메뉴 건너뛰기




Volumn 8, Issue 3, 2009, Pages 1515-1526

Transcription factor TBX1 overexpression induces downregulation of proteins involved in retinoic acid metabolism: A comparative proteomic analysis

Author keywords

DIGE; DiGeorge syndrome; Proteomics; Retinoic acid; T box containing transcription factor

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; CYCLIN DEPENDENT KINASE 4; CYCLINE; DJ 1 PROTEIN; GLYCINE HYDROXYMETHYLTRANSFERASE; GLYCINE HYDROXYMETHYLTRANSFERASE 2; GUANINE NUCLEOTIDE BINDING PROTEIN BETA 2; GUANINE NUCLEOTIDE BINDING PROTEIN BETA 3; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; HEAT SHOCK PROTEIN 90; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN F; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H1; KARYOPHERIN ALPHA; KARYOPHERIN ALPHA 2; NEUROLYSIN; NUCLEOLIN; NUCLEOPHOSMIN; ORNITHINE OXOACID AMINOTRANSFERASE; PEROXIREDOXIN 1; PYRUVATE KINASE; RETINOIC ACID; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TBX1; TRANSKETOLASE; UNCLASSIFIED DRUG; VILLIN; VILLIN 2; VINCULIN; VOLTAGE DEPENDENT ANION CHANNEL 1;

EID: 65249151895     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr800870d     Document Type: Article
Times cited : (25)

References (43)
  • 1
    • 0030589712 scopus 로고    scopus 로고
    • Tbx6, a mouse T-box gene implicated in paraxial mesoderm formation at gastrulation
    • Chapman, D. L.; Agulnik, I.; Hancock, S.; Silver, L. M.; Papaioan- nou, V. E. Tbx6, a mouse T-box gene implicated in paraxial mesoderm formation at gastrulation. Dev. Biol. 1996, 180, 534-542.
    • (1996) Dev. Biol , vol.180 , pp. 534-542
    • Chapman, D.L.1    Agulnik, I.2    Hancock, S.3    Silver, L.M.4    Papaioan- nou, V.E.5
  • 2
    • 0033753819 scopus 로고    scopus 로고
    • The 22q11 deletion syndromes
    • Scambler, P J. The 22q11 deletion syndromes. Hum. Mol. Genet. 2000, 9, 2421-6.
    • (2000) Hum. Mol. Genet , vol.9 , pp. 2421-2426
    • Scambler, P.J.1
  • 5
    • 0035870854 scopus 로고    scopus 로고
    • Recovery from arterial growth delay reduces penetrance of cardiovascular defects in mice deleted for the DiGeorge syndrome region
    • Lindsay, E. A.; Baldini, A. Recovery from arterial growth delay reduces penetrance of cardiovascular defects in mice deleted for the DiGeorge syndrome region. Hum. Mol. Genet. 2001, 10, 997-1002.
    • (2001) Hum. Mol. Genet , vol.10 , pp. 997-1002
    • Lindsay, E.A.1    Baldini, A.2
  • 6
    • 0037091009 scopus 로고    scopus 로고
    • Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways
    • Vitelli, F.; Morishima, M.; Taddei, I.; Lindsay, E. A.; Baldini, A. Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways. Hum. Mol. Genet. 2002, 11, 915-22.
    • (2002) Hum. Mol. Genet , vol.11 , pp. 915-922
    • Vitelli, F.1    Morishima, M.2    Taddei, I.3    Lindsay, E.A.4    Baldini, A.5
  • 7
    • 0037329890 scopus 로고    scopus 로고
    • VEGF: A modifier of the del22q11 (DiGeorge) syndrome?
    • Stalmans, I.; et al. VEGF: a modifier of the del22q11 (DiGeorge) syndrome? Nat. Med. 2003, 9, 173-82.
    • (2003) Nat. Med , vol.9 , pp. 173-182
    • Stalmans, I.1
  • 8
    • 0035098557 scopus 로고    scopus 로고
    • DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1
    • Jerome, L. A.; Papaioannou, V. E. DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1. Nat. Genet. 2001, 3, 286-91.
    • (2001) Nat. Genet , vol.3 , pp. 286-291
    • Jerome, L.A.1    Papaioannou, V.E.2
  • 9
    • 0034963495 scopus 로고    scopus 로고
    • Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development
    • Garg, V.; Yamagishi, C.; Hu, T.; Kathiriya, I. S.; Yamagishi, H.; Srivastava, D. Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development. Dev. Biol. 2001, 235, 62-73.
    • (2001) Dev. Biol , vol.235 , pp. 62-73
    • Garg, V.1    Yamagishi, C.2    Hu, T.3    Kathiriya, I.S.4    Yamagishi, H.5    Srivastava, D.6
  • 12
    • 33750282189 scopus 로고    scopus 로고
    • Mesodermal expression o Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development
    • Zhang, Z.; Huynh, T.; Baldini, A. Mesodermal expression o Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development. Development 2006, 133, 3587-3595.
    • (2006) Development , vol.133 , pp. 3587-3595
    • Zhang, Z.1    Huynh, T.2    Baldini, A.3
  • 13
    • 33745197499 scopus 로고    scopus 로고
    • Tissue specific roles of Tbx1 in the development of the outer, middle and inner ear, defective in 22q11DS
    • Arnold, J. S.; Braunstein, E. M.; Ohyama, T.; Groves, A. K.; Adams, J. C.; Brown, M. C.; Morrow, B. E. Tissue specific roles of Tbx1 in the development of the outer, middle and inner ear, defective in 22q11DS. Hum. Mol. Genet. 2006, 15, 1629-3.
    • (2006) Hum. Mol. Genet , vol.15 , pp. 1629-1633
    • Arnold, J.S.1    Braunstein, E.M.2    Ohyama, T.3    Groves, A.K.4    Adams, J.C.5    Brown, M.C.6    Morrow, B.E.7
  • 14
    • 0035263599 scopus 로고    scopus 로고
    • Lindsay, E. A.; Vitelli, F.; Su, H.; Morishima, M.; Huynh, T.; Pramparo, T.; Jurecic, V.; Ogunrinu, G.; Sutherland, H. F.; Scam- bler, P. J.; Bradley, A.; Baldini, A. Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice. Nature 2001, 410, 97-101.
    • Lindsay, E. A.; Vitelli, F.; Su, H.; Morishima, M.; Huynh, T.; Pramparo, T.; Jurecic, V.; Ogunrinu, G.; Sutherland, H. F.; Scam- bler, P. J.; Bradley, A.; Baldini, A. Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice. Nature 2001, 410, 97-101.
  • 16
    • 33745239739 scopus 로고    scopus 로고
    • Fgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutants
    • Vitelli, F.; Zhang, Z.; Huynh, T.; Sobotka, A.; Mupo, A.; Baldini, A. Fgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutants. Dev. Biol. 2006, 295, 559-70.
    • (2006) Dev. Biol , vol.295 , pp. 559-570
    • Vitelli, F.1    Zhang, Z.2    Huynh, T.3    Sobotka, A.4    Mupo, A.5    Baldini, A.6
  • 17
    • 9444265974 scopus 로고    scopus 로고
    • Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors
    • Hu, T.; Yamagishi, H.; Maeda, J.; McAnally, J.; Yamagishi, C.; Srivastava, D. Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors. Development 2004, 131, 5491-502.
    • (2004) Development , vol.131 , pp. 5491-5502
    • Hu, T.1    Yamagishi, H.2    Maeda, J.3    McAnally, J.4    Yamagishi, C.5    Srivastava, D.6
  • 18
    • 33947362415 scopus 로고    scopus 로고
    • Visualization of outflow tract development in the absence of Tbx1 using an Fgf10 enhancer trap transgene
    • Kelly, R. G.; Papaioannou, V. E. Visualization of outflow tract development in the absence of Tbx1 using an Fgf10 enhancer trap transgene. Dev. Dyn. 2007, 236, 821-8.
    • (2007) Dev. Dyn , vol.236 , pp. 821-828
    • Kelly, R.G.1    Papaioannou, V.E.2
  • 19
    • 4043094751 scopus 로고    scopus 로고
    • Baldini ATbx1 has a dual role in the morphogenesis of the cardiac outflow tract
    • Xu, H.; Morishima, M.; Wylie, J. N.; Schwartz, R. J.; Bruneau, B. G.; Lindsay, E. A. Baldini ATbx1 has a dual role in the morphogenesis of the cardiac outflow tract. Development 2004, 131, 3217-27.
    • (2004) Development , vol.131 , pp. 3217-3227
    • Xu, H.1    Morishima, M.2    Wylie, J.N.3    Schwartz, R.J.4    Bruneau, B.G.5    Lindsay, E.A.6
  • 20
    • 29744455342 scopus 로고    scopus 로고
    • Dose- dependent interaction of Tbx1 and Crkl and locally aberrant RA signalling in a model of del22q11 syndrome
    • Guris, D.; Duester, G.; Papaioannou, V. E.; Imamoto, A. Dose- dependent interaction of Tbx1 and Crkl and locally aberrant RA signalling in a model of del22q11 syndrome. Dev. Cell 2006, 10, 81-92.
    • (2006) Dev. Cell , vol.10 , pp. 81-92
    • Guris, D.1    Duester, G.2    Papaioannou, V.E.3    Imamoto, A.4
  • 21
    • 33751375645 scopus 로고    scopus 로고
    • Cyp26 genes a1, b1 and c1 are down-regulated in Tbx1 null mice and inhibition of Cyp26 enzyme function produces a phenocopy of DiGeorge Syndrome in the chick
    • Roberts, C.; Ivins, S.; Cook, A. C.; Baldini, A.; Scambler, P. J. Cyp26 genes a1, b1 and c1 are down-regulated in Tbx1 null mice and inhibition of Cyp26 enzyme function produces a phenocopy of DiGeorge Syndrome in the chick. Hum. Mol. Genet. 2006, 15, 3394-10.
    • (2006) Hum. Mol. Genet , vol.15 , pp. 3394-3410
    • Roberts, C.1    Ivins, S.2    Cook, A.C.3    Baldini, A.4    Scambler, P.J.5
  • 22
    • 19444371444 scopus 로고    scopus 로고
    • Dissecting contiguous gene defects: TBX1. Proteomics in 2002: a year of technical development and wide-ranging applications
    • Baldini, A. Dissecting contiguous gene defects: TBX1. Proteomics in 2002: a year of technical development and wide-ranging applications. Curr. Opin. Genet. Dev. 2005, 15, 279-84.
    • (2005) Curr. Opin. Genet. Dev , vol.15 , pp. 279-284
    • Baldini, A.1
  • 23
    • 0038116819 scopus 로고    scopus 로고
    • Proteomics in 2002: A year of technical development and wide-ranging applications
    • Figeys, D. Proteomics in 2002: a year of technical development and wide-ranging applications. Anal. Chem. 2003, 75, 2981-2905.
    • (2003) Anal. Chem , vol.75 , pp. 2981-2905
    • Figeys, D.1
  • 25
    • 0036463947 scopus 로고    scopus 로고
    • Evaluation of two-dimensional differential gel electrophoresis for proteomic expression analysis of a model breast cancer cell system
    • Gharbi, S.; Gaffney, P.; Yang, A.; Zvelebil, M. J.; Cramer, R.; Waterfield, M. D.; Timms, J. F. Evaluation of two-dimensional differential gel electrophoresis for proteomic expression analysis of a model breast cancer cell system. Mol. Cell. Proteomics 2002, 1, 91-98.
    • (2002) Mol. Cell. Proteomics , vol.1 , pp. 91-98
    • Gharbi, S.1    Gaffney, P.2    Yang, A.3    Zvelebil, M.J.4    Cramer, R.5    Waterfield, M.D.6    Timms, J.F.7
  • 26
    • 21244495253 scopus 로고    scopus 로고
    • The development of the DIGE system: 2D fluorescence difference gel analysis technology
    • Marouga, R.; David, S.; Hawkins, E. The development of the DIGE system: 2D fluorescence difference gel analysis technology. Anal. Bioanal. Chem. 2005, 382, 669-678.
    • (2005) Anal. Bioanal. Chem , vol.382 , pp. 669-678
    • Marouga, R.1    David, S.2    Hawkins, E.3
  • 28
    • 0033434080 scopus 로고    scopus 로고
    • Probability- based protein identification by searching sequence databases using mass spectrometry data
    • Perkins, D. N.; Pappin, D. J.; Creasy, D. M.; Cottrell, J. S. Probability- based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 1999, 20, 3551-67.
    • (1999) Electrophoresis , vol.20 , pp. 3551-3567
    • Perkins, D.N.1    Pappin, D.J.2    Creasy, D.M.3    Cottrell, J.S.4
  • 29
    • 33646706385 scopus 로고    scopus 로고
    • Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in secondary heart field. identification of downstream genetic pathways of Tbx1 in the second heart field
    • Nowotschin, S.; Liao, J.; Gage, P. J.; Epstein, J. A.; Campione, M.; Morrow, B. E. Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in secondary heart field. identification of downstream genetic pathways of Tbx1 in the second heart field. Development 2006, 133, 1565-73.
    • (2006) Development , vol.133 , pp. 1565-1573
    • Nowotschin, S.1    Liao, J.2    Gage, P.J.3    Epstein, J.A.4    Campione, M.5    Morrow, B.E.6
  • 30
    • 5444261739 scopus 로고    scopus 로고
    • Retinoic acid signalling in the development of branchial arches
    • Mark, M.; Ghyselinck, N. B.; Chambon, P. Retinoic acid signalling in the development of branchial arches. Curr. Opin. Genet. Dev. 2004, 14, 591-598.
    • (2004) Curr. Opin. Genet. Dev , vol.14 , pp. 591-598
    • Mark, M.1    Ghyselinck, N.B.2    Chambon, P.3
  • 31
    • 0038686798 scopus 로고    scopus 로고
    • The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system
    • Niederreither, K.; Vermot, J.; Le Roux, I.; Schuhbaur, B.; Chambon, P.; Dolle, P. The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system. Development 2003, 130 (11), 2525-34.
    • (2003) Development , vol.130 , Issue.11 , pp. 2525-2534
    • Niederreither, K.1    Vermot, J.2    Le Roux, I.3    Schuhbaur, B.4    Chambon, P.5    Dolle, P.6
  • 32
    • 0037452691 scopus 로고    scopus 로고
    • Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice
    • Vermot, J.; Niederreither, K.; Garnier, J. M.; Chambon, P.; Dolle, P. Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 1763-8.
    • (2003) Proc. Natl. Acad. Sci. U.S.A , vol.100 , pp. 1763-1768
    • Vermot, J.1    Niederreither, K.2    Garnier, J.M.3    Chambon, P.4    Dolle, P.5
  • 33
    • 0032958632 scopus 로고    scopus 로고
    • Embryonic retinoic acid synthesis is essential for early mouse post- implantation development
    • Niederreither, K.; Subbarayan, V.; Dolle, P.; Chambon, P. Embryonic retinoic acid synthesis is essential for early mouse post- implantation development. Nat. Genet. 1999, 21, 346-7.
    • (1999) Nat. Genet , vol.21 , pp. 346-347
    • Niederreither, K.1    Subbarayan, V.2    Dolle, P.3    Chambon, P.4
  • 34
  • 35
  • 37
    • 0028203494 scopus 로고
    • Expression of the atrial-specific myosin heavy chain AMHC1 and the establishment of anteroposterior polarity in the developing chicken heart
    • Yutzey, K. E.; Rhee, J. T.; Bader, D. Expression of the atrial-specific myosin heavy chain AMHC1 and the establishment of anteroposterior polarity in the developing chicken heart. Development 1994, 120, 871-883.
    • (1994) Development , vol.120 , pp. 871-883
    • Yutzey, K.E.1    Rhee, J.T.2    Bader, D.3
  • 38
    • 41149107746 scopus 로고    scopus 로고
    • Liao, J.; Aggarwal, V. S.; Nowotschin, S.; Bondraev, A.; Lipner, S.; Morrow, B. E. identification of downstream genetic pathways of Tbx1 in the second heart field. Dev. Biol. 2008, 316, 524-537.
    • Liao, J.; Aggarwal, V. S.; Nowotschin, S.; Bondraev, A.; Lipner, S.; Morrow, B. E. identification of downstream genetic pathways of Tbx1 in the second heart field. Dev. Biol. 2008, 316, 524-537.
  • 39
    • 18744373632 scopus 로고    scopus 로고
    • PCNA in situ hybridization: A novel and reliable tool for detection of dynamic changes in proliferative activity
    • Kohler, T.; Prols, F.; Brand-Saberi, B. PCNA in situ hybridization: a novel and reliable tool for detection of dynamic changes in proliferative activity. Histochem. Cell Biol. 2005, 123, 315-27.
    • (2005) Histochem. Cell Biol , vol.123 , pp. 315-327
    • Kohler, T.1    Prols, F.2    Brand-Saberi, B.3
  • 42
    • 33750920449 scopus 로고    scopus 로고
    • Protein degradation by the 26S proteasome system in the normal and stressed myocardium
    • Gomes, A. V.; Zong, C.; Ping, P. Protein degradation by the 26S proteasome system in the normal and stressed myocardium. Antioxid. Redox Signaling 2006, 8, 1677-91.
    • (2006) Antioxid. Redox Signaling , vol.8 , pp. 1677-1691
    • Gomes, A.V.1    Zong, C.2    Ping, P.3
  • 43
    • 34547731900 scopus 로고    scopus 로고
    • Dynamic and selective interactions of the transcriptional corepressor TIF1β with the heterochromatin protein HP1 isotypes during cell differentiation
    • Cammas, F.; Janoshazi, A.; Lerouge, T.; Losson, R. Dynamic and selective interactions of the transcriptional corepressor TIF1β with the heterochromatin protein HP1 isotypes during cell differentiation. Differentiation 2007, 75, 627-34.
    • (2007) Differentiation , vol.75 , pp. 627-634
    • Cammas, F.1    Janoshazi, A.2    Lerouge, T.3    Losson, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.