Specific tumor-cell killing with adenovirus vectors containing the apoptin gene

Gene Therapy

Volumn 6, Issue 5, 1999, Pages 882-892

  Pietersen, A M ^a,b   Van Der Eb, M M ^a   Rademaker, H J ^a   Van Den Wollenberg, D J M ^a   Rabelink, M J W E ^a   Kuppen, P J K ^a   Van Dierendonck, J H ^a   Van Ormondt, H ^a   Masman, D ^b   Van De Velde, C J H ^a   Van Der Eb, A J ^a   Hoeben, R C ^a   Noteborn, M H M ^a,b,c  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Leadd BV   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Apoptin; Cancer gene therapy; Recombinant adenovirus; Tumor cell specificity

Indexed keywords

APOPTIN; PROTEIN; PROTEIN BCL 2; PROTEIN P53; UNCLASSIFIED DRUG;

ADENOVIRUS; ADENOVIRUS 5; AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CELL CULTURE; CELL KILLING; CELL TRANSFORMATION; CIRCOVIRIDAE; CONTROLLED STUDY; DIPLOIDY; EMBRYO; EXPRESSION VECTOR; GENE THERAPY; HELPER CELL; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; TUMOR CELL;

ADENOVIRIDAE; ANIMALS; CAPSID; CAPSID PROTEINS; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; INJECTIONS, INTRALESIONAL; INJECTIONS, INTRAVENOUS; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; RATS; RATS, INBRED STRAINS; T-LYMPHOCYTES, HELPER-INDUCER; TUMOR CELLS, CULTURED;

ADENOVIRIDAE; ANIMALIA; CHICKEN ANEMIA VIRUS; CIRCOVIRIDAE; GALLUS GALLUS; HUMAN ADENOVIRUS TYPE 5;

EID: 6544245050     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300876     Document Type: Article

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