Brain gene expression profiles of Cln1 and Cln5 deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases

BMC Genomics

Volumn 9, Issue , 2008, Pages

  von Schantz, Carina ^a   Saharinen, Juha ^a   Kopra, Outi ^a,b   Cooper, Jonathan D ^c   Gentile, Massimiliano ^a   Hovatta, Iiris ^a   Peltonen, Leena ^a,d   Jalanko, Anu ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b FOLKHÄLSAN INSTITUTE OF GENETICS   (Finland)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ADENYLATE CYCLASE; BETA TUBULIN; CONTACTIN; CYTOSKELETON PROTEIN; G PROTEIN COUPLED RECEPTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; KINESIN; MEMBRANE PROTEIN; NEUROMODULIN; PALMITOYL PROTEIN THIOESTERASE; PROTEIN CDC42; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE 4A2; RAB PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RNA BINDING PROTEIN; SYNAPSIN; TYROSINE KINASE RECEPTOR; CLN5 PROTEIN, MOUSE; IMMEDIATE EARLY PROTEIN; PALMITOYL-PROTEIN THIOESTERASE; PTP4A2 PROTEIN, MOUSE; PTPRF PROTEIN, MOUSE; RECEPTOR LIKE PROTEIN TYROSINE PHOSPHATASE; THIOL ESTER HYDROLASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLINDNESS; BRAIN CELL; BRAIN CORTEX; BRAIN CORTEX ATROPHY; CONTROLLED STUDY; DEGENERATIVE DISEASE; DEMENTIA; DISEASE COURSE; DISEASE MODEL; GENE EXPRESSION PROFILING; GENE MUTATION; GENETIC REGULATION; GROWTH CONE; IMMUNOFLUORESCENCE; MICROARRAY ANALYSIS; MOLECULAR MECHANICS; MOUSE; NERVE CELL DEGENERATION; NERVE CELL GROWTH; NEURONAL CEROID LIPOFUSCINOSIS; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PATHOPHYSIOLOGY; PHENOTYPE; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; UNINDEXED SEQUENCE; ANIMAL; BRAIN; CELL CULTURE; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; IMMUNOHISTOCHEMISTRY; METABOLISM; MOUSE MUTANT; PATHOLOGY; WESTERN BLOTTING;

MUS;

ADENYLATE CYCLASE; ANIMALS; BLOTTING, WESTERN; BRAIN; CELLS, CULTURED; GAP-43 PROTEIN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOTYPE; GROWTH CONES; IMMEDIATE-EARLY PROTEINS; IMMUNOHISTOCHEMISTRY; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; NEURONAL CEROID-LIPOFUSCINOSES; PROTEIN TYROSINE PHOSPHATASES; RAB3 GTP-BINDING PROTEINS; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 2; SYNAPSINS; THIOLESTER HYDROLASES;

EID: 43449115394     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-9-146     Document Type: Article

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