Developmental regulation of corticotrophin receptor gene expression in the adrenal gland of the ovine fetus and newborn lamb: Effects of hypoxia during late pregnancy

Journal of Endocrinology

Volumn 169, Issue 1, 2001, Pages 1-10

  Fraser, M ^a   Braems, G A ^a   Challis, J R G ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CORTICOTROPIN; CORTICOTROPIN RECEPTOR; GLUCOCORTICOID; MESSENGER RNA; OXYGEN;

ADOLESCENT; ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; CORTICOTROPIN RELEASE; DEVELOPMENT; FETUS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GESTATIONAL AGE; HORMONE BINDING; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; HYPOXIA; IN SITU HYBRIDIZATION; INHALATION; LABOR; LABORATORY; LAMB; MEASUREMENT; MOLECULAR CLONING; NEWBORN; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RECEPTOR GENE; REGULATORY MECHANISM; SHEEP; STEROIDOGENESIS; THIRD TRIMESTER PREGNANCY;

ADRENAL GLANDS; ADRENOCORTICOTROPIC HORMONE; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; BASE SEQUENCE; BLOTTING, NORTHERN; CATTLE; FEMALE; FETAL HYPOXIA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GESTATIONAL AGE; HYDROCORTISONE; IN SITU HYBRIDIZATION; MOLECULAR SEQUENCE DATA; PREGNANCY; PREGNANCY, ANIMAL; RECEPTORS, CORTICOTROPIN; RNA, MESSENGER; SEQUENCE HOMOLOGY; SHEEP;

EID: 0035065653     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1690001     Document Type: Article

References (46)

1. Effect of maternal betamethasone administration at midgestation on baboon fetal adrenal gland development and adrenocorticotropin receptor messenger ribonucleic acid expression
2. Threshold of hormonal and biophysical responses to acute hypoxemia in fetal sheep at different gestational ages
3. Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA
4. Foetal plasma corticosteroids and the initiation of parturition in the sheep
5. Angiotensin II acts via the type 1 receptor to inhibit 17á-hydroxylase cytochrome P450 expression in ovine adrenocortical cells
6. Mophometric analyses of adrenal gland growth in fetal and neonatal sheep. I The adrenal cortex
7. Differential regulation of proopiomelanocortin messenger ribonucleic acid in the pars distalis and pars intermedia of the pituitary gland after prolonged hypoxemia in fetal sheep
8. Gestational dependent changes in levels of mRNA encoding cortisol biosynthetic enzymes and insulin-like growth factor-II (IGF-II) in the adrenal gland of fetal sheep during prolonged hypoxemia
9. The mouse adrenocorticotropin receptor gene: Cloning and characterization of its promoter and evidence for a role for the orphan nuclear receptor steroidogenic factor 1
10. Regional adrenal blood flow responses to adrenocorticotropic hormone in fetal sheep
11. Maturation and activation of hypothalamic-pituitary-adrenal function in fetal sheep
12. Glucocorticoid enhancement of adrenocorticotropin-induced 3′,5′-cyclic adenosine monophosphate production by cultured ovine adrenocortical cells
13. Glucocorticoid induction of the maturation of ovine fetal adrenocortical cells
14. ACTH receptor levels in lamb adrenals at late gestation and early neonatal stages
15. Maturation of the ovine fetal adrenal gland: In vivo and in vitro studies
16. Gastrin releasing peptide is produced in the pregnant ovine uterus
17. The changing response pattern of sheep fetal adrenal cells throughout the course of gestation
18. Divergent changes in plasma adrenocorticotrophin (ACTH) and pituitary proopiomelanocortin (POMC) mRNA after cortisol administration to the ovine fetus late in gestation
19. ACTH peptides and the development of the fetal adrenal
20. Inhibition of fetal adrenal adrenocorticotropin receptor messenger ribonucleic acid expression by betamethasone administration to the baboon fetus in late gestation
21. Regulation of corticotropin and steroidogenic enzyme mRNAs in human fetal adrenal cells by corticotropin, angiotensin-II and transforming growth factor β1
22. Regulation of corticotropin receptor number and messenger RNA in cultured human adrenocortical cells by corticotropin and angiotensin II
23. The mechanism of initiation of parturition in the ewe
24. In vivo ACTH(1-24)-induced accumulation of cAMP by ovine fetal adrenal cells is inhibited by concomitant infusion of metapyrone
25. Activation of ovine fetal adrenal function by pulsatile or continuous administration of adrenocorticotropin-(1-24). I. Effects on fetal plasma corticosteroids
26. Time-trend analysis of plasma cortisol concentrations in the fetal sheep in relation to parturition
27. Regulation of CRH and AVP mRNA in the developing ovine hypothalamus: Effects of stress and glucocorticoids
28. Developmental and functional biology of the primate fetal adrenal cortex
29. Localization and regulation of corticotropin receptor expression in the midgestation human fetal adrenal cortex: Implications for in utero homeostasis
30. ACTH induces up-regulation of ACTH receptor mRNA in mouse and human adrenocortical cell lines
31. In vitro effect of insulin and insulin-like growth factor-I on cell multiplication and adrenocorticotropin responsiveness in fetal adrenal cells
32. Three steroidogenic factor-1 binding elements are required for constitutive and cAMP-regulated expression of the human adrenocorticotropin receptor gene
33. Changes in pituitary responses to synthetic ovine corticotrophin releasing factor in fetal sheep
34. Synergistic effects of corticotropin and insulin-like growth factor I on corticotropin receptors and corticotropin responsiveness in cultured bovine adrenocortical cells
35. Regulation of bovine adrenal cell corticotropin receptor mRNA levels by corticotropin (ACTH) and angiotensin II (A-II)
36. Regulation of the primate fetal adrenal cortex
37. Glucocorticoids enhance corticotropin receptor mRNA levels in ovine adrenocortical cells
38. Effects of transforming growth factor beta on ovine adrenocortical cells
39. Transforming growth factor beta treatment decreases ACTH receptors on ovine adrenocortical cells
40. In vivo evidence for increased adrenal sensitivity to adrenocorticotrophin-(1-24) in the lamb fetus late in gestation
41. Elevated levels of N-terminal pro-opiomelanocortin peptides in fetal sheep plasma may contribute to fetal adrenal gland development and the preparturient cortisol surge
42. Biological activity of adrenocorticotropic hormone precursors on ovine adrenal cells
43. Steroid hydroxylase gene expression in the ovine adrenal gland following ACTH infusion
44. Ontogeny of the expression of the ACTH receptor messenger RNA (mRNA) in sheep adrenals
45. The ontogeny and regulation of corticosteroid secretion by the ovine fetal adrenal
46. Regulation and function of the fetal adrenal gland in sheep