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Volumn 77, Issue 1, 2009, Pages 217-225

Synthetic studies towards the identification of novel capuramycin analogs with mycobactericidal activity

Author keywords

Acid and Base Stable Protecting Group; Antimycobactericidal Activity; Capuramycin; Capuramycin Analog Synthesis; MraY inhibitor

Indexed keywords


EID: 65549139464     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-08-S(F)38     Document Type: Article
Times cited : (8)

References (42)
  • 2
    • 19744367767 scopus 로고    scopus 로고
    • Cohen J. Science 306 (2004) 1872
    • (2004) Science , vol.306 , pp. 1872
    • Cohen, J.1
  • 22
    • 65549106594 scopus 로고    scopus 로고
    • unpublished data
    • M. Kurosu and K. Li, unpublished data.
    • Kurosu, M.1    Li, K.2
  • 37
    • 65549141344 scopus 로고    scopus 로고
    • note
    • Because 13b was isolated exclusively in the conversion of 12 to 13b it was concluded that the C3-TBS silyl group did not migrate to the C2-position. Thus, no rapid equivilation of the silyl group was taking place.
  • 38
    • 65549149239 scopus 로고    scopus 로고
    • note
    • We have not observed separation of the diastereomers caused by rac-10 throughout the syntheses of 21 and 22.
  • 40
    • 65549100278 scopus 로고    scopus 로고
    • note
    • Trace amounts of the desired coupling product were isolated with the pivaloyl-or benzoyl-protected imidate of D-manno-pyranuronate.
  • 41
    • 65549165596 scopus 로고    scopus 로고
    • note
    • 3 in MeOH (for 12 h) to regenerate 10 in quantitative yield.
  • 42
    • 65549088153 scopus 로고    scopus 로고
    • note
    • +: 549.1809; found: 549.1815.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.