Analysis of two KCNJ11 neonatal diabetes mutations, V59G and V59A, and the analogous KCNJ8 I60G substitution: Differences between the channel subtypes formed with SUR1

Journal of Biological Chemistry

Volumn 284, Issue 11, 2009, Pages 6752-6762

  Winkler, Marcus ^a   Lutz, Rebekka ^a   Russ, Ulrich ^a   Quast, Ulrich ^a   Bryan, Joseph ^b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b PACIFIC NORTHWEST RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE NUCLEOTIDE; BISPHOSPHATE; CHANNEL ACTIVITY; CHANNEL INHIBITOR; CONCENTRATION OF; CYTOPLASMIC LOOPS; DEVELOPMENTAL DELAY; GLIBENCLAMIDE; NUCLEOTIDE BINDING; OCTAMERS; PHOSPHATIDYLINOSITOL; PHOSPHOINOSITIDE BINDING; PHOSPHOINOSITIDES; POLYLYSINE; REPAGLINIDE; SULFONYLUREA RECEPTORS; SULFONYLUREAS; VASCULAR SMOOTH MUSCLES;

BARIUM; BINDING ENERGY; NUCLEIC ACIDS; NUCLEOTIDES; PHOSPHOLIPIDS; PHOSPHORIC ACID;

BINDING SITES;

ADENOSINE TRIPHOSPHATE; ALANINE; AMINO ACID; BARIUM ION; GLIBENCLAMIDE; GLYCINE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.1; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; ISOLEUCINE; NEOMYCIN; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POLYLYSINE; SULFONYLUREA; SULFONYLUREA RECEPTOR 1; VALINE; ABC TRANSPORTER; DRUG RECEPTOR; INWARDLY RECTIFYING POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; SULFONYLUREA RECEPTOR; UK ATP 1 POTASSIUM CHANNEL; UK-ATP-1 POTASSIUM CHANNEL;

AMINO ACID ANALYSIS; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DIABETES MELLITUS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MUTATIONAL ANALYSIS; NEWBORN DISEASE; PRIORITY JOURNAL; PROTEIN STABILITY; SENSITIVITY ANALYSIS; VASCULAR SMOOTH MUSCLE; CELL LINE; CHANNEL GATING; DRUG EFFECT; EPILEPSY; GENETIC DISORDER; GENETICS; METABOLISM; MISSENSE MUTATION; NEWBORN; SMOOTH MUSCLE FIBER; SYNDROME;

AMINO ACID SUBSTITUTION; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; DEVELOPMENTAL DISABILITIES; DIABETES MELLITUS; EPILEPSY; GENETIC DISEASES, INBORN; HUMANS; INFANT, NEWBORN; ION CHANNEL GATING; MUSCLE, SMOOTH, VASCULAR; MUTATION, MISSENSE; MYOCYTES, SMOOTH MUSCLE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, DRUG; SYNDROME;

EID: 65449130091     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M805435200     Document Type: Article

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