Lipoxin A4 and serum amyloid a differentially modulate phospholipase D in human fibroblast-like synoviocytes

European Journal of Inflammation

Volumn 7, Issue 1, 2009, Pages 9-17

  Sodin Semrl, S ^a   Antico, G ^b   Mikus, R ^c   Lakota, K ^a   Varga, J ^b   Fiore, S ^d  

^a UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

^b NORTHWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d GENENTECH INC   (United States)

Author keywords

Inflammation; Lipid mediators; Lipoxin; Phosphatidic acid; Signal transduction

Indexed keywords

FORMYLPEPTIDE RECEPTOR LIKE 1; INTERLEUKIN 1BETA; INTERLEUKIN 8; LIPOXIN A; PHOSPHATIDIC ACID; PHOSPHOLIPASE D; SERUM AMYLOID A;

ARTHRITIS; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; RECEPTOR BINDING; SYNOVIOCYTE;

EID: 65549126867     PISSN: 1721727X     EISSN: None     Source Type: Journal    
DOI: 10.1177/1721727x0900700102     Document Type: Article

References (39)

1. Isomaki P, Punnonen J. Pro- and anti-inflammatory cytokines in rheumatoid arthritis. Ann Med 1997; 29: 499-507.
2. Serhan CN. Resolution phases of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways. Annu Rev Immunol 2007; 25:101-37.
3. Gewirtz AT, Neish AS, Madara JL. Mechanisms of active intestinal inflammation and potential down-regulation via lipoxins. Adv Exp Med Biol 2002; 507:229-36.
4. Bonnans C, Vachier I, Chavis C, Godard P, Bousquet J, Chanez P. Lipoxins are potential endogenous anti-inflammatory mediators in asthma. Am J Respir Crit Care Med 2002; 165:1531-5.
5. Serhan CN, Levy BD, Clish CB, Gronert K, Chiang N. Lipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity. Ernst Schering Res Found Workshop 2000; 31:143-85.
6. Sodin-Semrl S, Spagnolo A, Barbara B, Varga J, Fiore S. Lipoxin A4 counteracts synergistic activation of human fibroblast-like synoviocytes. Int J Immunopathol Pharmacol 2004; 17:15-25.
7. Takano T, Fiore S, Maddox JF, Brady HR, Petasis NA, Serhan CN. Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: Evidence for anti-inflammatory receptors. J Exp Med 1997; 185:1693-1704.
8. Sodin-Semrl S, Taddeo B, Tseng D, Varga J, Fiore S. Lipoxin A4 inhibits IL-1 beta-induced IL-6, IL-8, and matrix metalloproteinase-3 production in human synovial fibroblasts and enhances synthesis of tissue inhibitors of metalloproteinases. J Immunol 2000; 164:2660-6.
9. Fiore S, Sodin-Semrl S, Kang Y, Varga J. Activation of LXA4R by LXA4 or serum amyloid A results in opposite regulation of NF-κB DNA binding in human synovial fibroblasts. Arthritis Rheum 2000; 43:S158.
10. Su SB, Gong W, Gao JL, Shen W, Murphy PM, Oppenheim JJ, Wang JM. A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells. J Exp Med 1999; 189:395-402.
11. Vallon R, Freuler F, Desta-Tsedu N, et al. Serum amyloid A (apoSAA) expression is up-regulated in rheumatoid arthritis and induces transcription of matrix metalloproteinases. J Immunol 2001; 166: 2801-7.
12. Patel H, Fellowes R, Coade S, Woo P. Human serum amyloid A has cytokine-like properties. Scan J Immunol 1998; 48:410-8.
13. Sodin-Semrl S, Spagnolo A, Mikus R, Barbaro B, Varga J, Fiore S. Opposing regulation of interleukin-8 and NF-kappaB responses by lipoxin A4 and serum amyloid A via the common lipoxin A receptor. Int J Immunopathol Pharmacol 2004; 17:145-56.
14. O'Hara R, Murphy EP, Whitehead AS, FitzGerald O, Breshihan B. Local expression of the serum amyloid A and formyl peptide receptor-like 1 genes in synovial tissue is associated with matrix metalloproteinase production in patients with inflammatory arthritis. Arthritis Rheum 2004; 50:1788-99.
15. He RL, Zhou J, Hanson CZ, Chen J, Cheng N, Ye RD. Serum amyloid A induces G-CSF expression and neutrophilia via Toll-like receptor 2. Blood 2009; 113:429-37.
16. Fiore S, Romano M, Reardon EM, Serhan CN. Induction of functional lipoxin A4 receptors in HL-60 cells. Blood 1993; 81:3395-3403.
17. Exton JH. Regulation of phospholipase D. FEBS Lett 2002; 531:58-61.
18. Powner DJ, Wakelam MJ. The regulation of phospholipase D by inositol phospholipids and small GTPases. FEBS Lett 2002; 531:62-4.
19. Cummings R, Parinandi N, Wang L, Usatyuk P, Natarajan V. Phospholipase D/ phosphatidic acid signal transduction: role and physiological significance in lung. Mol Cell Biochem 2002; 234: 99-109.
20. Kishikawa K, Chalfant CE, Perry DK, Bielawska A, Hannun YA. Phosphatidic acid is a potent and selective inhibitor of protein phosphatase 1 and an inhibitor of ceramide-mediated responses. J Biol Chem 1999; 274:21335-41.
21. Goldberg Y. Protein phosphatase 2A: who shall regulate the regulator? Biochem Pharmacol 1999; 57:321-8.
22. DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M. A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature 1997; 388:548-54.
23. Sipe J. Revised nomenclature for serum amyloid A (SAA). Nomenclature Committee of the International Society of Amyloidosis. Part 2. Amyloid 1999; 6:67-70.
24. Croft D, McIntyre P, Wibulswas A, Kramer I. Sustained elevated levels of VCAM-1 in cultured fibroblast-like synoviocytes can be achieved by TNF-α in combination with either IL-4 or IL-13 through increased mRNA stability. Am J Pathol 1999; 154:1149-58.
25. Kang Y, Sodin-Semrl S, Varai G, Varga J, Taddeo B, Fiore S. Impact of selected serine, threonine and tyrosine mutations in the intracellular domains of the human lipoxin A4 receptor on desensitization and signaling. Arthritis Rheum 2000; 42:S191.
26. Kang Y, Taddeo B, Varai G, Varga J, Fiore S. Mutations of serine 236-237 and tyrosine 302 residues in the human lipoxin A4 receptor intracellular domains result in sustained signaling. Biochem 2000; 39: 13551-7.
27. Jung YD, Fan F, McConkey DJ, et al. Role of P38 MAPK, AP-1, and NF-kappaB in interleukin-1 beta-induced IL-8 expression in human vascular smooth muscle cells. Cytokine 2002; 18:206-13.
28. Chiang N, Fierro IM, Gronert K, Serhan CN. Activation of lipoxin A(4) receptors by aspirin-triggered lipoxins and select peptidies evokes ligand-specific responses in inflammation. J Exp Med 2000; 191:1197-1208.
29. Stenkamp RE, Teller DC, Palczewski K. Crystal structure of rhodopsin: a G-protein-coupled receptor. Chem Biochem 2002; 3:963-7.
30. Fiore S, Ryeom SW, Weller PF, Serhan CN. Lipoxin recognition sites. Specific binding of labeled lipoxin A4 with human neutrophils. J Biol Chem 1992; 267: 16168-76.
31. He R, Sang H, Ye RD. Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R. Blood 2003; 101:1572-81.
32. Ueno N, Murakami M, Kudo I. Functional crosstalk between phospholipase D(2) and signaling phospholipase A(2)/cyclooxygenase-2-mediated prostaglandin biosynthetic pathways. FEBS Lett 2000; 475:242-6.
33. Kiel D, Feinmark SJ. Phospholipase D activity regulates the binding of leukotriene B4 to human polymorphonuclear leukocytes. J Pharmacol Exp Ther 1996; 278:645-53.
34. Steed PM, Chow AH. Intracellular signaling by phospholipase D as a therapeutic target. Curr Pharm Biotechnol 2001; 2:241-56.
35. Jenkins GM, Frohman MA. Phospholipase D: a lipid centric review. Cell Mol Life Sci 2005; 62:2305-16.
36. Natarajan V, Jayaram HN, Scribner WM, Garcia JG. Activation of endothelial cell phospholipase D by sphingosine and sphingosine-1-phosphate. Am J Respir Cell Mol Biol 1994; 11:221-9.
37. Maderna P, Cottell DC, Berlasconi G, Petasis NA, Brady HR, Godson C. Lipoxins induce actin reorganization in monocytes and macrophages but not in neutrophils: differential involvement of rho GTPases. Am J Pathol 2002; 160:2275-83.
38. Exton JH. Phospholipase D-structure, regulation and function. Rev Physiol Biochem Pharmacol 2002; 144:1-94.
39. Sonoda Y, Kasahara T, Yamaguchi Y, Kuno K, Matsushima K, Mukaida N. Stimulation of interleukin-8 production by okadaic acid and vanadate in a human promyelocyte cell line, an HL-60 subline. Possible role of mitogen-activated protein kinase on the okadaic acid-induced NF-kappaB activation. J Biol Chem 1997; 272:15366-72.