메뉴 건너뛰기




Volumn 80, Issue 4, 2009, Pages 622-630

Metabolic and mitochondrial dysfunction in early mouse embryos following maternal dietary protein intervention

Author keywords

Embryo; Metabolism; Mitochondria; Nutrition

Indexed keywords

ADENOSINE DIPHOSPHATE; PROTEIN; REACTIVE OXYGEN METABOLITE;

EID: 65349105519     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.108.072595     Document Type: Article
Times cited : (71)

References (66)
  • 1
    • 34447498828 scopus 로고    scopus 로고
    • Integration of physiological and molecular mechanisms of the developmental origins of adult disease: New concepts and insights
    • Symonds ME. Integration of physiological and molecular mechanisms of the developmental origins of adult disease: new concepts and insights. Proc Nutr Soc 2007; 66:442-450.
    • (2007) Proc Nutr Soc , vol.66 , pp. 442-450
    • Symonds, M.E.1
  • 3
    • 0029910378 scopus 로고    scopus 로고
    • Weanling rats exposed to maternal low-protein diets during discrete periods of gestation exhibit differing severity of hypertension
    • Langley-Evans SC, Welham SJ, Sherman RC, Jackson AA. Weanling rats exposed to maternal low-protein diets during discrete periods of gestation exhibit differing severity of hypertension. Clin Sci (Lond) 1996; 91:607-615.
    • (1996) Clin Sci (Lond) , vol.91 , pp. 607-615
    • Langley-Evans, S.C.1    Welham, S.J.2    Sherman, R.C.3    Jackson, A.A.4
  • 7
    • 0033756720 scopus 로고    scopus 로고
    • Maternal undernutrition during the preimplantation period of rat developmentcauses blastocyst abnormalities and programming of postnatal hypertension
    • Kwong WY, Wild AE, Roberts P, Willis AC, Fleming TP. Maternal undernutrition during the preimplantation period of rat developmentcauses blastocyst abnormalities and programming of postnatal hypertension. Development 2000; 127:4195-4202.
    • (2000) Development , vol.127 , pp. 4195-4202
    • Kwong, W.Y.1    Wild, A.E.2    Roberts, P.3    Willis, A.C.4    Fleming, T.P.5
  • 8
    • 0034650067 scopus 로고    scopus 로고
    • Embryonic origins of health: Long-term effects of IVF in human and livestock
    • Boerjan ML, den Daas JH, Dieleman SJ. Embryonic origins of health: long-term effects of IVF in human and livestock. Theriogenology 2000; 53:537-547.
    • (2000) Theriogenology , vol.53 , pp. 537-547
    • Boerjan, M.L.1    den Daas, J.H.2    Dieleman, S.J.3
  • 9
    • 0142150076 scopus 로고    scopus 로고
    • Fetal development after assisted reproduction-a review
    • Cetin I, Cozzi V, Antonazzo P. Fetal development after assisted reproduction-a review. Placenta 2003; 24(suppl B):S104-S113.
    • (2003) Placenta , vol.24 , Issue.SUPPL. B
    • Cetin, I.1    Cozzi, V.2    Antonazzo, P.3
  • 10
    • 33646442066 scopus 로고    scopus 로고
    • Assisted reproductive technology: Both sides now
    • Cheung AP. Assisted reproductive technology: both sides now. J Reprod Med 2006; 51:283-292.
    • (2006) J Reprod Med , vol.51 , pp. 283-292
    • Cheung, A.P.1
  • 11
    • 0038060444 scopus 로고    scopus 로고
    • Safety issues in assisted reproduction technology. From theory to reality-just what are the data telling us about ICSI offspring health and future fertility and should we be concerned?
    • Kurinczuk JJ. Safety issues in assisted reproduction technology. From theory to reality-just what are the data telling us about ICSI offspring health and future fertility and should we be concerned? Hum Reprod 2003; 18:925-931.
    • (2003) Hum Reprod , vol.18 , pp. 925-931
    • Kurinczuk, J.J.1
  • 12
    • 31044437429 scopus 로고    scopus 로고
    • Perturbations in mouse embryo development and viability caused by ammonium are more severe after exposure at the cleavage stages
    • Zander DL, Thompson JG, Lane M. Perturbations in mouse embryo development and viability caused by ammonium are more severe after exposure at the cleavage stages. Biol Reprod 2006; 74:288-294.
    • (2006) Biol Reprod , vol.74 , pp. 288-294
    • Zander, D.L.1    Thompson, J.G.2    Lane, M.3
  • 13
    • 33845893558 scopus 로고    scopus 로고
    • Ovine fetal development is more sensitive to perturbation by the presence of serum in embryo culture before rather than after compaction
    • Rooke JA, McEvoy TG, Ashworth CJ, Robinson JJ, Wilmut I, Young LE, Sinclair KD. Ovine fetal development is more sensitive to perturbation by the presence of serum in embryo culture before rather than after compaction. Theriogenology 2007; 67:639-647.
    • (2007) Theriogenology , vol.67 , pp. 639-647
    • Rooke, J.A.1    McEvoy, T.G.2    Ashworth, C.J.3    Robinson, J.J.4    Wilmut, I.5    Young, L.E.6    Sinclair, K.D.7
  • 15
    • 33749245906 scopus 로고    scopus 로고
    • Zygote donor nitrogen metabolism and in vitro embryo culture perturbs in utero development and IGF2R expression in ovine fetal tissues
    • Powell K, Rooke JA, McEvoy TG, Ashworth CJ, Robinson JJ, Wilmut I, Young LE, Sinclair KD. Zygote donor nitrogen metabolism and in vitro embryo culture perturbs in utero development and IGF2R expression in ovine fetal tissues. Theriogenology 2006; 66:1901-1912.
    • (2006) Theriogenology , vol.66 , pp. 1901-1912
    • Powell, K.1    Rooke, J.A.2    McEvoy, T.G.3    Ashworth, C.J.4    Robinson, J.J.5    Wilmut, I.6    Young, L.E.7    Sinclair, K.D.8
  • 16
    • 0034297049 scopus 로고    scopus 로고
    • Nitrogen metabolism and fertility in cattle: II. Development of oocytes recovered from heifers offered diets differing in their rate of nitrogen release in the rumen
    • Sinclair KD, Kuran M, Gebbie FE, Webb R, McEvoy TG. Nitrogen metabolism and fertility in cattle: II. Development of oocytes recovered from heifers offered diets differing in their rate of nitrogen release in the rumen. J Anim Sci 2000; 78:2670-2680.
    • (2000) J Anim Sci , vol.78 , pp. 2670-2680
    • Sinclair, K.D.1    Kuran, M.2    Gebbie, F.E.3    Webb, R.4    McEvoy, T.G.5
  • 17
    • 15844383718 scopus 로고    scopus 로고
    • High-protein diet inhibits inner cell mass formation and increases apoptosis in mouse blastocysts developed in vivo by increasing the levels of ammonium in the reproductive tract
    • Gardner DK, Stilley KS, Lane M. High-protein diet inhibits inner cell mass formation and increases apoptosis in mouse blastocysts developed in vivo by increasing the levels of ammonium in the reproductive tract. Reprod Fertil Dev 2004; 16:190.
    • (2004) Reprod Fertil Dev , vol.16 , pp. 190
    • Gardner, D.K.1    Stilley, K.S.2    Lane, M.3
  • 18
    • 0031149204 scopus 로고    scopus 로고
    • Dietary excesses of urea influence the viability and metabolism of preimplantation sheep embryos and may affect fetal growth among survivors
    • McEvoy TG, Robinson JJ, Aitken RP, Findlay PA, Robertson IS. Dietary excesses of urea influence the viability and metabolism of preimplantation sheep embryos and may affect fetal growth among survivors. Anim Reprod Sci 1997; 47:71-90.
    • (1997) Anim Reprod Sci , vol.47 , pp. 71-90
    • McEvoy, T.G.1    Robinson, J.J.2    Aitken, R.P.3    Findlay, P.A.4    Robertson, I.S.5
  • 19
    • 0141683784 scopus 로고    scopus 로고
    • Ammonium induces aberrant blastocyst differentiation, metabolism, pH regulation, gene expression and subsequently alters fetal development in the mouse
    • Lane M, Gardner DK. Ammonium induces aberrant blastocyst differentiation, metabolism, pH regulation, gene expression and subsequently alters fetal development in the mouse. Biol Reprod 2003; 69:1109-1117.
    • (2003) Biol Reprod , vol.69 , pp. 1109-1117
    • Lane, M.1    Gardner, D.K.2
  • 20
    • 15844431244 scopus 로고    scopus 로고
    • Diet affects embryo imprinting and fetal development
    • Gardner DK, Hewitt E, Linck D. Diet affects embryo imprinting and fetal development. Hum Reprod 2004; 19(suppl 1):i27.
    • (2004) Hum Reprod , vol.19 , Issue.SUPPL. 1
    • Gardner, D.K.1    Hewitt, E.2    Linck, D.3
  • 21
    • 0142062965 scopus 로고    scopus 로고
    • Fetal abnormalities produced after preimplantation exposure of mouse embryos to ammonium chloride
    • Sinawat S, Hsaio WC, Flockhart JH, Kaufman MH, Keith J, West JD. Fetal abnormalities produced after preimplantation exposure of mouse embryos to ammonium chloride. Hum Reprod 2003; 18:2157-2165.
    • (2003) Hum Reprod , vol.18 , pp. 2157-2165
    • Sinawat, S.1    Hsaio, W.C.2    Flockhart, J.H.3    Kaufman, M.H.4    Keith, J.5    West, J.D.6
  • 22
    • 0032961178 scopus 로고    scopus 로고
    • The effects of maternal protein restriction on the growth of the rat fetus and its amino acid supply
    • Rees WD, Hay SM, Buchan V, Antipatis C, Palmer RM. The effects of maternal protein restriction on the growth of the rat fetus and its amino acid supply. Br J Nutr 1999; 81:243-250.
    • (1999) Br J Nutr , vol.81 , pp. 243-250
    • Rees, W.D.1    Hay, S.M.2    Buchan, V.3    Antipatis, C.4    Palmer, R.M.5
  • 23
    • 33747639310 scopus 로고    scopus 로고
    • Imprinted gene expression in the rat embryo- fetal axis is altered in response to periconceptional maternal low protein diet
    • Kwong WY, Miller DJ, Ursell E, Wild AE, Wilkins AP, Osmond C, Anthony FW, Fleming TP. Imprinted gene expression in the rat embryo- fetal axis is altered in response to periconceptional maternal low protein diet. Reproduction 2006; 132:265-277.
    • (2006) Reproduction , vol.132 , pp. 265-277
    • Kwong, W.Y.1    Miller, D.J.2    Ursell, E.3    Wild, A.E.4    Wilkins, A.P.5    Osmond, C.6    Anthony, F.W.7    Fleming, T.P.8
  • 25
    • 0030065590 scopus 로고    scopus 로고
    • What is the relationship between the metabolism of preimplantation embryos and their developmental competence?
    • Barnett DK, Bavister BD. What is the relationship between the metabolism of preimplantation embryos and their developmental competence? Mol Reprod Dev 1996; 43:105-133.
    • (1996) Mol Reprod Dev , vol.43 , pp. 105-133
    • Barnett, D.K.1    Bavister, B.D.2
  • 26
    • 59949103183 scopus 로고    scopus 로고
    • Disruption of mitochondrial malate-aspartate shuttle activity in mouse blastocysts impairs viability and fetal growth
    • Mitchell M, Cashman KS, Gardner DK, Thompson JG, Lane M. Disruption of mitochondrial malate-aspartate shuttle activity in mouse blastocysts impairs viability and fetal growth. Biol Reprod 2009; 80:295-301.
    • (2009) Biol Reprod , vol.80 , pp. 295-301
    • Mitchell, M.1    Cashman, K.S.2    Gardner, D.K.3    Thompson, J.G.4    Lane, M.5
  • 29
    • 0036181469 scopus 로고    scopus 로고
    • Domains of high- polarized and low-polarized mitochondria may occur in mouse and human oocytes and early embryos
    • Van Blerkom J, Davis P, Mathwig V, Alexander S. Domains of high- polarized and low-polarized mitochondria may occur in mouse and human oocytes and early embryos. Hum Reprod 2002; 17:393-406.
    • (2002) Hum Reprod , vol.17 , pp. 393-406
    • Van Blerkom, J.1    Davis, P.2    Mathwig, V.3    Alexander, S.4
  • 32
    • 0028158572 scopus 로고
    • Increased systolic blood pressure in adult rats induced by fetal exposure to maternal low protein diets
    • Langley SC, Jackson AA. Increased systolic blood pressure in adult rats induced by fetal exposure to maternal low protein diets. Clin Sci (Lond) 1994; 86:217-222.
    • (1994) Clin Sci (Lond) , vol.86 , pp. 217-222
    • Langley, S.C.1    Jackson, A.A.2
  • 33
    • 34547129076 scopus 로고    scopus 로고
    • Maternal exposure to dexamethasone or cortisol in early pregnancy differentially alters insulin secretion and glucose homeostasis in adult male sheep offspring
    • De Blasio MJ, Dodic M, Jefferies AJ, Moritz KM, Wintour EM, Owens JA. Maternal exposure to dexamethasone or cortisol in early pregnancy differentially alters insulin secretion and glucose homeostasis in adult male sheep offspring. Am J Physiol Endocrinol Metab 2007; 293:E75-E82.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • De Blasio, M.J.1    Dodic, M.2    Jefferies, A.J.3    Moritz, K.M.4    Wintour, E.M.5    Owens, J.A.6
  • 34
    • 26944451517 scopus 로고    scopus 로고
    • Preparation of gametes, in vitro maturation, in vitro fertilization and embryo recovery and transfer
    • Gardner DK, Lane M, Watson AJ eds, New York: Oxford University Press;
    • Lane M, Gardner DK. Preparation of gametes, in vitro maturation, in vitro fertilization and embryo recovery and transfer. In: Gardner DK, Lane M, Watson AJ (eds.), A Laboratory Guide to the Mammalian Embryo. New York: Oxford University Press; 2004:24-40.
    • (2004) A Laboratory Guide to the Mammalian Embryo , pp. 24-40
    • Lane, M.1    Gardner, D.K.2
  • 35
    • 0033780350 scopus 로고    scopus 로고
    • EDTA stimulates cleavage stage bovine embryo development in culture but inhibits blastocyst development and differentiation
    • Gardner DK, Lane MW, Lane M. EDTA stimulates cleavage stage bovine embryo development in culture but inhibits blastocyst development and differentiation. Mol Reprod Dev 2000; 57:256-261.
    • (2000) Mol Reprod Dev , vol.57 , pp. 256-261
    • Gardner, D.K.1    Lane, M.W.2    Lane, M.3
  • 36
    • 0035216832 scopus 로고    scopus 로고
    • Mitochondrial modulation of calcium signaling at the initiation of development
    • Liu L, Hammar K, Smith PJ, Inoue S, Keefe DL. Mitochondrial modulation of calcium signaling at the initiation of development. Cell Calcium 2001; 30:423-433.
    • (2001) Cell Calcium , vol.30 , pp. 423-433
    • Liu, L.1    Hammar, K.2    Smith, P.J.3    Inoue, S.4    Keefe, D.L.5
  • 37
    • 0035110347 scopus 로고    scopus 로고
    • Mitochondrial distribution and adenosine triphosphate content of bovine oocytes before and after in vitro maturation: Correlation with morphological criteria and developmental capacity after in vitro fertilization and culture
    • Stojkovic M, Machado SA, Stojkovic P, Zakhartchenko V, Hutzler P, Goncalves PB, Wolf E. Mitochondrial distribution and adenosine triphosphate content of bovine oocytes before and after in vitro maturation: correlation with morphological criteria and developmental capacity after in vitro fertilization and culture. Biol Reprod 2001; 64:904-909.
    • (2001) Biol Reprod , vol.64 , pp. 904-909
    • Stojkovic, M.1    Machado, S.A.2    Stojkovic, P.3    Zakhartchenko, V.4    Hutzler, P.5    Goncalves, P.B.6    Wolf, E.7
  • 38
    • 0030869334 scopus 로고    scopus 로고
    • Glucose and phosphate toxicity in hamster preimplantation embryos involves disruption of cellular organization, including distribution of active mitochondria
    • Barnett DK, Clayton MK, Kimura J, Bavister BD. Glucose and phosphate toxicity in hamster preimplantation embryos involves disruption of cellular organization, including distribution of active mitochondria. Mol Reprod Dev 1997; 48:227-237.
    • (1997) Mol Reprod Dev , vol.48 , pp. 227-237
    • Barnett, D.K.1    Clayton, M.K.2    Kimura, J.3    Bavister, B.D.4
  • 40
    • 0021228061 scopus 로고
    • Nucleotides in a single mammalian ovum or preimplantation embryo
    • Leese HJ, Biggers JD, Mroz EA, Lechene C. Nucleotides in a single mammalian ovum or preimplantation embryo. Anal Biochem 1984; 140: 443-448.
    • (1984) Anal Biochem , vol.140 , pp. 443-448
    • Leese, H.J.1    Biggers, J.D.2    Mroz, E.A.3    Lechene, C.4
  • 41
    • 0021264454 scopus 로고
    • Pyruvate and glucose uptake by mouse ova and preimplantation embryos
    • Leese HJ, Barton AM. Pyruvate and glucose uptake by mouse ova and preimplantation embryos. J Reprod Fertil 1984; 72:9-13.
    • (1984) J Reprod Fertil , vol.72 , pp. 9-13
    • Leese, H.J.1    Barton, A.M.2
  • 42
    • 0025364518 scopus 로고
    • Hydrogen peroxide levels in mouse oocytes and early cleavage stage embryos developed in vitro or in vivo
    • Nasr-Esfahani MH, Aitken JR, Johnson MH. Hydrogen peroxide levels in mouse oocytes and early cleavage stage embryos developed in vitro or in vivo. Development 1990; 109:501-507.
    • (1990) Development , vol.109 , pp. 501-507
    • Nasr-Esfahani, M.H.1    Aitken, J.R.2    Johnson, M.H.3
  • 43
  • 44
    • 9744255470 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in mouse oocytes results in preimplantation embryo arrest in vitro
    • Thouas GA, Trounson AO, Wolvetang EJ, Jones GM. Mitochondrial dysfunction in mouse oocytes results in preimplantation embryo arrest in vitro. Biol Reprod 2004; 71:1936-1942.
    • (2004) Biol Reprod , vol.71 , pp. 1936-1942
    • Thouas, G.A.1    Trounson, A.O.2    Wolvetang, E.J.3    Jones, G.M.4
  • 46
    • 0842328798 scopus 로고    scopus 로고
    • Roles of mitochondria in health and disease
    • Duchen MR. Roles of mitochondria in health and disease. Diabetes 2004; 53(suppl 1):S96-S102.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Duchen, M.R.1
  • 48
    • 0025319665 scopus 로고
    • Role of calcium ions in regulation of mammalian intramitochondrial metabolism
    • McCormack JG, Halestrap AP, Denton RM. Role of calcium ions in regulation of mammalian intramitochondrial metabolism. Physiol Rev 1990; 70:391-425.
    • (1990) Physiol Rev , vol.70 , pp. 391-425
    • McCormack, J.G.1    Halestrap, A.P.2    Denton, R.M.3
  • 50
    • 1042292033 scopus 로고    scopus 로고
    • Alterations in mito- chondrial membrane potential during preimplantation stages of mouse and human embryo development
    • Acton BM, Jurisicova A, Jurisica I, Casper RF. Alterations in mito- chondrial membrane potential during preimplantation stages of mouse and human embryo development. Mol Hum Reprod 2004; 10:23-32.
    • (2004) Mol Hum Reprod , vol.10 , pp. 23-32
    • Acton, B.M.1    Jurisicova, A.2    Jurisica, I.3    Casper, R.F.4
  • 51
    • 4544353776 scopus 로고    scopus 로고
    • Mitochondria in human oogenesis and preimplantation embryogenesis: Engines of metabolism, ionic regulation and developmental competence
    • Van Blerkom J. Mitochondria in human oogenesis and preimplantation embryogenesis: engines of metabolism, ionic regulation and developmental competence. Reproduction 2004; 128:269-280.
    • (2004) Reproduction , vol.128 , pp. 269-280
    • Van Blerkom, J.1
  • 53
    • 33646014776 scopus 로고    scopus 로고
    • Developmental effects of sublethal mitochondrial injury in mouse oocytes
    • Thouas GA, Trounson AO, Jones GM. Developmental effects of sublethal mitochondrial injury in mouse oocytes. Biol Reprod 2006; 74:969-977.
    • (2006) Biol Reprod , vol.74 , pp. 969-977
    • Thouas, G.A.1    Trounson, A.O.2    Jones, G.M.3
  • 54
    • 33750475625 scopus 로고    scopus 로고
    • Free radicals, mitochondria, and oxidized lipids: The emerging role in signal transduction in vascular cells
    • Gutierrez J, Ballinger SW, Darley-Usmar VM, Landar A. Free radicals, mitochondria, and oxidized lipids: the emerging role in signal transduction in vascular cells. Circ Res 2006; 99:924-932.
    • (2006) Circ Res , vol.99 , pp. 924-932
    • Gutierrez, J.1    Ballinger, S.W.2    Darley-Usmar, V.M.3    Landar, A.4
  • 55
    • 33847359190 scopus 로고    scopus 로고
    • Regulation of redox metabolism in the mouse oocyte and embryo
    • Dumollard R, Ward Z, Carroll J, Duchen MR. Regulation of redox metabolism in the mouse oocyte and embryo. Development 2007; 134: 455-465.
    • (2007) Development , vol.134 , pp. 455-465
    • Dumollard, R.1    Ward, Z.2    Carroll, J.3    Duchen, M.R.4
  • 56
    • 0036714938 scopus 로고    scopus 로고
    • Quiet please, do not disturb: A hypothesis of embryo metabolism and viability
    • Leese HJ. Quiet please, do not disturb: a hypothesis of embryo metabolism and viability. Bioessays 2002; 24:845-849.
    • (2002) Bioessays , vol.24 , pp. 845-849
    • Leese, H.J.1
  • 57
    • 0027977128 scopus 로고
    • Radical solutions and cultural problems: Could free oxygen radicals be responsible for the impaired development of preimplantation mammalian embryos in vitro?
    • Johnson MH, Nasr-Esfahani MH. Radical solutions and cultural problems: could free oxygen radicals be responsible for the impaired development of preimplantation mammalian embryos in vitro? Bioessays 1994; 16:31-38.
    • (1994) Bioessays , vol.16 , pp. 31-38
    • Johnson, M.H.1    Nasr-Esfahani, M.H.2
  • 58
    • 38949197461 scopus 로고    scopus 로고
    • Maternal supply of omega-3 polyunsaturated fatty acids alter mechanisms involved in oocyte and early embryo development in the mouse
    • Wakefield SL, Lane M, Schulz SJ, Hebart ML, Thompson JG, Mitchell M. Maternal supply of omega-3 polyunsaturated fatty acids alter mechanisms involved in oocyte and early embryo development in the mouse. Am J Physiol Endocrinol Metab 2008; 294:E425-E434.
    • (2008) Am J Physiol Endocrinol Metab , vol.294
    • Wakefield, S.L.1    Lane, M.2    Schulz, S.J.3    Hebart, M.L.4    Thompson, J.G.5    Mitchell, M.6
  • 59
    • 33751159208 scopus 로고    scopus 로고
    • Development to the blastocyst stage, the oxidative state, and the quality of early developmental stage of porcine embryos cultured in alteration of glucose concentrations in vitro under different oxygen tensions
    • Karja NW, Kikuchi K, Fahrudin M, Ozawa M, Somfai T, Ohnuma K, Noguchi J, Kaneko H, Nagai T. Development to the blastocyst stage, the oxidative state, and the quality of early developmental stage of porcine embryos cultured in alteration of glucose concentrations in vitro under different oxygen tensions. Reprod Biol Endocrinol 2006; 4:54-65.
    • (2006) Reprod Biol Endocrinol , vol.4 , pp. 54-65
    • Karja, N.W.1    Kikuchi, K.2    Fahrudin, M.3    Ozawa, M.4    Somfai, T.5    Ohnuma, K.6    Noguchi, J.7    Kaneko, H.8    Nagai, T.9
  • 60
    • 4544280654 scopus 로고    scopus 로고
    • Mitochondria and aging: A role for the permeability transition?
    • Crompton M. Mitochondria and aging: a role for the permeability transition? Aging Cell 2004; 3:3-6.
    • (2004) Aging Cell , vol.3 , pp. 3-6
    • Crompton, M.1
  • 61
    • 0030868479 scopus 로고    scopus 로고
    • The mitochondrial permeability transition in toxic, hypoxic and reperfusion injury
    • Lemasters JJ, Nieminen AL, Qian T, Trost LC, Herman B. The mitochondrial permeability transition in toxic, hypoxic and reperfusion injury. Mol Cell Biochem 1997; 174:159-165.
    • (1997) Mol Cell Biochem , vol.174 , pp. 159-165
    • Lemasters, J.J.1    Nieminen, A.L.2    Qian, T.3    Trost, L.C.4    Herman, B.5
  • 62
    • 5444229139 scopus 로고    scopus 로고
    • Mitochondrial uncoupling as a potential therapeutic target in acute central nervous system injury
    • Maragos WF, Korde AS. Mitochondrial uncoupling as a potential therapeutic target in acute central nervous system injury. J Neurochem 2004; 91:257-262.
    • (2004) J Neurochem , vol.91 , pp. 257-262
    • Maragos, W.F.1    Korde, A.S.2
  • 63
    • 0031008145 scopus 로고    scopus 로고
    • Role of the mitochondrial permeability transition pore in apoptosis
    • Hirsch T, Marzo I, Kroemer G. Role of the mitochondrial permeability transition pore in apoptosis. Biosci Rep 1997; 17:67-76.
    • (1997) Biosci Rep , vol.17 , pp. 67-76
    • Hirsch, T.1    Marzo, I.2    Kroemer, G.3
  • 65
    • 0030026216 scopus 로고    scopus 로고
    • Translocation of active mitochondria during hamster preimplantation embryo development studied by confocal laser scanning microscopy
    • Barnett DK, Kimura J, Bavister BD. Translocation of active mitochondria during hamster preimplantation embryo development studied by confocal laser scanning microscopy. Dev Dyn 1996; 205:64-72.
    • (1996) Dev Dyn , vol.205 , pp. 64-72
    • Barnett, D.K.1    Kimura, J.2    Bavister, B.D.3
  • 66
    • 0031657530 scopus 로고    scopus 로고
    • Calcium homeostasis in early hamster preimplantation embryos
    • Lane M, Bavister BD. Calcium homeostasis in early hamster preimplantation embryos. Biol Reprod 1998; 59:1000-1007.
    • (1998) Biol Reprod , vol.59 , pp. 1000-1007
    • Lane, M.1    Bavister, B.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.