Active immunization of ewes against ovine placental lactogen increases birth weight of lambs and milk production with no adverse effect on conception rate

Animal Reproduction Science

Volumn 64, Issue 1-2, 2000, Pages 33-47

  Leibovich, H ^a   Gertler, A ^a   Bazer, F W ^b   Gootwine, E ^c  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^c VOLCANI CENTER   (Israel)

Author keywords

Immunization; Lamb production; Milk production; Placental lactogen; Sheep placenta

Indexed keywords

ANTIBODY; PLACENTA LACTOGEN; SOMATOMEDIN C;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIRTH WEIGHT; BLOOD; CELL DIVISION; CHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FERTILIZATION; IMMUNIZATION; IMMUNOLOGY; MALE; MILK; NEWBORN; NONPARAMETRIC TEST; PHYSIOLOGY; PREGNANCY; RADIOIMMUNOASSAY; SECRETION; SERODIAGNOSIS; SHEEP; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES; BIRTH WEIGHT; BLOTTING, WESTERN; CELL DIVISION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FERTILIZATION; IMMUNIZATION; INSULIN-LIKE GROWTH FACTOR I; MALE; MILK; NEUTRALIZATION TESTS; PLACENTAL LACTOGEN; PREGNANCY; RADIOIMMUNOASSAY; SHEEP; STATISTICS, NONPARAMETRIC;

EID: 0034565140     PISSN: 03784320     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4320(00)00198-6     Document Type: Article

References (47)

1. Effect of somatotropin during the dry period on subsequent milk production and induced secretion of somatotropin, prolactin and insulin pre- and post-partum
2. Placental-fetal hormonal interactions: Impact on fetal growth
3. The growth hormone prolactin gene family in ruminant placenta
4. Enhancement of bovine growth hormone activity in vivo by monoclonal antibodies
5. The fetal somatotropic axis during long term maternal undernutrition in sheep: Evidence for nutritional regulation in utero
6. Enhancement of bovine growth hormone activity by antibodies against growth hormone peptides
7. The transmission of passive immunity from mother to young
8. Radioimmunoassay for insulin-like growth factor-I: Solutions to some potential problems and pitfalls
9. Failure of fasting and changes in plasma metabolites to affect spontaneous fluctuations in plasma concentrations of ovine placental lactogen
10. Stimulation of body weight gain of mature female rat by bovine GH and bovine placental lactogen
11. Ruminant placental lactogens: Structure and biology
12. Differential effect of maternal ovine placental lactogen and growth hormone (GH) administration on GH receptor, insulin like growth factor (IGF)-I and IGF binding protein-3 gene expression in the pregnant and fetal sheep
13. Deficiency of human placental lactogen in an otherwise normal pregnancy
14. Effect of restriction of placental growth on the concentration of insulin, glucose and placental lactogen in the plasma of sheep
15. 2 node lymphoma cells by 12-o-tetradecanoyl-phorbol-13-acetate
16. Hormone ontogeny in the ovine fetus. II. Ovine chorionic somatomammotropin in mid- and late-gestation in the fetal and maternal circulation
17. Ruminant placental lactogens act as antagonists to homologous growth hormone receptors and as agonists to human or rabbit growth hormone receptors
18. Functional heterodimerization of prolactin and growth hormone receptors by ovine placental lactogen
19. Immunomodulation of the growth hormone-IGF-I axis
20. Demonstration of in vivo mammogenic and lactogenic effects of recombinant ovine placental lactogen and mammogenic effect of recombinant ovine GH in ewes during artificial induction of lactation
21. Quantification and cellular localization of ovine placental lactogen messenger ribonucleic acid expression during mid- and late-gestation
22. A comparison of growth hormone-induced mammogenesis in pregnant and lactating goats
23. Effects of recombinant ovine placental lactogen and recombinant ovine growth hormone on lamb growth and milk production in ewes
24. Maternal antibodies and immune responsiveness in growing lambs
25. Basic aspects of immunomodulation through active immunization
26. Growth-promoting effects of ovine placental lactogen (oPL) in young lambs: Comparison with bovine growth hormone provides evidence for a distinct effect of oPL on food intake
27. Enhancement of growth hormone (GH) activity by antisera prepared against analogues of an epitope peptide defined by a GH-enhancing monoclonal antibody
28. Absence of human placental lactogen in an otherwise uneventful pregnancy
29. The effect of ovine placental lactogen infusion on metabolites, insulin-like growth factors and binding proteins in the fetal sheep
30. Active immunization with a synthetic peptide region of growth hormone: Increased lean tissue growth
31. Principles of immunomodulation
32. Appropriate mathematical models for describing the lactation of dairy sheep
33. Human growth hormone fragments 1-43 and 44-191: In vitro somatogenic activity and receptor binding characteristics in human and nonprimate systems
34. Influence of fetal death and fetectomy on gestation and initiation of parturition in the ewe
35. Absence of human placental lactogen and placental growth hormone (hGH-V) during pregnancy: PCR analysis of the deletion
36. Large-scale preparation and characterization of recombinant ovine placental lactogen
37. Relations between maternal and fetal plasma concentrations of placental lactogen and placental and fetal weights in well-fed ewes
38. Kinetics of placental lactogen in mid- and late-gestation ovine fetuses
39. Effect of Chronic infusion of placental lactogen on ovine fetal growth in late gestation
40. Effects of recombinant ovine interferon tau, placental lactogen and growth hormone on the ovine uterus
41. Growth and subsequent lactation in primigravid Holstein heifers after prepartum bovine somatotropin treatment
42. Effect of prepartum bovine somatotropin in primigravid ewes on mammogenesis, milk production, and hormone concentrations
43. Indication of different lactogen and somatogen binding sites in the human growth hormone molecule as probed with monoclonal antibodies
44. Eletrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
45. Immunological effect of a synthetic growth hormone peptide on the growth performance in swine
46. An examination of the proposed roles of placental lactogen in the ewe by means of antibody neutralization