.P. and Chinnasamy, N. Lentivirus-mediated expression of mutant MGMTP140K protects human CD34+ cells against the combined toxicity of O6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide, Hum. Gene Ther., 15: 758-769, 2004. (Pubitemid 39095248)
    • (2004) Human Gene Therapy , vol.15 , Issue.8 , pp. 758-769
    • Chinnasamy, D.1    Fairbairn, L.J.2    Neuenfeldt, J.3    Treisman, J.S.4    Hanson Jr., J.P.5    Margison, G.P.6    Chinnasamy, N.7
  • 12
    • 33646561281 scopus 로고    scopus 로고
    • Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI
    • Chinnasamy, D., Milsom, M.D., Shaffer, J., Neuenfeldt, J., Shaaban, A.F., Margison, G.P., Fairbairn, L.J. and Chinnasamy, N. Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI, Virol. J., 3: 14, 2006.
    • (2006) Virol. J. , vol.3 , pp. 14
    • Chinnasamy, D.1    Milsom, M.D.2    Shaffer, J.3    Neuenfeldt, J.4    Shaaban, A.F.5    Margison, G.P.6    Fairbairn, L.J.7    Chinnasamy, N.8
  • 13
    • 0030819379 scopus 로고    scopus 로고
    • Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
    • Zufferey, R., Nagy, D., Mandel, R.J., Naldini, L. and Trono, D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo, Nat. Biotechnol., 15: 871-875, 1997.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 871-875
    • Zufferey, R.1    Nagy, D.2    Mandel, R.J.3    Naldini, L.4    Trono, D.5
  • 14
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini, L., Blomer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F.H., Verma, I.M. and Trono, D. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector, Science, 272: 263-267, 1996. (Pubitemid 26119138)
    • (1996) Science , vol.272 , Issue.5259 , pp. 263-267
    • Naldini, L.1    Blomer, U.2    Gallay, P.3    Ory, D.4    Mulligan, R.5    Gage, F.H.6    Verma, I.M.7    Trono, D.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.