메뉴 건너뛰기




Volumn 113, Issue 14, 2009, Pages 3323-3332

Runx2 induces acute myeloid leukemia in cooperation with Cbfp-SMMHC in mice

Author keywords

[No Author keywords available]

Indexed keywords

CELL MARKER; CELL PROTEIN; COLONY STIMULATING FACTOR RECEPTOR; CORE BINDING FACTOR BETA; CORE BINDING FACTOR BETA SMOOTH MUSCLE MYOSIN HEAVY CHAIN; MYELOPEROXIDASE; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

EID: 65349163429     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-06-162248     Document Type: Article
Times cited : (70)

References (61)
  • 1
    • 0027256023 scopus 로고
    • Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor
    • Wang S, Wang Q, Crute BE, Melnikova IN, Keller SR, Speck NA. Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor. Mol Cell Biol. 1993;13:3324-3339.
    • (1993) Mol Cell Biol , vol.13 , pp. 3324-3339
    • Wang, S.1    Wang, Q.2    Crute, B.E.3    Melnikova, I.N.4    Keller, S.R.5    Speck, N.A.6
  • 2
    • 0027184229 scopus 로고
    • Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha
    • Ogawa E, Inuzuka M, Maruyama M, et al. Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha. Virology. 1993;194:314-331.
    • (1993) Virology , vol.194 , pp. 314-331
    • Ogawa, E.1    Inuzuka, M.2    Maruyama, M.3
  • 3
    • 0033585125 scopus 로고    scopus 로고
    • Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/ polyoma enhancer-binding protein 2alphaB/core binding factor alpha2
    • Tang L, Guo B, Javed A, et al. Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/ polyoma enhancer-binding protein 2alphaB/core binding factor alpha2. J Biol Chem. 1999;274: 33580-33586.
    • (1999) J Biol Chem , vol.274 , pp. 33580-33586
    • Tang, L.1    Guo, B.2    Javed, A.3
  • 4
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • Okuda T, van Deursen J, Hiebert SW, Grosveld G, Downing JR. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell. 1996;84:321-330.
    • (1996) Cell , vol.84 , pp. 321-330
    • Okuda, T.1    van Deursen, J.2    Hiebert, S.W.3    Grosveld, G.4    Downing, J.R.5
  • 5
    • 0029918597 scopus 로고    scopus 로고
    • Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive he- matopoiesis
    • Wang Q, Stacy T, Binder M, Marin-Padilla M, Sharpe AH, Speck NA. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive he- matopoiesis. Proc Natl Acad Sci USA. 1996;93:3444-3449.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3444-3449
    • Wang, Q.1    Stacy, T.2    Binder, M.3    Marin-Padilla, M.4    Sharpe, A.H.5    Speck, N.A.6
  • 6
    • 0030588487 scopus 로고    scopus 로고
    • The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo
    • Wang Q, Stacy T, Miller JD, et al. The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo. Cell. 1996;87:697-708.
    • (1996) Cell , vol.87 , pp. 697-708
    • Wang, Q.1    Stacy, T.2    Miller, J.D.3
  • 7
    • 0035135174 scopus 로고    scopus 로고
    • Requirement of Runx1/AML1/ PEBP2alphaB for the generation of haematopoietic cells from endothelial cells
    • Yokomizo T, Ogawa M, Osato M, et al. Requirement of Runx1/AML1/ PEBP2alphaB for the generation of haematopoietic cells from endothelial cells. Genes Cells. 2001;6:13-23.
    • (2001) Genes Cells , vol.6 , pp. 13-23
    • Yokomizo, T.1    Ogawa, M.2    Osato, M.3
  • 8
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation because of maturational arrest of osteoblasts
    • Komori T, Yagi H, Nomura S, et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation because of maturational arrest of osteoblasts. Cell. 1997;89:755-764.
    • (1997) Cell , vol.89 , pp. 755-764
    • Komori, T.1    Yagi, H.2    Nomura, S.3
  • 9
    • 18344372018 scopus 로고    scopus 로고
    • The RUNX genes: Gain or loss of function in cancer
    • Blyth K, Cameron ER, Neil JC. The RUNX genes: gain or loss of function in cancer. Nat Rev Cancer. 2005;5:376-387.
    • (2005) Nat Rev Cancer , vol.5 , pp. 376-387
    • Blyth, K.1    Cameron, E.R.2    Neil, J.C.3
  • 10
    • 0028925282 scopus 로고
    • The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation
    • Meyers S, Lenny N, Hiebert SW. The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation. Mol Cell Biol. 1995;15:1974-1982.
    • (1995) Mol Cell Biol , vol.15 , pp. 1974-1982
    • Meyers, S.1    Lenny, N.2    Hiebert, S.W.3
  • 11
    • 16144362555 scopus 로고    scopus 로고
    • Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11
    • Castilla LH, Wijmenga C, Wang Q, et al. Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11. Cell. 1996;87:687-696.
    • (1996) Cell , vol.87 , pp. 687-696
    • Castilla, L.H.1    Wijmenga, C.2    Wang, Q.3
  • 12
    • 0033559746 scopus 로고    scopus 로고
    • Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2alphaB gene associated with myeloblastic leukemias
    • Osato M, Asou N, Abdalla E, et al. Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2alphaB gene associated with myeloblastic leukemias. Blood. 1999;93:1817-1824.
    • (1999) Blood , vol.93 , pp. 1817-1824
    • Osato, M.1    Asou, N.2    Abdalla, E.3
  • 13
    • 0037438508 scopus 로고    scopus 로고
    • Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia
    • Harada H, Harada Y,Tanaka H, Kimura A, Inaba T. Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia. Blood. 2003;101:673-680.
    • (2003) Blood , vol.101 , pp. 673-680
    • Harada, H.1    Harada, Y.2    Tanaka, H.3    Kimura, A.4    Inaba, T.5
  • 14
    • 4444302228 scopus 로고    scopus 로고
    • Mutations of AML1 are common intherapy related myelodysplasia following therapy with alkylating agents and are significantly associated with deletion or loss of chromosome arm 7q and with subsequent leukemic transformation
    • Christiansen DH, Andersen MK, Pedersen-Bjergaard J, et al. Mutations of AML1 are common intherapy related myelodysplasia following therapy with alkylating agents and are significantly associated with deletion or loss of chromosome arm 7q and with subsequent leukemic transformation. Blood. 2004;104:1474-1481.
    • (2004) Blood , vol.104 , pp. 1474-1481
    • Christiansen, D.H.1    Andersen, M.K.2    Pedersen-Bjergaard, J.3
  • 15
    • 3142620903 scopus 로고    scopus 로고
    • Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia
    • Tartaglia M, Martinelli S, Cazzaniga G, et al. Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia. Blood. 2004;104:307-313.
    • (2004) Blood , vol.104 , pp. 307-313
    • Tartaglia, M.1    Martinelli, S.2    Cazzaniga, G.3
  • 17
    • 0037348975 scopus 로고    scopus 로고
    • Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: A study of 20 cases
    • Harewood L, Robinson H, Harris R, et al. Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: a study of 20 cases. Leukemia. 2003;17:547-553.
    • (2003) Leukemia , vol.17 , pp. 547-553
    • Harewood, L.1    Robinson, H.2    Harris, R.3
  • 19
    • 10744223283 scopus 로고    scopus 로고
    • Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome
    • Robinson HM, Broadfield ZJ, Cheung KL, et al. Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome. Leukemia. 2003;17:2249-2250.
    • (2003) Leukemia , vol.17 , pp. 2249-2250
    • Robinson, H.M.1    Broadfield, Z.J.2    Cheung, K.L.3
  • 20
    • 13544273521 scopus 로고    scopus 로고
    • Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML
    • Andersen MK, Christiansen DH, Pedersen Bjergaard J. Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML. Leukemia. 2005;19:197-200.
    • (2005) Leukemia , vol.19 , pp. 197-200
    • Andersen, M.K.1    Christiansen, D.H.2    Pedersen Bjergaard, J.3
  • 21
    • 33749179382 scopus 로고    scopus 로고
    • High-level amplification of the RUNX1 gene in two cases of childhood acute lymphoblastic leukemia
    • Garcia-Casado Z, Cervera J, Verdeguer A, et al. High-level amplification of the RUNX1 gene in two cases of childhood acute lymphoblastic leukemia. Cancer Genet Cytogenet. 2006;170:171-174.
    • (2006) Cancer Genet Cytogenet , vol.170 , pp. 171-174
    • Garcia-Casado, Z.1    Cervera, J.2    Verdeguer, A.3
  • 22
    • 33645470588 scopus 로고    scopus 로고
    • Amplification of AML1 gene in association with karyotype, age and diagnosis in acute leukemia patients
    • Kirschnerova G, Tothova A, Babusikova O. Amplification of AML1 gene in association with karyotype, age and diagnosis in acute leukemia patients. Neoplasma. 2006;53:150-154.
    • (2006) Neoplasma , vol.53 , pp. 150-154
    • Kirschnerova, G.1    Tothova, A.2    Babusikova, O.3
  • 23
    • 85014143894 scopus 로고    scopus 로고
    • AML1 gene over-expression in childhood acute lymphoblastic leukemia
    • Mikhail FM, Serry KA, Hatem N, et al. AML1 gene over-expression in childhood acute lymphoblastic leukemia. Leukemia. 2002;16:658-668.
    • (2002) Leukemia , vol.16 , pp. 658-668
    • Mikhail, F.M.1    Serry, K.A.2    Hatem, N.3
  • 24
    • 0030052663 scopus 로고    scopus 로고
    • til-1: A novel proviral insertion locus for Moloney murine leukaemia virus in lym- phomas of CD2-myc transgenic mice
    • Stewart M, Terry A, O'Hara M, Cameron E, Onions D, Neil JC. til-1: a novel proviral insertion locus for Moloney murine leukaemia virus in lym- phomas of CD2-myc transgenic mice. J Gen Virol. 1996;77:443-446.
    • (1996) J Gen Virol , vol.77 , pp. 443-446
    • Stewart, M.1    Terry, A.2    O'Hara, M.3    Cameron, E.4    Onions, D.5    Neil, J.C.6
  • 25
    • 0030741019 scopus 로고    scopus 로고
    • Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): Evidence for a new myc collaborating oncogene
    • Stewart M, Terry A, Hu M, et al. Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene. Proc Natl Acad Sci USA. 1997;94:8646-8651.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8646-8651
    • Stewart, M.1    Terry, A.2    Hu, M.3
  • 26
    • 0033604455 scopus 로고    scopus 로고
    • A full-length Cbfa1 gene product perturbs T-cell development and promotes lymphomagenesis in synergy with myc
    • Vaillant F, Blyth K, Terry A, et al. A full-length Cbfa1 gene product perturbs T-cell development and promotes lymphomagenesis in synergy with myc. Oncogene. 1999;18:7124-7134.
    • (1999) Oncogene , vol.18 , pp. 7124-7134
    • Vaillant, F.1    Blyth, K.2    Terry, A.3
  • 27
    • 0036223379 scopus 로고    scopus 로고
    • The common retroviral insertion locus Dsi1 maps 30 kilobases upstream of the P1 promoter of the murine Runx3/Cbfa3/Aml2 gene
    • Stewart M, MacKay N, Cameron ER, Neil JC. The common retroviral insertion locus Dsi1 maps 30 kilobases upstream of the P1 promoter of the murine Runx3/Cbfa3/Aml2 gene. J Virol. 2002;76: 4364-4369.
    • (2002) J Virol , vol.76 , pp. 4364-4369
    • Stewart, M.1    MacKay, N.2    Cameron, E.R.3    Neil, J.C.4
  • 28
    • 0037115419 scopus 로고    scopus 로고
    • Proviral insertion indicates a dominant oncogenic role for Runx1/AML-1 in T-cell lymphoma
    • Wotton S, Stewart M, Blyth K, et al. Proviral insertion indicates a dominant oncogenic role for Runx1/AML-1 in T-cell lymphoma. Cancer Res. 2002;62:7181-7185.
    • (2002) Cancer Res , vol.62 , pp. 7181-7185
    • Wotton, S.1    Stewart, M.2    Blyth, K.3
  • 29
    • 0032726951 scopus 로고    scopus 로고
    • Leukaemia disease genes: Large-scale cloning and pathway predictions
    • Li J, Shen H, Himmel KL, et al. Leukaemia disease genes: large-scale cloning and pathway predictions. Nat Genet. 1999;23:348-353.
    • (1999) Nat Genet , vol.23 , pp. 348-353
    • Li, J.1    Shen, H.2    Himmel, K.L.3
  • 30
    • 0036729878 scopus 로고    scopus 로고
    • High throughput retroviral tagging to identify components of specific signaling pathways in cancer
    • Mikkers H, Allen J, Knipscheer P, et al. High throughput retroviral tagging to identify components of specific signaling pathways in cancer. Nat Genet. 2002;32:153-159.
    • (2002) Nat Genet , vol.32 , pp. 153-159
    • Mikkers, H.1    Allen, J.2    Knipscheer, P.3
  • 31
    • 33644916915 scopus 로고    scopus 로고
    • Increased dosage of the RUNX1/ AML1 gene: Athird mode of RUNX leukemia?
    • Osato M, Ito Y. Increased dosage of the RUNX1/ AML1 gene: athird mode of RUNX leukemia? Crit Rev Eukaryot Gene Expr. 2005;15:217-228.
    • (2005) Crit Rev Eukaryot Gene Expr , vol.15 , pp. 217-228
    • Osato, M.1    Ito, Y.2
  • 32
    • 22744435139 scopus 로고    scopus 로고
    • Increased dosage of Runx1/AML1 acts as a positive modulator of myeloid leukemogenesis in BXH2 mice
    • Yanagida M, Osato M, Yamashita N, et al. Increased dosage of Runx1/AML1 acts as a positive modulator of myeloid leukemogenesis in BXH2 mice. Oncogene. 2005;24:4477-4485.
    • (2005) Oncogene , vol.24 , pp. 4477-4485
    • Yanagida, M.1    Osato, M.2    Yamashita, N.3
  • 33
    • 0032878921 scopus 로고    scopus 로고
    • The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia
    • Castilla LH, Garrett L, Adya N, et al.The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia. Nat Genet. 1999;23:144-146.
    • (1999) Nat Genet , vol.23 , pp. 144-146
    • Castilla, L.H.1    Garrett, L.2    Adya, N.3
  • 34
    • 30344446665 scopus 로고    scopus 로고
    • Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia
    • Kuo YH, Landrette SF, Heilman SA, et al. Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia. Cancer Cell. 2006;9:57-68.
    • (2006) Cancer Cell , vol.9 , pp. 57-68
    • Kuo, Y.H.1    Landrette, S.F.2    Heilman, S.A.3
  • 35
    • 11144353866 scopus 로고    scopus 로고
    • Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia
    • Castilla LH, Perrat P, Martinez NJ, et al. Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia. Proc Natl Acad Sci USA. 2004;101:4924-4929.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4924-4929
    • Castilla, L.H.1    Perrat, P.2    Martinez, N.J.3
  • 36
    • 0035902565 scopus 로고    scopus 로고
    • Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development
    • Choi JY, Pratap J, Javed A, et al. Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development. Proc Natl Acad Sci USA. 2001;98: 8650-8655.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8650-8655
    • Choi, J.Y.1    Pratap, J.2    Javed, A.3
  • 38
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • Akashi K, Traver D, Miyamoto T, Weissman IL. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature. 2000;404:193-197.
    • (2000) Nature , vol.404 , pp. 193-197
    • Akashi, K.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4
  • 39
    • 0035807964 scopus 로고    scopus 로고
    • Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells
    • Christensen JL, Weissman IL. Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells. Proc Natl Acad Sci U S A. 2001;98:14541-14546.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 14541-14546
    • Christensen, J.L.1    Weissman, I.L.2
  • 40
    • 0030987304 scopus 로고    scopus 로고
    • Identification of a lineage of multipotent hematopoietic progenitors: The long- term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
    • Morrison SJ, Wandycz AM, Hemmati HD, Wright DE, Weissman IL. Identification of a lineage of multipotent hematopoietic progenitors: the long- term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Development. 1997;124:1929-1939.
    • (1997) Development , vol.124 , pp. 1929-1939
    • Morrison, S.J.1    Wandycz, A.M.2    Hemmati, H.D.3    Wright, D.E.4    Weissman, I.L.5
  • 41
    • 0028534860 scopus 로고
    • The long-term re- populating subset of hematopoietic stem cells is deterministic and isolatable byphenotype
    • Morrison SJ, Weissman IL. The long-term re- populating subset of hematopoietic stem cells is deterministic and isolatable byphenotype. Immunity. 1994;1:661-673.
    • (1994) Immunity , vol.1 , pp. 661-673
    • Morrison, S.J.1    Weissman, I.L.2
  • 42
    • 33847634759 scopus 로고    scopus 로고
    • Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2
    • Young DW, Hassan MQ, Yang XQ, et al. Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2. Proc Natl Acad Sci USA. 2007;104:3189-3194.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 3189-3194
    • Young, D.W.1    Hassan, M.Q.2    Yang, X.Q.3
  • 43
    • 0028066779 scopus 로고
    • PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells
    • Nuchprayoon I, Meyers S, Scott LM, Suzow J, Hiebert S, Friedman AD. PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells. Mol Cell Biol. 1994;14:5558-5568.
    • (1994) Mol Cell Biol , vol.14 , pp. 5558-5568
    • Nuchprayoon, I.1    Meyers, S.2    Scott, L.M.3    Suzow, J.4    Hiebert, S.5    Friedman, A.D.6
  • 44
    • 0027984233 scopus 로고
    • Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1)
    • Zhang DE, Fujioka K, Hetherington CJ, et al. Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1). Mol Cell Biol. 1994;14:8085-8095.
    • (1994) Mol Cell Biol , vol.14 , pp. 8085-8095
    • Zhang, D.E.1    Fujioka, K.2    Hetherington, C.J.3
  • 45
    • 0034614382 scopus 로고    scopus 로고
    • A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia
    • Lutterbach B, Westendorf JJ, Linggi B, Isaac S, Seto E, Hiebert SW. A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia. J Biol Chem. 2000;275:651-656.
    • (2000) J Biol Chem , vol.275 , pp. 651-656
    • Lutterbach, B.1    Westendorf, J.J.2    Linggi, B.3    Isaac, S.4    Seto, E.5    Hiebert, S.W.6
  • 46
    • 0036840499 scopus 로고    scopus 로고
    • Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter
    • Westendorf JJ, Zaidi SK, Cascino JE, et al. Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. Mol Cell Biol. 2002;22:7982- 7992.
    • (2002) Mol Cell Biol , vol.22 , pp. 7982-7992
    • Westendorf, J.J.1    Zaidi, S.K.2    Cascino, J.E.3
  • 47
    • 0034647543 scopus 로고    scopus 로고
    • Runt domain factor (Runx)-dependent effects on CCAAT/ enhancer-binding protein delta expression and activity in osteoblasts
    • McCarthy TL, Ji C, Chen Y, et al. Runt domain factor (Runx)-dependent effects on CCAAT/ enhancer-binding protein delta expression and activity in osteoblasts. J Biol Chem. 2000;275:21746-21753.
    • (2000) J Biol Chem , vol.275 , pp. 21746-21753
    • McCarthy, T.L.1    Ji, C.2    Chen, Y.3
  • 48
    • 0042878458 scopus 로고    scopus 로고
    • Energetic contribution of residues in the Runx1 Runt domain to DNA binding
    • Li Z, Yan J, Matheny CJ, et al. Energetic contribution of residues in the Runx1 Runt domain to DNA binding. J Biol Chem. 2003;278:33088- 33096.
    • (2003) J Biol Chem , vol.278 , pp. 33088-33096
    • Li, Z.1    Yan, J.2    Matheny, C.J.3
  • 49
    • 1842457741 scopus 로고    scopus 로고
    • Tyrosine phosphorylation controls Runx2-mediated sub- nuclear targeting of YAP to repress transcription
    • Zaidi SK, Sullivan AJ, Medina R, et al. Tyrosine phosphorylation controls Runx2-mediated sub- nuclear targeting of YAP to repress transcription. EMBO J. 2004;23:790-799.
    • (2004) EMBO J , vol.23 , pp. 790-799
    • Zaidi, S.K.1    Sullivan, A.J.2    Medina, R.3
  • 50
    • 0033522472 scopus 로고    scopus 로고
    • A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator
    • Yagi R, Chen LF, Shigesada K, Murakami Y, Ito Y. A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J. 1999;18:2551-2562.
    • (1999) EMBO J , vol.18 , pp. 2551-2562
    • Yagi, R.1    Chen, L.F.2    Shigesada, K.3    Murakami, Y.4    Ito, Y.5
  • 51
    • 33750495807 scopus 로고    scopus 로고
    • Alterations in intranuclear localization of Runx2 affect biological activity
    • Zaidi SK, Javed A, Pratap J, et al. Alterations in intranuclear localization of Runx2 affect biological activity. J Cell Physiol. 2006;209:935-942.
    • (2006) J Cell Physiol , vol.209 , pp. 935-942
    • Zaidi, S.K.1    Javed, A.2    Pratap, J.3
  • 52
    • 34347213447 scopus 로고    scopus 로고
    • Retroviral insertional mutagenesis identifies genes that collaborate with NUP98HOXD13 during leukemic transformation
    • Slape C, Hartung H, Lin YW, Bies J, WolffL, Aplan PD. Retroviral insertional mutagenesis identifies genes that collaborate with NUP98HOXD13 during leukemic transformation. Cancer Res. 2007;67:5148-5155.
    • (2007) Cancer Res , vol.67 , pp. 5148-5155
    • Slape, C.1    Hartung, H.2    Lin, Y.W.3    Bies, J.4    Wolff, L.5    Aplan, P.D.6
  • 53
    • 33746498580 scopus 로고    scopus 로고
    • Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
    • Krivtsov AV, Twomey D, Feng Z, et al. Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature. 2006;442:818-822.
    • (2006) Nature , vol.442 , pp. 818-822
    • Krivtsov, A.V.1    Twomey, D.2    Feng, Z.3
  • 54
    • 23944447687 scopus 로고    scopus 로고
    • Control of RUNX2 isoform expression: The role of promoters and enhancers
    • Stock M, Otto F. Control of RUNX2 isoform expression: the role of promoters and enhancers. J Cell Biochem. 2005;95:506-517.
    • (2005) J Cell Biochem , vol.95 , pp. 506-517
    • Stock, M.1    Otto, F.2
  • 55
  • 56
    • 38049155882 scopus 로고    scopus 로고
    • Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tu- morigenic potential
    • Zaidi SK, Pande S, Pratap J, et al. Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tu- morigenic potential. Proc Natl Acad Sci U S A. 2007;104:19861-19866.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 19861-19866
    • Zaidi, S.K.1    Pande, S.2    Pratap, J.3
  • 57
    • 42449103970 scopus 로고    scopus 로고
    • The RUNX2 transcription factor cooperates with the YES- associated protein, YAP65, to promote cell transformation
    • Vitolo MI, Anglin IE, Mahoney WM Jr, et al. The RUNX2 transcription factor cooperates with the YES- associated protein, YAP65, to promote cell transformation. Cancer Biol Ther. 2007;6:856-863.
    • (2007) Cancer Biol Ther , vol.6 , pp. 856-863
    • Vitolo, M.I.1    Anglin, I.E.2    Mahoney Jr, W.M.3
  • 58
    • 39749130325 scopus 로고    scopus 로고
    • Histone deacetylase 7 associates with Runx2 and represses its activity during osteoblast maturation in a deacetylation-independent manner
    • Jensen ED, Schroeder TM, Bailey J, Gopalakrishnan R, Westendorf JJ. Histone deacetylase 7 associates with Runx2 and represses its activity during osteoblast maturation in a deacetylation-independent manner. J Bone Miner Res. 2008;23:361-372.
    • (2008) J Bone Miner Res , vol.23 , pp. 361-372
    • Jensen, E.D.1    Schroeder, T.M.2    Bailey, J.3    Gopalakrishnan, R.4    Westendorf, J.J.5
  • 59
    • 34248325702 scopus 로고    scopus 로고
    • The p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO
    • Peterson LF, Yan M, Zhang DE. The p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO. Blood. 2007;109:4392-4398.
    • (2007) Blood , vol.109 , pp. 4392-4398
    • Peterson, L.F.1    Yan, M.2    Zhang, D.E.3
  • 60
    • 18744398397 scopus 로고    scopus 로고
    • Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
    • Taniuchi I, Osato M, EgawaT, et al. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell. 2002;111:621-633.
    • (2002) Cell , vol.111 , pp. 621-633
    • Taniuchi, I.1    Osato, M.2    EgawaT3
  • 61
    • 0037105587 scopus 로고    scopus 로고
    • Enforced expression of Runx2 perturbs T cell development at a stage coincident with beta- selection
    • Vaillant F, Blyth K, Andrew L, Neil JC, Cameron ER. Enforced expression of Runx2 perturbs T cell development at a stage coincident with beta- selection. J Immunol. 2002;169:2866-2874.
    • (2002) J Immunol , vol.169 , pp. 2866-2874
    • Vaillant, F.1    Blyth, K.2    Andrew, L.3    Neil, J.C.4    Cameron, E.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.