메뉴 건너뛰기




Volumn 16, Issue 6, 2009, Pages 573-583

Effect of periconceptional undernutrition in sheep on late gestation expression of mRNA and protein from genes involved in fetal adrenal steroidogenesis and placental prostaglandin production

Author keywords

Fetus; HPA axis; Nutrition; Placenta; Pregnancy

Indexed keywords

CORTICOTROPIN; CYTOCHROME P450C17; HYDROCORTISONE; MESSENGER RNA; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE 2; UNCLASSIFIED DRUG;

EID: 65549153577     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719109332827     Document Type: Article
Times cited : (11)

References (58)
  • 1
    • 0014346027 scopus 로고
    • Premature parturition after infusion of corticotrophin or cortisol into foetal lambs
    • Liggins GC Premature parturition after infusion of corticotrophin or cortisol into foetal lambs. J Endocrinol. 1968 ; 42: 323-329.
    • (1968) J Endocrinol , vol.42 , pp. 323-329
    • Liggins, G.C.1
  • 2
    • 0014524487 scopus 로고
    • Foetal plasma corticosteroids and the initiation of parturition in sheep
    • Basset JM, Thorburn GD Foetal plasma corticosteroids and the initiation of parturition in sheep. J Endocrinol. 1969 ; 44: 285-286.
    • (1969) J Endocrinol , vol.44 , pp. 285-286
    • Basset, J.M.1    Thorburn, G.D.2
  • 3
    • 0033709493 scopus 로고    scopus 로고
    • Endocrine and paracrine regulation of birth at term and preterm
    • Challis JRG, Matthews SG, Gibb W., Lye SJ Endocrine and paracrine regulation of birth at term and preterm. Endocr Rev. 2000 ; 21: 514-550.
    • (2000) Endocr Rev , vol.21 , pp. 514-550
    • Challis, J.R.G.1    Matthews, S.G.2    Gibb, W.3    Lye, S.J.4
  • 4
    • 0014623677 scopus 로고
    • Premature delivery of foetal lambs infused with glucocorticoids
    • Liggins GC Premature delivery of foetal lambs infused with glucocorticoids. J Endocrinol. 1969 ; 45: 515-523.
    • (1969) J Endocrinol , vol.45 , pp. 515-523
    • Liggins, G.C.1
  • 5
    • 0028039420 scopus 로고
    • The role of cortisol in preparing the fetus for birth
    • Liggins GC The role of cortisol in preparing the fetus for birth. Reprod Fertil Dev. 1994 ; 6: 141-150. (Pubitemid 2112770)
    • (1994) Reproduction, Fertility and Development , vol.6 , Issue.2 , pp. 141-150
    • Liggins, G.C.1
  • 6
    • 0242584821 scopus 로고    scopus 로고
    • A periconceptional nutritional origin for non-infectious preterm birth
    • Bloomfield FH, Oliver MH, Hawkins P., et al. A periconceptional nutritional origin for non-infectious preterm birth. Science. 2003 ; 300: 606.
    • (2003) Science , vol.300
    • Bloomfield, F.H.1    Oliver, M.H.2    Hawkins, P.3
  • 8
    • 0028962645 scopus 로고
    • Gestationalandlabour-associated changes in the relative abundance of prostaglandin G/H synthase-1 and -2 mRNA in the ovine placenta
    • Rice GE, Freed KA, Aitken MA, Jacobs RA Gestationalandlabour-associated changes in the relative abundance of prostaglandin G/H synthase-1 and -2 mRNA in the ovine placenta. J Mol Endocrinol. 1995 ; 14: 237-245.
    • (1995) J Mol Endocrinol , vol.14 , pp. 237-245
    • Rice, G.E.1    Freed, K.A.2    Aitken, M.A.3    Jacobs, R.A.4
  • 9
    • 0030053209 scopus 로고    scopus 로고
    • Localization and developmental changes in prostaglandin H synthase (PGHS) and PGHS messenger ribonucleic acid in ovine placenta throughout gestation
    • DOI 10.1095/biolreprod54.3.654
    • Gibb W., Matthews SG, Challis JR Localization and developmental changes in prostaglandin H synthase (PGHS) and PGHS messenger ribonucleic acid in ovine placenta throughout gestation. Biol Reprod. 1996 ; 54: 654-659. (Pubitemid 26070211)
    • (1996) Biology of Reproduction , vol.54 , Issue.3 , pp. 654-659
    • Gibb, W.1    Matthews, S.G.2    Challis, J.R.G.3
  • 12
    • 0024346061 scopus 로고
    • Maturation and activation of hypothalamic-pituitary-adrenal function in fetal sheep
    • Challis JR, Brooks AN Maturation and activation of hypothalamic- pituitary-adrenal function in fetal sheep. Endocr Rev. 1989 ; 10: 182-204. (Pubitemid 19151344)
    • (1989) Endocrine Reviews , vol.10 , Issue.2 , pp. 182-204
    • Challis, J.R.G.1    Brooks, A.N.2
  • 13
    • 0017085264 scopus 로고
    • Rapid increase of foetal corticosteroids after prostaglandin E2
    • Louis TM, Challis JR, Robinson JS, Thorburn GD Rapid increase of foetal corticosteroids after prostaglandin E2. Nature. 1976 ; 264: 797-799.
    • (1976) Nature , vol.264 , pp. 797-799
    • Louis, T.M.1    Challis, J.R.2    Robinson, J.S.3    Thorburn, G.D.4
  • 14
    • 0033677398 scopus 로고    scopus 로고
    • Altered fetal pituitary-adrenal function in the ovine fetus treated with RU486 and meloxicam, an inhibitor of prostaglandin synthase-II
    • McKeown KJ, Challis JR, Small C., et al. Altered fetal pituitary-adrenal function in the ovine fetus treated with RU486 and meloxicam, an inhibitor of prostaglandin synthase-II. Biol Reprod. 2000 ; 63: 1899-1904.
    • (2000) Biol Reprod , vol.63 , pp. 1899-1904
    • McKeown, K.J.1    Challis, J.R.2    Small, C.3
  • 16
    • 0026452468 scopus 로고
    • Quantification and cellular localization of ovine placental lactogen messenger ribonucleic acid expression during mid- and late gestation
    • Kappes SM, Warren WC, Pratt SL, Liang R., Anthony RV Quantification and cellular localization of ovine placental lactogen messenger ribonucleic acid expression during mid- and late gestation. Endocrinology. 1992 ; 131: 2829-2838.
    • (1992) Endocrinology , vol.131 , pp. 2829-2838
    • Kappes, S.M.1    Warren, W.C.2    Pratt, S.L.3    Liang, R.4    Anthony, R.V.5
  • 17
    • 0034163464 scopus 로고    scopus 로고
    • Placental lactogen as a regulator of luteal cells function during pregnancy in sheep
    • DOI 10.1016/S0093-691X(00)00236-3, PII S0093691X00002363
    • Gregoraszczuk EL, Zieba D., Wierzchos E., Murawski M., Gertler A. Placental lactogen as a regulator of luteal cells function during pregnancy in the sheep. Theriogenology. 2000 ; 53: 877-885. (Pubitemid 30151405)
    • (2000) Theriogenology , vol.53 , Issue.4 , pp. 877-885
    • Gregoraszczuk, E.L.1    Zieba, D.2    Wierzchos, E.3    Murawski, M.4    Gertler, A.5
  • 18
    • 0026132940 scopus 로고
    • Relations between maternal and fetal plasma concentrations of placental lactogen and placental and fetal weights in well-fed ewes
    • Schoknecht PA, Nobrega SN, Petterson JA, Ehrhardt RA, Sleptis R., Bell AW Relations between maternal and fetal plasma concentrations of placental lactogen and placental and fetal weights in well-fed ewes. J Anim Sci. 1991 ; 69: 1059-1063.
    • (1991) J Anim Sci , vol.69 , pp. 1059-1063
    • Schoknecht, P.A.1    Nobrega, S.N.2    Petterson, J.A.3    Ehrhardt, R.A.4    Sleptis, R.5    Bell, A.W.6
  • 20
    • 0019391023 scopus 로고
    • Fetal and maternal ovine placental lactogen during hyperglycaemia, hypoglycaemia and fasting
    • Brinsmead MW, Bancroft BJ, Thorburn GD, Waters MJ Fetal and maternal ovine placental lactogen during hyperglycaemia, hypoglycaemia and fasting. J Endocrinol. 1981 ; 90: 337-343. (Pubitemid 11060231)
    • (1981) Journal of Endocrinology , vol.90 , Issue.3 , pp. 337-343
    • Brinsmead, M.W.1    Bancroft, B.J.2    Thorburn, G.D.3    Waters, M.J.4
  • 21
    • 0026590570 scopus 로고
    • Current topic: The synepitheliochorial placenta of ruminants: Binucleate cell fusions and hormone production
    • Wooding FB Current topic: the synepitheliochorial placenta of ruminants: binucleate cell fusions and hormone production. Placenta. 1992 ; 13: 101-113.
    • (1992) Placenta , vol.13 , pp. 101-113
    • Wooding, F.B.1
  • 22
    • 0017043146 scopus 로고
    • Adrenocortical-related maturational events in the fetus
    • Liggins GC Adrenocortical-related maturational events in the fetus. Am J Obstet Gynecol. 1976 ; 126: 931-941.
    • (1976) Am J Obstet Gynecol , vol.126 , pp. 931-941
    • Liggins, G.C.1
  • 23
    • 0034527182 scopus 로고    scopus 로고
    • Fetal hypothalamic-pituitary adrenal (HPA) development and activation as a determinant of the timing of birth, and of postnatal disease
    • Challis J., Sloboda D., Mathews S., et al. Fetal hypothalamic-pituitary adrenal (HPA) development and activation as a determinant of the timing of birth, and of postnatal disease. Endocr Res. 2000 ; 26: 489-504. (Pubitemid 32053063)
    • (2000) Endocrine Research , vol.26 , Issue.4 , pp. 489-504
    • Challis, J.1    Sloboda, D.2    Matthews, S.3    Holloway, A.4    Alfaidy, N.5    Howe, D.6    Fraser, M.7    Newnham, J.8
  • 24
    • 0028903116 scopus 로고
    • Co-expression of two distinct isoforms of 11 beta-hydroxysteroid dehydrogenase in the ovine placenta
    • Yang K. Co-expression of two distinct isoforms of 11 beta-hydroxysteroid dehydrogenase in the ovine placenta. J Steroid Biochem Mol Bio. 1995 ; 52: 337-343.
    • (1995) J Steroid Biochem Mol Bio , vol.52 , pp. 337-343
    • Yang, K.1
  • 25
    • 0036240298 scopus 로고    scopus 로고
    • Impact of maternal undernutrition during the periconceptional period, fetal number, and fetal sex on the development of the hypothalamo-pituitary adrenal axis in sheep during late gestation
    • Edwards LJ, McMillen IC Impact of maternal undernutrition during the periconceptional period, fetal number, and fetal sex on the development of the hypothalamo-pituitary adrenal axis in sheep during late gestation. Biol Reprod. 2002 ; 66: 1562-1569. (Pubitemid 34462304)
    • (2002) Biology of Reproduction , vol.66 , Issue.5 , pp. 1562-1569
    • Edwards, L.J.1    McMillen, I.C.2
  • 26
    • 40849131144 scopus 로고    scopus 로고
    • Effects of twinning and periconceptional undernutrition on lategestationhypothalamic-pituitary-adrenal axis function in ovine pregnancy
    • Rumball CW, Oliver MH, Thorstensen EB, et al. Effects of twinning and periconceptional undernutrition on lategestationhypothalamic-pituitary-adrenal axis function in ovine pregnancy. Endocrinology. 2008 ; 149: 1163-1172.
    • (2008) Endocrinology , vol.149 , pp. 1163-1172
    • Rumball, C.W.1    Oliver, M.H.2    Thorstensen, E.B.3
  • 27
    • 15344351367 scopus 로고    scopus 로고
    • Periconceptional undernutrition alters growth trajectory and metabolic and endocrine responses to fasting in late-gestation fetal sheep
    • DOI 10.1203/01.PDR.0000155942.18096.9C
    • Oliver MH, Hawkins P., Harding JE Periconceptional undernutrition alters growth trajectory and metabolic and endocrine responses to fasting in late-gestation fetal sheep. Pediatr Res. 2005 ; 57: 591-598. (Pubitemid 40392520)
    • (2005) Pediatric Research , vol.57 , Issue.4 , pp. 591-598
    • Oliver, M.H.1    Hawkins, P.2    Harding, J.E.3
  • 28
    • 0001249876 scopus 로고
    • CIDR: A new progesterone-releasing intravaginal device for induction of estrus and cycle control in sheep and goats
    • DOI 10.1016/0378-4320(93)90111-4
    • Wheaton JE, Carlson KM, Windels HF, Johnston LJ CIDR: a new progesterone-releasing intravaginal device for induction of estrus and cycle control in sheep and goats. Anim Reprod Sci. 1993 ; 33: 127-141. (Pubitemid 223016651)
    • (1993) Animal Reproduction Science , vol.33 , Issue.1-4 , pp. 127-141
    • Wheaton, J.E.1    Carlson, K.M.2    Windels, H.F.3    Johnston, L.J.4
  • 29
    • 0025821034 scopus 로고
    • Growth and metabolism of the placenta after unilateral fetectomy in twin pregnant ewes
    • Vatnick I., Schoknecht PA, Darrigrand R., Bell AW Growth and metabolism of the placenta after unilateral fetectomy in twin pregnant ewes. J Dev Physiol. 1991 ; 15: 351-356.
    • (1991) J Dev Physiol , vol.15 , pp. 351-356
    • Vatnick, I.1    Schoknecht, P.A.2    Darrigrand, R.3    Bell, A.W.4
  • 30
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for general users and for biologist programmers
    • Krawetz S, Misener S, eds. Totowa, NJ: Humana Press;
    • Rozen S., Skaletsky HJ Primer3 on the WWW for general users and for biologist programmers. In: Krawetz S, Misener S, eds. Bioinformatics Methods and Protocols: Methods in Molecular Biology. Totowa, NJ: Humana Press; 2000: 365-386.
    • (2000) Bioinformatics Methods and Protocols: Methods in Molecular Biology , pp. 365-386
    • Rozen, S.1    Skaletsky, H.J.2
  • 31
    • 0036254541 scopus 로고    scopus 로고
    • Adrenocorticotrophic hormone (ACTH) stimulation of sheep fetal adrenal cortex can occur without increased expression of ACTH receptor (ACTH-R) mRNA
    • DOI 10.1071/RD01046
    • Carter AM, Petersen YM, Towstoless M., Andreasen D., Jensen BL Adrenocorticotrophic hormone (ACTH) stimulation of sheep fetal adrenal cortex can occur without increased expression of ACTH receptor (ACTH-R) mRNA. Reprod Fertil Dev. 2002 ; 14: 1-6. (Pubitemid 34506258)
    • (2002) Reproduction, Fertility and Development , vol.14 , Issue.1-2 , pp. 1-6
    • Carter, A.M.1    Petersen, Y.M.2    Towstoless, M.3    Andreasen, D.4    Jensen, B.L.5
  • 33
    • 34250868974 scopus 로고    scopus 로고
    • Human natural polyamine as an anti-inflammatory substance
    • King AE, Paltoo A., Kelly RW, Sallenave JM, Bocking AD, Challis JR Expression of natural antimicrobials by human placenta and fetal membranes. Placenta. 2007 ; 28: 161-169. (Pubitemid 46984250)
    • (2007) Biotherapy , vol.21 , Issue.3 , pp. 161-169
    • Soda, K.1
  • 34
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976 ; 72: 248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 36
    • 0032911089 scopus 로고    scopus 로고
    • Demonstration of in vivo mammogenic and lactogenic effects of recombinant ovine placental lactogen and mammogenic effect of recombinant ovine GH in ewes during artificial induction of lactation
    • Kann G., Delobelle-Deroide A., Belair L., Gertler A., Djiane J. Demonstration of in vivo mammogenic and lactogenic effects of recombinant ovine placental lactogen and mammogenic effect of recombinant ovine GH in ewes during artificial induction of lactation. J Endocrinol. 1999 ; 160: 365-377. (Pubitemid 29182828)
    • (1999) Journal of Endocrinology , vol.160 , Issue.3 , pp. 365-377
    • Kann, G.1    Delobelle-Deroide, A.2    Belair, L.3    Gertler, A.4    Djiane, J.5
  • 37
    • 0034565140 scopus 로고    scopus 로고
    • Active immunization of ewes against ovine placental lactogen increases birth weight of lambs and milk production with no adverse effect on conception rate
    • Leibovich H., Gertler A., Bazer FW, Gootwine E. Active immunization of ewes against ovine placental lactogen increases birth weight of lambs and milk production with no adverse effect on conception rate. Anim Reprod Sci. 2000 ; 64: 33-47.
    • (2000) Anim Reprod Sci , vol.64 , pp. 33-47
    • Leibovich, H.1    Gertler, A.2    Bazer, F.W.3    Gootwine, E.4
  • 38
    • 40049101847 scopus 로고    scopus 로고
    • Effects of twin pregnancy and periconceptional undernutrition on maternal metabolism, fetal growth and glucose-insulin axis function in ovine pregnancy
    • Rumball CW, Harding JE, Oliver MH, Bloomfield FH Effects of twin pregnancy and periconceptional undernutrition on maternal metabolism, fetal growth and glucose-insulin axis function in ovine pregnancy. J Physiol. 2008 ; 586: 1399-1411.
    • (2008) J Physiol , vol.586 , pp. 1399-1411
    • Rumball, C.W.1    Harding, J.E.2    Oliver, M.H.3    Bloomfield, F.H.4
  • 39
    • 0025970588 scopus 로고
    • Immunoreactive adrenocorticotrophin is present in the ovary and in particular the oocyte of several mammalian species
    • Jacobs RA, Oosterhuis J., Porter DG, Lobb DK, Yuzpe AA, Challis JR Immunoreactive adrenocorticotrophin is present in the ovary and in particular the oocyte of several mammalian species. J Reprod Fertil. 1991 ; 91: 285-291.
    • (1991) J Reprod Fertil , vol.91 , pp. 285-291
    • Jacobs, R.A.1    Oosterhuis, J.2    Porter, D.G.3    Lobb, D.K.4    Yuzpe, A.A.5    Challis, J.R.6
  • 40
    • 0017336877 scopus 로고
    • Studies on ovine placental lactogen secretion by homologous radioimmunoassay
    • Handwerger S., Crenshaw CJ, Maurer WF, et al. Studies on ovine placental lactogen secretion by homologous radioimmunoassay. J Endocrinol. 1977 ; 72: 27-34. (Pubitemid 8037760)
    • (1977) Journal of Endocrinology , vol.72 , Issue.1 , pp. 27-34
    • Handwerger, S.1    Crenshaw Jr., C.2    Maurer, W.F.3
  • 41
    • 0036629425 scopus 로고    scopus 로고
    • The effects of cortisol on the binucleate cell population in the ovine placenta during late gestation
    • Ward JW, Wooding FB, Fowden AL The effects of cortisol on the binucleate cell population in the ovine placenta during late gestation. Placenta. 2002 ; 23: 451-458.
    • (2002) Placenta , vol.23 , pp. 451-458
    • Ward, J.W.1    Wooding, F.B.2    Fowden, A.L.3
  • 43
    • 84980227318 scopus 로고
    • Ultrastructural studies of the placenta of the ewe: Phagocytosis of erythrocytes by the chorionic epithelium at the central depression of the cotyledon
    • Burton GJ, Samuel CA, Steven DH Ultrastructural studies of the placenta of the ewe: phagocytosis of erythrocytes by the chorionic epithelium at the central depression of the cotyledon. Q J Exp Physiol Cogn Med Sci. 1976 ; 61: 275-286.
    • (1976) Q J Exp Physiol Cogn Med Sci , vol.61 , pp. 275-286
    • Burton, G.J.1    Samuel, C.A.2    Steven, D.H.3
  • 44
    • 65549144179 scopus 로고    scopus 로고
    • Do alterations in placental 11b-hydroxysteriod dehydrogenase (11AZ2HSD) activities explain differences in fetal hypothalamic pituitary adrenal (HPA) function following periconceptional undernutrition or twinning in sheep?
    • Connor KL, van Zijl PL, Rumball CW, et al. Do alterations in placental 11b-hydroxysteriod dehydrogenase (11AZ2HSD) activities explain differences in fetal hypothalamic pituitary adrenal (HPA) function following periconceptional undernutrition or twinning in sheep? Reprod Sci. 2008 ; 15: 277A (Abstract).
    • (2008) Reprod Sci. , vol.15
    • Connor, K.L.1    Van Zijl, P.L.2    Rumball, C.W.3
  • 46
    • 0037206393 scopus 로고    scopus 로고
    • Maternal undernutrition throughout pregnancy increases adrenocorticotrophin receptor and steroidogenic acute regulatory protein gene expression in the adrenal gland of twin fetal sheep during late gestation
    • DOI 10.1016/S0303-7207(02)00256-3, PII S0303720702002563
    • Edwards LJ, Bryce AE, Coulter CL, McMillen IC Maternal undernutrition throughout pregnancy increases adrenocorticotrophin receptor and steroidogenic acute regulatory protein gene expression in the adrenal gland of twin fetal sheep during late gestation. Mol Cell Endocrinol. 2002 ; 196: 1-10. (Pubitemid 35254101)
    • (2002) Molecular and Cellular Endocrinology , vol.196 , Issue.1-2 , pp. 1-10
    • Edwards, L.J.1    Bryce, A.E.2    Coulter, C.L.3    McMillen, I.C.4
  • 47
    • 3242696079 scopus 로고    scopus 로고
    • Adrenocortical responsiveness is blunted in twin relative to singleton ovine fetuses
    • DOI 10.1113/jphysiol.2004.061796
    • Gardner DS, Jamall E., Fletcher AJ, Fowden AL, Giussani DA Adrenocortical responsiveness is blunted in twin relative to singleton ovine fetuses. J Physiol. 2004 ; 557: 1021-1032. (Pubitemid 38961633)
    • (2004) Journal of Physiology , vol.557 , Issue.3 , pp. 1021-1032
    • Gardner, D.S.1    Jamall, E.2    Fletcher, A.J.W.3    Fowden, A.L.4    Giussani, D.A.5
  • 49
    • 0035992890 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein expression is decreased in the adrenal gland of the growth-restricted sheep fetus during late gestation
    • Coulter CL, McMillen IC, Bird IM, Salkeld MD Steroidogenic acute regulatory protein expression is decreased in the adrenal gland of the growth-restricted sheep fetus during late gestation. Biol Reprod. 2002 ; 67: 584-590.
    • (2002) Biol Reprod , vol.67 , pp. 584-590
    • Coulter, C.L.1    McMillen, I.C.2    Bird, I.M.3    Salkeld, M.D.4
  • 50
    • 0035083131 scopus 로고    scopus 로고
    • The role of the pituitary gland and ACTH in the regulation of mRNAs encoding proteins essential for adrenal steroidogenesis in the late-gestation ovine fetus
    • DOI 10.1677/joe.0.1680475
    • Simmonds PJ, Phillips ID, Poore KR, Coghill ID, Young IR, Canny BJ The role of the pituitary gland and ACTH in the regulation of mRNAs encoding proteins essential for adrenal steroidogenesis in the late-gestation ovine fetus. J Endocrinol. 2001 ; 168: 475-485. (Pubitemid 32241892)
    • (2001) Journal of Endocrinology , vol.168 , Issue.3 , pp. 475-485
    • Simmonds, P.J.1    Phillips, I.D.2    Poore, K.R.3    Coghill, I.D.4    Young, I.R.5    Canny, B.J.6
  • 51
    • 0035065653 scopus 로고    scopus 로고
    • Developmental regulation of corticotrophin receptor gene expression in the adrenal gland of the ovine fetus and newborn lamb: Effects of hypoxia during late pregnancy
    • DOI 10.1677/joe.0.1690001
    • Fraser M., Braems GA, Challis JR Developmental regulation of corticotrophin receptor gene expression in the adrenal gland of the ovine fetus and newborn lamb: effects of hypoxia during late pregnancy. J Endocrinol. 2001 ; 169: 1-10. (Pubitemid 32273209)
    • (2001) Journal of Endocrinology , vol.169 , Issue.1 , pp. 1-10
    • Fraser, M.1    Braems, G.A.2    Challis, J.R.G.3
  • 53
    • 0034987734 scopus 로고    scopus 로고
    • Maternal undernutrition during early to midgestation programs tissue-specific alterations in the expression of the glucocorticoid receptor, 11β-hydroxysteroid dehydrogenase isoforms, and type 1 angiotensin II receptor in neonatal sheep
    • DOI 10.1210/en.142.7.2854
    • Whorwood CB, Firth KM, Budge H., Symonds ME Maternal undernutrition during early to midgestation programs tissue-specific alterations in the expression of the glucocorticoid receptor, 11beta-hydroxysteroid dehydrogenase isoforms, and type 1 angiotensin ii receptor in neonatal sheep. Endocrinology. 2001 ; 142: 2854-2864. (Pubitemid 32575520)
    • (2001) Endocrinology , vol.142 , Issue.7 , pp. 2854-2864
    • Whorwood, C.B.1    Firth, K.M.2    Budge, H.3    Symonds, M.E.4
  • 54
    • 3042772364 scopus 로고    scopus 로고
    • Alterations in placental 11β-hydroxysteroid dehydrogenase (11β HSD) activities and fetal cortisol:cortisone ratios induced by nutritional restriction prior to conception and at defined stages of gestation in ewes
    • McMullen S., Osgerby JC, Thurston LM, et al. Alterations in placental 11 beta-hydroxysteroid dehydrogenase (11 betaHSD) activities and fetal cortisol:cortisone ratios induced by nutritional restriction prior to conception and at defined stages of gestation in ewes. Reproduction. 2004 ; 127: 717-725. (Pubitemid 38878427)
    • (2004) Reproduction , vol.127 , Issue.6 , pp. 717-725
    • McMullen, S.1    Osgerby, J.C.2    Thurston, L.M.3    Gadd, T.S.4    Wood, P.J.5    Wathes, D.C.6    Michael, A.E.7
  • 55
    • 0020210085 scopus 로고
    • The role of the binucleate cell in ruminant placental structure
    • Wooding FB The role of the binucleate cell in ruminant placental structure. J Reprod Fertil Suppl. 1982 ; 31: 31-39.
    • (1982) J Reprod Fertil Suppl , vol.31 , pp. 31-39
    • Wooding, F.B.1
  • 56
    • 0018839593 scopus 로고
    • Electron microscopic localization of binucleate cells in the sheep placenta using phosphotungstic acid
    • Wooding FB Electron microscopic localization of binucleate cells in the sheep placenta using phosphotungstic acid. Biol Reprod. 1980 ; 22: 357-365. (Pubitemid 10115425)
    • (1980) Biology of Reproduction , vol.22 , Issue.2 , pp. 357-365
    • Wooding, F.B.P.1
  • 57
    • 0021164675 scopus 로고
    • Role of binucleate cells in fetomaternal cell fusion at implantation in the sheep
    • Wooding FB Role of binucleate cells in fetomaternal fusion at implantation in the sheep. Am J Anat. 1984 ; 170: 233-250. (Pubitemid 14117805)
    • (1984) American Journal of Anatomy , vol.170 , Issue.2 , pp. 233-250
    • Wooding, F.B.P.1
  • 58


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.