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Volumn 27, Issue 1, 2009, Pages 11-16

Phase II study of arsenic trioxide and ascorbic acid for relapsed or refractory lymphoid malignancies: A Wisconsin Oncology Network study

Author keywords

Arsenic trioxide; Ascorbic acid; Lymphoma

Indexed keywords

ARSENIC TRIOXIDE; ASCORBIC ACID; GLUTATHIONE; PROTEIN BAX; PROTEIN BCL 2; ORGANOARSENIC DERIVATIVE; OXIDE;

EID: 65249172078     PISSN: 02780232     EISSN: 10991069     Source Type: Journal    
DOI: 10.1002/hon.870     Document Type: Article
Times cited : (28)

References (45)
  • 1
    • 0001837016 scopus 로고    scopus 로고
    • Arsenic trioxide treated 72 cases of acute promyelocytic leukemia
    • Zhang P, Wang SY, Hu XH. Arsenic trioxide treated 72 cases of acute promyelocytic leukemia. Chin J Hematol 1996; 17: 58-72.
    • (1996) Chin J Hematol , vol.17 , pp. 58-72
    • Zhang, P.1    Wang, S.Y.2    Hu, X.H.3
  • 2
    • 0030610687 scopus 로고    scopus 로고
    • Use of arsenic trioxide in the treatment of acute promyelocytic leukemia (APL): Clinical efficacy and pharmacokinetics in relapsed patients
    • Shen ZX, Chen GQ, Ni JH, et al. Use of arsenic trioxide in the treatment of acute promyelocytic leukemia (APL): clinical efficacy and pharmacokinetics in relapsed patients. Blood 1997; 89: 3354-3360.
    • (1997) Blood , vol.89 , pp. 3354-3360
    • Shen, Z.X.1    Chen, G.Q.2    Ni, J.H.3
  • 3
    • 0033570955 scopus 로고    scopus 로고
    • Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: Remission induction, follow-up, and molecular monitoring in 11 newly diagnosed and 47 relapsed acute promyelocytic leukemia patients
    • Niu C, Yan H, Yu T, et al. Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: remission induction, follow-up, and molecular monitoring in 11 newly diagnosed and 47 relapsed acute promyelocytic leukemia patients. Blood 1999; 94: 3315-3324.
    • (1999) Blood , vol.94 , pp. 3315-3324
    • Niu, C.1    Yan, H.2    Yu, T.3
  • 4
    • 0032487923 scopus 로고    scopus 로고
    • Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide
    • Soignet SL, Maslak P, Wang ZG, et al. Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide. N Engl J Med 1998; 339: 1341-1348.
    • (1998) N Engl J Med , vol.339 , pp. 1341-1348
    • Soignet, S.L.1    Maslak, P.2    Wang, Z.G.3
  • 5
    • 33745002275 scopus 로고    scopus 로고
    • Phase II multicenter study of arsenic trioxide in patients with myelodysplastic syndromes
    • Schiller GJ, Slack J, Hainsworth JD, et al. Phase II multicenter study of arsenic trioxide in patients with myelodysplastic syndromes. J Clin Oncol 2006; 24: 2456-2464.
    • (2006) J Clin Oncol , vol.24 , pp. 2456-2464
    • Schiller, G.J.1    Slack, J.2    Hainsworth, J.D.3
  • 6
    • 33744966168 scopus 로고    scopus 로고
    • Arsenic trioxide in patients with myelodysplastic syndromes: A phase II multicenter study
    • Vey N, Bosly A, Guerci A, et al. Arsenic trioxide in patients with myelodysplastic syndromes: a phase II multicenter study. J Clin Oncol 2006; 24: 2465-2471.
    • (2006) J Clin Oncol , vol.24 , pp. 2465-2471
    • Vey, N.1    Bosly, A.2    Guerci, A.3
  • 7
    • 0001491641 scopus 로고    scopus 로고
    • Major hematologic response in a patient with myelodysplasia to arsenic trioxide
    • Dutcher JP, Wiernik PH, Garl S. Major hematologic response in a patient with myelodysplasia to arsenic trioxide. Blood 2000; 96: 260b.
    • (2000) Blood , vol.96
    • Dutcher, J.P.1    Wiernik, P.H.2    Garl, S.3
  • 8
    • 0036739745 scopus 로고    scopus 로고
    • Clinical activity of arsenic trioxide for the treatment of multiple myeloma
    • Munshi NC, Tricot G, Desikan R, et al. Clinical activity of arsenic trioxide for the treatment of multiple myeloma. Leukemia 2002; 16: 1835-1837.
    • (2002) Leukemia , vol.16 , pp. 1835-1837
    • Munshi, N.C.1    Tricot, G.2    Desikan, R.3
  • 9
    • 0035030143 scopus 로고    scopus 로고
    • Arsenic trioxide: An emerging therapy for multiple myeloma
    • Munshi NC. Arsenic trioxide: an emerging therapy for multiple myeloma. Oncologist 2001; 6 (Suppl 2): 17-21.
    • (2001) Oncologist , vol.6 , Issue.SUPPL. 2 , pp. 17-21
    • Munshi, N.C.1
  • 10
    • 0003274705 scopus 로고    scopus 로고
    • 3) in high risk refractory multiple myeloma
    • 3) in high risk refractory multiple myeloma. Blood 1999; 94 (Suppl 1): 123a.
    • (1999) Blood , vol.94 , Issue.SUPPL. 1
    • Munshi, N.C.1    Desikan, R.2    Zangari, M.3
  • 11
    • 3142715479 scopus 로고    scopus 로고
    • Phase 2 study of arsenic trioxide in patients with relapsed or refractory multiple myeloma
    • Hussein MA, Saleh M, Ravandi F, et al. Phase 2 study of arsenic trioxide in patients with relapsed or refractory multiple myeloma. Br J Haematol 2004; 125: 470-476.
    • (2004) Br J Haematol , vol.125 , pp. 470-476
    • Hussein, M.A.1    Saleh, M.2    Ravandi, F.3
  • 12
    • 0031708772 scopus 로고    scopus 로고
    • The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms
    • Zhang W, Ohnishi K, Shigeno K, et al. The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms. Leukemia 1998; 12: 1383-1391.
    • (1998) Leukemia , vol.12 , pp. 1383-1391
    • Zhang, W.1    Ohnishi, K.2    Shigeno, K.3
  • 13
    • 0033526358 scopus 로고    scopus 로고
    • Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations
    • Zhu XH, Shen YL, Jing YK, et al. Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations. J Natl Cancer Inst 1999; 91: 772-778.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 772-778
    • Zhu, X.H.1    Shen, Y.L.2    Jing, Y.K.3
  • 14
    • 0038125071 scopus 로고    scopus 로고
    • Comparative activity of melarsoprol and arsenic trioxide in chronic B-cell leukemia lines
    • König A, Wrazel L, Warrell RP, et al. Comparative activity of melarsoprol and arsenic trioxide in chronic B-cell leukemia lines. Blood 1997; 90: 562-570.
    • (1997) Blood , vol.90 , pp. 562-570
    • König, A.1    Wrazel, L.2    Warrell, R.P.3
  • 15
    • 0031691443 scopus 로고    scopus 로고
    • Arsenic induces apoptosis in B-cell leukaemic cell lines in vitro: Activation of capsases and down-regulation of Bcl-2 protein
    • Akao Y, Mizoguchi H, Kojima S, et al. Arsenic induces apoptosis in B-cell leukaemic cell lines in vitro: activation of capsases and down-regulation of Bcl-2 protein. Br J Haematol 1998; 102: 1055-1062.
    • (1998) Br J Haematol , vol.102 , pp. 1055-1062
    • Akao, Y.1    Mizoguchi, H.2    Kojima, S.3
  • 16
    • 0037269294 scopus 로고    scopus 로고
    • Clinical activity of arsenic trioxide in Burkitt-like lymphoma
    • Ranvandi F, van Besien K. Clinical activity of arsenic trioxide in Burkitt-like lymphoma. Leukemia 2003; 17: 271-272.
    • (2003) Leukemia , vol.17 , pp. 271-272
    • Ranvandi, F.1    van Besien, K.2
  • 17
    • 0030610686 scopus 로고    scopus 로고
    • 3 exerts dose-dependent dual effects on APL cells
    • 3 exerts dose-dependent dual effects on APL cells. Blood 1997; 89: 3345-3353.
    • (1997) Blood , vol.89 , pp. 3345-3353
    • Chen, G.Q.1    Shi, X.G.2    Tang, W.3
  • 18
    • 0035041127 scopus 로고    scopus 로고
    • Clinical trials of arsenic trioxide in hematologic and solid tumors: Overview of the National Cancer Institute Cooperative Research and Development studies
    • Murgo AJ. Clinical trials of arsenic trioxide in hematologic and solid tumors: overview of the National Cancer Institute Cooperative Research and Development studies. Oncologist 2001; 6 (Suppl 2): 22-28.
    • (2001) Oncologist , vol.6 , Issue.SUPPL. 2 , pp. 22-28
    • Murgo, A.J.1
  • 19
    • 0033568238 scopus 로고    scopus 로고
    • Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway
    • Jing Y, Dai J, Chalmers-Redman R, Tatton WG, Waxman S. Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway. Blood 1999; 94: 2102-2111.
    • (1999) Blood , vol.94 , pp. 2102-2111
    • Jing, Y.1    Dai, J.2    Chalmers-Redman, R.3    Tatton, W.G.4    Waxman, S.5
  • 20
    • 0032933610 scopus 로고    scopus 로고
    • Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox systems
    • Dai J, Weinberg RS, Waxman S, Jing Y. Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox systems. Blood 1999; 93: 268-277.
    • (1999) Blood , vol.93 , pp. 268-277
    • Dai, J.1    Weinberg, R.S.2    Waxman, S.3    Jing, Y.4
  • 21
    • 0032718622 scopus 로고    scopus 로고
    • Arsenic trioxide sensitivity is associated with low level of glutathione in cancer cells
    • Yang CH, Kuo ML, Chen JC, Chen YC. Arsenic trioxide sensitivity is associated with low level of glutathione in cancer cells. Br J Cancer 1999; 81: 796-799.
    • (1999) Br J Cancer , vol.81 , pp. 796-799
    • Yang, C.H.1    Kuo, M.L.2    Chen, J.C.3    Chen, Y.C.4
  • 22
    • 0035437189 scopus 로고    scopus 로고
    • Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells
    • Grad JM, Bahlis NJ, Reis I, et al. Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells. Blood 2001; 98: 805-813.
    • (2001) Blood , vol.98 , pp. 805-813
    • Grad, J.M.1    Bahlis, N.J.2    Reis, I.3
  • 23
    • 0036965488 scopus 로고    scopus 로고
    • Effects of ascorbic acid and alpha-tocopherol on arsenic-induced oxidative stress
    • Ramanathan K, Balakumar BS, Panneerselvam C. Effects of ascorbic acid and alpha-tocopherol on arsenic-induced oxidative stress. Hum Exp Toxicol 2002; 21: 675-680.
    • (2002) Hum Exp Toxicol , vol.21 , pp. 675-680
    • Ramanathan, K.1    Balakumar, B.S.2    Panneerselvam, C.3
  • 24
    • 0041706213 scopus 로고    scopus 로고
    • Ascorbic acid and alpha-tocopherol as potent modulators on arsenic induced toxicity in mitochondria
    • Ramanathan K, Shila S, Kumaran S, Panneerselvam C. Ascorbic acid and alpha-tocopherol as potent modulators on arsenic induced toxicity in mitochondria. J Nutr Biochem 2003; 14: 416-420.
    • (2003) J Nutr Biochem , vol.14 , pp. 416-420
    • Ramanathan, K.1    Shila, S.2    Kumaran, S.3    Panneerselvam, C.4
  • 25
    • 0035107590 scopus 로고    scopus 로고
    • Arsenic trioxide and ascorbic acid: Synergy with potential implications for the treatment of acute myeloid leukemia
    • Bachleitner-Hofmann T, Gisslinger B, Grumbeck E, Gisslinger H. Arsenic trioxide and ascorbic acid: synergy with potential implications for the treatment of acute myeloid leukemia. Br J Haematol 2001; 112: 783-786.
    • (2001) Br J Haematol , vol.112 , pp. 783-786
    • Bachleitner-Hofmann, T.1    Gisslinger, B.2    Grumbeck, E.3    Gisslinger, H.4
  • 26
    • 0042449063 scopus 로고    scopus 로고
    • Report of an international workshop to standardize response criteria for nonHodgkin lymphomas: NCI Sponsored International Working Group
    • Cheson BD, Horning SJ, Coiffier B, et al. Report of an international workshop to standardize response criteria for nonHodgkin lymphomas: NCI Sponsored International Working Group. J Clin Oncol 1999; 17: 1244-1253.
    • (1999) J Clin Oncol , vol.17 , pp. 1244-1253
    • Cheson, B.D.1    Horning, S.J.2    Coiffier, B.3
  • 27
    • 0029981025 scopus 로고    scopus 로고
    • National Cancer Institute-sponsored Working Groups guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
    • Cheson BD, Bennett JM, Grever M, et al. National Cancer Institute-sponsored Working Groups guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood 1996; 87: 4990-4997.
    • (1996) Blood , vol.87 , pp. 4990-4997
    • Cheson, B.D.1    Bennett, J.M.2    Grever, M.3
  • 28
    • 0014481378 scopus 로고
    • Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
    • Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 1969; 27: 502-522.
    • (1969) Anal Biochem , vol.27 , pp. 502-522
    • Tietze, F.1
  • 29
    • 0027444652 scopus 로고
    • A predictive model for aggressive non-Hodgkin lymphoma. The International Non-Hodgkin's Lymphoma Prognostic Factors Project
    • A predictive model for aggressive non-Hodgkin lymphoma. The International Non-Hodgkin's Lymphoma Prognostic Factors Project. N Engl J Med 1993; 329: 987-994.
    • (1993) N Engl J Med , vol.329 , pp. 987-994
  • 30
    • 0037403916 scopus 로고    scopus 로고
    • 3) in the treatment of patients with acute promyelocytic leukemia: The M.D. Anderson experience
    • 3) in the treatment of patients with acute promyelocytic leukemia: the M.D. Anderson experience. Cancer 2003; 97: 2218-2224.
    • (2003) Cancer , vol.97 , pp. 2218-2224
    • Lazo, G.1    Kantarjian, H.2    Estey, E.3
  • 31
    • 33645498328 scopus 로고    scopus 로고
    • Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: Durable remissions with minimal toxicity
    • Mathews V, George B, Lakshmi KM, et al. Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: durable remissions with minimal toxicity. Blood 2006; 107: 2627-2632.
    • (2006) Blood , vol.107 , pp. 2627-2632
    • Mathews, V.1    George, B.2    Lakshmi, K.M.3
  • 32
    • 33748755948 scopus 로고    scopus 로고
    • Efficacy and safety of melphalan, arsenic trioxide, and ascorbic acid combination therapy in patients with relapsed or refractory multiple myeloma: A prospective, multicentre, phase II, single-arm study
    • Berenson JR, Boccia R, Siegel D, et al. Efficacy and safety of melphalan, arsenic trioxide, and ascorbic acid combination therapy in patients with relapsed or refractory multiple myeloma: a prospective, multicentre, phase II, single-arm study. Br J Haematol 2006; 135: 174-183.
    • (2006) Br J Haematol , vol.135 , pp. 174-183
    • Berenson, J.R.1    Boccia, R.2    Siegel, D.3
  • 33
    • 33646884415 scopus 로고    scopus 로고
    • Efficacy and safety results with the combination therapy of arsenic trioxide, dexamethasone, and ascorbic acid in multiple myeloma patients: A phase 2 trial
    • Abou-Jawde RM, Reed J, Kelly M, et al. Efficacy and safety results with the combination therapy of arsenic trioxide, dexamethasone, and ascorbic acid in multiple myeloma patients: a phase 2 trial. Med Oncol 2006; 23: 263-272.
    • (2006) Med Oncol , vol.23 , pp. 263-272
    • Abou-Jawde, R.M.1    Reed, J.2    Kelly, M.3
  • 35
    • 0010740572 scopus 로고    scopus 로고
    • 3 induces NB-4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RARα/PML proteins
    • 3 induces NB-4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RARα/PML proteins. Blood 1996; 88: 1052-1061.
    • (1996) Blood , vol.88 , pp. 1052-1061
    • Chen, G.Q.1    Zhu, J.2    Shi, X.G.3
  • 36
    • 30844434848 scopus 로고    scopus 로고
    • Increased cellular glutathione and protection by bone marrow stromal cells account for the resistance of non-acute promylocytic leukemia acute myeloid leukemia cells to arsenic trioxide in vivo
    • Lee C, Lin Y, Huang M, et al. Increased cellular glutathione and protection by bone marrow stromal cells account for the resistance of non-acute promylocytic leukemia acute myeloid leukemia cells to arsenic trioxide in vivo. Leuk Lymphoma 2006; 47: 521-529.
    • (2006) Leuk Lymphoma , vol.47 , pp. 521-529
    • Lee, C.1    Lin, Y.2    Huang, M.3
  • 37
    • 0028157817 scopus 로고
    • Phase I clinical trial of intravenous L-buthionine sulfoximine and melphalan: An attempt at modulation of glutathione
    • Bailey HH, Mulcahy RT, Tutsch KD, et al. Phase I clinical trial of intravenous L-buthionine sulfoximine and melphalan: an attempt at modulation of glutathione. J. Clin Oncol 1994; 12: 194-205.
    • (1994) J. Clin Oncol , vol.12 , pp. 194-205
    • Bailey, H.H.1    Mulcahy, R.T.2    Tutsch, K.D.3
  • 39
    • 0028273316 scopus 로고
    • Glutathione, ascorbate, and cellular protection
    • Meister A. Glutathione, ascorbate, and cellular protection. Cancer Res 1994; 54 (Suppl 7): 1969-1975.
    • (1994) Cancer Res , vol.54 , Issue.SUPPL. 7 , pp. 1969-1975
    • Meister, A.1
  • 40
    • 11444250327 scopus 로고    scopus 로고
    • Arsenic trioxide therapy in acute promyelocytic leukemia and beyond: From bench to bedside
    • Rojewski MT, Körper S, Schrezenmeier H. Arsenic trioxide therapy in acute promyelocytic leukemia and beyond: from bench to bedside. Leuk Lymphoma 2004; 45: 2387-2401.
    • (2004) Leuk Lymphoma , vol.45 , pp. 2387-2401
    • Rojewski, M.T.1    Körper, S.2    Schrezenmeier, H.3
  • 41
    • 0036896388 scopus 로고    scopus 로고
    • Feasibility and correlates of arsenic trioxide combined with ascorbic acid-mediated depletion of intracellular glutathione for the treatment of relapsed/ refractory multiple myeloma
    • Bahlis NJ, McCafferty-Grad J, Jordan-McMurry I, et al. Feasibility and correlates of arsenic trioxide combined with ascorbic acid-mediated depletion of intracellular glutathione for the treatment of relapsed/ refractory multiple myeloma. Clin Cancer Res 2002; 8: 3658-3668.
    • (2002) Clin Cancer Res , vol.8 , pp. 3658-3668
    • Bahlis, N.J.1    McCafferty-Grad, J.2    Jordan-McMurry, I.3
  • 42
    • 0042744800 scopus 로고    scopus 로고
    • Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis
    • Mathas S, Lietz A, Janz M, et al. Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis. Blood 2003; 102: 1028-1034.
    • (2003) Blood , vol.102 , pp. 1028-1034
    • Mathas, S.1    Lietz, A.2    Janz, M.3
  • 44
    • 33745219500 scopus 로고    scopus 로고
    • Southwest Oncology Group phase II study of arsenic trioxide in patients with refractory germ cell malignancies
    • Beer TM, Tangen CM, Nichols CR, et al. Southwest Oncology Group phase II study of arsenic trioxide in patients with refractory germ cell malignancies. Cancer 2006; 106: 2624-2629.
    • (2006) Cancer , vol.106 , pp. 2624-2629
    • Beer, T.M.1    Tangen, C.M.2    Nichols, C.R.3
  • 45
    • 33746979218 scopus 로고    scopus 로고
    • A phase II trial of arsenic trioxide for relapsed and refractory acute lymphoblastic leukemia
    • Litzow MR, Lee S, Bennett JM, et al. A phase II trial of arsenic trioxide for relapsed and refractory acute lymphoblastic leukemia. Haematologica 2006; 91: 1105-1108.
    • (2006) Haematologica , vol.91 , pp. 1105-1108
    • Litzow, M.R.1    Lee, S.2    Bennett, J.M.3


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