Analysis of thyroid hormone receptor βa mRNA expression in Xenopus laevis tadpoles as a means to detect agonism and antagonism of thyroid hormone action

Toxicology and Applied Pharmacology

Volumn 212, Issue 1, 2006, Pages 1-13

  Opitz, Robert ^a   Lutz, Ilka ^a   Nguyen, Ngoc Ha ^b   Scanlan, Thomas S ^b   Kloas, Werner ^a,c  

^a LEIBNIZ INSTITUTE OF FRESHWATER ECOLOGY AND INLAND FISHERIES   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Amphibian metamorphosis; Endocrine disruption; RT PCR; Thyroid hormone receptors; Xenopus laevis

Indexed keywords

BIOLOGICAL MARKER; GC 1; HORMONE RECEPTOR BLOCKING AGENT; HORMONE RECEPTOR STIMULATING AGENT; LIOTHYRONINE; MESSENGER RNA; NH 3; THYROID HORMONE; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA; THYROXINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; GENE EXPRESSION; HEAD; HORMONE ACTION; IN VIVO STUDY; LIMB DEVELOPMENT; METAMORPHOSIS; NONHUMAN; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TADPOLE; TAIL; XENOPUS LAEVIS;

ACETIC ACIDS; ANIMALS; ANTITHYROID AGENTS; BIOLOGICAL MARKERS; DATA INTERPRETATION, STATISTICAL; DRUG EVALUATION, PRECLINICAL; ENDOCRINE DISRUPTORS; GENE EXPRESSION REGULATION; HINDLIMB; INDICATORS AND REAGENTS; LARVA; METAMORPHOSIS, BIOLOGICAL; PHENOLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THYROID HORMONE RECEPTORS ALPHA; THYROID HORMONE RECEPTORS BETA; THYROID HORMONES; XENOPUS LAEVIS;

AMPHIBIA; ANIMALIA; XENOPUS LAEVIS;

EID: 33644947006     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.06.014     Document Type: Article

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