Growth hormone inhibition of glucose uptake in adipocytes occurs without affecting GLUT4 translocation through an insulin receptor substrate-2-phosphatidylinositol 3-kinase-dependent pathway

Journal of Biological Chemistry

Volumn 284, Issue 10, 2009, Pages 6061-6070

  Sasaki Suzuki, Naoko ^a,b,f   Arai, Kiyoshi ^a,g   Ogata, Tomomi ^a,h   Kasahara, Kouhei ^a   Sakoda, Hideyuki ^c   Chida, Kazuhiro ^a   Asano, Tomoichiro ^c,d   Pessin, Jeffrey E ^b,e   Hakuno, Fumihiko ^a   Takahashi, Shin Ichiro ^a,h  

^a UNIVERSITY OF TOKYO   (Japan)

^b STONY BROOK UNIVERSITY   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

^d HIROSHIMA UNIVERSITY   (Japan)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f Iwanaga Writers' Club LLC   (Japan)

^g Shinagawa R and D Center   (Japan)

^h KYORIN PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELL MEMBRANES; CHEMICAL ACTIVATION; GLUCOSE;

AKT PHOSPHORYLATION; CONSTITUTIVELY ACTIVES; INSULIN RESISTANCE; INSULIN-STIMULATED GLUCOSE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 3-KINASE; SMALL INTERFERING RNA; SPECIFIC INTERACTION;

INSULIN;

GLUCOSE TRANSPORTER 4; GROWTH HORMONE; INSULIN; INSULIN RECEPTOR SUBSTRATE 2; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; GLUCOSE; INSULIN RECEPTOR SUBSTRATE; IRS2 PROTEIN, MOUSE; SLC2A4 PROTEIN, MOUSE;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE OVEREXPRESSION; GENE TRANSLOCATION; GLUCOSE TRANSPORT; HORMONAL REGULATION; INSULIN RESISTANCE; MEMBRANE FUSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ANIMAL; CELL STRAIN 3T3; DRUG EFFECT; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TRANSPORT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3-L1 CELLS; ADIPOCYTES; ANIMALS; ENZYME ACTIVATION; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; GROWTH HORMONE; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MICE; PHOSPHORYLATION; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 65249086321     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808282200     Document Type: Article

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