Activation of mitogen-activated protein kinases in gerbil hippocampus with ischemic tolerance induced by 3-nitropropionic acid

Neuroscience Letters

Volumn 278, Issue 1-2, 2000, Pages 101-104

  Sugino, Toshiyuki ^a   Nozaki, Kazuhiko ^a   Hashimoto, Nobuo ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

3 Nitropropionic acid; c Jun NH2 terminal kinases; Extracellular signal regulated kinases; Hippocampus; Ischemic tolerance; p38 mitogen activated protein kinases; Transient global ischemia

Indexed keywords

3 NITROPROPIONIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; ENZYME ACTIVATION; GERBIL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BRAIN ISCHEMIA; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME INHIBITORS; GERBILLINAE; HIPPOCAMPUS; IMMUNOENZYME TECHNIQUES; ISCHEMIC PRECONDITIONING; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE TISSUE PROTEINS; NITRO COMPOUNDS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROPIONIC ACIDS;

EID: 0033987107     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00906-4     Document Type: Article

References (16)

1. ATP channels and actin cytoskeleton. Am. J. Physiol. 276:1999;H1361-H1368.
2. Coles C.J., Edmondson D.E., Singer T.P. Inactivation of succinate dehydrogenase by 3-nitropropionate. J. Biol. Chem. 254:1979;5161-5167.
3. Davis R.J. Signal transduction by the c-Jun N-terminal kinase. Biochem. Soc. Symp. 64:1999;1-12.
4. Haq S.E.A., Clerk A., Sugden P.H. Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by adenosine in the perfused rat heart. FEBS Lett. 434:1998;305-308.
5. Herdegen T., Claret F.-X., Kallunki T., Martin-Villalba A., Winter C., Hunter T., Karin M. Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury. J. Neurosci. 18:1998;5124-5135.
6. Kitagawa K., Matsumoto M., Tagaya M., Hata R., Ueda H., Niinobe M., Handa N., Fukunaga R., Kimura K., Mikoshiba K., Kamada T. 'Ischemic tolerance' phenomenon found in the brain. Brain Res. 528:1990;21-24.
7. Kyriakis J.M., Avruch J. Protein kinase cascades activated by stress and inflammatory cytokines. Bioessays. 18:1996;567-577.
8. Maroney A.C., Glicksman M.A., Basma A.N., Walton K.M., Ernest K. Jr, Murphy C.A., Bartlett B.A., Finn J.P., Angeles T., Matsuda Y., Neff N.T., Dionne C.A. Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway. J. Neurosci. 18:1998;104-111.
9. Maulik N., Watanabe M., Zu Y.L., Huang C.K., Cordis G.A., Schley J.A., Das D.K. Ischemic preconditioning triggers the activation of MAP kinases and MAPKAP kinase 2 in rat hearts. FEBS Lett. 396:1996;233-237.
10. Nagarkatti D.S., Sha'afi R.I. Role of p38 MAP kinase in myocardial stress. J. Mol. Cell. Cardiol. 30:1998;1651-1664.
11. Shamloo M., Rytter A., Wieloch T. Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning. Neuroscience. 93:1999;81-88.
12. Sugino T., Nozaki K., Tokime T., Hashimoto N., Kikuchi H. 3-Nitropropionic acid induces poly(ADP-ribosyl)ation and apoptosis related gene expression in the striatum in vivo. Neurosci. Lett. 237:1997;121-124.
13. Sugino T., Nozaki K., Takagi Y., Hashimoto N. 3-Nitropropionic acid induces ischemic tolerance in gerbil hippocampus in vivo. Neurosci. Lett. 259:1999;9-12.
14. Tauskela J.S., Chakravarthy B.R., Murray C.L., Wang Y., Comas T., Hogan M., Hakim A., Morley P. Evidence from cultured rat cortical neurons of differences in the mechanism of ischemic preconditioning of brain and heart. Brain Res. 827:1999;143-151.
15. MAPK in microglia after ischemia. J. Neurochem. 70:1998;1764-1767.
16. Weinbrenner C., Liu G.-S., Cohen M.V., Downey J.M. Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart. J. Mol. Cell. Cardiol. 29:1997;2383-2391.