-
1
-
-
0031824782
-
Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity
-
Geula C, Wu CK, Saroff D, Lorenzo A, Yuan M, Yankner BA. Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity. Nat Med 1998; 4: 827-31.
-
(1998)
Nat Med
, vol.4
, pp. 827-831
-
-
Geula, C.1
Wu, C.K.2
Saroff, D.3
Lorenzo, A.4
Yuan, M.5
Yankner, B.A.6
-
2
-
-
0033570337
-
Protofbrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
-
Hartley DM, Walsh DM, Ye CP, Diehl T, Vasquez S, Vassilev PM, et al. Protofbrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J Neurosci 1999; 19: 8876-84.
-
(1999)
J Neurosci
, vol.19
, pp. 8876-8884
-
-
Hartley, D.M.1
Walsh, D.M.2
Ye, C.P.3
Diehl, T.4
Vasquez, S.5
Vassilev, P.M.6
-
3
-
-
0030569357
-
Betaamyloid induces apoptosis in human-derived neurotypic SH-SY5Y cells
-
Li YP, Bushnell AF, Lee CM, Perlmutter LS, Wong SK. Betaamyloid induces apoptosis in human-derived neurotypic SH-SY5Y cells. Brain Res 1996; 738: 196-204.
-
(1996)
Brain Res
, vol.738
, pp. 196-204
-
-
Li, Y.P.1
Bushnell, A.F.2
Lee, C.M.3
Perlmutter, L.S.4
Wong, S.K.5
-
4
-
-
0030808462
-
Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" patern of gene induction
-
Estus S, Tucker HM, van Rooyen C, Wright S, Brigham EF, Wogulis M, et al. Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" patern of gene induction. J Neurosci 1997; 17: 7736-45.
-
(1997)
J Neurosci
, vol.17
, pp. 7736-7745
-
-
Estus, S.1
Tucker, H.M.2
van Rooyen, C.3
Wright, S.4
Brigham, E.F.5
Wogulis, M.6
-
5
-
-
0026513962
-
Evidence for a membrane defect in Alzheimer disease brain
-
Nitsch RM, Blusztajn JK, Pittas AG, Slack BE, Growdon JH, Wurtman RJ. Evidence for a membrane defect in Alzheimer disease brain. Proc Natl Acad Sci USA 1992; 89: 1671-5.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 1671-1675
-
-
Nitsch, R.M.1
Blusztajn, J.K.2
Pittas, A.G.3
Slack, B.E.4
Growdon, J.H.5
Wurtman, R.J.6
-
6
-
-
0025685621
-
Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer's disease but not of Down's syndrome patients
-
Blusztajn JK, Lopez Gonzalez-Coviella I, Logue M, Growdon JH, Wurtman RJ. Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer's disease but not of Down's syndrome patients. Brain Res 1990; 536: 240-4.
-
(1990)
Brain Res
, vol.536
, pp. 240-244
-
-
Blusztajn, J.K.1
Lopez Gonzalez-Coviella, I.2
Logue, M.3
Growdon, J.H.4
Wurtman, R.J.5
-
7
-
-
0033791814
-
Membrane breakdown in acute and chronic neurodegeneration: Focus on choline-containing phospholipids
-
Klein J. Membrane breakdown in acute and chronic neurodegeneration: focus on choline-containing phospholipids. J Neural Transm 2000; 107: 1027-63.
-
(2000)
J Neural Transm
, vol.107
, pp. 1027-1063
-
-
Klein, J.1
-
8
-
-
0036753272
-
Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death
-
Buterfeld DA, Castegna A, Lauderback CM, Drake J. Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death. Neurobiol Aging 2002; 23: 655-64.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 655-664
-
-
Buterfeld, D.A.1
Castegna, A.2
Lauderback, C.M.3
Drake, J.4
-
9
-
-
37549004312
-
Role of lysophosphatidyl-choline (LPC) in atherosclerosis
-
Matsumoto T, Kobayashi T, Kamata K. Role of lysophosphatidyl-choline (LPC) in atherosclerosis. Curr Med Chem 2007; 14: 3209-20.
-
(2007)
Curr Med Chem
, vol.14
, pp. 3209-3220
-
-
Matsumoto, T.1
Kobayashi, T.2
Kamata, K.3
-
10
-
-
0015303575
-
Te efect of injections of lysophosphatidyl choline into white mater of the adult mouse spinal cord
-
Hall SM. Te efect of injections of lysophosphatidyl choline into white mater of the adult mouse spinal cord. J Cell Sci 1972; 10: 535-46.
-
(1972)
J Cell Sci
, vol.10
, pp. 535-546
-
-
Hall, S.M.1
-
11
-
-
0037117751
-
Axonal lesions and PDGF-enhanced remyelination in the rat corpus callosum afer lysolecithin demyelination
-
Jean I, Allamargot C, Barthelaix-Pouplard A, Fressinaud C. Axonal lesions and PDGF-enhanced remyelination in the rat corpus callosum afer lysolecithin demyelination. Neuroreport 2002; 13: 627-31.
-
(2002)
Neuroreport
, vol.13
, pp. 627-631
-
-
Jean, I.1
Allamargot, C.2
Barthelaix-Pouplard, A.3
Fressinaud, C.4
-
12
-
-
1342269759
-
Novel mechanisms and approaches in the study of neurodegeneration and neuroprotection. a review
-
Kostrzewa RM, Segura-Aguilar J. Novel mechanisms and approaches in the study of neurodegeneration and neuroprotection. a review. Neurotox Res 2003; 5: 375-83.
-
(2003)
Neurotox Res
, vol.5
, pp. 375-383
-
-
Kostrzewa, R.M.1
Segura-Aguilar, J.2
-
13
-
-
9144238052
-
Alzheimer neurofbrillary degeneration: Therapeutic targets and high-throughput assays
-
Iqbal K, Alonso Adel C, El-Akkad E, Gong CX, Haque N, Khatoon S, et al. Alzheimer neurofbrillary degeneration: therapeutic targets and high-throughput assays. J Mol Neurosci 2003; 20: 425-9.
-
(2003)
J Mol Neurosci
, vol.20
, pp. 425-429
-
-
Iqbal, K.1
Alonso Adel, C.2
El-Akkad, E.3
Gong, C.X.4
Haque, N.5
Khatoon, S.6
-
14
-
-
0037853135
-
The lysophospholipid receptor G2A activates a specifc combination of G proteins and promotes apoptosis
-
Lin P, Ye RD. The lysophospholipid receptor G2A activates a specifc combination of G proteins and promotes apoptosis. J Biol Chem 2003; 278: 14379-86.
-
(2003)
J Biol Chem
, vol.278
, pp. 14379-14386
-
-
Lin, P.1
Ye, R.D.2
-
15
-
-
0035958728
-
Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A
-
Kabarowski JH, Zhu K, Le LQ, Wite ON, Xu Y. Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A. Science 2001; 293: 702-5.
-
(2001)
Science
, vol.293
, pp. 702-705
-
-
Kabarowski, J.H.1
Zhu, K.2
Le, L.Q.3
Wite, O.N.4
Xu, Y.5
-
16
-
-
3943092621
-
Pathways towards and away from Alzheimer's disease
-
Mattson MP. Pathways towards and away from Alzheimer's disease. Nature 2004; 430: 631-9.
-
(2004)
Nature
, vol.430
, pp. 631-639
-
-
Mattson, M.P.1
-
17
-
-
0037135111
-
Te amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J, Selkoe DJ. Te amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002; 297: 353-6.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
18
-
-
0034643895
-
Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells
-
Misonou H, Morishima-Kawashima M, Ihara Y. Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells. Biochemistry 2000; 39: 6951-9.
-
(2000)
Biochemistry
, vol.39
, pp. 6951-6959
-
-
Misonou, H.1
Morishima-Kawashima, M.2
Ihara, Y.3
-
19
-
-
0034673209
-
Oxidative stress induces increase in intracellular amyloid beta-protein production and selective activation of betaI and betaII PKCs in NT2 cells
-
Paola D, Domenicotti C, Nitti M, Vitali A, Borghi R, Cottalasso D, et al. Oxidative stress induces increase in intracellular amyloid beta-protein production and selective activation of betaI and betaII PKCs in NT2 cells. Biochem Biophys Res Commun 2000; 268: 642-6.
-
(2000)
Biochem Biophys Res Commun
, vol.268
, pp. 642-646
-
-
Paola, D.1
Domenicotti, C.2
Nitti, M.3
Vitali, A.4
Borghi, R.5
Cottalasso, D.6
-
20
-
-
2642544767
-
Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice
-
Li F, Calingasan NY, Yu F, Mauck WM, Toidze M, Almeida CG, et al. Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice. J Neurochem 2004; 89: 1308-12.
-
(2004)
J Neurochem
, vol.89
, pp. 1308-1312
-
-
Li, F.1
Calingasan, N.Y.2
Yu, F.3
Mauck, W.M.4
Toidze, M.5
Almeida, C.G.6
-
21
-
-
0031038918
-
Alzheimer's disease: Genotypes, phenotypes, and treatments
-
Selkoe DJ. Alzheimer's disease: genotypes, phenotypes, and treatments. Science 1997; 275: 630-1.
-
(1997)
Science
, vol.275
, pp. 630-631
-
-
Selkoe, D.J.1
-
22
-
-
0038117796
-
Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline
-
Naslund J, Haroutunian V, Mohs R, Davis KL, Davies P, Greengard P, et al. Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. JAMA 2000; 283: 1571-7.
-
(2000)
JAMA
, vol.283
, pp. 1571-1577
-
-
Naslund, J.1
Haroutunian, V.2
Mohs, R.3
Davis, K.L.4
Davies, P.5
Greengard, P.6
-
23
-
-
0034652232
-
Caspase-2 mediates neuronal cell death induced by beta-amyloid
-
Troy CM, Rabacchi SA, Friedman WJ, Frappier TF, Brown K, Shelanski ML. Caspase-2 mediates neuronal cell death induced by beta-amyloid. J Neurosci 2000; 20: 1386-92.
-
(2000)
J Neurosci
, vol.20
, pp. 1386-1392
-
-
Troy, C.M.1
Rabacchi, S.A.2
Friedman, W.J.3
Frappier, T.F.4
Brown, K.5
Shelanski, M.L.6
-
24
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, et al. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 2000; 403: 98-103.
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
-
25
-
-
0033551738
-
Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease
-
LeBlanc A, Liu H, Goodyer C, Bergeron C, Hammond J. Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease. J Biol Chem 1999; 274: 23426-36.
-
(1999)
J Biol Chem
, vol.274
, pp. 23426-23436
-
-
LeBlanc, A.1
Liu, H.2
Goodyer, C.3
Bergeron, C.4
Hammond, J.5
-
26
-
-
0033593456
-
Multiple pathways of apoptosis in PC12 cells. CrmA inhibits apoptosis induced by beta-amyloid
-
Ivins KJ, Ivins JK, Sharp JP, Cotman CW. Multiple pathways of apoptosis in PC12 cells. CrmA inhibits apoptosis induced by beta-amyloid. J Biol Chem 1999; 274: 2107-12.
-
(1999)
J Biol Chem
, vol.274
, pp. 2107-2112
-
-
Ivins, K.J.1
Ivins, J.K.2
Sharp, J.P.3
Cotman, C.W.4
-
27
-
-
0028981717
-
The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice
-
LaFerla FM, Tinkle BT, Bieberich CJ, Haudenschild CC, Jay G. The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice. Nat Genet 1995; 9: 21-30.
-
(1995)
Nat Genet
, vol.9
, pp. 21-30
-
-
LaFerla, F.M.1
Tinkle, B.T.2
Bieberich, C.J.3
Haudenschild, C.C.4
Jay, G.5
-
28
-
-
0028171547
-
Ultrastructural analysis of beta-amyloid-induced apoptosis in cultured hippocampal neurons
-
Watt JA, Pike CJ, Walencewicz-Wasserman AJ, Cotman CW. Ultrastructural analysis of beta-amyloid-induced apoptosis in cultured hippocampal neurons. Brain Res 1994; 661: 147-56.
-
(1994)
Brain Res
, vol.661
, pp. 147-156
-
-
Watt, J.A.1
Pike, C.J.2
Walencewicz-Wasserman, A.J.3
Cotman, C.W.4
-
29
-
-
1642440245
-
Ergothioneine rescues PC12 cells from beta-amyloid-induced apoptotic death
-
Jang JH, Aruoma OI, Jen LS, Chung HY, Surh YJ. Ergothioneine rescues PC12 cells from beta-amyloid-induced apoptotic death. Free Radic Biol Med 2004; 36: 288-99.
-
(2004)
Free Radic Biol Med
, vol.36
, pp. 288-299
-
-
Jang, J.H.1
Aruoma, O.I.2
Jen, L.S.3
Chung, H.Y.4
Surh, Y.J.5
-
30
-
-
1242274383
-
Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death
-
Li R, Yang L, Lindholm K, Konishi Y, Yue X, Hampel H, et al. Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death. J Neurosci 2004; 24: 1760-71.
-
(2004)
J Neurosci
, vol.24
, pp. 1760-1771
-
-
Li, R.1
Yang, L.2
Lindholm, K.3
Konishi, Y.4
Yue, X.5
Hampel, H.6
-
31
-
-
0032508414
-
NF-kappaB antiapoptosis: Induction of TRF1 and TRF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
-
Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. NF-kappaB antiapoptosis: induction of TRF1 and TRF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 1998; 281: 1680-3.
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
Goeddel, D.V.4
Baldwin Jr., A.S.5
-
32
-
-
0030893610
-
Role of calpain- and interleukin-1 beta converting enzyme-like proteases in the beta-amyloid-induced death of rat hippocampal neurons in culture
-
Jordan J, Galindo MF, Miller RJ. Role of calpain- and interleukin-1 beta converting enzyme-like proteases in the beta-amyloid-induced death of rat hippocampal neurons in culture. J Neurochem 1997; 68: 1612-21.
-
(1997)
J Neurochem
, vol.68
, pp. 1612-1621
-
-
Jordan, J.1
Galindo, M.F.2
Miller, R.J.3
-
33
-
-
0032487648
-
Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites
-
Matson MP, Partin J, Begley JG. Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites. Brain Res 1998; 807: 167-76.
-
(1998)
Brain Res
, vol.807
, pp. 167-176
-
-
Matson, M.P.1
Partin, J.2
Begley, J.G.3
-
34
-
-
0032726814
-
Neuronal apoptosis induced by beta-amyloid is mediated by caspase-8
-
Ivins KJ, Tornton PL, Rohn T, Cotman CW. Neuronal apoptosis induced by beta-amyloid is mediated by caspase-8. Neurobiol Dis 1999; 6: 440-9.
-
(1999)
Neurobiol Dis
, vol.6
, pp. 440-449
-
-
Ivins, K.J.1
Tornton, P.L.2
Rohn, T.3
Cotman, C.W.4
-
35
-
-
52249112474
-
Mutated recombinant human glucagon-like peptide-1 protects SH-SY5Y cells from apoptosis induced by amyloid-beta peptide (1-42)
-
Qin Z, Sun Z, Huang J, Hu Y, Wu Z, Mei B. Mutated recombinant human glucagon-like peptide-1 protects SH-SY5Y cells from apoptosis induced by amyloid-beta peptide (1-42). Neurosci Let 2008; 444: 217-21.
-
(2008)
Neurosci Let
, vol.444
, pp. 217-221
-
-
Qin, Z.1
Sun, Z.2
Huang, J.3
Hu, Y.4
Wu, Z.5
Mei, B.6
-
37
-
-
0036830947
-
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
-
LaFerla FM. Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat Rev Neurosci 2002; 3: 862-72.
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 862-872
-
-
LaFerla, F.M.1
|