-
1
-
-
34250359779
-
Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease
-
Aleksunes, L. M., and Manautou, J. E. (2007). Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease. Toxicol. Pathol. 35, 459-473.
-
(2007)
Toxicol. Pathol
, vol.35
, pp. 459-473
-
-
Aleksunes, L.M.1
Manautou, J.E.2
-
2
-
-
0021832807
-
Purification of major basic glutathione transferase isoenzymes from rat liver by use of affinity chromatography and fast protein liquid chromatofocusing
-
Alin, P., Jensson, H., Guthenberg, C., Danielson, U. H., Tahir, M. K., and Mannervik, B. (1985). Purification of major basic glutathione transferase isoenzymes from rat liver by use of affinity chromatography and fast protein liquid chromatofocusing. Anal. Biochem. 146 313-320.
-
(1985)
Anal. Biochem
, vol.146
, pp. 313-320
-
-
Alin, P.1
Jensson, H.2
Guthenberg, C.3
Danielson, U.H.4
Tahir, M.K.5
Mannervik, B.6
-
3
-
-
0035875447
-
Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust
-
Aoki, Y., Sato, H., Nishimura, N., Takahashi, S., Itoh, K., and Yamamoto, M. (2001). Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust. Toxicol. Appl. Pharmacol. 173, 154-160.
-
(2001)
Toxicol. Appl. Pharmacol
, vol.173
, pp. 154-160
-
-
Aoki, Y.1
Sato, H.2
Nishimura, N.3
Takahashi, S.4
Itoh, K.5
Yamamoto, M.6
-
4
-
-
0024499938
-
Relation between biliary glutathione excretion and bile acid-independent bile flow
-
Ballatori, N., and Truong, A. T. (1989). Relation between biliary glutathione excretion and bile acid-independent bile flow. Am. J. Physiol. 256, G22-G30.
-
(1989)
Am. J. Physiol
, vol.256
-
-
Ballatori, N.1
Truong, A.T.2
-
5
-
-
0026497882
-
Glutathione as a primary osmotic driving force in hepatic bile formation
-
Ballatori, N., and Truong, A. T. (1992). Glutathione as a primary osmotic driving force in hepatic bile formation. Am. J. Physiol. 263, G617-G624.
-
(1992)
Am. J. Physiol
, vol.263
-
-
Ballatori, N.1
Truong, A.T.2
-
6
-
-
0242666198
-
Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/ accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:qUinone oxidoreductase-1 gene expression
-
Bloom, D. A., and Jaiswal, A. K. (2003). Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/ accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:qUinone oxidoreductase-1 gene expression. J. Biol. Chem. 278, 44675-44682.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 44675-44682
-
-
Bloom, D.A.1
Jaiswal, A.K.2
-
7
-
-
0006498604
-
The removal of bromsulphthalein from blood plasma by the liver of the rat
-
Brauer, R. W., and Pessotti, R. L. (1949). The removal of bromsulphthalein from blood plasma by the liver of the rat. J. Pharmacol. Exp. Ther. 97, 358-370.
-
(1949)
J. Pharmacol. Exp. Ther
, vol.97
, pp. 358-370
-
-
Brauer, R.W.1
Pessotti, R.L.2
-
8
-
-
0035188883
-
Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3
-
Cattori, V., van Montfoort, J. E., Stieger, B., Landmann, L., Meijer, D. K., Winterhalter, K. H., Meier, P. J., and Hagenbuch, B. (2001). Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3. Pflugers Arch. 443, 188-195.
-
(2001)
Pflugers Arch
, vol.443
, pp. 188-195
-
-
Cattori, V.1
van Montfoort, J.E.2
Stieger, B.3
Landmann, L.4
Meijer, D.K.5
Winterhalter, K.H.6
Meier, P.J.7
Hagenbuch, B.8
-
9
-
-
0030451213
-
NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development
-
Chan, K., Lu, R., Chang, J. C., and Kan, Y. W. (1996). NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development. Proc. Natl. Acad. Sci. U.S.A. 93, 13943-13948.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A
, vol.93
, pp. 13943-13948
-
-
Chan, K.1
Lu, R.2
Chang, J.C.3
Kan, Y.W.4
-
10
-
-
78651185582
-
The importance of conjugation with glutathione for sulfobromophthalein sodium (Bsp) transfer from blood to bile
-
Combes, B. (1965). The importance of conjugation with glutathione for sulfobromophthalein sodium (Bsp) transfer from blood to bile. J. Clin. Invest. 44, 1214-1224.
-
(1965)
J. Clin. Invest
, vol.44
, pp. 1214-1224
-
-
Combes, B.1
-
11
-
-
2442677441
-
Conjugation of sulfobromophthalein sodium with glutathione in thioether linkage by the rat
-
Combes, B., and Stakelum, G. S. (1960). Conjugation of sulfobromophthalein sodium with glutathione in thioether linkage by the rat. J. Clin. Invest. 39, 1214-1222.
-
(1960)
J. Clin. Invest
, vol.39
, pp. 1214-1222
-
-
Combes, B.1
Stakelum, G.S.2
-
12
-
-
0000112444
-
A liver enzyme that conjugates sulfobromophthalein sodium with glutathione
-
Combes, B., and Stakelum, G. S. (1961). A liver enzyme that conjugates sulfobromophthalein sodium with glutathione. J. Clin. Invest. 40, 981-988.
-
(1961)
J. Clin. Invest
, vol.40
, pp. 981-988
-
-
Combes, B.1
Stakelum, G.S.2
-
13
-
-
0034753042
-
Vectorial transport by double-transfected cells expressing the human uptake transporter SLC21A8 and the apical export pump ABCC2
-
Cui, Y., Konig, J., and Keppler, D. (2001). Vectorial transport by double-transfected cells expressing the human uptake transporter SLC21A8 and the apical export pump ABCC2. Mol. Pharmacol. 60, 934-943.
-
(2001)
Mol. Pharmacol
, vol.60
, pp. 934-943
-
-
Cui, Y.1
Konig, J.2
Keppler, D.3
-
14
-
-
0035153227
-
High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes
-
Enomoto, A., Itoh, K., Nagayoshi, E., Haruta, J., Kimura, T., O'Connor, T., Harada, T., and Yamamoto, M. (2001). High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes. Toxicol. Sci. 59, 169-177.
-
(2001)
Toxicol. Sci
, vol.59
, pp. 169-177
-
-
Enomoto, A.1
Itoh, K.2
Nagayoshi, E.3
Haruta, J.4
Kimura, T.5
O'Connor, T.6
Harada, T.7
Yamamoto, M.8
-
15
-
-
0013909028
-
Spectrophotometric assay of the liver enzyme that catalyzes sulfobromophthalein-glutathione conjugation
-
Goldstein, J., and Combes, B. (1966). Spectrophotometric assay of the liver enzyme that catalyzes sulfobromophthalein-glutathione conjugation. J. Lab. Clin. Med. 67, 863-872.
-
(1966)
J. Lab. Clin. Med
, vol.67
, pp. 863-872
-
-
Goldstein, J.1
Combes, B.2
-
16
-
-
0020081385
-
Role of ligandin as a binding protein and as an enzyme in the biliary excretion of sulfobromophthalein
-
Gregus, Z., and Klaassen, C. D. (1982). Role of ligandin as a binding protein and as an enzyme in the biliary excretion of sulfobromophthalein. J. Pharmacol. Exp. Ther. 221, 242-246.
-
(1982)
J. Pharmacol. Exp. Ther
, vol.221
, pp. 242-246
-
-
Gregus, Z.1
Klaassen, C.D.2
-
17
-
-
0004636223
-
Identification of metabolites of sulfobromophthalein
-
Grodsky, G. M., Carbone, J. V., and Fanska, R. (1959). Identification of metabolites of sulfobromophthalein. J. Clin. Invest. 38, 1981-1988.
-
(1959)
J. Clin. Invest
, vol.38
, pp. 1981-1988
-
-
Grodsky, G.M.1
Carbone, J.V.2
Fanska, R.3
-
18
-
-
0033967866
-
Molecular cloning and functional characterization of the mouse organic-anion-transporting polypeptide 1 (Oatp1) and mapping of the gene to chromosome X
-
Hagenbuch, B., Adler, I. D., and Schmid, T. E. (2000). Molecular cloning and functional characterization of the mouse organic-anion-transporting polypeptide 1 (Oatp1) and mapping of the gene to chromosome X. Biochem. J. 345(Pt 1), 115-120.
-
(2000)
Biochem. J
, vol.345
, Issue.PART 1
, pp. 115-120
-
-
Hagenbuch, B.1
Adler, I.D.2
Schmid, T.E.3
-
19
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh, K., Chiba, T., Takahashi, S., Ishii, T., Igarashi, K., Katoh, Y., Oyake, T., Hayashi, N., Satoh, K., Hatayama, I., et al. (1997). An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun. 236, 313-322.
-
(1997)
Biochem. Biophys. Res. Commun
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
Satoh, K.9
Hatayama, I.10
-
20
-
-
0344733048
-
Phenol 3, 6 dibromphthalein disulfonate, a new compound For the study of liver disease
-
Javitt, N. B. (1964). Phenol 3, 6 dibromphthalein disulfonate, a new compound For the study of liver disease. Proc. Soc. Exp. Biol. Med. 117, 254-257.
-
(1964)
Proc. Soc. Exp. Biol. Med
, vol.117
, pp. 254-257
-
-
Javitt, N.B.1
-
21
-
-
0036535488
-
Role of rat multidrug resistance protein 2 in plasma and biliary disposition of dibromosulfophthalein after microsomal enzyme induction
-
Johnson, D. R., and Klaassen, C. D. (2002). Role of rat multidrug resistance protein 2 in plasma and biliary disposition of dibromosulfophthalein after microsomal enzyme induction. Toxicol. Appl. Pharmacol. 180, 56-63.
-
(2002)
Toxicol. Appl. Pharmacol
, vol.180
, pp. 56-63
-
-
Johnson, D.R.1
Klaassen, C.D.2
-
22
-
-
0029876334
-
Transient expression of oatp organic anion transporter in mammalian cells: Identification of candidate substrates
-
Kanai, N., Lu, R., Bao, Y., Wolkoff, A. W., and Schuster, V. L. (1996). Transient expression of oatp organic anion transporter in mammalian cells: Identification of candidate substrates. Am. J. Physiol. 270, F319-325.
-
(1996)
Am. J. Physiol
, vol.270
-
-
Kanai, N.1
Lu, R.2
Bao, Y.3
Wolkoff, A.W.4
Schuster, V.L.5
-
23
-
-
0014147984
-
Species variation in metabolism, storage, and excretion of sulfobromophthalein
-
Klaassen, C. D., and Plaa, G. L. (1967). Species variation in metabolism, storage, and excretion of sulfobromophthalein. Am. J. Physiol. 213, 1322-1326.
-
(1967)
Am. J. Physiol
, vol.213
, pp. 1322-1326
-
-
Klaassen, C.D.1
Plaa, G.L.2
-
24
-
-
0842304134
-
Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tertbutylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult
-
Kraft, A. D., Johnson, D. A., and Johnson, J. A. (2004). Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tertbutylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult. J. Neurosci. 24, 1101-1112.
-
(2004)
J. Neurosci
, vol.24
, pp. 1101-1112
-
-
Kraft, A.D.1
Johnson, D.A.2
Johnson, J.A.3
-
25
-
-
65549087088
-
Metabolism of sulfobromophthalein sodium (BSP) in the rat
-
Krebs, J. S., and Brauer, R. W. (1958). Metabolism of sulfobromophthalein sodium (BSP) in the rat. Am. J. Physiol. 194, 37-43.
-
(1958)
Am. J. Physiol
, vol.194
, pp. 37-43
-
-
Krebs, J.S.1
Brauer, R.W.2
-
26
-
-
36349015332
-
Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway
-
Maher, J. M., Dieter, M. Z., Aleksunes, L. M., Slitt, A. L., Guo, G., Tanaka, Y., Scheffer, G. L., Chan, J. Y., Manautou, J. E., Chen, Y., et al. (2007). Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway. Hepatology 46, 1597-1610.
-
(2007)
Hepatology
, vol.46
, pp. 1597-1610
-
-
Maher, J.M.1
Dieter, M.Z.2
Aleksunes, L.M.3
Slitt, A.L.4
Guo, G.5
Tanaka, Y.6
Scheffer, G.L.7
Chan, J.Y.8
Manautou, J.E.9
Chen, Y.10
-
27
-
-
57349108021
-
Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice
-
Okada, K., Shoda, J., Taguchi, K., Maher, J. M., Ishizaki, K., Inoue, Y., Ohtsuki, M., Goto, N., Takeda, K., Utsunomiya, H., et al. (2008). Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice. Am. J. Physiol. Gastrointest. Liver Physiol. 295, G735-G747.
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.295
-
-
Okada, K.1
Shoda, J.2
Taguchi, K.3
Maher, J.M.4
Ishizaki, K.5
Inoue, Y.6
Ohtsuki, M.7
Goto, N.8
Takeda, K.9
Utsunomiya, H.10
-
28
-
-
0035853157
-
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
-
Ramos-Gomez, M., Kwak, M. K., Dolan, P. M., Itoh, K., Yamamoto, M., Talalay, P., and Kensler, T. W. (2001). Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 98, 3410-3415.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A
, vol.98
, pp. 3410-3415
-
-
Ramos-Gomez, M.1
Kwak, M.K.2
Dolan, P.M.3
Itoh, K.4
Yamamoto, M.5
Talalay, P.6
Kensler, T.W.7
-
29
-
-
61349117533
-
Increased Nrf2 Activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species
-
Reisman, S. A., Yeager, R. L., Yamamoto, M., and Klaassen, C. D. (2009). Increased Nrf2 Activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species. Toxicol. Sci. 108 35-47.
-
(2009)
Toxicol. Sci
, vol.108
, pp. 35-47
-
-
Reisman, S.A.1
Yeager, R.L.2
Yamamoto, M.3
Klaassen, C.D.4
-
30
-
-
0042858530
-
Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites
-
Slitt, A. L., Cherrington, N. J., Maher, J. M., and Klaassen, C. D. (2003). Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites. Drug Metab. Dispos. 31, 1176-1186.
-
(2003)
Drug Metab. Dispos
, vol.31
, pp. 1176-1186
-
-
Slitt, A.L.1
Cherrington, N.J.2
Maher, J.M.3
Klaassen, C.D.4
-
31
-
-
0036570346
-
Glutamate-cysteine ligase modifier subunit: Mouse Gclm gene structure and regulation by agents that cause oxidative stress
-
Solis, W. A., Dalton, T. P., Dieter, M. Z., Freshwater, S., Harrer, J. M., He, L., Shertzer, H. G., and Nebert, D. W. (2002). Glutamate-cysteine ligase modifier subunit: Mouse Gclm gene structure and regulation by agents that cause oxidative stress. Biochem. Pharmacol. 63, 1739-1754.
-
(2002)
Biochem. Pharmacol
, vol.63
, pp. 1739-1754
-
-
Solis, W.A.1
Dalton, T.P.2
Dieter, M.Z.3
Freshwater, S.4
Harrer, J.M.5
He, L.6
Shertzer, H.G.7
Nebert, D.W.8
-
32
-
-
0021918821
-
Inhibitors for distinction of three types of human glutathione transferase
-
Tahir, M. K., Guthenberg, C., and Mannervik, B. (1985). Inhibitors for distinction of three types of human glutathione transferase. FEBS Lett. 181, 249-252.
-
(1985)
FEBS Lett
, vol.181
, pp. 249-252
-
-
Tahir, M.K.1
Guthenberg, C.2
Mannervik, B.3
-
33
-
-
0037626452
-
Biliary excretion of phenolphthalein sulfate in rats
-
Tanaka, H., Sano, N., and Takikawa, H. (2003). Biliary excretion of phenolphthalein sulfate in rats. Pharmacology 68, 177-182.
-
(2003)
Pharmacology
, vol.68
, pp. 177-182
-
-
Tanaka, H.1
Sano, N.2
Takikawa, H.3
-
34
-
-
33750613056
-
Two-site substrate recognition model for the Keap1-Nrf2 system: A hinge and latch mechanism
-
Tong, K. I., Kobayashi, A., Katsuoka, F., and Yamamoto, M. (2006). Two-site substrate recognition model for the Keap1-Nrf2 system: A hinge and latch mechanism. Biol. Chem. 387, 1311-1320.
-
(2006)
Biol. Chem
, vol.387
, pp. 1311-1320
-
-
Tong, K.I.1
Kobayashi, A.2
Katsuoka, F.3
Yamamoto, M.4
-
35
-
-
0037136037
-
Functional characterization of the mouse organicanion-transporting polypeptide 2
-
van Montfoort, J. E., Schmid, T. E., Adler, I. D., Meier, P. J., and Hagenbuch, B. (2002). Functional characterization of the mouse organicanion-transporting polypeptide 2. Biochim. Biophys. Acta. 1564, 183-188.
-
(2002)
Biochim. Biophys. Acta
, vol.1564
, pp. 183-188
-
-
van Montfoort, J.E.1
Schmid, T.E.2
Adler, I.D.3
Meier, P.J.4
Hagenbuch, B.5
-
36
-
-
0021114956
-
A set of inhibitors for discrimination between the basic isozymes of glutathione transferase in rat liver
-
Yalcin, S., Jensson, H., and Mannervik, B. (1983). A set of inhibitors for discrimination between the basic isozymes of glutathione transferase in rat liver. Biochem. Biophys. Res. Commun. 114, 829-834.
-
(1983)
Biochem. Biophys. Res. Commun
, vol.114
, pp. 829-834
-
-
Yalcin, S.1
Jensson, H.2
Mannervik, B.3
|