Targeted disruption of the Cln3 gene provides a mouse model for Batten disease

Neurobiology of Disease

Volumn 6, Issue 5, 1999, Pages 321-334

  Mitchison, Hannah M ^a   Bernard, David J ^b   Greene, Nicholas D E ^a   Cooper, Jonathan D ^c   Junaid, Mohammed A ^d   Pullarkat, Raju K ^d   De Vos, Nanneke ^e   Breuning, Martijn H ^e   Owens, Jennie W ^f   Mobley, William C ^c   Gardiner, R Mark ^a   Lake, Brian D ^g   Taschner, Peter E M ^e   Nussbaum, Robert L ^b  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c STANFORD UNIVERSITY   (United States)

^d NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^e LEIDEN UNIVERSITY   (Netherlands)

^f NATIONAL INSTITUTES OF HEALTH   (United States)

^g GREAT ORMOND STREET HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOFLUORESCENCE; CELL LOSS; ELECTRON MICROSCOPY; ENZYME ACTIVITY; FEMALE; GENE DISRUPTION; GENE MUTATION; GENE TARGETING; HIPPOCAMPUS; HOMOZYGOSITY; HYPERTROPHY; MALE; MOUSE; NEURONAL CEROID LIPOFUSCINOSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0032744277     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1006/nbdi.1999.0267     Document Type: Article

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