Role of hepatitis B surface antigen in the development of hepatocellular carcinoma: Regulation of lymphoid enhancer-binding factor 1

Journal of Experimental and Clinical Cancer Research

Volumn 28, Issue 1, 2009, Pages

  Tian, Xiaochen ^a   Li, Jinjun ^b   Ma, Zhang Mei ^a   Zhao, Chao ^a   Wan, Da Fang ^b   Wen, Yu Mei ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI CANCER INSTITUTE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; HEPATITIS B SURFACE ANTIGEN; ISOPROTEIN; LYMPHOID ENHANCER FACTOR 1; MYC PROTEIN; WNT PROTEIN; MYC PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; DISEASE COURSE; HEPATITIS B VIRUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL; UPREGULATION; IMMUNOLOGY; LIVER TUMOR; METABOLISM; SIGNAL TRANSDUCTION;

CARCINOMA, HEPATOCELLULAR; CYCLIN D1; HEPATITIS B SURFACE ANTIGENS; HUMANS; LIVER NEOPLASMS; LYMPHOID ENHANCER-BINDING FACTOR 1; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-MYC; SIGNAL TRANSDUCTION; UP-REGULATION; WNT PROTEINS;

EID: 65549165472     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-28-58     Document Type: Article

References (37)

1. Hepatitis B virus infection: current status. P Ocama CK Opio WM Lee, Am J Med 2005 118 1413 10.1016/j.amjmed.2005.06.021 16378788 (Pubitemid 41832336)
2. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. D Lavanchy, J Viral Hepat 2004 11 97 107 10.1046/j.1365-2893.2003.00487.x 14996343 (Pubitemid 38365759)
3. Global control of hepatitis B virus infection. JH Kao DS Chen, Lancet Infect Dis 2002 2 395 403 10.1016/S1473-3099(02)00315-8 12127351 (Pubitemid 34693257)
4. Hepatitis B virus infection. WM Lee, N Engl J Med 1997 337 1733 1745 10.1056/NEJM199712113372406 9392700
5. Hepatitis B virus infection - natural history and clinical consequences. D Ganem AM Prince, N Engl J Med 2004 350 1118 1129 10.1056/NEJMra031087 15014185 (Pubitemid 38298992)
6. Hepatoma in an HBsAg carrier - seven years after perinatal infection. RP Beasley IS Shiao TC Wu LY Hwang, J Pediatr 1982 101 83 84 10.1016/S0022-3476(82) 80190-X 6283055 (Pubitemid 12078183)
7. Hepatitis B virus-induced oncogenesis. J Lupberger E Hildt, World J Gastroenterol 2007 13 74 81 17206756 (Pubitemid 46165464)
8. Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. FV Chisari K Klopchin T Moriyama C Pasquinelli HA Dunsford S Sell CA Pinkert RL Brinster RD Palmiter, Cell 1989 59 1145 1156 10.1016/0092-8674(89)90770-8 2598264 (Pubitemid 20024625)
9. The PreS2 activator MHBs(t) of hepatitis B virus activates c-raf-1/Erk2 signaling in transgenic mice. E Hildt B Munz G Saher K Reifenberg PH Hofschneider, Embo J 2002 21 525 535 11847101 10.1093/emboj/21.4.525 (Pubitemid 34174034)
10. Gene-expression profiles of a hepatitis B small surface antigen-secreting cell line reveal upregulation of lymphoid enhancer-binding factor 1. X Tian C Zhao J Ren ZM Ma YH Xie YM Wen, J Gen Virol 2007 88 2966 2976 10.1099/vir.0.83108-0 17947518 (Pubitemid 350131233)
11. A PCR primer bank for quantitative gene expression analysis. X Wang B Seed, Nucleic Acids Res 2003 31 e154 14654707 10.1093/nar/gng154
12. Alterations of lymphoid enhancer factor-1 isoform expression in solid tumors and acute leukemias. W Wang P Ji B Steffen R Metzger PM Schneider H Halfter M Schrader WE Berdel H Serve C Muller-Tidow, Acta Biochim Biophys Sin (Shanghai) 2005 37 173 180 10.1111/j.1745-7270.2005.00023.x 15756419 (Pubitemid 40720561)
13. Estimates of the worldwide incidence of 25 major cancers in 1990. DM Parkin P Pisani J Ferlay, Int J Cancer 1999 80 827 841 10.1002/(SICI)1097- 0215(19990315)80:6<827::AID-IJC6>3.0.CO;2-P 10074914
14. Hepatocellular carcinoma. JM Llovet A Burroughs J Bruix, Lancet 2003 362 1907 1917 10.1016/S0140-6736(03)14964-1 14667750 (Pubitemid 37518510)
15. Epidemiology of hepatocellular carcinoma. FX Bosch J Ribes R Cleries M Diaz, Clin Liver Dis 2005 9 191 211 v 10.1016/j.cld.2004.12.009 15831268 (Pubitemid 40501996)
16. Proteomic analysis of cellular protein alterations using a hepatitis B virus-producing cellular model. A Tong L Wu Q Lin QC Lau X Zhao J Li P Chen L Chen H Tang C Huang YQ Wei, Proteomics 2008 8 2012 2023 10.1002/pmic.200700849 18491315
17. Hepatitis B virus and hepatocellular carcinoma. P Arbuthnot M Kew, Int J Exp Pathol 2001 82 77 100 10.1111/j.1365-2613.2001.iep178.x 11454100
18. COOH-terminal truncated HBV X protein plays key role in hepatocarcinogenesis. NF Ma SH Lau L Hu D Xie J Wu J Yang Y Wang MC Wu J Fung X Bai, Clin Cancer Res 2008 14 5061 5068 10.1158/1078-0432.CCR-07-5082 18698024
19. Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls. J Benn RJ Schneider, Proc Natl Acad Sci USA 1995 92 11215 11219 7479968 10.1073/pnas.92.24.11215
20. Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma. MA Feitelson LX Duan, Am J Pathol 1997 150 1141 1157 9094970
21. The hepatitis B virus protein MHBs(t) sensitizes hepatoma cells to TRAIL-induced apoptosis through ERK2. X Liang J Du Y Liu M Cui C Ma L Han Z Qu Z Zhang Z Sun L Zhang, Apoptosis 2007 12 1827 1836 10.1007/s10495-007-0114-4 17701086
22. Hepatitis B virus pre-S mutants, endoplasmic reticulum stress and hepatocarcinogenesis. HC Wang W Huang MD Lai IJ Su, Cancer Sci 2006 97 683 688 10.1111/j.1349-7006.2006.00235.x 16863502 (Pubitemid 43983778)
23. Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes. HC Wang WT Chang WW Chang HC Wu W Huang HY Lei MD Lai N Fausto IJ Su, Hepatology 2005 41 761 770 10.1002/hep.20615 15726643 (Pubitemid 40462938)
24. Wnt/Frizzled signaling in hepatocellular carcinoma. HC Lee M Kim JR Wands, Front Biosci 2006 11 1901 1915 10.2741/1933 16368566
25. Hepatocellular carcinoma: molecular pathways and new therapeutic targets. LR Roberts GJ Gores, Semin Liver Dis 2005 25 212 225 10.1055/s-2005-871200 15918149
26. Caught up in a Wnt storm: Wnt signaling in cancer. RH Giles JH van Es H Clevers, Biochim Biophys Acta 2003 1653 1 24 12781368
27. Wnt signalling in stem cells and cancer. T Reya H Clevers, Nature 2005 434 843 850 10.1038/nature03319 15829953
28. Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. A de La Coste B Romagnolo P Billuart CA Renard MA Buendia O Soubrane M Fabre J Chelly C Beldjord A Kahn C Perret, Proc Natl Acad Sci USA 1998 95 8847 8851 9671767 10.1073/pnas.95.15.8847
29. Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma. A Bengochea MM de Souza L Lefrancois E Le Roux O Galy I Chemin M Kim JR Wands C Trepo P Hainaut, Br J Cancer 2008 99 143 150 10.1038/sj.bjc.6604422 18577996
30. Coordinated expression of cyclin D1 and LEF-1/TCF transcription factor is restricted to a subset of hepatocellular carcinoma. A Schmitt-Graeff V Ertelt-Heitzmann HP Allgaier M Olschewski R Nitschke S Haxelmans K Koelble J Behrens HE Blum, Liver Int 2005 25 839 847 10.1111/j.1478-3231.2005.01069.x 15998435
31. The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing. K Hovanes TW Li ML Waterman, Nucleic Acids Res 2000 28 1994 2003 10756202 10.1093/nar/28.9.1994
32. Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. K Hovanes TW Li JE Munguia T Truong T Milovanovic J Lawrence Marsh RF Holcombe ML Waterman, Nat Genet 2001 28 53 57 10.1038/88264 11326276
33. Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells. MY Cha CM Kim YM Park WS Ryu, Hepatology 2004 39 1683 1693 10.1002/hep.20245 15185310
34. Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin. Q Ding W Xia JC Liu JY Yang DF Lee J Xia G Bartholomeusz Y Li Y Pan Z Li, Mol Cell 2005 19 159 170 10.1016/j.molcel.2005. 06.009 16039586
35. The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. M Shtutman J Zhurinsky I Simcha C Albanese M Amico R Pestell Z Ben A ev, Proc Natl Acad Sci USA 1999 96 5522 5527 10318916 10.1073/pnas.96.10.5522
36. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. O Tetsu F McCormick, Nature 1999 398 422 426 10.1038/18884 10201372
37. Amplification of c-myc in hepatocellular carcinoma: correlation with clinicopathologic features, proliferative activity and p53 overexpression. S Kawate T Fukusato S Ohwada A Watanuki Y Morishita, Oncology 1999 57 157 163 10.1159/000012024 10461064