메뉴 건너뛰기




Volumn 57, Issue 2, 1999, Pages 157-163

Amplification of c-myc in hepatocellular carcinoma: Correlation with clinicopathologic features, proliferative activity and p53 overexpression

Author keywords

Argyrophilic nucleolar organizer regions; c myc amplification; MIB 1; p53; Polymerase chain reaction

Indexed keywords

ALPHA FETOPROTEIN; DOPAMINE 2 RECEPTOR; FORMALDEHYDE; KI 67 ANTIGEN; MONOCLONAL ANTIBODY KI 67; PROTEIN P53;

EID: 0032820507     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000012024     Document Type: Article
Times cited : (135)

References (36)
  • 1
    • 0003956004 scopus 로고
    • Principles of molecular cell biology of cancer: Oncogenes
    • DeVita VT Jr, Hellman S, Rosenberg SA : Philadelphia, Lippincott
    • Perkins AS, Van de Woude GF: Principles of molecular cell biology of cancer: Oncogenes; in DeVita VT Jr, Hellman S, Rosenberg SA (eds): Cancer: Principles and Practice of Oncology, ed 4. Philadelphia, Lippincott, 1993, pp 35-59.
    • (1993) Cancer: Principles and Practice of Oncology, Ed 4 , pp. 35-59
    • Perkins, A.S.1    Van De Woude, G.F.2
  • 3
    • 0021135561 scopus 로고
    • c-myc transcript is induced in rat liver at a very early stage of regeneration or by cycloheximide treatment
    • Makino R, Hayashi K, Sugimura T: c-myc transcript is induced in rat liver at a very early stage of regeneration or by cycloheximide treatment. Nature 1984;310:697-698.
    • (1984) Nature , vol.310 , pp. 697-698
    • Makino, R.1    Hayashi, K.2    Sugimura, T.3
  • 4
    • 0021912710 scopus 로고
    • Expression of c-Ki-ras, c-Ha-ras and c-myc in specific cell types during epatocarcinogenesis
    • Yaswen P, Goyette M, Shank PR, Fausto N: Expression of c-Ki-ras, c-Ha-ras and c-myc in specific cell types during hepatocarcinogenesis. Mol Cell Biol 1985;5:780-786.
    • (1985) Mol Cell Biol , vol.5 , pp. 780-786
    • Yaswen, P.1    Goyette, M.2    Shank, P.R.3    Fausto, N.4
  • 5
    • 0027182756 scopus 로고
    • Analysis of ODC and c-myc gene expression in hepatocellular carcinoma by in situ hybridization and immunohistochemistry
    • Gan FY, Gesell MS, Alousi M, Luk GD: Analysis of ODC and c-myc gene expression in hepatocellular carcinoma by in situ hybridization and immunohistochemistry. J Histochem Cytochem 1993;41:1185-1196.
    • (1993) J Histochem Cytochem , vol.41 , pp. 1185-1196
    • Gan, F.Y.1    Gesell, M.S.2    Alousi, M.3    Luk, G.D.4
  • 6
    • 0025773533 scopus 로고
    • c-fos and c-myc oncoprotein expression in human hepatocellular carcinomas.
    • Arbuthnot P, Kew M, Fitschen W: c-fos and c-myc oncoprotein expression in human hepatocellular carcinomas. Anticancer Res 1991;11: 921-924.
    • (1991) Anticancer Res , vol.11 , pp. 921-924
    • Arbuthnot, P.1    Kew, M.2    Fitschen, W.3
  • 7
    • 0025367299 scopus 로고
    • The expression of c-myc and c-N-ras in human cirrhotic livers, hepatocellular carcinomas and liver tissue surrounding the tumors
    • Zhang XK, Huang DP, Qiu DK, Chiu JF: The expression of c-myc and c-N-ras in human cirrhotic livers, hepatocellular carcinomas and liver tissue surrounding the tumors. Oncogene 1990;5:909-914.
    • (1990) Oncogene , vol.5 , pp. 909-914
    • Zhang, X.K.1    Huang, D.P.2    Qiu, D.K.3    Chiu, J.F.4
  • 8
    • 0027427539 scopus 로고
    • Comparative analysis of p53 and c-myc expression and cell proliferation in human hepatocellular carcinoma: An enhanced immunohistochemical approach
    • Saegusa M, Takano Y, Kishimoto H, Wakabayashi G, Nohga K, Okudaira M: Comparative analysis of p53 and c-myc expression and cell proliferation in human hepatocellular carcinoma: An enhanced immunohistochemical approach. J Cancer Res Clin Oncol 1993;119: 737-744.
    • (1993) J Cancer Res Clin Oncol , vol.119 , pp. 737-744
    • Saegusa, M.1    Takano, Y.2    Kishimoto, H.3    Wakabayashi, G.4    Nohga, K.5    Okudaira, M.6
  • 9
    • 0028306247 scopus 로고
    • Molecular events in the pathogenesis of hepadnavirus-associated hepatocellular carcinoma
    • Robinson WS: Molecular events in the pathogenesis of hepadnavirus-associated hepatocellular carcinoma. Annu Rev Med 1994;45:297-323.
    • (1994) Annu Rev Med , vol.45 , pp. 297-323
    • Robinson, W.S.1
  • 10
    • 0344066818 scopus 로고
    • Amplification of the c-myc gene locus in a human hepatic tumor containing integrated hepatitis B virus DNA
    • Zuckerman AJ (ed): New York, Liss
    • Trowbridge R, Faga EA, Davison F, Eddleston ALWF, Williams R, Linskens MHK, Farzaneh E: Amplification of the c-myc gene locus in a human hepatic tumor containing integrated hepatitis B virus DNA; in Zuckerman AJ (ed): Viral Hepatitis and Liver Disease. New York, Liss, 1987, pp 764-768.
    • (1987) Viral Hepatitis and Liver Disease , pp. 764-768
    • Trowbridge, R.1    Faga, E.A.2    Davison, F.3    Alwf, E.4    Williams, R.5    Linskens, M.H.K.6    Farzaneh, E.7
  • 11
    • 0027682801 scopus 로고
    • Amplification of the c-myc gene in human hepatocellular carcinoma: Biologic significance
    • Peng SY, Lai PL, Hsu HC: Amplification of the c-myc gene in human hepatocellular carcinoma: Biologic significance. J Formos Med Assoc 1993;92:866-870.
    • (1993) J Formos Med Assoc , vol.92 , pp. 866-870
    • Peng, S.Y.1    Lai, P.L.2    Hsu, H.C.3
  • 12
    • 0029874206 scopus 로고    scopus 로고
    • c-myc amplification in hepatocellular carcinoma predicts unfavorable prognosis
    • Abou-Elella A, Gramlich T, Fritsch C, Gansler T: c-myc amplification in hepatocellular carcinoma predicts unfavorable prognosis. Mod Pathol 1996;9:95-98.
    • (1996) Mod Pathol , vol.9 , pp. 95-98
    • Abou-Elella, A.1    Gramlich, T.2    Fritsch, C.3    Gansler, T.4
  • 13
    • 0024338294 scopus 로고
    • Detection of amplified oncogenes by differential polymerase chain reaction
    • Frye RA, Benz CC, Liu E: Detection of amplified oncogenes by differential polymerase chain reaction. Oncogene 1989;4:1153-1157.
    • (1989) Oncogene , vol.4 , pp. 1153-1157
    • Frye, R.A.1    Benz, C.C.2    Liu, E.3
  • 14
    • 0026545619 scopus 로고
    • Analysis of gene amplification in archival tissue by differential polymerase chain reaction
    • Neubauer A, Neubauer B, He M, Effert P, Iglehart D, Frye RA, Liu E: Analysis of gene amplification in archival tissue by differential polymerase chain reaction. Oncogene 1992;7: 1019-1025.
    • (1992) Oncogene , vol.7 , pp. 1019-1025
    • Neubauer, A.1    Neubauer, B.2    He, M.3    Effert, P.4    Iglehart, D.5    Frye, R.A.6    Liu, E.7
  • 15
    • 14744304015 scopus 로고
    • An improved method for semiquantification of gene amplification from archival material
    • Underwood MA, Barlett JMS, Cooke TG: An improved method for semiquantification of gene amplification from archival material. PCR Methods Appl 1994;4:178-184.
    • (1994) PCR Methods Appl , vol.4 , pp. 178-184
    • Underwood, M.A.1    Barlett, J.M.S.2    Cooke, T.G.3
  • 16
    • 78651053628 scopus 로고
    • Primary carcinoma of the liver. A study of 100 cases among 48900 necropsies
    • Edmondson HA, Steiner PE: Primary carcinoma of the liver. A study of 100 cases among 48900 necropsies. Cancer 1954;7:462-503.
    • (1954) Cancer , vol.7 , pp. 462-503
    • Edmondson, H.A.1    Steiner, P.E.2
  • 18
    • 0023095283 scopus 로고
    • Nuclear organizer regions in lymphomas
    • Crocker J, Nar P: Nuclear organizer regions in lymphomas. J Pathol 1987;151:111-118.
    • (1987) J Pathol , vol.151 , pp. 111-118
    • Crocker, J.1    Nar, P.2
  • 19
    • 0023701358 scopus 로고
    • Silver-stained nucleoli and nucleolar organizer region counts are of no prognostic value in thick cutaneous malignant melanoma
    • Howat AJ, Giri DD, Wright AL, Underwood JCE: Silver-stained nucleoli and nucleolar organizer region counts are of no prognostic value in thick cutaneous malignant melanoma. J Pathol 1988;156:227-232.
    • (1988) J Pathol , vol.156 , pp. 227-232
    • Howat, A.J.1    Giri, D.D.2    Wright, A.L.3    Underwood, J.C.E.4
  • 20
    • 0027265154 scopus 로고
    • New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope
    • Key G, Becker MHG, Baron B, Duchrow M, Schluter C, Flad HD, Gerdes J: New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope. Lab Invest 1993;68:629-636.
    • (1993) Lab Invest , vol.68 , pp. 629-636
    • Key, G.1    Becker, M.H.G.2    Baron, B.3    Duchrow, M.4    Schluter, C.5    Flad, H.D.6    Gerdes, J.7
  • 21
    • 0026769713 scopus 로고
    • An immunochemical analysis of human nuclear phosphoprotein p53: New monoclonal antibodies and epitope mapping using recombinant p53
    • Vojtesek B, Bartek J, Midgley CA, Lane DP. An immunochemical analysis of human nuclear phosphoprotein p53: New monoclonal antibodies and epitope mapping using recombinant p53. J Immunol Methods 1992;151: 237-244.
    • (1992) J Immunol Methods , vol.151 , pp. 237-244
    • Vojtesek, B.1    Bartek, J.2    Midgley, C.A.3    Lane, D.P.4
  • 22
    • 0024554738 scopus 로고
    • The general rules for the clinical and pathological study of primary liver cancer
    • Liver Cancer Study Group of Japan: The general rules for the clinical and pathological study of primary liver cancer. Jpn J Surg 1989;19:98-129.
    • (1989) Jpn J Surg , vol.19 , pp. 98-129
  • 23
    • 0027263201 scopus 로고
    • Amplification of c-myc but not of c-erbB-2 is associated with high proliferative capacity in breast cancer
    • Kreipe H, Feist H, Fischer L, Felgner J, Heidorn K, Mettler L, Parwaresch R: Amplification of c-myc but not of c-erbB-2 is associated with high proliferative capacity in breast cancer. Cancer Res 1993;53:1956-1961.
    • (1993) Cancer Res , vol.53 , pp. 1956-1961
    • Kreipe, H.1    Feist, H.2    Fischer, L.3    Felgner, J.4    Heidorn, K.5    Mettler, L.6    Parwaresch, R.7
  • 24
    • 0027346546 scopus 로고
    • The c-myc oncogene in tumor progression
    • Garte SJ: The c-myc oncogene in tumor progression. Crit Rev Oncog 1993;4:435-449.
    • (1993) Crit Rev Oncog , vol.4 , pp. 435-449
    • Garte, S.J.1
  • 25
    • 0022572014 scopus 로고
    • Alteration of myc, myb and rasHa proto-oncogenes in cancers are frequent and show clinical correlation
    • Yokota J, Yokota YT, Battifora H, Fevre CL, Cline MJ: Alteration of myc, myb and rasHa proto-oncogenes in cancers are frequent and show clinical correlation. Science 1986;231: 261-265.
    • (1986) Science , vol.231 , pp. 261-265
    • Yokota, J.1    Yokota, Y.T.2    Battifora, H.3    Fevre, C.L.4    Cline, M.J.5
  • 26
    • 0026517303 scopus 로고
    • Frequent amplification of c-myc in ground squirrel liver tumors associated with past or ongoing infection with a hepadnavirus
    • Transy C, Fourel G, Robinson WS, Tiollais P, Marion PL, Buendia MA: Frequent amplification of c-myc in ground squirrel liver tumors associated with past or ongoing infection with a hepadnavirus. Proc Natl Acad Sci USA 1992; 89:3874-3878.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3874-3878
    • Transy, C.1    Fourel, G.2    Robinson, W.S.3    Tiollais, P.4    Marion, P.L.5    Buendia, M.A.6
  • 27
    • 0027512210 scopus 로고
    • Frequent multiplication of the long arm of chromosome 8 in hepatocellular carcinoma
    • Fujiwara Y, Monden M, Mori T, Nakamura Y, Emi M: Frequent multiplication of the long arm of chromosome 8 in hepatocellular carcinoma. Cancer Res 1993;53:857-860.
    • (1993) Cancer Res , vol.53 , pp. 857-860
    • Fujiwara, Y.1    Monden, M.2    Mori, T.3    Nakamura, Y.4    Emi, M.5
  • 28
    • 0028113349 scopus 로고
    • Characteristics of human hepatocellular carcinoma cell lines (Hep-KANO) derived from a non-cirrhotic hepatitis B virus carrier
    • Baba M, Hasegawa H, Nakayabu M, Tamaki S, Watanabe S, Shima T, Suzuki S, Kusano I, Kamada N: Characteristics of human hepatocellular carcinoma cell lines (Hep-KANO) derived from a non-cirrhotic hepatitis B virus carrier. Jpn J Cancer Res 1994;85:1105-1111.
    • (1994) Jpn J Cancer Res , vol.85 , pp. 1105-1111
    • Baba, M.1    Hasegawa, H.2    Nakayabu, M.3    Tamaki, S.4    Watanabe, S.5    Shima, T.6    Suzuki, S.7    Kusano, I.8    Kamada, N.9
  • 30
    • 0027423064 scopus 로고
    • Hepatitis B and alterations of the p53 tumor suppressor gene in hepatocellular carcinoma
    • Goldblum JR, Bartos RE, Carr KA, Frank TS: Hepatitis B and alterations of the p53 tumor suppressor gene in hepatocellular carcinoma. Am J Surg Pathol 1993;17:1244-1251.
    • (1993) Am J Surg Pathol , vol.17 , pp. 1244-1251
    • Goldblum, J.R.1    Bartos, R.E.2    Carr, K.A.3    Frank, T.S.4
  • 32
    • 0026678007 scopus 로고
    • Quantitation of biological tumor markers (p53, myc, Ki-67 and DNA ploidy) by multiparameter flow cytometry in non-small cell lung cancer
    • Morkve O, Halvorsen OJ, Stangeland L, Gulsvik A, Laerum OD: Quantitation of biological tumor markers (p53, myc, Ki-67 and DNA ploidy) by multiparameter flow cytometry in non-small cell lung cancer. Int J Cancer 1992; 52:851-855.
    • (1992) Int J Cancer , vol.52 , pp. 851-855
    • Morkve, O.1    Halvorsen, O.J.2    Stangeland, L.3    Gulsvik, A.4    Laerum, O.D.5
  • 33
    • 0028217101 scopus 로고
    • Tumor suppressor genes, growth factor genes, and oncogenes in hepatitis B virus-associated hepatocellular carcinoma
    • Tabor E: Tumor suppressor genes, growth factor genes, and oncogenes in hepatitis B virus-associated hepatocellular carcinoma. J Med Virol 1994;42:357-365.
    • (1994) J Med Virol , vol.42 , pp. 357-365
    • Tabor, E.1
  • 34
    • 0027211792 scopus 로고
    • Gene amplification and tumor progression
    • Brison O: Gene amplification and tumor progression. Biochim Biophys Acta 1993;1155: 25-41.
    • (1993) Biochim Biophys Acta , vol.1155 , pp. 25-41
    • Brison, O.1
  • 36
    • 0031080353 scopus 로고    scopus 로고
    • Usefulness of monoclonal antibody Ki-67 as a prognostic factor of hepatocellular carcinoma
    • Yoshimoto J, Iwata T, Takamori S, Kojima K, Hutagawa S: Usefulness of monoclonal antibody Ki-67 as a prognostic factor of hepatocellular carcinoma. Int Hepatol Commun 1997;6: 209-218.
    • (1997) Int Hepatol Commun , vol.6 , pp. 209-218
    • Yoshimoto, J.1    Iwata, T.2    Takamori, S.3    Kojima, K.4    Hutagawa, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.