Incorporation of 5-chlorocytosine into mammalian DNA results in heritable gene silencing and altered cytosine methylation patterns

Carcinogenesis

Volumn 30, Issue 5, 2009, Pages 886-893

  Lao, Victoria Valinluck ^a,b   Herring, Jason L ^a   Kim, Cherine H ^a   Darwanto, Agus ^a   Soto, Ubaldo ^a   Sowers, Lawrence C ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; 5 CHLOROCYTOSINE; 5 METHYLCYTOSINE; 5 METHYLDEOXYCYTIDINE; 5' CHLORO 2' DEOXYCYTIDINE 5' TRIPHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; METHYL 2' DEOXYCYTIDINE 5' TRIPHOSPHATE; PYRIMIDINE NUCLEOSIDE; TIOGUANINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CHO CELL; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; GENE EXPRESSION; GENE SILENCING; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PYROSEQUENCING;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; CYTOSINE; DNA; DNA DAMAGE; DNA REPLICATION; GENE SILENCING; GLYCINE; HUMANS; INFLAMMATION; MAMMALS; METHYLATION; NEOPLASMS; OLIGONUCLEOTIDES;

EID: 65549089202     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgp060     Document Type: Article

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