Progressive thalamocortical neuron loss in Cln5 deficient mice: Distinct effects in Finnish variant late infantile NCL

Neurobiology of Disease

Volumn 34, Issue 2, 2009, Pages 308-319

  von Schantz, Carina ^a   Kielar, Catherine ^b   Hansen, Stine N ^b   Pontikis, Charlie C ^b   Alexander, Noreen A ^b   Kopra, Outi ^c   Jalanko, Anu ^a   Cooper, Jonathan D ^b  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b Centre for the Cellular Basis of Behaviour   (United Kingdom)

^c FOLKHÄLSAN INSTITUTE OF GENETICS   (Finland)

Author keywords

Batten disease; CLN5; Finnish variant late infantile neuronal ceroid lipofuscinosis; Lysosomal storage disorder; Thalamocortical neurodegeneration

Indexed keywords

CLN5 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ATROPHY; BRAIN CORTEX; CELL LOSS; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DISEASE COURSE; GLIA CELL; MALE; MOUSE; NERVE CELL; NEURONAL CEROID LIPOFUSCINOSIS; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; STEREOMETRY; SYNAPSE; THALAMOCORTICAL TRACT; THALAMUS NUCLEUS; VISUAL SYSTEM;

AGE OF ONSET; ANIMALS; ATROPHY; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FINLAND; GENETIC PREDISPOSITION TO DISEASE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; NERVE DEGENERATION; NEURAL PATHWAYS; NEURONAL CEROID-LIPOFUSCINOSES; THALAMUS; VISUAL PATHWAYS;

EID: 64649097377     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2009.02.001     Document Type: Article

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