메뉴 건너뛰기




Volumn 36, Issue 5, 2009, Pages 791-800

Molecular imaging of α7 nicotinic acetylcholine receptors: Design and evaluation of the potent radioligand [18F]NS10743

Author keywords

Alpha7 nicotinic acetylcholine receptors; Diagnostic imaging; Diazabicyclononane; Neurology; Nonneuronal; Oncology; PET

Indexed keywords

1,4 DIAZABICYCLO [3.2.2]NONANE; 1,4 DIAZABICYCLO[3.2.2]NONANE 4 CARBOXYLIC ACID 4 BROMOPHENYL ESTER; BUNGAROTOXIN RECEPTOR; DRUG METABOLITE; EPIBATIDINE; FLUORODEOXYGLUCOSE F 18; IODINE 125; NICOTINIC AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA3BETA4; NICOTINIC RECEPTOR ALPHA4BETA2; NS 10743; NS 10743 F 18; RADIOLIGAND; SEROTONIN 3 RECEPTOR; UNCLASSIFIED DRUG; ALPHA-BUNGAROTOXIN RECEPTOR; FUSED HETEROCYCLIC RINGS; RADIOPHARMACEUTICAL AGENT;

EID: 64649086752     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-008-1031-7     Document Type: Article
Times cited : (36)

References (59)
  • 1
    • 0027999947 scopus 로고
    • Immunocytochemical localization of the α7 subunit of the nicotinic acetylcholine receptor in the rat central nervous system
    • E Dominguez del Toro JM Juiz X Peng J Lindström M Criado 1994 Immunocytochemical localization of the α7 subunit of the nicotinic acetylcholine receptor in the rat central nervous system J Comp Neurol 349 325 342
    • (1994) J Comp Neurol , vol.349 , pp. 325-342
    • Dominguez Del Toro, E.1    Juiz, J.M.2    Peng, X.3    Lindström, J.4    Criado, M.5
  • 2
    • 2542486433 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors and the regulation of neuronal signalling
    • F Dajas-Bailador S Wonnacott 2004 Nicotinic acetylcholine receptors and the regulation of neuronal signalling Trends Pharmacol Sci 25 317 324
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 317-324
    • Dajas-Bailador, F.1    Wonnacott, S.2
  • 3
    • 22844432580 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptors: Structural revelations, target identifications, and therapeutic inspirations
    • AA Jensen B Frolund T Liljefors P Krogsgaard-Larsen 2005 Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations J Med Chem 48 4705 4745
    • (2005) J Med Chem , vol.48 , pp. 4705-4745
    • Jensen, A.A.1    Frolund, B.2    Liljefors, T.3    Krogsgaard-Larsen, P.4
  • 4
    • 33747125503 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptor expression and function on nonneuronal cells
    • LC Gahring SW Rogers 2006 Neuronal nicotinic acetylcholine receptor expression and function on nonneuronal cells AAPS J 7 E885 E894
    • (2006) AAPS J , vol.7
    • Gahring, L.C.1    Rogers, S.W.2
  • 5
    • 0035957403 scopus 로고    scopus 로고
    • Nicotinic cholinergic signaling in hippocampal astrocytes involves calcium-induced calcium release from intracellular stores
    • G Sharma S Vijayaraghavan 2001 Nicotinic cholinergic signaling in hippocampal astrocytes involves calcium-induced calcium release from intracellular stores Proc Natl Acad Sci U S A 98 4148 4153
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4148-4153
    • Sharma, G.1    Vijayaraghavan, S.2
  • 6
    • 4744354513 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor immunohistochemistry in Alzheimer's disease and dementia with Lewy bodies: Differential neuronal and astroglial pathology
    • T Teaktong AJ Graham JA Court RH Perry E Jaros M Johnson 2004 Nicotinic acetylcholine receptor immunohistochemistry in Alzheimer's disease and dementia with Lewy bodies: differential neuronal and astroglial pathology J Neurol Sci 225 39 49
    • (2004) J Neurol Sci , vol.225 , pp. 39-49
    • Teaktong, T.1    Graham, A.J.2    Court, J.A.3    Perry, R.H.4    Jaros, E.5    Johnson, M.6
  • 7
    • 0036890808 scopus 로고    scopus 로고
    • Nicotinic α7 receptors: Synaptic options and downstream signaling in neurons
    • DK Berg WG Conroy 2002 Nicotinic α7 receptors: synaptic options and downstream signaling in neurons J Neurobiol 53 512 523
    • (2002) J Neurobiol , vol.53 , pp. 512-523
    • Berg, D.K.1    Conroy, W.G.2
  • 8
    • 0035983529 scopus 로고    scopus 로고
    • Intracellular Ca2+ signals evoked by stimulation of nicotinic acetylcholine receptors in SH-SY5Y cells: Contribution of voltage-operated Ca2+ channels and Ca2+ stores
    • FA Dajas-Bailador AJ Mogg S Wonnacott 2002 Intracellular Ca2+ signals evoked by stimulation of nicotinic acetylcholine receptors in SH-SY5Y cells: contribution of voltage-operated Ca2+ channels and Ca2+ stores J Neurochem 81 606 614
    • (2002) J Neurochem , vol.81 , pp. 606-614
    • Dajas-Bailador, F.A.1    Mogg, A.J.2    Wonnacott, S.3
  • 9
    • 34548696176 scopus 로고    scopus 로고
    • Age-dependent changes in the functional expression of two nicotinic receptor subtypes in CA1 stratum radiatum interneurons in the rat hippocampus
    • M Alkondon EF Pereira EX Albuquerque 2007 Age-dependent changes in the functional expression of two nicotinic receptor subtypes in CA1 stratum radiatum interneurons in the rat hippocampus Biochem Pharmacol 74 1134 1144
    • (2007) Biochem Pharmacol , vol.74 , pp. 1134-1144
    • Alkondon, M.1    Pereira, E.F.2    Albuquerque, E.X.3
  • 10
    • 0030884260 scopus 로고    scopus 로고
    • Comparison of the regional expression of nicotinic acetylcholine receptor α7 mRNA and [125I]-α-bungarotoxin binding in human postmortem brain
    • CR Breese C Adams J Logel C Drebing Y Rollins M Barnhart 1997 Comparison of the regional expression of nicotinic acetylcholine receptor α7 mRNA and [125I]-α-bungarotoxin binding in human postmortem brain J Comp Neurol 387 385 398
    • (1997) J Comp Neurol , vol.387 , pp. 385-398
    • Breese, C.R.1    Adams, C.2    Logel, J.3    Drebing, C.4    Rollins, Y.5    Barnhart, M.6
  • 11
    • 34250640213 scopus 로고    scopus 로고
    • Cholinergic axons modulate GABAergic signaling among hippocampal interneurons via postsynaptic α7 nicotinic receptors
    • N Wanaverbecq A Semyanov I Pavlov MC Walker DM Kullmann 2007 Cholinergic axons modulate GABAergic signaling among hippocampal interneurons via postsynaptic α7 nicotinic receptors J Neurosci 27 5683 5693
    • (2007) J Neurosci , vol.27 , pp. 5683-5693
    • Wanaverbecq, N.1    Semyanov, A.2    Pavlov, I.3    Walker, M.C.4    Kullmann, D.M.5
  • 12
    • 33845994435 scopus 로고    scopus 로고
    • Partial agonists as therapeutic agents at neuronal nicotinic acetylcholine receptors
    • RC Hogg D Bertrand 2007 Partial agonists as therapeutic agents at neuronal nicotinic acetylcholine receptors Biochem Pharmacol 73 459 468
    • (2007) Biochem Pharmacol , vol.73 , pp. 459-468
    • Hogg, R.C.1    Bertrand, D.2
  • 13
    • 33845894963 scopus 로고    scopus 로고
    • Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms
    • G Mudo N Belluardo K Fuxe 2007 Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms J Neural Transm 114 135 147
    • (2007) J Neural Transm , vol.114 , pp. 135-147
    • Mudo, G.1    Belluardo, N.2    Fuxe, K.3
  • 15
    • 0038360749 scopus 로고    scopus 로고
    • Loss of nicotinic acetylcholine receptor subunits α4 and α7 in the cerebral cortex of Parkinson patients
    • L Burghaus U Schütz U Krempel J Lindstrom H Schröder 2003 Loss of nicotinic acetylcholine receptor subunits α4 and α7 in the cerebral cortex of Parkinson patients Parkinsonism Relat Disord 9 243 246
    • (2003) Parkinsonism Relat Disord , vol.9 , pp. 243-246
    • Burghaus, L.1    Schütz, U.2    Krempel, U.3    Lindstrom, J.4    Schröder, H.5
  • 16
    • 0037461768 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation
    • H Wang M Yu M Ochani CA Amella M Tanovic S Susarla 2003 Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation Nature 421 384 388
    • (2003) Nature , vol.421 , pp. 384-388
    • Wang, H.1    Yu, M.2    Ochani, M.3    Amella, C.A.4    Tanovic, M.5    Susarla, S.6
  • 17
    • 40149104224 scopus 로고    scopus 로고
    • Alpha7 nicotinic acetylcholine receptor: A link between inflammation and neurodegeneration
    • C Conejero-Goldberg P Davies L Ulloa 2008 Alpha7 nicotinic acetylcholine receptor: a link between inflammation and neurodegeneration Neurosci Biobehav Rev 32 693 706
    • (2008) Neurosci Biobehav Rev , vol.32 , pp. 693-706
    • Conejero-Goldberg, C.1    Davies, P.2    Ulloa, L.3
  • 18
    • 39749152191 scopus 로고    scopus 로고
    • Allosteric modulators of the α7 nicotinic acetylcholine receptor
    • R Faghih M Gopalakrishnan CA Briggs 2008 Allosteric modulators of the α7 nicotinic acetylcholine receptor J Med Chem 51 701 712
    • (2008) J Med Chem , vol.51 , pp. 701-712
    • Faghih, R.1    Gopalakrishnan, M.2    Briggs, C.A.3
  • 19
    • 33744726880 scopus 로고    scopus 로고
    • Selective α7 nicotinic acetylcholine receptor ligands
    • A Mazurov T Hauser CH Miller 2006 Selective α7 nicotinic acetylcholine receptor ligands Curr Med Chem 13 1567 1584
    • (2006) Curr Med Chem , vol.13 , pp. 1567-1584
    • Mazurov, A.1    Hauser, T.2    Miller, C.H.3
  • 20
    • 39749147634 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors in cancer: Multiple roles in proliferation and inhibition of apoptosis
    • RD Egleton KC Brown P Dasgupta 2008 Nicotinic acetylcholine receptors in cancer: multiple roles in proliferation and inhibition of apoptosis Trends Pharmacol Sci 29 151 158
    • (2008) Trends Pharmacol Sci , vol.29 , pp. 151-158
    • Egleton, R.D.1    Brown, K.C.2    Dasgupta, P.3
  • 21
    • 24344492234 scopus 로고    scopus 로고
    • Expression of the alpha7 nicotinic acetylcholine receptor in human lung cells
    • HK Plummer 3rd M Dhar HM Schuller 2005 Expression of the alpha7 nicotinic acetylcholine receptor in human lung cells Respir Res 6 29
    • (2005) Respir Res , vol.6 , pp. 29
    • Plummer III, H.K.1    Dhar, M.2    Schuller, H.M.3
  • 22
    • 34249776345 scopus 로고    scopus 로고
    • Nicotine promotes cell proliferation via α7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells
    • HP Wong L Yu EK Lam EK Tai WK Wu CH Cho 2007 Nicotine promotes cell proliferation via α7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells Toxicol Appl Pharmacol 221 261 267
    • (2007) Toxicol Appl Pharmacol , vol.221 , pp. 261-267
    • Wong, H.P.1    Yu, L.2    Lam, E.K.3    Tai, E.K.4    Wu, W.K.5    Cho, C.H.6
  • 23
    • 0037470621 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor subunits and receptor activity in the epithelial cell line HT29
    • AE Summers CJ Whelan ME Parsons 2003 Nicotinic acetylcholine receptor subunits and receptor activity in the epithelial cell line HT29 Life Sci 72 2091 2094
    • (2003) Life Sci , vol.72 , pp. 2091-2094
    • Summers, A.E.1    Whelan, C.J.2    Parsons, M.E.3
  • 24
    • 33847381505 scopus 로고    scopus 로고
    • Neurotransmitter receptor-mediated signaling pathways as modulators of carcinogenesis
    • HM Schuller 2007 Neurotransmitter receptor-mediated signaling pathways as modulators of carcinogenesis Prog Exp Tumor Res 39 45 63
    • (2007) Prog Exp Tumor Res , vol.39 , pp. 45-63
    • Schuller, H.M.1
  • 25
    • 0034719376 scopus 로고    scopus 로고
    • Synthesis and pharmacological characterization of [125I] iodomethyllycaconitine ([125I]Iodo-MLA). A new ligand for the α7 nicotinic acetylcholine receptor
    • HA Navarro D Zhong P Abraham H Xu FI Carroll 2000 Synthesis and pharmacological characterization of [125I]iodomethyllycaconitine ([125I]Iodo-MLA). A new ligand for the α7 nicotinic acetylcholine receptor J Med Chem 43 142 145
    • (2000) J Med Chem , vol.43 , pp. 142-145
    • Navarro, H.A.1    Zhong, D.2    Abraham, P.3    Xu, H.4    Carroll, F.I.5
  • 26
    • 0037013704 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of [125I]iodomethyllycaconitine in the rat
    • HA Navarro H Xu D Zhong P Abraham FI Carroll 2002 In vitro and in vivo characterization of [125I]iodomethyllycaconitine in the rat Synapse 44 117 123
    • (2002) Synapse , vol.44 , pp. 117-123
    • Navarro, H.A.1    Xu, H.2    Zhong, D.3    Abraham, P.4    Carroll, F.I.5
  • 27
    • 0035888271 scopus 로고    scopus 로고
    • Synthesis and preliminary evaluation of a carbon-11-labelled agonist of the α7 nicotinic acetylcholine receptor
    • F Dolle H Valette F Hinnen F Vaufrey S Demphel C Coulon 2001 Synthesis and preliminary evaluation of a carbon-11-labelled agonist of the α7 nicotinic acetylcholine receptor J Label Compd Radiopharm 44 785 795
    • (2001) J Label Compd Radiopharm , vol.44 , pp. 785-795
    • Dolle, F.1    Valette, H.2    Hinnen, F.3    Vaufrey, F.4    Demphel, S.5    Coulon, C.6
  • 28
    • 15844383142 scopus 로고    scopus 로고
    • Synthesis and biodistribution of radiolabeled α7 nicotinic acetylcholine receptor ligands
    • MG Pomper E Phillips H Fan DJ McCarthy RA Keith JC Gordon 2005 Synthesis and biodistribution of radiolabeled α7 nicotinic acetylcholine receptor ligands J Nucl Med 46 326 334
    • (2005) J Nucl Med , vol.46 , pp. 326-334
    • Pomper, M.G.1    Phillips, E.2    Fan, H.3    Keith, R.A.4    Gordon, J.C.5
  • 29
    • 33646046814 scopus 로고    scopus 로고
    • Synthesis and evaluation of [125I]I-TSA as a brain nicotinic acetylcholine receptor α7 subtype imaging agent
    • M Ogawa R Tatsumi M Fujio J Katayama Y Magata 2006 Synthesis and evaluation of [125I]I-TSA as a brain nicotinic acetylcholine receptor α7 subtype imaging agent Nucl Med Biol 33 311 316
    • (2006) Nucl Med Biol , vol.33 , pp. 311-316
    • Ogawa, M.1    Tatsumi, R.2    Fujio, M.3    Katayama, J.4    Magata, Y.5
  • 30
    • 34250708060 scopus 로고    scopus 로고
    • Synthesis and positron emission tomography studies of C-11-labeled isotopomers and metabolites of GTS-21, a partial α7 nicotinic cholinergic agonist drug
    • SW Kim YS Ding D Alexoff V Patel J Logan KS Lin 2007 Synthesis and positron emission tomography studies of C-11-labeled isotopomers and metabolites of GTS-21, a partial α7 nicotinic cholinergic agonist drug Nucl Med Biol 34 541 551
    • (2007) Nucl Med Biol , vol.34 , pp. 541-551
    • Kim, S.W.1    Ding, Y.S.2    Alexoff, D.3    Patel, V.4    Logan, J.5    Lin, K.S.6
  • 31
    • 1642321246 scopus 로고    scopus 로고
    • Design of ligands for the nicotinic acetylcholine receptors: The quest for selectivity
    • WH Bunnelle MJ Dart MR Schrimpf 2004 Design of ligands for the nicotinic acetylcholine receptors: the quest for selectivity Curr Top Med Chem 4 299 334
    • (2004) Curr Top Med Chem , vol.4 , pp. 299-334
    • Bunnelle, W.H.1    Dart, M.J.2    Schrimpf, M.R.3
  • 36
    • 52449083063 scopus 로고    scopus 로고
    • [11C]CHIBA-1001 as a novel PET ligand for α7 nicotinic receptors in the brain: A PET study in conscious monkeys
    • K Hashimoto S Nishiyama H Ohba M Matsuo T Kobashi M Takahagi 2008 [11C]CHIBA-1001 as a novel PET ligand for α7 nicotinic receptors in the brain: a PET study in conscious monkeys PLoS ONE 3 e3231
    • (2008) PLoS ONE , vol.3 , pp. 3231
    • Hashimoto, K.1    Nishiyama, S.2    Ohba, H.3    Matsuo, M.4    Kobashi, T.5    Takahagi, M.6
  • 37
    • 0023902147 scopus 로고
    • Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists
    • RC Young RC Mitchell TH Brown CR Ganellin R Griffiths M Jones 1988 Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists J Med Chem 31 656 671
    • (1988) J Med Chem , vol.31 , pp. 656-671
    • Young, R.C.1    Mitchell, R.C.2    Brown, T.H.3    Ganellin, C.R.4    Griffiths, R.5    Jones, M.6
  • 38
    • 5044235132 scopus 로고    scopus 로고
    • Norchloro-fluoro-homoepibatidine: Specificity to neuronal nicotinic acetylcholine receptor subtypes in vitro
    • W Deuther-Conrad JT Patt D Feuerbach F Wegner P Brust J Steinbach 2004 Norchloro-fluoro-homoepibatidine: specificity to neuronal nicotinic acetylcholine receptor subtypes in vitro Farmaco 59 785 792
    • (2004) Farmaco , vol.59 , pp. 785-792
    • Deuther-Conrad, W.1    Patt, J.T.2    Feuerbach, D.3    Wegner, F.4    Brust, P.5    Steinbach, J.6
  • 39
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (IC50) of an enzymatic reaction
    • Y Cheng WH Prusoff 1973 Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (IC50) of an enzymatic reaction Biochem Pharmacol 22 3099 3108
    • (1973) Biochem Pharmacol , vol.22 , pp. 3099-3108
    • Cheng, Y.1    Prusoff, W.H.2
  • 40
    • 0030636321 scopus 로고    scopus 로고
    • Analysis of data from "Cold Saturation" radioligand binding experiments
    • WB Jeffries D Waugh PW Abel 1997 Analysis of data from "Cold Saturation" radioligand binding experiments Methods Mol Biol 73 331 342
    • (1997) Methods Mol Biol , vol.73 , pp. 331-342
    • Jeffries, W.B.1    Waugh, D.2    Abel, P.W.3
  • 42
  • 44
    • 0035172092 scopus 로고    scopus 로고
    • Identification of human drug-metabolizing enzymes involved in the metabolism of SNI-2011
    • T Washio H Arisawa K Kohsaka H Yasuda 2001 Identification of human drug-metabolizing enzymes involved in the metabolism of SNI-2011 Biol Pharm Bull 24 1263 1266
    • (2001) Biol Pharm Bull , vol.24 , pp. 1263-1266
    • Washio, T.1    Arisawa, H.2    Kohsaka, K.3    Yasuda, H.4
  • 45
    • 34250768949 scopus 로고    scopus 로고
    • Metabolism and disposition of a selective α7 nicotinic acetylcholine receptor agonist in humans
    • CL Shaffer M Gunduz RJ Scialis AF Fang 2007 Metabolism and disposition of a selective α7 nicotinic acetylcholine receptor agonist in humans Drug Metab Dispos 35 1188 1195
    • (2007) Drug Metab Dispos , vol.35 , pp. 1188-1195
    • Shaffer, C.L.1    Gunduz, M.2    Scialis, R.J.3    Fang, A.F.4
  • 46
    • 47149106256 scopus 로고    scopus 로고
    • Preclinical characterization of A-582941: A novel α7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties
    • KR Tietje DJ Anderson RS Bitner EA Blomme PJ Brackemeyer CA Briggs 2008 Preclinical characterization of A-582941: a novel α7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties CNS Neurosci Ther 14 65 82
    • (2008) CNS Neurosci Ther , vol.14 , pp. 65-82
    • Tietje, K.R.1    Anderson, D.J.2    Bitner, R.S.3    Blomme, E.A.4    Brackemeyer, P.J.5    Briggs, C.A.6
  • 47
    • 45649085042 scopus 로고    scopus 로고
    • Ex vivo assessment of binding site occupancy of monoamine reuptake inhibitors: Methodology and biological significance
    • K Lengyel R Pieschl T Strong T Molski G Mattson NJ Lodge 2008 Ex vivo assessment of binding site occupancy of monoamine reuptake inhibitors: methodology and biological significance Neuropharmacology 55 63 70
    • (2008) Neuropharmacology , vol.55 , pp. 63-70
    • Lengyel, K.1    Pieschl, R.2    Strong, T.3    Molski, T.4    Mattson, G.5    Lodge, N.J.6
  • 50
    • 0031731788 scopus 로고    scopus 로고
    • Postnatal changes of nicotinic acetylcholine receptor α2, α3, α4, α7 and β2 subunits genes expression in rat brain
    • X Zhang C Liu H Miao ZH Gong A Nordberg 1998 Postnatal changes of nicotinic acetylcholine receptor α2, α3, α4, α7 and β2 subunits genes expression in rat brain Int J Dev Neurosci 16 507 518
    • (1998) Int J Dev Neurosci , vol.16 , pp. 507-518
    • Zhang, X.1    Liu, C.2    Miao, H.3    Gong, Z.H.4    Nordberg, A.5
  • 51
    • 0032818891 scopus 로고    scopus 로고
    • An autoradiographic study of the distribution of binding sites for the novel α7-selective nicotinic radioligand [3H]-methyllycaconitine in the mouse brain
    • P Whiteaker AR Davies MJ Marks IS Blagbrough BV Potter AJ Wolstenholme 1999 An autoradiographic study of the distribution of binding sites for the novel α7-selective nicotinic radioligand [3H]-methyllycaconitine in the mouse brain Eur J Neurosci 11 2689 2696
    • (1999) Eur J Neurosci , vol.11 , pp. 2689-2696
    • Whiteaker, P.1    Davies, A.R.2    Marks, M.J.3    Blagbrough, I.S.4    Potter, B.V.5    Wolstenholme, A.J.6
  • 52
    • 34548043043 scopus 로고    scopus 로고
    • Time dependent decreases in central α7 nicotinic acetylcholine receptors associated with haloperidol and risperidone treatment in rats
    • AV Terry Jr DA Gearhart 2007 Time dependent decreases in central α7 nicotinic acetylcholine receptors associated with haloperidol and risperidone treatment in rats Eur J Pharmacol 571 29 32
    • (2007) Eur J Pharmacol , vol.571 , pp. 29-32
    • Terry Jr, A.V.1    Gearhart, D.A.2
  • 53
    • 0021909380 scopus 로고
    • Nicotinic binding in rat brain: Autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-α-bungarotoxin
    • PB Clarke RD Schwartz SM Paul CB Pert A Pert 1985 Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-α-bungarotoxin J Neurosci 5 1307 1315
    • (1985) J Neurosci , vol.5 , pp. 1307-1315
    • Clarke, P.B.1    Schwartz, R.D.2    Paul, S.M.3    Pert, C.B.4    Pert, A.5
  • 55
    • 0037008863 scopus 로고    scopus 로고
    • Immunohistochemical localisation of nicotinic acetylcholine receptor subunits in human cerebellum
    • A Graham JA Court CM Martin-Ruiz E Jaros R Perry SG Volsen 2002 Immunohistochemical localisation of nicotinic acetylcholine receptor subunits in human cerebellum Neuroscience 113 493 507
    • (2002) Neuroscience , vol.113 , pp. 493-507
    • Graham, A.1    Court, J.A.2    Martin-Ruiz, C.M.3    Jaros, E.4    Perry, R.5    Volsen, S.G.6
  • 56
    • 38549086800 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors of adrenal chromaffin cells
    • F Sala A Nistri M Criado 2008 Nicotinic acetylcholine receptors of adrenal chromaffin cells Acta Physiol (Oxf) 192 203 212
    • (2008) Acta Physiol (Oxf) , vol.192 , pp. 203-212
    • Sala, F.1    Nistri, A.2    Criado, M.3
  • 57
    • 29244447695 scopus 로고    scopus 로고
    • The role of nicotinic acetylcholine receptors in lymphocyte development
    • M Skok R Grailhe F Agenes JP Changeux 2006 The role of nicotinic acetylcholine receptors in lymphocyte development J Neuroimmunol 171 86 98
    • (2006) J Neuroimmunol , vol.171 , pp. 86-98
    • Skok, M.1    Grailhe, R.2    Agenes, F.3    Changeux, J.P.4
  • 58
    • 0031963193 scopus 로고    scopus 로고
    • Immunohistochemical localization of nicotinic acetylcholine receptors in the guinea pig bowel and pancreas
    • AL Kirchgessner MT Liu 1998 Immunohistochemical localization of nicotinic acetylcholine receptors in the guinea pig bowel and pancreas J Comp Neurol 390 497 514
    • (1998) J Comp Neurol , vol.390 , pp. 497-514
    • Kirchgessner, A.L.1    Liu, M.T.2
  • 59
    • 34249337063 scopus 로고    scopus 로고
    • The role of nicotinic receptors in B-lymphocyte development and activation
    • MV Skok R Grailhe F Agenes JP Changeux 2007 The role of nicotinic receptors in B-lymphocyte development and activation Life Sci 80 2334 2336
    • (2007) Life Sci , vol.80 , pp. 2334-2336
    • Skok, M.V.1    Grailhe, R.2    Agenes, F.3    Changeux, J.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.