Enhanced functional recombinant factor VII production by HEK 293 cells stably transfected with VKORC1 where the gamma-carboxylase inhibitor calumenin is stably suppressed by shRNA transfection

Thrombosis Research

Volumn 122, Issue 3, 2008, Pages 405-410

  Wajih, Nadeem ^a   Owen, John ^a   Wallin, Reidar ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Gamma carboxylation; Recombinant factor VII; Vitamin K; Vitamin K dependent coagulation factors

Indexed keywords

BLOOD CLOTTING FACTOR 7; CALCIUM BINDING PROTEIN; CALUMENIN; CARBOXYLASE; PROTEIN VKORC1; RECOMBINANT PROTEIN; SHORT HAIRPIN RNA; VITAMIN K GROUP;

ARTICLE; BIOTECHNOLOGY; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CALCIUM-BINDING PROTEINS; CELL LINE; CLONING, MOLECULAR; FACTOR VII; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; KIDNEY; MIXED FUNCTION OXYGENASES; PLASMIDS; PROTEIN ENGINEERING; RATS; RECOMBINANT PROTEINS; RNA INTERFERENCE; TRANSFECTION;

EID: 45849118365     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2007.11.002     Document Type: Article

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