Tyrosine kinase and phosphatidylinositol 3-kinase activation are required for cyclic adenosine 3′,5′-monophosphate-dependent potentiation of deoxyribonucleic acid synthesis induced by insulin-like growth factor-I in FRTL-5 cells

Endocrinology

Volumn 141, Issue 7, 2000, Pages 2429-2438

  Nedachi, Taku ^a   Akahori, Masakazu ^a   Ariga, Miyako ^a   Sakamoto, Hideki ^a   Suzuki, Naoko ^a   Umesaki, Kohta ^a   Hakuno, Fumihiko ^a   Takahashi, Shin Ichiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CELL PROTEIN; CYCLIC AMP; DNA; GENISTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SOMATOMEDIN C; THYROTROPIN;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL LYSATE; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME MECHANISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

EID: 0034457005     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.141.7.7539     Document Type: Article

References (41)

1. Mouse models of IGF-I deficiency generated by gene targeting
2. Gene-targeting and transgenic approaches to IGF and IGF binding protein function
3. Use of transgenic mice for understanding the physiology of insulin-like growth factors
4. The role of somato-medins in the growth and function of endocrine tissues
5. Biological actions of the insulin-like growth factors
6. Insulin-like growth factors and their binding proteins: Biological actions
7. Adenosine 3′, 5′-monophosphate mediates both the mitogenic effect of thyrotropin and its ability to amplify the response to insulin-like growth factor I in FRTL-5 cells
8. Thyrotropin potentiation of insulin-like growth factor-I dependent deoxyribonucleic acid synthesis in FRTL-5 cells: Mediation by an autocrine amplification factor(s)
9. Somatomedin-C synergies with follicle-stimulating hormone in the acquisition of progestin biosynthetic capacity by cultured rat granulosa cells
10. Somatomedin-C-mediated potentiation of follicle-stimulating hormone-induced aromatase activity of cultured rat granulosa cells
11. Independent and synergistic actions of somatomedin-C in the stimulation of proteoglycan biosynthesis in cultured rat granulosa cells
12. Culture of hormone-dependent functional epithelial cells from rat thyroid
13. Iodine transport in continuous line of cultured cells from rat thyroid
14. Thyroglobulin gene expression is regulated by insulin and insulin-like growth factor I, as well as thyrotropin, in FRTL-5 thyroid cells
15. Role of non-TSH factors in thyroid cell growth
16. Growth hormone does not increase thyroid size in the absence of thyrotropin: A study in adults with hypopituitarism
17. The thyroid gland in acromegaly: An ultrasonographic study
18. Thyrotropin and insulin-like growth factor I regulation of tyrosine phosphorytation in FRTL-5 cells
19. Application of Bradford's protein assay to adrenal gland subcellular fractions
20. Tyrosine protein kinase activity during embryogenesis
21. Insulin and insulin-like growth factor-I receptors similarly stimulate deoxyribonucleic acid synthesis despite differences in cellular protein tyrosine phosphorylation
22. Protein (serine and threonine) phosphate phosphatases
23. Interaction between cAMP-dependent and insulin-dependent signal pathways in tyrosine phosphorylation in primary cultures of rat hepatocytes
24. A Grb2-associated docking protein in EGF- and insulin-receptor signalling
25. Changes in tyrosine phosphorylation of insulin receptor and insulin receptor substrate-1 (IRS-1) and association of p85 subunit of phosphatidylinoshitol 3-kinase with IRS-1 after feeding in rat liver in vivo
26. Association of phosphatidylinositol kinase activity with polyoma middte-T competent for transformation
27. 2+ influx induced by BAY K8644 in FRTL-5 cells
28. Functions of SH2 and SH3 domains
29. Function of PTB domains
30. SH2 and PTB domain interactions in tyrosine kinase signal transduction
31. Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunit
32. Specific phosphopeptide binding regulates a conformational change in the PI 3-kinase SH2 domain associated with enzyme activation
33. Structure and function of phosphatidylinositol 3-kinase: A potential second messenger system involved in growth control
34. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
35. A target for phosphoinositide 3-kinase: Akt/PKB
36. Signal transduction. A target for PI (3) kinase
37. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
38. ras
39. Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways
40. Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase
41. The roles of genistein-sensitive tyrosine kinases and PI 3-kinase in cAMP-dependent regulation of cyclin/CDK inhibitor/CDK system in FRTL-5 cells