Physicochemical and biological characterization of monoketocholic acid, a novel permeability enhancer

Molecular Pharmaceutics

Volumn 6, Issue 2, 2009, Pages 448-456

  Yang, Lin ^a   Zhang, Hu ^a   Mikov, Momir ^a   Tucker, Ian G ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

BBB; Bile salts; Biological membrane; Caco 2; Hemolysis; Langmuir monolayer; Monoketocholate; Permeability

Indexed keywords

BILE SALT; CHOLIC ACID; DEOXYCHOLIC ACID; DIPALMITOYLPHOSPHATIDYLCHOLINE; MANNITOL; MONOKETOCHOLATE; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN CACO 2; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; DRUG PENETRATION; DRUG SYNTHESIS; ELECTRIC RESISTANCE; ERYTHROCYTE DEFORMABILITY; HEMOLYSIS; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; NONHUMAN; PARTITION COEFFICIENT; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; RAT; SYNTHESIS;

ANIMALS; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; CHOLIC ACID; DEOXYCHOLIC ACID; ELECTRIC IMPEDANCE; ERYTHROCYTES; HEMOLYSIS; HUMANS; MANNITOL; MICELLES; RATS; TAUROCHOLIC ACID;

EID: 64649093413     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp800143w     Document Type: Article

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