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Volumn 10, Issue 5, 2000, Pages 389-395

Evidence for the involvement of the hippocampus in the pathophysiology of schizophrenia

Author keywords

Gene expression; Hippocampus; Neuroanatomy; Pathophysiology; Schizophrenia

Indexed keywords

ARTICLE; BRAIN SIZE; CYTOARCHITECTURE; GENE EXPRESSION; HIPPOCAMPUS; HISTOPATHOLOGY; HUMAN; LIMBIC SYSTEM; MOLECULAR BIOLOGY; NERVE CELL DIFFERENTIATION; NEUROPSYCHOLOGY; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SCHIZOPHRENIA;

EID: 0033843278     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-977X(00)00097-3     Document Type: Article
Times cited : (66)

References (65)
  • 1
    • 0026011733 scopus 로고
    • Counterpoint: A sensory gating-hippocampal model of schizophrenia
    • Adler L.E., Waldo M.C. Counterpoint: A sensory gating-hippocampal model of schizophrenia. Schiz. Bull. 17:1991;19-23.
    • (1991) Schiz. Bull. , vol.17 , pp. 19-23
    • Adler, L.E.1    Waldo, M.C.2
  • 2
    • 0025915446 scopus 로고
    • Some cytoarchitectonic disturbances of the entorhinal cortex in schizophrenia
    • Arnold S.E., Hyman B.T., van Hesen G.W., Damasio A.R. Some cytoarchitectonic disturbances of the entorhinal cortex in schizophrenia. Arch. Gen. Psychiatry. 48:1991;625-632.
    • (1991) Arch. Gen. Psychiatry , vol.48 , pp. 625-632
    • Arnold, S.E.1    Hyman, B.T.2    Van Hesen, G.W.3    Damasio, A.R.4
  • 5
    • 0029825402 scopus 로고    scopus 로고
    • Neonatal insult to the hppocampal region and schizophrenia: A review and a putative model
    • Beauregard M., Bachevalier J. Neonatal insult to the hppocampal region and schizophrenia: a review and a putative model. Can. J. Psychiatry. 41:1996;446-456.
    • (1996) Can. J. Psychiatry , vol.41 , pp. 446-456
    • Beauregard, M.1    Bachevalier, J.2
  • 6
    • 0032527572 scopus 로고    scopus 로고
    • A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives
    • Benes F.M., Kwok E.W., Vincent S.L., Todtenkopf M.S. A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives. Biol. Psychiatry. 44:1998;88-97.
    • (1998) Biol. Psychiatry , vol.44 , pp. 88-97
    • Benes, F.M.1    Kwok, E.W.2    Vincent, S.L.3    Todtenkopf, M.S.4
  • 7
    • 0032079453 scopus 로고    scopus 로고
    • Regionally specific neuronal pathology in untreated patients with schizophrenia: A proton magnetic resonance spectroscopic imaging study
    • Bertolino A., Callicott J.H., Elman I., Mattay V.S., Tedesci G., Frank J.A., Breier A., Weinberger D.R. Regionally specific neuronal pathology in untreated patients with schizophrenia: a proton magnetic resonance spectroscopic imaging study. Biol. Psychiatry. 43:1998;641-648.
    • (1998) Biol. Psychiatry , vol.43 , pp. 641-648
    • Bertolino, A.1    Callicott, J.H.2    Elman, I.3    Mattay, V.S.4    Tedesci, G.5    Frank, J.A.6    Breier, A.7    Weinberger, D.R.8
  • 8
    • 0025293654 scopus 로고
    • Reduced temporal limbic structure volumes on magnetic resonance images in first episode schizophrenia
    • Bogerts B., Ashtari M., Degreef G., Alvir J.M., Bilder R.M., Lieberman J.A. Reduced temporal limbic structure volumes on magnetic resonance images in first episode schizophrenia. Psychiatry Res. 35:1990;1-13.
    • (1990) Psychiatry Res. , vol.35 , pp. 1-13
    • Bogerts, B.1    Ashtari, M.2    Degreef, G.3    Alvir, J.M.4    Bilder, R.M.5    Lieberman, J.A.6
  • 9
    • 0027283411 scopus 로고
    • Recent advances in the neuropathology of schizophrenia
    • Bogerts B. Recent advances in the neuropathology of schizophrenia. Schizoph. Bull. 19:1993;431-445.
    • (1993) Schizoph. Bull. , vol.19 , pp. 431-445
    • Bogerts, B.1
  • 10
    • 0025946146 scopus 로고
    • Carbachol infusion into the dentate gyrus disrupts sensorimotor gating of the startle reflex in rats
    • Caine S.B., geyer M.A., Swerdlow N.R. Carbachol infusion into the dentate gyrus disrupts sensorimotor gating of the startle reflex in rats. Psychopharmacology. 105:1991;347-354.
    • (1991) Psychopharmacology , vol.105 , pp. 347-354
    • Caine, S.B.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 11
    • 0030561083 scopus 로고    scopus 로고
    • Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia
    • Chambers R.A., Moore J., McEvoy J.P., Levin E.D. Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia. Neuropschopharmacology. 15:1996;587-594.
    • (1996) Neuropschopharmacology , vol.15 , pp. 587-594
    • Chambers, R.A.1    Moore, J.2    McEvoy, J.P.3    Levin, E.D.4
  • 12
    • 0025949451 scopus 로고
    • Decrease hippocampal expression of a glutamate receptor gene in schizophrenia
    • Collinge J., Curtis D. Decrease hippocampal expression of a glutamate receptor gene in schizophrenia. Br. J. Psychiatry. 159:1991;857-859.
    • (1991) Br. J. Psychiatry , vol.159 , pp. 857-859
    • Collinge, J.1    Curtis, D.2
  • 15
    • 0026070134 scopus 로고
    • Dopamine in schizophrenia: A review and reconceptualization
    • Davis K.L., Kahn R.S., Ko G., Davidson M. Dopamine in schizophrenia: a review and reconceptualization. Am. J. Psychiatry. 148:1991;1474-1486.
    • (1991) Am. J. Psychiatry , vol.148 , pp. 1474-1486
    • Davis, K.L.1    Kahn, R.S.2    Ko, G.3    Davidson, M.4
  • 18
    • 0030798020 scopus 로고    scopus 로고
    • Schizophrenia as a chronic active brain process: A study of progressive brain structural change subsequent to the onset of schizophrenia
    • DeLisi L.E., Sakuma M., Tew W., Kushner M., Hoff A.L., Grimson R. Schizophrenia as a chronic active brain process: a study of progressive brain structural change subsequent to the onset of schizophrenia. Psychiatry Res. Neuroimag. 74:1997;129-140.
    • (1997) Psychiatry Res. Neuroimag. , vol.74 , pp. 129-140
    • Delisi, L.E.1    Sakuma, M.2    Tew, W.3    Kushner, M.4    Hoff, A.L.5    Grimson, R.6
  • 19
    • 0032053871 scopus 로고    scopus 로고
    • Hippocampal neuronal dysfunction in schizophrenia as measured by proton magnetic resonance spectroscopy
    • Deicken R.F., Zhou L., Schuff N., Fein G., Weiner M.W. Hippocampal neuronal dysfunction in schizophrenia as measured by proton magnetic resonance spectroscopy. Biol. Psychiatry. 43:1998;483-488.
    • (1998) Biol. Psychiatry , vol.43 , pp. 483-488
    • Deicken, R.F.1    Zhou, L.2    Schuff, N.3    Fein, G.4    Weiner, M.W.5
  • 20
    • 0033594897 scopus 로고    scopus 로고
    • Reduced Hippocampal N-Acetylaspartate without volume loss in schizophrenia
    • Deicken R.F., Pegues M., Amend D. Reduced Hippocampal N-Acetylaspartate without volume loss in schizophrenia. Schizophr. Res. 37:1999;217-223.
    • (1999) Schizophr. Res. , vol.37 , pp. 217-223
    • Deicken, R.F.1    Pegues, M.2    Amend, D.3
  • 21
    • 0030882138 scopus 로고    scopus 로고
    • Postmortem studies of the hippocampal formation in schizophrenia
    • Dwork A.J. Postmortem studies of the hippocampal formation in schizophrenia. Schizophr. Bull. 23:1997;385-402.
    • (1997) Schizophr. Bull. , vol.23 , pp. 385-402
    • Dwork, A.J.1
  • 22
    • 0028965594 scopus 로고
    • Altered synaptophysin expression as a marker of synaptic pathology in schizophrenia
    • Eastwood S.L., Burnet P.W., Harrison P.J. Altered synaptophysin expression as a marker of synaptic pathology in schizophrenia. Neuroscience. 66:1995;309-319.
    • (1995) Neuroscience , vol.66 , pp. 309-319
    • Eastwood, S.L.1    Burnet, P.W.2    Harrison, P.J.3
  • 23
    • 0028907468 scopus 로고
    • Decreased expression of mRNAs encoding non-NMDA glutamate receptors GluR1 and GluR2 in medial temporal lobe neurons in schizophrenia
    • Eastwood S.L., McDonald B., Burnet P.W., Beckwith J.P., Kerwin R.W., Harrison P.J. Decreased expression of mRNAs encoding non-NMDA glutamate receptors GluR1 and GluR2 in medial temporal lobe neurons in schizophrenia. P.J. Brain Res. Mol. Brain Res. 29:1995;211-223.
    • (1995) P.J. Brain Res. Mol. Brain Res. , vol.29 , pp. 211-223
    • Eastwood, S.L.1    McDonald, B.2    Burnet, P.W.3    Beckwith, J.P.4    Kerwin, R.W.5    Harrison, P.J.6
  • 24
    • 0032101622 scopus 로고    scopus 로고
    • Hippocampal and cortical growth-associated protein-43 messenger RNA in schizophrenia
    • Eastwood S.L., Harrison P.J. Hippocampal and cortical growth-associated protein-43 messenger RNA in schizophrenia. Neuroscience. 86:1998;437-448.
    • (1998) Neuroscience , vol.86 , pp. 437-448
    • Eastwood, S.L.1    Harrison, P.J.2
  • 26
    • 0029085870 scopus 로고
    • Evidence in postmortem brain tissue for decreased numbers of hippcampal nicotinic receptors in schizophrenia
    • Freedman R., Hall M., Adler L.E., Leonard S. Evidence in postmortem brain tissue for decreased numbers of hippcampal nicotinic receptors in schizophrenia. Biol. Psychiatry. 38:1995;22-33.
    • (1995) Biol. Psychiatry , vol.38 , pp. 22-33
    • Freedman, R.1    Hall, M.2    Adler, L.E.3    Leonard, S.4
  • 30
    • 0028278952 scopus 로고
    • Relations between neuropsychological performance and brain morphological and physiological measures in monozygotic twins discordant for schizophrenia
    • Goldberg T.E., Torrey E.F., Berman K.F., Weinberger D.R. Relations between neuropsychological performance and brain morphological and physiological measures in monozygotic twins discordant for schizophrenia. Psychiatry Res. 55:1994;51-61.
    • (1994) Psychiatry Res. , vol.55 , pp. 51-61
    • Goldberg, T.E.1    Torrey, E.F.2    Berman, K.F.3    Weinberger, D.R.4
  • 33
    • 0031903740 scopus 로고    scopus 로고
    • Neurocognitive deficit in schizophrenia: A quantitative review of the evidence
    • Heinrichs R.W., Zakzanis K.K. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology. 12:1998;426-445.
    • (1998) Neuropsychology , vol.12 , pp. 426-445
    • Heinrichs, R.W.1    Zakzanis, K.K.2
  • 36
    • 0024439480 scopus 로고
    • Hippocampal pathologic findings in schizophrenia: A morphometric study
    • Jeste D.V., Lohr J.B. Hippocampal pathologic findings in schizophrenia: a morphometric study. Arch. Gen. Psychiatry. 46:1989;1019-1024.
    • (1989) Arch. Gen. Psychiatry , vol.46 , pp. 1019-1024
    • Jeste, D.V.1    Lohr, J.B.2
  • 38
    • 0028886663 scopus 로고
    • Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine
    • Lipska B.K., Swerdlow N.R., Geyer M.A., Jaskiw G.E., Braff D.L., Weinberger D.R. Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine. Psychopharmacology. 122:1995;35-43.
    • (1995) Psychopharmacology , vol.122 , pp. 35-43
    • Lipska, B.K.1    Swerdlow, N.R.2    Geyer, M.A.3    Jaskiw, G.E.4    Braff, D.L.5    Weinberger, D.R.6
  • 39
    • 0028868860 scopus 로고
    • Proton magnetic resonance spectroscopy: An in vivo method of estimating hippocampal neuronal depletion in schizophrenia
    • Maier M., Ron M.A., Barker G.J., Tofts P.S. Proton magnetic resonance spectroscopy: an in vivo method of estimating hippocampal neuronal depletion in schizophrenia. Psychol. Med. 25:1995;1201-1209.
    • (1995) Psychol. Med. , vol.25 , pp. 1201-1209
    • Maier, M.1    Ron, M.A.2    Barker, G.J.3    Tofts, P.S.4
  • 40
    • 0030090886 scopus 로고    scopus 로고
    • Differential regulation of hippocampal AMPA and kainate receptor subunit expression by haloperidol and clozapine
    • Meador-Woodruff J.H., King R.E., Damask S.P., Bovenkerk K.A. Differential regulation of hippocampal AMPA and kainate receptor subunit expression by haloperidol and clozapine. Mol. Psychiatry. 1:1996;41-53.
    • (1996) Mol. Psychiatry , vol.1 , pp. 41-53
    • Meador-Woodruff, J.H.1    King, R.E.2    Damask, S.P.3    Bovenkerk, K.A.4
  • 41
  • 42
    • 0031862340 scopus 로고    scopus 로고
    • Hippocampal volume reduction in schizophrenia as assessed by magnetic resonance imaging: A meta-analytic study
    • Nelson M.D., Saykin A.J., Flashman L.A., Riordan H.J. Hippocampal volume reduction in schizophrenia as assessed by magnetic resonance imaging: a meta-analytic study. Arch. Gen. Psychiatry. 55:1998;433-440.
    • (1998) Arch. Gen. Psychiatry , vol.55 , pp. 433-440
    • Nelson, M.D.1    Saykin, A.J.2    Flashman, L.A.3    Riordan, H.J.4
  • 44
    • 0030746614 scopus 로고    scopus 로고
    • Antipsychotic regulation of hippocampal dopamine receptor messenger RNA expression
    • Ritter L.M., Meador-Woodruff J.H. Antipsychotic regulation of hippocampal dopamine receptor messenger RNA expression. Biol. Psychiatry. 42:1997;155-164.
    • (1997) Biol. Psychiatry , vol.42 , pp. 155-164
    • Ritter, L.M.1    Meador-Woodruff, J.H.2
  • 47
    • 0031557131 scopus 로고    scopus 로고
    • Neuropsychological profiles in schizophrenia: Paranoid versus undifferentiated distinctions
    • 2
    • Seltzer J., Conrad C., Cassens G. Neuropsychological profiles in schizophrenia: paranoid versus undifferentiated distinctions. Schizophr. Res. 7:(23(2)):1997;131-138.
    • (1997) Schizophr. Res. , vol.7 , Issue.23 , pp. 131-138
    • Seltzer, J.1    Conrad, C.2    Cassens, G.3
  • 50
    • 0025994795 scopus 로고
    • The medial temporal lobe memory system
    • Squire L.R., Zola-Morgan S. The medial temporal lobe memory system. Science. 253:1991;1380-1386.
    • (1991) Science , vol.253 , pp. 1380-1386
    • Squire, L.R.1    Zola-Morgan, S.2
  • 52
    • 0031720755 scopus 로고    scopus 로고
    • Using animal model of deficient sensorimotor gating to study the pathophysiology and new treatment of schizophrenia
    • Swerdlow N.R., Geyer M.A. Using animal model of deficient sensorimotor gating to study the pathophysiology and new treatment of schizophrenia. Schiz. Bull. 24:1998;285-301.
    • (1998) Schiz. Bull. , vol.24 , pp. 285-301
    • Swerdlow, N.R.1    Geyer, M.A.2
  • 53
    • 0028810381 scopus 로고
    • Increased sensitivity to the gating-disruptive effects of apomorphine after lesions of the medial prefrontal cortex or ventral hippocampus in adult rats
    • Swerdlow N.R., Lipska B.K., Weinberger D.R., Braff D.L., Jaskiw G.E., Geyer M.A. Increased sensitivity to the gating-disruptive effects of apomorphine after lesions of the medial prefrontal cortex or ventral hippocampus in adult rats. Psychopharmacology. 122:1995;27-34.
    • (1995) Psychopharmacology , vol.122 , pp. 27-34
    • Swerdlow, N.R.1    Lipska, B.K.2    Weinberger, D.R.3    Braff, D.L.4    Jaskiw, G.E.5    Geyer, M.A.6
  • 54
    • 0026659790 scopus 로고
    • Limbic system abnormalities identified in schizophrenia using emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome
    • Tamminga C.A., Thaker G.K., Buchanan R., Kirkpatrick B., Alphs L.D., Chase T.N., Carpenter W.T. Limbic system abnormalities identified in schizophrenia using emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome. Arch. Gen. Psychiatry. 49:1992;522-530.
    • (1992) Arch. Gen. Psychiatry , vol.49 , pp. 522-530
    • Tamminga, C.A.1    Thaker, G.K.2    Buchanan, R.3    Kirkpatrick, B.4    Alphs, L.D.5    Chase, T.N.6    Carpenter, W.T.7
  • 55
    • 0031574169 scopus 로고    scopus 로고
    • Lack of an association between delayed memory and hippocampal and temporal lobe size in patients with schizophrenia and healthy controls
    • Torres I.J., Flashman L.A., O'Leary D.S., Swayze I.V., Andreasen N.C. Lack of an association between delayed memory and hippocampal and temporal lobe size in patients with schizophrenia and healthy controls. Biol. Psychiatry. 42:1997;1087-1096.
    • (1997) Biol. Psychiatry , vol.42 , pp. 1087-1096
    • Torres, I.J.1    Flashman, L.A.2    O'Leary, D.S.3    Swayze, I.V.4    Andreasen, N.C.5
  • 56
    • 0016299044 scopus 로고
    • Schizophrenia and the limbic system
    • Torrey E.F., Peterson M.R. Schizophrenia and the limbic system. Lancet. 2:1974;942-946.
    • (1974) Lancet , vol.2 , pp. 942-946
    • Torrey, E.F.1    Peterson, M.R.2
  • 57
    • 0025253934 scopus 로고
    • Lack of effect of chronic dopamine blockade on D2 receptor mRNA level
    • Van Tol H.H.M., Riva M., Civelli O., Creese I. Lack of effect of chronic dopamine blockade on D2 receptor mRNA level. Neurosci. Lett. 11:1990;303-308.
    • (1990) Neurosci. Lett. , vol.11 , pp. 303-308
    • Van Tol, H.H.M.1    Riva, M.2    Civelli, O.3    Creese, I.4
  • 60
    • 0033557735 scopus 로고    scopus 로고
    • Cell biology of the hippocampal formation in schizophrenia
    • Weinberger D.R. Cell biology of the hippocampal formation in schizophrenia. Biol. Psychiatry. 45:1999;395-402.
    • (1999) Biol. Psychiatry , vol.45 , pp. 395-402
    • Weinberger, D.R.1
  • 62
    • 0030955717 scopus 로고    scopus 로고
    • Size, shape, and orientation of neurons in the left and right hippocampus: Investigation of normal asymmetries and alternations in schizophrenia
    • Zaidel D.W., Esiri M.M., Harrison P.J. Size, shape, and orientation of neurons in the left and right hippocampus: investigation of normal asymmetries and alternations in schizophrenia. Am. J. Psychaitry. 154:1997;812-818.
    • (1997) Am. J. Psychaitry , vol.154 , pp. 812-818
    • Zaidel, D.W.1    Esiri, M.M.2    Harrison, P.J.3
  • 63
    • 0030962980 scopus 로고    scopus 로고
    • The hippocampus in schizophrenia: Lateralized increase in neuronal denstiy and altered cytoarchitectural asymmetry
    • Zaidel D.W., Esiri M.M., Harrison P.J. The hippocampus in schizophrenia: lateralized increase in neuronal denstiy and altered cytoarchitectural asymmetry. Psychol. Med. 27:1997;703-713.
    • (1997) Psychol. Med. , vol.27 , pp. 703-713
    • Zaidel, D.W.1    Esiri, M.M.2    Harrison, P.J.3
  • 64
    • 0031974611 scopus 로고    scopus 로고
    • New insights into schizophrenia from neuroimaging
    • Zipursky R.B., Kapur S. New insights into schizophrenia from neuroimaging. Curr. Opin. Psychiatry. 11:1998;33-37.
    • (1998) Curr. Opin. Psychiatry , vol.11 , pp. 33-37
    • Zipursky, R.B.1    Kapur, S.2


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