Stem cells and models of astrocytomas

Clinical and Investigative Medicine

Volumn 32, Issue 2, 2009, Pages

  Kamnasaran, Deepak ^a,b  

^a UNIVERSITÉ LAVAL   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

TEMOZOLOMIDE;

ASTROCYTOMA; CANCER CHEMOTHERAPY; CANCER CLASSIFICATION; CANCER STEM CELL; CELL DIFFERENTIATION; CLINICAL ASSESSMENT; CLINICAL FEATURE; DISEASE COURSE; EMBRYONIC STEM CELL; EXTERNAL BEAM RADIOTHERAPY; GLIOBLASTOMA; HISTOPATHOLOGY; HUMAN; MULTIDRUG RESISTANCE; MUTATIONAL ANALYSIS; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; TUMOR GROWTH; WORLD HEALTH ORGANIZATION;

ANIMALS; ASTROCYTOMA; HUMANS; MODELS, BIOLOGICAL; STEM CELLS;

EID: 65249119722     PISSN: 0147958X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (99)

1. American Cancer Society. Cancer facts and figures- 2001. Atlanta (GA): American Cancer Society (2001).
2. Surawicz, TS, et al. Descriptive epidemiology of primary brain and CNS tumors: results from the Central Brain Tumor Registry of the United States, 1990-1994. Neurooncology 1999 1:14-25.
3. Kleihues P, Cavenee WK. Pathology and Genetics of tumors of the nervous system: World Health Organization Classification of tumors. Oxford, Oxford Press 2000.
4. Stupp R, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005 352:987-96.
5. Rasheed BK, et al. Molecular pathogenesis of malignant gliomas. Curr Opin Oncol. 1999 11, 162-7.
6. Louis DN, Gusella JF. A tiger behind many doors: multiple genetic pathways to malignant glioma. Trends Genet. 1995;11:412-5.
7. Besson A, Yong VW. Mitogenic signaling and the relationship to cell cycle regulation in astrocytomas. J Neurooncol. 2001;51:245-64.
8. Huang, H., et al. Gene expression profiling of low- grade diffuse astrocytomas by cDNA arrays. Cancer Res.2000;60:6868-74.
9. Freije, W.A., et al. Gene expression profiling of glio- mas strongly predicts survival. Cancer Res. 2004;64:6503-10.
10. Otomo, T, et al. Microarray analysis of temporal gene responses to ionizing radiation in two glioblastoma cell lines: up-regulation of DNA repair genes. J Radiat Res (Tokyo). 2004 45, 53-60.
11. Mischel, PS, et al. Identification of molecular subtypes of glioblastoma by gene expression profiling. Onco- gene. 2003;22:2361-73.
12. Qi ZY, et al. Isolation of novel differentially expressed genes related to human glioma using cDNA microarray and characterizations of two novel full-length genes. J Neurooncol. 2002;56:197-208.
13. Kotliarov Y, et al. High-resolution Global Genomic Survey of 178 Gliomas Reveals Novel Regions of Copy Number Alteration and Allelic Imbalances. Cancer Res 2006;66:9428-36.
14. Maher EA, et al. Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities. Cancer Res. 2006;66:11502-13.
15. Dai C, et al. PDGF autocrine stimulation dedifferenti- ates cultured astrocytes and induces oligodendroglio- mas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev. 2001;15:1913-25.
16. Sanai N, Alvarez-Buylla A, Berger MS. Neural stem cells and the origin of gliomas. N Engl J Med. 2005;353:811-22.
17. Doetsch F, et al. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell. 1999;97:703-16.
18. Hopewell JW. The subependymal plate and the genesis of gliomas. J Pathol. 1975 ;117:101-3.
19. Lantos PL, Cox DJ. The origin of experimental brain tumors: a sequential study. Experimentia 1976;32:1467-8.
20. Vick NA, Lin MJ, Bigner DD. The role of the sube-pendymal plate in glial tumorigenesis. Acta Neuropathol (Berl). 1977;40:63-71.
21. Holland EC, et al. A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. Genes Dev. 1998 12:3675-85.
22. Holland EC, et al. Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat Genet. 2000 25:55-7.
23. Uhrbom L, et al. Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt. Cancer Res. 2002;62:5551-8.
24. Marumoto T, et al. Development of a novel mouse glioma model using lentiviral vectors. Nat Med. 2009;15:110-6.
25. Bewley MC, et al. Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR. Science. 1999;286(5444):1579-83.
26. Zhu Y, et al. Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant as- trocytoma. Cancer Cell. 2005;8:119-30.
27. Sonoda Y, et al. Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma. Cancer Res. 2001a:61:4956-60.
28. Sonoda Y, et al. Akt pathway activation converts anaplastic astrocytoma to glioblastoma multiforme in a human astrocyte model of glioma. Cancer Res. 2001b;61:6674-8.
29. Kamnasaran D, et al. GATA6 is an astrocytoma tumor suppressor gene identified by gene trapping of mouse glioma model. Proc Natl Acad Sci U S A. 2007;104:8053-8.
30. Biernaskie JA, et al. Isolation of skin-derived precursors (SKPs) and differentiation and enrichment of their Schwann cell progeny. Nat Protoc. 2006;1:2803-12.
31. Biernaskie J, et al. Skin-derived precursors generate myelinating Schwann cells that promote remyelination and functional recovery after contusion spinal cord injury. J Neurosci. 2007;27:9545-59.
32. Bachoo RM, et al. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell. 2002;1:269-77.
33. Kamnasaran D, Hawkins C, Guha A. Characterization and transformation potential of "Synthetic" astrocytes differentiated from murine embryonic stem cells. Glia. 2008;56:457-70.
34. Jang YK, et al. Retinoic acid-mediated induction of neurons and glial cells from human umbilical cord- derived hematopoietic stem cells. J Neurosci Res. 2004;75:573-84.
35. Lee MW, et al. Neural differentiation of novel multipo- tent progenitor cells from cryopreserved human umbilical cord blood. Biochem Biophys Res Commun. 2007;358:637-43.
36. Mokrý J, Karbanova J, Filip S. Differentiation potential of murine neural stem cells in vitro and after transplantation. Transplant Proc. 2005 ;37:268-72.
37. Rao MS, Noble M, Mayer-Pröschel M. A tripotential glial precursor cell is present in the developing spinal cord. Proc Natl Acad Sci U S A. 1998;95:3996-4001.
38. Yang SY, Liu H, Zhang JN. Gene therapy of rat malignant gliomas using neural stem cells expressing IL-12. DNA Cell Biol. 2004;23:381-9.
39. Tang F, et al. Differentiation of embryonic stem cell to astrocytes visualized by green fluorescent protein. Cell Mol Neurobiol. 2002;22:95-101.
40. Mi H, Haeberle H, Barres BA. Induction of astrocyte differentiation by endothelial cells. J Neurosci. 2001;21:1538-47.
41. Chang MY, et al. Neurons and astrocytes secrete factors that cause stem cells to differentiate into neurons and astrocytes, respectively. Mol Cell Neurosci. 2003;23:414-26.
42. Jori FP, et al. EGF-responsive rat neural stem cells: molecular follow-up of neuron and astrocyte differentiation in vitro. J Cell Physiol. 2003;195:220-33.
43. Rajan P, McKay RD. Multiple routes to astrocytic differentiation in the CNS. J Neurosci. 1998;18:3620-9.
44. Satoh M, Sugino H, Yoshida T. Activin promotes astro- cytic differentiation of a multipotent neural stem cell line and an astrocyte progenitor cell line from murine central nervous system. Neurosci Lett. 2000;284:143-6.
45. Hajihosseini MK, Dickson C. A subset of fibroblast growth factors (Fgfs) promote survival, but Fgf-8b specifically promotes astroglial differentiation of rat cortical precursor cells. Mol Cell Neurosci. 1999;14:468-85.
46. Mabie PC, et al. Bone morphogenetic proteins induce astroglial differentiation of oligodendroglial-astroglial progenitor cells. J Neurosci. 1997;17:4112-20.
47. Reynolds BA, Weiss S. Generation of neurons and as- trocytes from isolated cells of the adult mammalian central nervous system. Science. 1992;255:1707-10.
48. Kilpatrick TJ, Bartlett PF. Cloning and growth of mul- tipotential neural precursors: requirements for proliferation and differentiation. Neuron. 1993;10:255-65.
49. Temple S. The development of neural stem cells. Nature. 2001 ;414:112-7.
50. Colombo E, et al. Embryonic stem-derived versus somatic neural stem cells: a comparative analysis of their developmental potential and molecular phenotype. Stem Cells. 2006;24:825-34.
51. Lim JK, et al. Brain-derived neurotrophic factor stimulates the neural differentiation of human umbilical cord blood-derived mesenchymal stem cells and survival of differentiated cells through MAPK/ERK and PI3K/Akt-dependent signaling pathways. J Neurosci Res. 2008;86:2168-78.
52. Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature. 1981;292:154-6.
53. Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A. 1981;78:7634-8.
54. Thomson JA, et al. Isolation of a primate embryonic stem cell line. Proc Natl Acad Sci U S A. 1995;92:7844-8.
55. Thomson JA, et al. Pluripotent cell lines derived from common marmoset (Callithrix jacchus) blastocysts. Biol Reprod. 1996;55:254-9.
56. Thomson JA, et al. Embryonic stem cell lines derived from human blastocysts. Science. 1998;282:1145-7.
57. Suemori H, et al. Establishment of embryonic stem cell lines from cynomolgus monkey blastocysts produced by IVF or ICSI. Dev Dyn. 2001;222:273-9.
58. Reubinoff BE, et al. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat Biotechnol. 2000;18:399-404.
59. Brustle O, et al., Embryonic stem cell-derived glial precursors: a source of myelinating transplants. Science. 1999;285:754-6.
60. Fraichard A, et al. In vitro differentiation of embryonic stem cells into glial cells and functional neurons. J Cell Sci. 1995;108:3181-8.
61. Slager HG, et al. Transforming growth factor-beta in the early mouse embryo: implications for the regulation of muscle formation and implantation. Dev Genet. 1993;14:212-24.
62. Palmer TD, et al. Cell culture. Progenitor cells from human brain after death. Nature 2001;411:42-3.
63. Gomes WA, Mehler MF, Kessler JA. Transgenic over- expression of BMP4 increases astroglial and decreases oligodendroglial lineage commitment. Dev Biol. 2003;255:164-77.
64. Nakashima K, et al. Astrocyte differentiation mediated by LIF in cooperation with BMP2. FEBS Lett. 1999;457:43-6.
65. Fan Y, Melhem MF, Chaillet JR. Forced expression of the homeobox-containing gene Pem blocks differentiation of embryonic stem cells. Dev Biol. 1999;210:481-96.
66. Groszer M, et al. Negative regulation of neural stem/ progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science. 2001;294:2186-9.
67. Kielman MF, et al. Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling. Nat Genet. 2002;32:594-605.
68. Penninger JM, Woodgett J. Stem cells. PTEN-- coupling tumor suppression to stem cells? Science. 2001 ;294:2116-8.
69. Field SJ, et al. Growth and differentiation of embryonic stem cells that lack an intact c-fos gene. Proc Natl Acad Sci U S A. 1992;89:9306-10.
70. Clarke MF, et al. Cancer stem cells-perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res. 2006;66:9339-44.
71. Ignatova TN, et al. Human cortical glial tumors contain neural stem-like cells expressing astroglial and neu- ronal markers in vitro. Glia. 2002 ;39:193-206.
72. Hemmati HD, et al. Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci U S A. 2003;100:15178-83.
73. Galli R, et al. Isolation and characterization of tumori- genic, stem-like neural precursors from human glio- blastoma. Cancer Res. 2004;64:7011-21.
74. Singh SK, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res. 2003;63:5821-8.
75. Singh SK, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res. 2003;63:5821-8.
76. Yuan X, et al. Isolation of cancer stem cells from adult glioblastoma multiforme. Oncogene. 2004;23:9392-400.
77. Rebetz J, et al. Glial progenitor-like phenotype in low- grade glioma and enhanced CD133-expression and neuronal lineage differentiation potential in high-grade glioma. PLoS ONE. 2008;3:e1936.
78. Kondo T, Setoguchi T, Taga T. Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci U S A. 2004;101:781-6.
79. Yu SC, et al. Isolation and characterization of cancer stem cells from a human glioblastoma cell line U87. Cancer Lett. 2008;265:124-34.
80. Bao S, et al., Glioma stem cells promote radioresis- tance by preferential activation of the DNA damage response. Nature. 2006;444:756-60.
81. Liu G, et al. Analysis of gene expression and chemore- sistance of CD133+ cancer stem cells in glioblastoma. Mol Cancer. 2006;5:67.
82. Salmaggie A, et al. Glioblastoma-derived tumoro- spheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype. Glia. 2006;54:850-60.
83. Kang MK, Kang SK. Tumorigenesis of chemothera- peutic drug-resistant cancer stem-like cells in brain glioma. Stem Cells Dev. 2007;16:837-47.
84. Sanai N, et al. Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration. Nature. 200; 427:740-4.
85. Doetsch F. The glial identity of neural stem cells. Nat Neurosci. 2003;6:1127-34.
86. Jackson EL, et al. PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma- like growths in response to increased PDGF signaling. Neuron. 2006;51:187-99.
87. Beier D, et al. CD133(+) and CD133(-) glioblastoma- derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res. 2007;67:4010-5.
88. Carpenter MK, et al. Properties of four human embryonic stem cell lines maintained in a feeder-free culture system. Dev Dyn. 2004;229:243-58.
89. Serakinci N, Graakjaer J, Kolvraa S. Telomere stability and telomerase in mesenchymal stem cells. Biochimie. 2008;90:33-40.
90. Varghese M, et al. A comparison between stem cells from the adult human brain and from brain tumors. Neurosurgery. 2008;63:1022-33.
91. Tunici P, et al. Genetic alterations and in vivo tumori- genicity of neurospheres derived from an adult glio- blastoma. Mol Cancer. 2004 ;3:25.
92. Calabrese C, et al. A perivascular niche for brain tumor stem cells. Cancer Cell. 2007;11:69-82.
93. Lefranc F, et al. Present and potential future issues in glioblastoma treatment. Expert Rev Anticancer Ther. 2006;6:719-32.
94. Lee J, Kotliarova S, Kotliarov Y, et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell. 2006;9:391-403.
95. Walker MD, et al. Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery. N Engl J Med. 1980;303:1323-9.
96. Taphoorn MJ et al. Health-related quality of life in patients with glioblastoma: a randomised controlled trial. Lancet Oncol. 2005;6:937-44.
97. Lu C, Shervington A. Chemoresistance in gliomas. Mol Cell Biochem. 2008 ;312:71-80.
98. Denny BJ, et al. NMR and molecular modeling investigation of the mechanism of activation of the antitu- mor drug temozolomide and its interaction with DNA. Biochemistry. 1994;33:9045-51.
99. Diamandis P, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73