Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome [9]

Leukemia

Volumn 17, Issue 11, 2003, Pages 2249-2250

  Robinson, H M ^a   Broadfield, Z J ^a   Cheung, K L ^a   Harewood, L ^a   Harris, R L ^a   Jalali, G R ^a   Martineau, M ^a   Moorman, A V ^a   Taylor, K E ^a   Richards, S ^b   Mitchell, C ^c   Harrison, C J ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b RADCLIFFE INFIRMARY   (United Kingdom)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTILEUKEMIC AGENT;

ACUTE LYMPHOBLASTIC LEUKEMIA; BONE MARROW; CANCER PATIENT; CANCER RECURRENCE; CANCER SURVIVAL; CELL ISOLATION; CHILD; CHROMOSOME 21; CHROMOSOME ANALYSIS; CHROMOSOME DUPLICATION; CLINICAL ARTICLE; CONTROLLED STUDY; EXON; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; GENE AMPLIFICATION; HUMAN; IMMUNOPHENOTYPING; KARYOTYPE; LETTER; LEUKEMIA REMISSION; LEUKOCYTE COUNT; MALE; MONOSOMY; PRIORITY JOURNAL; SIDE EFFECT; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 10744223283     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403140     Document Type: Letter

References (5)

1. Harewood L, Robinson H, Harris R, Jabbar Al-Obaidi MS, Jalali GR, Martineau M et al. Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: a study of 20 cases. Leukemia 2003; 17: 547-553.
2. Jabbar Al-Obaidi MS, Martineau M, Bennett CF, Franklin IM, Goldstone AH, Harewood L et al. ETV6/AML1 fusion by FISH in adult acute lymphoblastic leukemia. Leukemia 2002; 16: 669-674.
3. Mikhail FM, Serry KA, Hatem N, Mourad ZI, Farawela HM, El Kaffash DM et al. AML1 gene over-expression in childhood acute lymphoblastic leukemia. Leukemia 2002; 16: 658-668.
4. Morel F, Herry A, Le Bris M-J, Douet-Guilbert N, Le Calvez G, Marion V et al. AML1 amplification in a case of childhood acute lymphoblastic leukemia. Cancer Genet Cytogenet 2002; 137: 142-145.
5. Alvarez Y, Coll MD, Bastida P, Ortega JJ, Caballin MR. AML1 amplification in a child with acute lymphoblastic leukemia. Cancer Genet Cytogenet 2003; 140: 58-61.