Lack of an association between delayed memory and hippocampal and temporal lobe size in patients with schizophrenia and healthy controls

Biological Psychiatry

Volumn 42, Issue 12, 1997, Pages 1087-1096

  Torres, Ivan J ^a   Flashman, Laura A ^b   O'Leary, Daniel S ^c   Swayze II, Victor ^c   Andreasen, Nancy C ^c  

^a UNIVERSITY OF CHICAGO   (United States)

^b New Hampshire Dartmouth Psychiatric Research Center   (United States)

^c UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Consolidation; Explicit memory; Magnetic resonance imaging; Morphometry; Neuroimaging; Neuropsychology

Indexed keywords

ADULT; AGING; AMNESIA; ARTICLE; BRAIN ATROPHY; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; HUMAN; MALE; MEMORY; NEUROPSYCHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SCHIZOPHRENIA; TEMPORAL LOBE;

ADULT; FEMALE; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; TEMPORAL LOBE;

EID: 0031574169     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(97)00024-3     Document Type: Article

References (76)

1. Andreasen NC, Cohen G, Harris G (1993): Image processing for the study of brain structure and function: Problems and programs. J Neuropsychiatry Clin Neurosci 4:125-133.
2. Andreasen NC, Flashman LA, Flaum M, Arndt S, Swayze V II, O'Leary DS, et al (1994a): Regional brain abnormalities in schizophrenia measured with magnetic resonance imaging. JAMA 272:1763-1769.
3. Andreasen NC, Arndt S, Swayze V II, Cizadlo T, Raum M, O'Leary D, et al (1994b): Thalamic abnormalities in schizophrenia visualized through magnetic resonance image averaging. Science 266:294-298.
4. Andreasen NC, O'Leary DS, Arndt S, Cizadlo T, Hurtig R, Rezai K, et al (1995): Short-term and long-term verbal memory: A positron emission tomography study. Proc Natl Acad Sci USA 92:1-5.
5. Arndt S, Cohen G, Alliger RJ, Swayze VW, Andreasen NC (1991): Problems with ratio and proportion measures of imaged cerebral structures. Psychiatry Res Neuroimaging 40:79-89.
6. Arnold SE, Franz BR, Gur RC, Gur RE, Shapiro RM, Moberg PJ, et al (1995): Smaller neuron size in schizophrenia in hippocampal subfields that mediate cortical-hippocampal interactions. Am J Psychiatry 152:738-748.
7. Beatty WW, Zeijko J, Monson N, Staton RD (1993): Memory and frontal lobe dysfunction in schizophrenia and schizoaffective disorder. J Nerv Ment Dis 181:448-453.
8. Benes FM, Sorensen I, Bird ED (1991): Reduced neuronal size in posterior hippocampus of schizophrenic patients. Schizophr Bull 17:597-608.
9. Bilder RM, Bogerts B, Ashtari M, Wu H, Alvir JM, Jody D, et al (1995): Anterior hippocampal volume reductions predict "frontal lobe" dysfunction in first episode schizophrenia. Schizophr Res 17:47-58.
10. Blanchard JJ, Neale JM (1994): The neuropsychological signature of schizophrenia: Generalized or differential deficit. Am J Psychiatry 151:40-48.
11. Blaxton TA, Bookheimer SY, Zeffiro TA, Figlozzi CM, Gaillard WD, Theodore WH (1996): Functional mapping of human memory using PET: Comparisons of conceptual and perceptual tasks. Can J Exp Psychol 50:42-56.
12. Bogerts B, Meertz E, Schonfeldt-Bausch R (1985): Basal ganglia and limbic system pathology in schizophrenia. Arch Gen Psychiatry 42:784-791.
13. Bogerts B, Ashtari M, Degreef G, Alvir JMJ, Bilder RM, Lieberman JA (1990a): Reduced temporal limbic structure volumes on magnetic resonance images in first-episode schizophrenia. Psychiatry Res 35:1-13.
14. Bogerts B, Falkai P, Haupts M, Greve B, Ernst S, Tapernon-Franz U, et al (1990b): Post-mortem volume measurements of limbic system and basal ganglia structures in chronic schizophrenics: Initial results from a new brain collection. Schizophr Res 3:295-301.
15. Bogerts B, Lieberman JA, Ashtari M, Bilder RM, Degreef G, Lerner G, et al (1993a): Hippocampus-amygdala volumes and psychopathology in chronic schizophrenia. Biol Psychiatry 33:236-246.
16. Bogerts B, Falkai P, Greve B, Schneider T, Pfeiffer U (1993b): The neuropathology of schizophrenia: Past and present. J Hirnforsch 34:193-205.
17. Breier A, Buchanan RW, Elkashef A, Munson RC, Kirkpatrick B, Gellad F (1992): Brain morphology and schizophrenia: A magnetic resonance imaging study of limbic prefrontal cortex and caudate structures. Arch Gen Psychiatry 49:921-926.
18. Buchanan RW, Brier A, Kirkpatrick B, Elkashef A, Munson RC, Gellad F, et al (1993): Structural abnormalities in deficit and nondeficit schizophrenia. Am J Psychiatry 150:59-65.
19. Buckner RL, Petersen SE, Ojemann JG, Miezin FM, Squire LR, Raichle ME (1995): Functional anatomical studies of explicit and implicit memory retrieval tasks. J Neurosci 15:12-29.
20. Calev A, Korin Y, Kugelmass S, Lerer B (1987): Performance of chronic schizophrenics on matched word and design recall tasks. Biol Psychiatry 22:699-709.
21. Coffey CE, Wilkinson WE, Parashos IA, Soady SAR, Sullivan RJ, Patterson LJ, et al (1992): Quantitative cerebral anatomy of the aging human brain: A cross-sectional study using magnetic resonance imaging. Neurology 42:527-536.
22. Colombo C, Abbruzzese M, Livian S, Scotti G, Locatelli M, Bonfanti A, et al (1993): Memory functions and temporal-limbic morphology in schizophrenia. Psychiatry Res Neuroimaging 50:45-56.
23. DeLisi LE, Hoff AL, Schwartz JE, Shields GW, Halthore SN, Gupta SM, et al (1991): Brain morphology in first-episode schizophrenic-like psychotic patients: A quantitative magnetic resonance imaging study. Biol Psychiatry 29:159-175.
24. DeWeer B, Lehericy S, Pillon B, Baulac M, Chiras J, Marsault C, et al (1995): Memory disorders in probable Alzheimer's disease: The role of hippocampal atrophy as shown with MRI. J Neurol Neurosurg Psychiatry 58:590-597.
25. Duvernoy HM (1988): The Human Hippocampus: An Atlas of Applied Anatomy. Munich: Bergmann.
26. Falkai P, Bogerts B, Rozumek M (1986): Cell loss in the hippocampus of schizophrenics. Eur Arch Psychiatry Neurol Sci 236:154-161.
27. Raum M, Swayze VW II, O'Leary DS, Yuh WTC, Ehrhardt JC, Arndt SV, et al (1995): Brain morphology in schizophrenia: Effects of diagnosis, laterality, and gender. Am J Psychiatry 152:704-714.
28. Gold JM, Randolph C, Carpenter CJ, Goldberg TE, Weinberger DR (1992): Forms of memory failure in schizophrenia. J Abnorm Psychol 101:487-494.
29. Goldberg TE, Torrey EF, Gold JM, Ragland JD, Bigelow LB, Weinberger DR (1993): Learning and memory in monozygotic twins discordant for schizophrenia. Psychol Med 23:71-85.
30. Golomb J, Kluger A, deLeon MJ, Ferris SH, Convit A, Mittelman MS, et al (1994): Hippocampal formation size in normal human aging. Learn Mem 1:45-54.
31. Grasby PM, Frith CD, Fristen KJ, Frackowiak RSJ, Dolan RJ (1993): Activation of the human hippocampal formation during auditory-verbal long-term memory function. Neurosci Lett 163:185-188.
32. Heckers S, Heinsen H, Heinsen YC, Beckmann H (1990): Limbic structures and lateral ventricle in schizophrenia. Arch Gen Psychiatry 47:1016-1022.
33. Heckers S, Heinsen H, Geiger B, Beckmann H (1991): Hippocampal neuron number in schizophrenia. Arch Gen Psychiatry 48:1002-1008.
34. Howard R, Mellers J, Petty R, Bonner D, Menon R, Almeida O, et al (1995): Magnetic resonance imaging volumetric measurements of the superior temporal gyrus, hippocampus, parahippocampal gyrus, frontal and temporal lobes in late paraphrenia. Psychol Med 25:495-503.
35. Jeste DV, Lohr JB (1989): Hippocampal pathologic findings in schizophrenia: A morphometric study. Arch Gen Psychiatry 47:1019-1024.
36. Kapur S, Craik FI, Jones C, Brown GM, Houle S, Tulving E (1995a): Functional role of the prefrontal cortex in retrieval of memories: A PET study. Neuroreport 6:1880-1884.
37. Kapur N, Friston KJ, Young A, Frith CD, Frackowiak RS (1995b): Activation of human hippocampal formation during memory for faces: A PET study. Cortex 31:99-108.
38. Kelsoe JR, Lud Cadet J, Pickar D, Weinberger DR (1988): Quantitative neuroanatomy in schizophrenia. Arch Gen Psychiatry 45:533-541.
39. Kemper TL (1994): Neuroanatomical and neuropathological changes during aging and dementia. In: Albert ML, Knoefel JE, editors. Clinical Neurology of Aging, 2nd ed. New York: Oxford University Press, pp 3-67.
40. Killiany RJ, Moss MB, Albert MS, Sandor T (1993): Temporal lobe regions on magnetic resonance imaging identify patients with early Alzheimer's disease. Arch Neurol 50:949-954.
41. Kovelman JA, Scheibel AB (1984): A neurohistological correlate of schizophrenia. Biol Psychiatry 191:601-621.
42. Laakso MP, Soininen H, Partanen K, Helkala EL, Hartikainen P, Vainio P, et al (1995): Volumes of hippocampus, amygdala and frontal lobes in the MRI-based diagnosis of early Alzheimer's disease: Correlation with memory functions. J Neural Transm Gen Sect 9:73-86.
43. Lezak MD (1995): Neuropsychological Assessment, 3rd ed. New York: Oxford University Press.
44. Marsh L, Suddath RL, Higgins N, Weinberger DR (1994): Medial temporal lobe structures in schizophrenia: Relationship of size to duration of illness. Schizophr Res 11:225-238.
45. McCarthy G (1995): Functional neuroimaging of memory. Neuroscientist 1:155-163.
46. Milner B (1972): Disorders of learning and memory after temporal lobe lesions in man. Clin Neurosurg 19:421-446.
47. Mishkin M, Appenzeller T (1987): The anatomy of memory. Sci Am 256:80-89.
48. Nestor PG, Shenton ME, McCarley RW, Haimson J, Smith RS, O'Donnel B, et al (1993): Neuropsychological correlates of MRI temporal lobe abnormalities in schizophrenia. Am J Psychiatry 150:1849-1855.
49. Nyberg L, McIntosh AR, Houle S, Nilsson LG, Tulving E (1996): Activation of medial temporal lobe structures during episodic memory retrieval. Nature 380:715-717.
50. O'Leary DS, Andreasen NC, Hurtig RR (1994): A positron emission tomography study of regional cerebral blood flow during long-and short-term verbal memory. Soc Neurosci Abstr 20:1290.
51. Osterreith PA (1944): Le test de copie d'une figure complex: Contribution a l'etude de la perception et de la memoire. Arch Psychol (Frankf) 30:286-356.
52. Pakkenberg B (1990): Pronounced reduction of total neuron number in mediodorsal thalamic nucleus and nucleus accumbens in schizophrenics. Arch Gen Psychiatry 47:1023-1028.
53. Paulsen JS, Heaton RK, Sadek JR, Perry W, Delis DC, Braff D, et al (1995): The nature of learning and memory impairments in schizophrenia. J Int Neuropsychol Soc 1:88-99.
54. Pfefferbaum A, Marsh L (1995): Structural brain imaging in schizophrenia. Clin Neurosci 3:105-111.
55. Raz N, Torres IJ, Briggs SD, Spencer WD, Thornton AE, Loken WJ, et al (1995): Selective neuroanatomical abnormalities in Down syndrome and their cognitive correlates: Evidence from MRI morphometry. Neurology 45:356-366.
56. Roland PE, Gulyas B (1995): Visual memory, visual imagery, and visual recognition of large field patterns by the human brain: Functional anatomy by positron emission tomography. Cereb Cortex 5:79-93.
57. Rossi A, Stratta P, Mancini F, Galluci M, Mattei P, Core L, et al (1994): Magnetic resonance imaging findings of amygdala-anterior hippocampus shrinkage in male patients with schizophrenia. Psychiatry Res 52:43-53.
58. Sass KJ, Spencer DD, Kim JH, Westerveld M, Novelly RA, Lencz T (1990): Verbal memory impairment correlates with hippocampal pyramidal cell density. Neurology 40:1694-1697.
59. Saykin AJ, Gur RC, Gur RE, Mozley D, Mozley LH, Resnick SM, et al (1991): Neuropsychological function in schizophrenia: Selective impairment in memory and learning. Arch Gen Psychiatry 48:618-624.
60. Schacter DL, Alpert NM, Savage CR, Rauch SL, Albert MS (1996): Conscious recollection and the human hippocampal formation: Evidence from positron emission tomography. Proc Natl Acad Sci USA 93:321-325.
61. Sengel RA, Lovallo WR (1983): Effects of cueing on immediate and recent memory in schizophrenia. J Nerv Ment Dis 171:426-430.
62. Shallice T, Fletcher P, Frith CD, Grasby P, Frackowiak RS, Dolan RJ (1994): Brain regions associated with acquisition and retrieval of verbal episodic memory. Nature 368:633-635.
63. Shenton ME, Kikinis R, Jolesz FA, Pollak SD, LeMay M, Wible CG, et al (1992): Abnormalities of the left temporal lobe and thought disorder in schizophrenia: A quantitative magnetic resonance imaging study. N Engl J Med 327: 604-612.
64. Soininen HS, Partanen K, Pitkanen A, Vainio P, Hanninen T, Hallikainen M, et al (1994): Volumetric MRI analysis of the amygdala and the hippocampus in subjects with age-associated memory impairment: Correlation to visual and verbal memory. Neurology 44:1660-1668.
65. Squire LR, Zola-Morgan S (1991): The medial temporal lobe memory system. Science 253:1380-1386.
66. Squire LR, Ojemann JG, Miezin FM, Petersen SE, Videen TO, Raichle ME (1992): Activation of the hippocampus in normal humans: A functional anatomical study of memory. Proc Natl Acad Sci USA 89:1837-1841.
67. Suddath RL, Christison GW, Torrey EF, Casanova MF, Weinberger DR (1990): Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia. N Engl J Med 322:789-794.
68. Swayze VW, Andreasen NC, Alliger RJ, Yuh WTC, Ehrhardt JC (1992): Subcortical and temporal structures in affective disorder and schizophrenia: A magnetic resonance imaging study. Biol Psychiatry 31:221-240.
69. Talairach J, Tournoux P (1988): Co-Planar Stereotaxic Atlas of the Human Brain. New York: Thieme.
70. Tamlyn D, McKenna PJ, Mortimer AM, Lund CE, Hammond S, Baddeley AD (1992): Memory impairment in schizophrenia: Its extent affiliations and neuropsychological character. Psychol Med 22:101-115.
71. Torres IJ, Flashman LA, O'Leary DS, Andreasen NC (1995): The effects of proactive and retroactive interference on list learning in schizophrenia. J Int Neuropsychol Soc 1:133.
72. Tulving E, Kapur S, Craik FIM, Moscovitch M, Houle S (1994a): Hemispheric encoding/retrieval asymmetry in episodic memory: Positron emission tomography findings. Proc Natl Acad Sci USA 91:2016-2020.
73. Tulving E, Kapur S, Markowitsch HJ, Craik FIM, Habib R, Houle S (1994b): Neuroanatomical correlates of retrieval in episodic memory: Auditory sentence recognition. Proc Natl Acad Sci USA 91:2012-2015.
74. Wechsler D (1987): Wechsler Memory Scale-Revised. New York: The Psychological Corporation.
75. Zipursky RB, Marsh L, Lim KO, DeMent S, Shear P, Sullivan E, et al (1994): Volumetric MRI assessment of temporal lobe structures in schizophrenia. Biol Psychiatry 35:501-516.
76. Zola-Morgan S, Squire LR, Amaral DG (1986): Human amnesia and the medial temporal region: Enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus. J Neurosci 6:2950-2967.