Growth Hormone Induces Cellular Insulin Resistance by Uncoupling Phosphatidylinositol 3-Kinase and Its Downstream Signals in 3T3-L1 Adipocytes

Diabetes

Volumn 50, Issue 8, 2001, Pages 1891-1900

  Takano, Atsuko ^a   Haruta, Tetsuro ^a   Iwata, Minoru ^a   Usui, Isao ^a   Uno, Tatsuhito ^a   Kawahara, Junko ^a   Ueno, Eiichi ^a   Sasaoka, Toshiyasu ^a   Kobayashi, Masashi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AKT1 PROTEIN, HUMAN; DEOXYGLUCOSE; HUMAN GROWTH HORMONE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; JAK2 PROTEIN, HUMAN; JAK2 PROTEIN, MOUSE; JANUS KINASE 2; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN; PHOSPHOTYROSINE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; RECOMBINANT PROTEIN; SOMATOMEDIN C; STAT5B SERINE KINASE;

ADIPOCYTE; ANIMAL; ARTICLE; CELL LINE; CELL STRAIN 3T3; CYTOLOGY; CYTOSOL; DRUG EFFECT; GENETIC TRANSFECTION; HUMAN; INSULIN RESISTANCE; KINETICS; METABOLISM; MICROSOME; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION; SWINE; TRANSPORT AT THE CELLULAR LEVEL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3 CELLS; ADIPOCYTES; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CYTOSOL; DEOXYGLUCOSE; HUMAN GROWTH HORMONE; HUMANS; INSULIN; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR I; JANUS KINASE 2; KINETICS; MAP KINASE SIGNALING SYSTEM; MICE; MICROSOMES; PHOSPHOPROTEINS; PHOSPHOTYROSINE; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SWINE; TRANSFECTION;

EID: 0035430280     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.50.8.1891     Document Type: Article

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